1983 …2019
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Research Output 1983 2019

2014

Development of [F-18]afatinib as new TKI-PET tracer for EGFR positive tumors

Slobbe, P., Windhorst, A. D., Stigter-van Walsum, M., Schuit, R. C., Smit, E. F., Niessen, H. G., Solca, F., Stehle, G., van Dongen, G. A. M. S. & Poot, A. J., 2014, In : Nuclear Medicine and Biology. 41, 9, p. 749-757

Research output: Contribution to journalArticleAcademicpeer-review

Development of Novel ADCs: Conjugation of Tubulysin Analogues to Trastuzumab Monitored by Dual Radiolabeling

Cohen, R., Vugts, D. J., Visser, G. W. M., Stigter-van Walsum, M., Bolijn, M., Spiga, M., Lazzari, P., Shankar, S., Sani, M., Zanda, M. & van Dongen, G. A. M. S., 2014, In : Cancer Research. 74, 20, p. 5700-5710

Research output: Contribution to journalArticleAcademicpeer-review

Multicenter Harmonization of Zr-89 PET/CT Performance

Makris, N., Boellaard, R., Visser, E. P., de Jong, J. R., Vanderlinden, B., Wierts, R., van der Veen, B. J., Greuter, H. J. N. M., Vugts, D. J., van Dongen, G. A. M. S., Lammertsma, A. A. & Huisman, M. C., 2014, In : Journal of Nuclear Medicine. 55, 2, p. 264-267

Research output: Contribution to journalArticleAcademicpeer-review

20 Downloads (Pure)

Novel molecular imaging approaches in the management of head and neck cancer

Heuveling, D. A., 2014

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

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Pharmacokinetics, Brain Delivery, and Efficacy in Brain Tumor-Bearing Mice of Glutathione Pegylated Liposomal Doxorubicin (2B3-101)

Gaillard, P. J., Appeldoorn, C. C. M., van Dorland, R., van Kregten, J., Manca, F., Vugts, D. J., Windhorst, A. D., van Dongen, G. A. M. S., de Vries, H. E., Maussang, D. & van Tellingen, O., 2014, In : PLoS ONE. 9, 1, e82331.

Research output: Contribution to journalArticleAcademicpeer-review

Preclinical evaluation of Zr-89-labeled anti-CD44 monoclonal antibody RG7356 in mice and cynomolgus monkeys Prelude to Phase 1 clinical studies

Vugts, D. J., Heuveling, D. A., Stigter-van Walsum, M., Weigand, S., Bergstrom, M., van Dongen, G. A. M. S. & Nayak, T. K., 2014, In : MABS. 6, 2, p. 567-575

Research output: Contribution to journalArticleAcademicpeer-review

Sentinel node biopsy in patients with early oral cancer. New developments

de Bree, R., Heuveling, D. A., van Dongen, G. A. M. S. & Hoekstra, O. S., 2014, In : Hellenic Surgical Oncology. 5, p. 9-15

Research output: Contribution to journalArticleAcademic

Three-Dimensional Histologic Validation of High-Resolution SPECT of Antibody Distributions Within Xenografts

Branderhorst, W., Blezer, E. L. A., Houtkamp, M., Ramakers, R. M., van den Brakel, J. H., Witteveen, H., van der Have, F., van Andel, H. A. G., Vastenhouw, B., Wu, C., Stigter-van Walsum, M., van Dongen, G. A. M. S., Viergever, M. A., Bleeker, W. K. & Beekman, F. J., 2014, In : Journal of Nuclear Medicine. 55, 5, p. 830-837

Research output: Contribution to journalArticleAcademicpeer-review

2013

[C-11]Sorafenib: Radiosynthesis and preclinical evaluation in tumor-bearing mice of a new TKI-PET tracer

Poot, A. J., van der Wildt, B., Stigter-van Walsum, M., Rongen, M., Schuit, R. C., Hendrikse, N. H., Eriksson, P. A. J., van Dongen, G. A. M. S. & Windhorst, A. D., 2013, In : Nuclear Medicine and Biology. 40, 4, p. 488-497

Research output: Contribution to journalArticleAcademicpeer-review

EATRIS, a European initiative to boost translational biomedical research

van Dongen, G. A. M. S., Ussi, A. E., De Man, F. H. & Migliaccio, G., 2013, In : American journal of nuclear medicine and molecular imaging. 3, 2, p. 166-174

Research output: Contribution to journalArticleAcademicpeer-review

39 Downloads (Pure)

Hematopoietic stem cell transplantation in B- and T-cell lymphoma

Visser, O., 2013

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

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Imaging of TKI-Target Interactions for Personalized Cancer Therapy

Poot, A. J., Slobbe, P., Hendrikse, N. H., Windhorst, A. D. & van Dongen, G. A. M. S., 2013, In : Clinical Pharmacology & Therapeutics. 93, 3, p. 239-241

