1983 …2019
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Research Output 1983 2019

1983

Destruction of murine lymphoma cells by allogeneic peritoneal macrophages in vitro: Influence of antiserum

Dingemans, K. P., Pels, E., Van Dongen, G. & Den Otter, W., 1 Jan 1983, In : Journal of the National Cancer Institute. 70, 1, p. 181-192 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

1984

Comparative studies on the heat-induced thermotolerance of protein synthesis and cell division in synchronized mouse neuroblastoma cells

Van Dongen, G., Van De Zande, L., Schamhart, D. & Van Wijk, R., 1 Jan 1984, In : International Journal of Radiation Biology. 46, 6, p. 759-769 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

1985

Cell Killing and Sensitization to Heat Shock by Hypothermic Incubation of Asynchronous and Synchronized Mouse Neuroblastoma Cells

van Dongen, G., Zoutewelle, G., van Rijn, J. & van Wijk, R., 1 Sep 1985, In : Cancer Research. 45, 9, p. 4132-4137 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Studies on a possible relationship between alterations in the cytoskeleton and induction of heat shock protein synthesis in mammalian cells

Van Bergen En Henegouwen, P. M. P., Jordi, W. J. R. M., Dongen, G. V., Ramaekers, F. C. S., Amesz, H. & Linnemans, W. A. M., 1 Jan 1985, In : International journal of hyperthermia. 1, 1, p. 69-83 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

1986

Effect of serum on heat response of synchronized mouse neuroblastoma cells: Protection of cell cycle progression, protein synthesis and survival

Van Dongen, G. & Van Wijk, R., 1 Jan 1986, In : International Journal of Radiation Biology. 50, 1, p. 77-91 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Increase of thermoresistance after growth stimulation of resting Reuber H35 hepatoma cells. Alteration of nuclear characteristics, non-histone chromosomal protein phosphorylation and basal heat shock protein synthesis

Van Dongen, G., Geilenkirchen, W. L. M., Van Rijn, J. & Van Wijk, R., 1 Jan 1986, In : Experimental Cell Research. 166, 2, p. 427-441 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

1987

Stress-induced Thermotolerance of the Cytoskeleton of Mouse Neuroblastoma N2A Cells and Rat Reuber H35 Hepatoma Cells

Wiegant, F. A. C., Van Bergen En Henegouwen, P. M. P., Van Dongen, G. & Linnemans, W. A. M., 15 Mar 1987, In : Cancer Research. 47, 6, p. 1674-1680 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1988

Evidence for a role of heat-shock proteins in proliferation after heat treatment of synchronized mouse neuroblastoma cells

Van Dongen, G. & Van Wijk, R., 1 Jan 1988, In : Radiation Research. 113, 2, p. 252-267 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Preclinical antitumor activity of 5-aza-2′-deoxycytidine agains human head and neck cancer xenografts

Braakhuis, B. J. M., van Dongen, G. A. M. S., van Walsum, M., Leyva, A. & Snow, G. B., 1 Dec 1988, In : Investigational New Drugs. 6, 4, p. 299-304 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

1989

Activity of the folate analog 10-ethyl, 10-deaza-aminopterin (10-EdAM) against human head and neck cancer xenografts

Brown, D. H., Braakhuis, B. J. M., Van Dongen, G. A. M. S., Van Walsum, M., Bagnay, M. & Snow, G. B., 1 Dec 1989, In : Anticancer Research. 9, 6, p. 1549-1552 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Anti‐tumor and differentiation‐inducing activity of n,n‐dimethylformamide (dmf) in head‐and‐neck cancer xenografts

Van Dongen, G. A. M. S., Braakhuis, B. J. M., Leyva, A., Hendriks, H. R., Kipp, B. B. A., Bagnay, M. & Snow, G. B., 1 Jan 1989, In : International Journal of Cancer. 43, 2, p. 285-292 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Preclinical chemotherapy on human head and neck cancer xenografts grown in athymic nude mice

Braakhuis, B. J. M., Van Dongen, G. A. M. S., Bagnay, M., Van Walsum, M. & Snow, G. B., 1 Jan 1989, In : Head & Neck. 11, 6, p. 511-515 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Transplantability of Human Head and Neck Squamous Cell Carcinomas in Athymic Nude Mice

Braakhuis, B. J. M., Laarman, D. A. W., Nauta, J. J. P., Van Walsum, M., Van Dongen, G. A. M. S. & Snow, G. B., 1 Jan 1989, In : Archives of Otolaryngology--Head and Neck Surgery. 115, 9, p. 1076-1078 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

