George Scheffer

19952018

Research output per year

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Research Output

Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide

Oerlemans, R., Berkers, C. R., Assaraf, Y. G., Scheffer, G. L., Peters, G. J., Verbrugge, S. E., Cloos, J., Slootstra, J., Meloen, R. H., Shoemaker, R. H., Dijkmans, B. A. C., Scheper, R. J., Ovaa, H. & Jansen, G., 1 Oct 2018, In : Investigational New Drugs. 36, 5, p. 797-809 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study

Bosch, L. J. W., De Wit, M., Pham, T. V., Coupé, V. M. H., Hiemstra, A. C., Piersma, S. R., Oudgenoeg, G., Scheffer, G. L., Mongera, S., Droste, J. T. S., Oort, F. A., Van Turenhout, S. T., Larbi, I. B., Louwagie, J., Van Criekinge, W., Van Der Hulst, R. W. M., Mulder, C. J. J., Carvalho, B., Fijneman, R. J. A., Jimenez, C. R. & 1 others, Meijer, G. A., 19 Dec 2017, In : Annals of Internal Medicine. 167, 12, p. 855-866 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR

Verbrugge, C., Al, M., Assaraf, Y. G., Kammerer, S., Chandrupatla, D. M. S. H., Honeywell, R. J., Musters, R. P. J., Giovannetti, E., O'Toole, T., Scheffer, G. L., Krige, D., de Gruijl, T. D., Niessen, J., Lems, W. F., Kramer, P. A., Scheper, R. J., Cloos, J., Ossenkoppele, G. J., Peters, G. J. & Jansen, G., 2 Feb 2016, In : Oncotarget. 7, 5, p. 5240-5257

Research output: Contribution to journalArticleAcademicpeer-review

Sensing of latent EBV infection through exosomal transfer of 5'pppRNA

Baglio, S. R., van Eijndhoven, M. A. J., Koppers-Lalic, D., Berenguer, J., Lougheed, S. M., Gibbs, S., Leveille, N., Rinkel, R. N. P. M., Hopmans, E. S., Swaminathan, S., Verkuijlen, S. A. W. M., Scheffer, G. L., van Kuppeveld, F. J. M., de Gruijl, T. D., Bultink, I. E. M., Jordanova, E. S., Hackenberg, M., Piersma, S. R., Knol, J. C., Voskuyl, A. E. & 4 others, Wurdinger, T., Jimenez, C. R., Middeldorp, J. M. & Pegtel, D. M., 2 Feb 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 5, p. E587-E596

Research output: Contribution to journalArticleAcademicpeer-review

The in vitro mechanisms and in vivo efficacy of intravenous lidocaine on the neuroinflammatory response in acute and chronic pain

van der Wal, S. E. I., van den Heuvel, S. A. S., Radema, S. A., van Berkum, B. F. M., Vaneker, M., Steegers, M. A. H., Scheffer, G. J. & Vissers, K. C. P., May 2016, In : European Journal of Pain. 20, 5, p. 655-74 20 p.

Research output: Contribution to journalReview articleAcademicpeer-review