Research output: Contribution to journalArticleAcademicpeer-review

ImmunoPET Imaging of Renal Cell Carcinoma with I-124- and Zr-89-Labeled Anti-CAIX Monoclonal Antibody cG250 in Mice

Stillebroer, A. B., Franssen, G. M., Mulders, P. F. A., Oyen, W. J. G., van Dongen, G. A. M. S., Laverman, P., Oosterwijk, E. & Boerman, OC., 2013, In : Cancer Biotherapy and Radiopharmaceuticals. 28, 7, p. 510-515

Research output: Contribution to journalArticleAcademicpeer-review

Inert coupling of IRDye800CW and zirconium-89 to monoclonal antibodies for single- or dual-mode fluorescence and PET imaging

Cohen, R., Vugts, D. J., Stigter-van Walsum, M., Visser, G. W. M. & van Dongen, G. A. M. S., 2013, In : Nature Protocols. 8, 5, p. 1010-1018

Research output: Contribution to journalArticleAcademicpeer-review

Llama-derived single variable domains (Nanobodies) directed against CXCR7 reduce head and neck cancer cell growth in vivo

Maussang, D., Mujic-Delic, A., Descamps, F. J., Stortelers, C., Stigter-van Walsum, M., Vischer, H. F., van Roy, M., Vosjan, M. J. W. D., Gonzalez-Pajuelo, M., van Dongen, G. A., Merchiers, P., van Rompaey, P. & Smit, M. J., 2013, In : Journal of Biological Chemistry. 288, 41, p. 29562-29572

Research output: Contribution to journalArticleAcademicpeer-review

PET-beeldvorming in geneesmiddelenontwikkeling en toepassing

van Dongen, G. A. M. S., Hoekstra, O. S., Lammertsma, A. A., Vugts, D. J., Hendrikse, N. H. & Windhorst, A. D., 2013, In : Nederlands Tijdschrift voor Oncologie. 10, 175, p. 182

Research output: Contribution to journalArticleProfessional

Phase 0 Microdosing PET Study Using the Human Mini Antibody F16SIP in Head and Neck Cancer Patients

Heuveling, D. A., de Bree, R., Vugts, D. J., Huisman, M. C., Giovannoni, L., Hoekstra, O. S., Leemans, C. R., Neri, D. & van Dongen, G. A. M. S., 2013, In : Journal of Nuclear Medicine. 54, 3, p. 397-401

Research output: Contribution to journalArticleAcademicpeer-review

2012
27 Downloads (Pure)

A novel method to quantify IRDye800CW fluorescent antibody probes ex vivo in tissue distribution studies

Oliveira, S., Cohen, R., Walsum, M. S., van Dongen, G. A. M. S., Elias, S. G., van Diest, P. J., Mali, W. & van Bergen en Henegouwen, P. M., 2012, In : EJNMMI Research. 2, 1, p. 50 50.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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36 Downloads (Pure)

Iodine-123 and Fluorine-18 radiolabeled analogues of WAY-100635 as potential radioligands for imaging the 5-HT1A receptor in the brain

al Hussainy, R., 2012

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File

Nanobodies Targeting the Hepatocyte Growth Factor: Potential New Drugs for Molecular Cancer Therapy

Vosjan, M. J. W. D., Vercammen, J., Kolkman, J. A., Stigter-van Walsum, M., Revets, H. & van Dongen, G. A. M. S., 2012, In : Molecular Cancer Therapeutics. 11, 4, p. 1017-1025

Research output: Contribution to journalArticleAcademicpeer-review

47 Downloads (Pure)

Nanobody constructs, targeting growth factors and their receptors, for PET imaging and cancer therapy

Vosjan, M. J. W. D., 2012

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File

Nanocolloidal albumin-IRDye 800CW: a near-infrared fluorescent tracer with optimal retention in the sentinel lymph node

Heuveling, D. A., Visser, G. W. M., de Groot, M., de Boer, J. F., Salumbides - Baclayon, M., Roos, W. H., Wuite, G. J. L., Leemans, C. R., de Bree, R. & van Dongen, G. A. M. S., 2012, In : European Journal of Nuclear Medicine and Molecular Imaging. 39, 7, p. 1161-1168 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Nb-90 - a potential PET nuclide: production and labeling of monoclonal antibodies

Radchenko, V., Hauser, H., Eisenhut, M., Vugts, D. J., van Dongen, G. A. M. S. & Roesch, F., 2012, In : Radiochimica acta. 100, 11, p. 857-863

Research output: Contribution to journalArticleAcademicpeer-review

PET imaging with radiolabeled antibodies and tyrosine kinase inhibitors: immuno-PET and TKI-PET

van Dongen, G. A. M. S., Poot, A. J. & Vugts, D. J., 2012, In : Tumor Biology. 33, 3, p. 607-615