1990

A 22-kd surface antigen detected by monoclonal antibody E 48 is exclusively expressed in stratified squamous and transitional epithelia

Quak, J. J., Balm, A. J. M., Van Dongen, G. A. M. S., Brakkee, J. G. P., Scheper, R. J., Snow, G. B. & Meijer, C. J. L. M., 1 Jan 1990, In : American Journal of Pathology. 136, 1, p. 191-197 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Antitumor activity of brequinar sodium (Dup-785) against human head and neck squanmous cell carcinoma xenografts

Braakhuis, B. J. M., van Dongen, G. A. M. S., Peters, G. J., van Walsum, M. & Snow, G. B., 1 Jan 1990, In : Cancer Letters. 49, 2, p. 133-137 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Comparative study of the sensitivity of head and neck cell lines to methotrexate (MTX) and the analog 10-ethyl, 10-deazaaminopterin (10-EdAM)

Brown, D. H., Braakhuis, B. J. M., Van Dongen, G. A. M. S. & Snow, G. B., 1 Jan 1990, In : Otolaryngology - Head and Neck Surgery. 102, 1, p. 20-25 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of a 43‐kda nuclear antigen associated with proliferation by monoclonal antibody k 112

Quak, J. J., Dongen, G. V., Koken, M. A. E., Brakkee, J. G. P., Scheper, R. J., Balm, A. J. M., Jong, L. D., Snow, G. B. & Meijer, C. J. L. M., 1 Jan 1990, In : International Journal of Cancer. 46, 1, p. 50-55 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Mechanisms underlying methotrexate inactivity in human head and neck cancer xenografts

Braakhuis, BJM., van Dongen, G., Snow, G. B., Peters, GJ., Leyva, A. & Jansen, G., 1990, In: "Chemistry and Biology of Pteridines". Curtius, H. C., Ghisla, S. & Blau, N. (eds.). Walter de Gruyter, p. 1119-1122 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

Production of a monoclonal antibody (K 931) to a squamous cell carcinoma associated antigen identified as the 17-1A antigen

Quak, J. J., Van Dongen, G., Brakkee, J. G. P., Hayashida, D. J., Balm, A. J. M., Snow, G. B. & Meijer, C. J. L. M., 1 Jan 1990, In : Hybridoma. 9, 4, p. 377-387 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

1991

Detection of Squamous Cell Carcinoma Xenografts in Nude Mice by Radiolabeled Monoclonal Antibody E48

Quak, J. J., Gerretsen, M., Schrijvers, A. H. G. J., Meijer, C. J. L. M., Van Dongen, G. A. M. S. & Snow, G. B., 1 Jan 1991, In : Archives of Otolaryngology--Head and Neck Surgery. 117, 11, p. 1287-1291 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Evidence for a role of the monoclonal antibody E48 defined antigen in cell-cell adhesion in squamous epithelia and head and neck squamous cell carcinoma

Schrijvers, A. H. G. J., Gerretsen, M., Fritz, J. M., van Walsum, M., Quak, J. J., Snow, G. B. & van Dongen, G. A. M. S., 1 Jan 1991, In : Experimental Cell Research. 196, 2, p. 264-269 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Preclinical in Vivo Activity of 2',2'-Difluorodeoxycytidine (Gemcitabine) against Human Head and Neck Cancer

Braakhuis, B. J. M., van Dongen, G. A. M. S. & Snow, G. B., 1 Jan 1991, In : Cancer Research. 51, 1, p. 211-214 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

1992

Expression and characterization of two differentiation antigens in human stratified squamous epithelia and carcinomas

Quak, J. J., Schrijvers, A. H. G. J., Brakkee, J. G. P., Davis, H. D., Scheper, R. J., Meijer, C. J. L. M., Snow, G. B. & van Donoen, G. A. M. S., 1 Jan 1992, In : International Journal of Cancer. 50, 4, p. 507-513 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Growth of xenografted squamous cell carcinoma of the head and neck ‐ possible correlation with patient survival

ZÄTTERSTRÖM, U. K., BRAAKHUIS, B. J. M., WENNERBERG, J., VAN DONGEN, G. A. M. S., ATTEWELL, R., NAUTA, J. J. P., LAARMAN, D. A. W. & ASK, A., 1 Jan 1992, In : APMIS. 100, 7-12, p. 976-980 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Potential for targeting head and neck squamous cell carcinoma with monoclonal antibody K984

Schrijvers, A. H. G. J., Gerretsen, M., van Walsum, M., Braakhuis, B. J. M., Quak, J. J., Snow, G. B. & van Dongen, G. A. M. S., 1 Jul 1992, In : Cancer Immunology Immunotherapy. 34, 4, p. 252-258 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Radioimmunoscintigraphy of Head and Neck Cancer Using 99mTc-labeled Monoclonal Antibody E48 F(ab')2

van Dongen, G. A. M. S., Leverstein, H., Quak, J. J., van den Brekel, M. W. M. & Snow, G. B., 1 Jan 1992, In : Cancer Research. 52, 9, p. 2569-2574 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Radioimmunotherapy of human head and neck squamous cell carcinoma xenografts with131i-labelled monoclonal antibody e48 igg

Gerretsen, M., Schrijvers, A. H. G. J., Van Walsum, M., Braakhuis, B. J. M., Quak, J. J., Meijer, C., Snow, G. B. & Van Dongen, G. A. M. S., 1 Jan 1992, In : British Journal of Cancer. 66, 3, p. 496-502 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1993

186Re-labeled Monoclonal Antibody E48 Immunoglobulin G-mediated Therapy of Human Head and Neck Squamous Cell Carcinoma Xenografts

Gerretsen, M., Walsum, M. V., Snow, G. B. & van Dongen, G. A. M. S., 1 Jan 1993, In : Cancer Research. 53, 15, p. 3524-3529 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

A panel of biomarkers of carcinogenesis of the upper aerodigestive tract as potential intermediate endpoints in chemoprevention trials

Copper, M. P., Braakhuis, B. J. M., de Vries, N., Van Dongen, G. A. M. S., Nauta, J. J. P. & Snow, G. B., 1 Jan 1993, In : Cancer. 71, 3, p. 825-830 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Labeling of monoclonal antibodies with rhenium-186 using the MAG3 chelate for radioimmunotherapy of cancer: A technical protocol

Visser, G. W. M., Gerretsen, M., Herscheid, J. D. M., Snow, G. B. & Van Dongen, G., 1 Jan 1993, In : Journal of Nuclear Medicine. 34, 11, p. 1953-1963 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

MAb U36, a Novel Monoclonal Antibody Successful in Immunotargeting of Squamous Cell Carcinoma of the Head and Neck

Schryvers, A. H. G. J., Quak, J. J., Walsum, M. V., Snow, G. B. & van Dongen, G. A. M. S., 1 Jan 1993, In : Cancer Research. 53, 18, p. 4383-4390 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Perspectives of monoclonal antibodies for detection and treatment of head and neck tumours

Quak, J., Gerretsen, M., De Bree, R., Brakenhof, R., Van Dongen, G. & Snow, G., 1 Dec 1993, In : Anticancer Research. 13, 6 B, p. 2533-2539 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1994

Clinical imaging of head and neck cancer with technetium-99m-labeled monoclonal antibody E48 IgG or F(ab')2

De Bree, R., Roos, J. C., Quak, J. J., Den Hollander, W., Van den Brekel, M. W. M., Van der Wal, J. E., Tobi, H., Snow, G. B. & Van Dongen, G. A. M. S., 1 Jan 1994, In : Journal of Nuclear Medicine. 35, 5, p. 775-783 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Clinical screening of monoclonal antibodies 323/A3, cSF-25 and K928 for suitability of targetting tumours in the upper aerodigestive and respiratory tract

De Bree, R., Roos, J. C., Quak, J. J., Hollander, W. D., Snow, G. B. & Van Dongen, G., 1 Jan 1994, In : Nuclear Medicine Communications. 15, 8, p. 613-627 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Complete ablation of small squamous cell carcinoma xenografts with186Re-labeled monoclonal antibody E48

Gerretsen, M., Visser, G. W. M., Brakenhoff, R. H., van Walsum, M., Snow, G. B. & van Dongen, G. A. M. S., 1 Jan 1994, In : Cell Biophysics. 24-25, 1-3, p. 135-142 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Current perspectives in the use of monoclonal antibodies for detection and treatment of head and neck tumors

Quak, J. & van Dongen, G., 1 Aug 1994, In : European Archives of Oto-Rhino-Laryngology. 251, 1, p. 1-5 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Monoclonal antibodies for diagnosis and therapy of squamous cell carcinoma of the head and neck.