Research output: Contribution to journalArticleAcademicpeer-review

PET imaging with small-molecule tyrosine kinase inhibitors: TKI-PET

Slobbe, P., Poot, A. J., Windhorst, A. D. & van Dongen, G. A. M. S., 2012, In : Drug Discovery Today. 17, 21-22, p. 1175-1187

Research output: Contribution to journalArticleAcademicpeer-review

Positronemissietomografie van [ 89Zr]trastuzumab bij patiënten met gemetastaseerde HER2-positieve borstkanker

Dijkers, E. C. F., Munnink, T. H. O., De Vries, E. G. E., Brouwers, A. H., Jager, P. L., De Jong, J. R., Van Dongen, G. A. M. S., Schröder, C. P., Lub-De Hooge, M. N. & Kosterink, J. G. W., 20 Apr 2012, In : Pharmaceutisch Weekblad. 147, 16, p. 62-67 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Public-private partnerships in translational medicine: Concepts and practical examples

Luijten, P. R., van Dongen, G. A. M. S., Moonen, C. T., Storm, G. & Crommelin, D. J. A., 2012, In : Journal of Controlled Release. 161, 2, p. 416-421

Research output: Contribution to journalArticleAcademicpeer-review

Rapid Visualization of Human Tumor Xenografts through Optical Imaging with a Near-infrared Fluorescent Anti-Epidermal Growth Factor Receptor Nanobody

Oliveira, S., van Dongen, G. A. M. S., Stigter-van Walsum, M., Roovers, R. C., Stam, J. C., Mali, W., van Diest, P. J. & van Bergen en Henegouwen, P. M., 2012, In : Molecular Imaging. 11, 1, p. 33-46

Research output: Contribution to journalArticleAcademicpeer-review

29 Downloads (Pure)

Safety and Efficacy of Radioimmunotherapy with 90Yttrium-rituximab in Patients with Relapsed CD20+ B cell Lymphoma: A Feasibility Study

Vaes, M., Bron, D., Vugts, D. J., Paesmans, M., Meuleman, M., Ghanem, G., Guiot, T., Vanderlinden, B., Thielemans, K., van Dongen, G. A. M. S., Flamen, P. & Muylle, K., 2012, In : Journal of Cancer Science & Therapy. 4, 12, p. 394-400

Research output: Contribution to journalArticleAcademic

Open Access
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2011

(89)Zr-Nanocolloidal Albumin-Based PET/CT Lymphoscintigraphy for Sentinel Node Detection in Head and Neck Cancer: Preclinical Results

Heuveling, D. A., Visser, G. W. M., Salumbides - Baclayon, M., Roos, W. H., Wuite, G. J. L., Hoekstra, O. S., Leemans, C. R., de Bree, R. & van Dongen, G. A. M. S., 2011, In : Journal of Nuclear Medicine. 52, 10, p. 1580-1584 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

89Zr-labeled compounds for PET imaging guided personalized therapy

Vugts, D. J. & Van Dongen, G. A. M. S., 1 Jan 2011, In : Drug Discovery Today: Technologies. 8, 2-4

Research output: Contribution to journalReview articleAcademicpeer-review

A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth

Roovers, R. C., Vosjan, M. J. W. D., Laeremans, T., el Khoulati, R., de Bruin, R. C. G., Ferguson, K. M., Verkleij, A. J., van Dongen, G. A. M. S. & Henegouwen, P. M. P. V., 2011, In : International Journal of Cancer. 129, 8, p. 2013-2024

Research output: Contribution to journalArticleAcademicpeer-review

27 Downloads (Pure)

EATRIS, a Vision for Translational Research in Europe

Becker, R. & van Dongen, G. A. M. S., 2011, In : Journal of Cardiovascular Translational Research. 4, 3, p. 231-237

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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26 Downloads (Pure)

Facile labelling of an anti-epidermal growth factor receptor Nanobody with (68)Ga via a novel bifunctional desferal chelate for immuno-PET

Vosjan, M. J. W. D., Perk, L. R., Roovers, R. C., Visser, G. W. M., Stigter-van Walsum, M., Henegouwen, P. M. P. V. & van Dongen, G. A. M. S., 2011, In : European Journal of Nuclear Medicine and Molecular Imaging. 38, 4, p. 753-763

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
32 Downloads (Pure)

Inert coupling of IRDye800CW to monoclonal antibodies for clinical optical imaging of tumor targets

Cohen, R., Stammes, M. A., de Roos, I. H. C., Stigter-van Walsum, M., Visser, G. W. M. & van Dongen, G. A. M. S., 2011, In : EJNMMI Research. 1, 1, p. 31

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Preclinical evaluation and validation of [(18)F]HX4, a promising hypoxia marker for PET imaging

Dubois, L. J., Lieuwes, N. G., Janssen, M. H. M., Peeters, W. J. M., Windhorst, A. D., Walsh, J. C., Kolb, H. C., Ollers, M. C., Bussink, J., van Dongen, G. A. M. S., van der Kogel, A. & Lambin, P., 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 35, p. 14620-14625

Research output: Contribution to journalArticleAcademicpeer-review

Radioactieve labeling van monoklonale antilichamen en de mogelijkheden van nucleaire beeldvorming

van Dongen, G. A. M. S., 2011, In : Angiogenese Journaal. 1, p. 13-15

Research output: Contribution to journalArticleProfessional

Synthesis of Phosphine and Antibody-Azide Probes for in Vivo Staudinger Ligation in a Pretargeted Imaging and Therapy Approach

Vugts, D. J., Vervoort, A., Stigter-van Walsum, M., Visser, G. W. M., Robillard, M. S., Versteegen, R. M., Vulders, R. C. M., Herscheid, J. D. M. & van Dongen, G. A. M. S., 2011, In : Bioconjugate chemistry. 22, 10, p. 2072-2081

Research output: Contribution to journalArticleAcademicpeer-review

The potential role of non-FDG-PET in the management of head and neck cancer

Heuveling, D. A., de Bree, R. & van Dongen, G. A. M. S., 2011, In : Oral Oncology. 47, 1, p. 2-7

Research output: Contribution to journalArticleAcademicpeer-review

2010

89Zr-bevacizumab PET of early antiangiogenic tumor response to treatment with HSP90 inhibitor NVP-AUY922.

Nagengast, W. B., de Korte, M. A., Oude Munnink, T. H., Timmer-Bosscha, H., den Dunnen, W. F., Hollema, H., de Jong, J. R., Jensen, M. R., Quadt, C., Garcia-Echeverria, C., van Dongen, G. A. M. S., Lub-de Hooge, M. N., Schröder, C. P. & de Vries, E. G. E., 1 May 2010, In : Journal of Nuclear Medicine. 51, 5, p. 761-767 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biodistribution and Radiation Dosimetry of 90Y-Ibritumomab-Tiuxetan Using 89Zr-Ibritumomab-Tiuxetan and Immuno-Pet in Patients with B-Cell Nhl

Visser, O., Rizvi, S. N. F., Wondergem, M. J., van Lingen, A., van Dongen, G. A. M. S., Hoekstra, O. S., Zijlstra-Baalbergen, J. M., Huijgens, P. C. & Lubberink, J. M., 2010, In : Haematologica. 95, p. 1609

Research output: Contribution to journalMeeting AbstractOther research output

Biodistribution of Zr-89-trastuzumab and PET Imaging of HER2-Positive Lesions in Patients With Metastatic Breast Cancer

Dijkers, E. C., Munnink, T. H. O., Kosterink, J. G., Brouwers, A. H., de Jager, P. L., de Jong, J. R., van Dongen, G. A. M. S., Schroder, C. P., Lub-de Hooge, M. N. & de Vries, E. G. E., 2010, In : Clinical Pharmacology & Therapeutics. 87, 5, p. 586-592

Research output: Contribution to journalArticleAcademicpeer-review

Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine

Vosjan, M. J. W. D., Perk, L. R., Visser, G. W. M., Budde, M., Jurek, P., Kiefer, G. E. & van Dongen, G. A. M. S., 2010, In : Nature Protocols. 5, 4, p. 739-743

Research output: Contribution to journalArticleAcademicpeer-review

Immuno-Positron Emission Tomography: Shedding Light on Clinical Antibody Therapy

van Dongen, G. A. M. S. & Vosjan, M. J. W. D., 2010, In : Cancer Biotherapy and Radiopharmaceuticals. 25, 4, p. 375-385

Research output: Contribution to journalArticleAcademicpeer-review

Molecular imaging for visualization and quantification of individualized targeted cancer therapy

Lubberink, M., Rizvi, S. N. F., Hoekstra, O. S. & van Dongen, G. A. M. S., 11 Nov 2010, In : MedicaMundi. 54, 2, p. 47-54 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

26 Downloads (Pure)

PET imaging of hypoxia using [F-18]HX4: a phase I trial

van Loon, J., Janssen, M. H. M., Ollers, M. C., Aerts, H. J. W. L., Dubois, L., Hochstenbag, M., Dingemans, A. M. C., Lalisang, R., Brans, B., Windhorst, A. D., van Dongen, G. A. M. S., Kolb, H., Zhang, J., De Ruysscher, D. & Lambin, P., 2010, In : European Journal of Nuclear Medicine and Molecular Imaging. 37, 9, p. 1663-1668

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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