Gripp, F. M., Quak, J., Leverstein, H., Schrijvers, A., Gerretsen, M., Brakenhoff, R., Van Dongen, G., Snow, G. B. & Rapoport, A., 1 Jul 1994, In : Revista Paulista de Medicina. 112, 3, p. 612-621 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Optimization and simplification of expression cloning in eukaryotic vector/host systems

Brakenhoff, R. H., Knippels, E. M. C. & van dongen, G. A. M. S., 1 May 1994, In : Analytical Biochemistry. 218, 2, p. 460-463 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Progress in radioimmunotherapy of head and neck cancer (review)

Van Dongen, G. A. M. S., Brakenhoff, R. H., De Bree, R., Gerretsen, M., Quak, J. J. & Snow, G. B., 1 Jan 1994, In : Oncology Reports. 1, 1, p. 259-264 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

The feasibility of radioimmunotherapy of head and neck cancer

Gerretsen, M., Quak, J. J., Brakenhoff, R. H., Snow, G. B. & van Dongen, G. A. M. S., 1 Jan 1994, In : European Journal of Cancer. Part B: Oral Oncology. 30, 2, p. 82-87 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

1995

Biodistribution of Radiolabeled Monoclonal Antibody E48 Igg and F(Ab')2 in Patients with Head and Neck Cancer

Bree, R. D., Roos, J. C., Quak, J. J., Hollander, W. D., Wilhelm, A. J., Lingen, A. V., Snow, G. B. & Van Dongen, G. A. M. S., 1 Mar 1995, In : Clinical Cancer Research. 1, 3, p. 277-286 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Construction and characterization of the chimeric monoclonal antibody E48 for therapy of head and neck cancer

Brakenhoff, R. H., van Gog, F. B., Looney, J. E., van Walsum, M., Snow, G. B. & van Dongen, G. A. M. S., 1 May 1995, In : Cancer Immunology Immunotherapy. 40, 3, p. 191-200 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Natural killer (NK) cells as effectors of antibody‐dependent cytotoxicity with chimeric antibodies reactive with human squamous‐cell carcinomas of the head and neck

Sung, MW. W., Yasumura, S., Johnson, J. T., Van Dongen, G. A. M. S. & Whitesidi, T. L., 1 Jan 1995, In : International Journal of Cancer. 61, 6, p. 864-872 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Radioimmunoscintigraphy and Biodistribution of Technetium-99m-Labeled Monoclonal Antibody U36 in Patients with Head and Neck Cancer

Bree, R. D., Roos, J. C., Quak, J. J., Hollander, W. D., Snow, G. B. & van Dongen, G. A. M. S., 1 Jun 1995, In : Clinical Cancer Research. 1, 6, p. 591-598 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion

Brakenhoff, R. H., Gerretsen, M., Knippels, E. M. C., Van Dijk, M., Van Essen, H., Weghuis, D. O., Sinke, R. J., Snow, G. B. & Van Dongen, G. A. M. S., 1 Jun 1995, In : Journal of Cell Biology. 129, 6, p. 1677-1689 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

1996

Monoclonal antibodies labeled with rhenium-186 using the MAG3 chelate: Relationship between the number of chelated groups and biodistribution characteristics

Van Gog, F. B., Visser, G. W. M., Klok, R., Van Der Schors, R., Snow, G. B. & Van Dongen, G. A. M. S., 1 Feb 1996, In : Journal of Nuclear Medicine. 37, 2, p. 352-362 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Monoclonal antibody U36, a suitable candidate for clinical immunotherapy of squamous-cell carcinoma, recognizes a CD44 isoform

Van Hal, N. L. W., Van Dongen, G. A. M. S., Rood-Knippels, E. M. C., Van der Valk, P., Snow, G. B. & Brakenhoff, R. H., 21 Dec 1996, In : International Journal of Cancer. 68, 4, p. 520-527 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Protective effects of interferon-γ on squamous-cell carcinoma of head and neck targets in antibody-dependent cellular cytotoxicity mediated by human natural killer cells

Sung, M. W., Johnson, J. T., Van Dongen, G. & Whiteside, T. L., 3 May 1996, In : International Journal of Cancer. 66, 3, p. 393-399 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Squamous cell carcinoma-associated antigens used in novel strategies for the detection and treatment of minimal residual head and neck cancer

Van Dongen, G. A. M. S., Brakenhoff, R. M., Ten Brink, C., Van Gog, F. B., De Bree, R., Ouak, J. J. & Snow, G. B., 1 Jul 1996, In : Anticancer Research. 16, 4 C, p. 2409-2413 5 p.

Research output: Contribution to journalArticleAcademicpeer-review