Research Output per year
Research Output 1983 2019
- 50 - 100 out of 202 results
- Publication Year, Title (descending)
2014
Three-Dimensional Histologic Validation of High-Resolution SPECT of Antibody Distributions Within Xenografts
Branderhorst, W., Blezer, E. L. A., Houtkamp, M., Ramakers, R. M., van den Brakel, J. H., Witteveen, H., van der Have, F., van Andel, H. A. G., Vastenhouw, B., Wu, C., Stigter-van Walsum, M., van Dongen, G. A. M. S., Viergever, M. A., Bleeker, W. K. & Beekman, F. J., 2014, In : Journal of Nuclear Medicine. 55, 5, p. 830-837Research output: Contribution to journal › Article › Academic › peer-review
2013
[C-11]Sorafenib: Radiosynthesis and preclinical evaluation in tumor-bearing mice of a new TKI-PET tracer
Poot, A. J., van der Wildt, B., Stigter-van Walsum, M., Rongen, M., Schuit, R. C., Hendrikse, N. H., Eriksson, P. A. J., van Dongen, G. A. M. S. & Windhorst, A. D., 2013, In : Nuclear Medicine and Biology. 40, 4, p. 488-497Research output: Contribution to journal › Article › Academic › peer-review
EATRIS, a European initiative to boost translational biomedical research
van Dongen, G. A. M. S., Ussi, A. E., De Man, F. H. & Migliaccio, G., 2013, In : American journal of nuclear medicine and molecular imaging. 3, 2, p. 166-174Research output: Contribution to journal › Article › Academic › peer-review
Imaging of TKI-Target Interactions for Personalized Cancer Therapy
Poot, A. J., Slobbe, P., Hendrikse, N. H., Windhorst, A. D. & van Dongen, G. A. M. S., 2013, In : Clinical Pharmacology & Therapeutics. 93, 3, p. 239-241Research output: Contribution to journal › Article › Academic › peer-review
ImmunoPET Imaging of Renal Cell Carcinoma with I-124- and Zr-89-Labeled Anti-CAIX Monoclonal Antibody cG250 in Mice
Stillebroer, A. B., Franssen, G. M., Mulders, P. F. A., Oyen, W. J. G., van Dongen, G. A. M. S., Laverman, P., Oosterwijk, E. & Boerman, OC., 2013, In : Cancer Biotherapy and Radiopharmaceuticals. 28, 7, p. 510-515Research output: Contribution to journal › Article › Academic › peer-review
Inert coupling of IRDye800CW and zirconium-89 to monoclonal antibodies for single- or dual-mode fluorescence and PET imaging
Cohen, R., Vugts, D. J., Stigter-van Walsum, M., Visser, G. W. M. & van Dongen, G. A. M. S., 2013, In : Nature Protocols. 8, 5, p. 1010-1018Research output: Contribution to journal › Article › Academic › peer-review
Llama-derived single variable domains (Nanobodies) directed against CXCR7 reduce head and neck cancer cell growth in vivo
Maussang, D., Mujic-Delic, A., Descamps, F. J., Stortelers, C., Stigter-van Walsum, M., Vischer, H. F., van Roy, M., Vosjan, M. J. W. D., Gonzalez-Pajuelo, M., van Dongen, G. A., Merchiers, P., van Rompaey, P. & Smit, M. J., 2013, In : Journal of Biological Chemistry. 288, 41, p. 29562-29572Research output: Contribution to journal › Article › Academic › peer-review
PET-beeldvorming in geneesmiddelenontwikkeling en toepassing
van Dongen, G. A. M. S., Hoekstra, O. S., Lammertsma, A. A., Vugts, D. J., Hendrikse, N. H. & Windhorst, A. D., 2013, In : Nederlands Tijdschrift voor Oncologie. 10, 175, p. 182Research output: Contribution to journal › Article › Professional
Phase 0 Microdosing PET Study Using the Human Mini Antibody F16SIP in Head and Neck Cancer Patients
Heuveling, D. A., de Bree, R., Vugts, D. J., Huisman, M. C., Giovannoni, L., Hoekstra, O. S., Leemans, C. R., Neri, D. & van Dongen, G. A. M. S., 2013, In : Journal of Nuclear Medicine. 54, 3, p. 397-401Research output: Contribution to journal › Article › Academic › peer-review
Pilot Study on the Feasibility of PET/CT Lymphoscintigraphy with Zr-89-Nanocolloidal Albumin for Sentinel Node Identification in Oral Cancer Patients
Heuveling, D. A., van Schie, A., Vugts, D. J., Hendrikse, N. H., Yaqub, M. M., Hoekstra, O. S., Karagozoglu, K. H., Leemans, C. R., van Dongen, G. A. M. S. & de Bree, R., 2013, In : Journal of Nuclear Medicine. 54, 4, p. 585-589Research output: Contribution to journal › Article › Academic › peer-review
Zr-89-PET Radiochemistry in the Development and Application of Therapeutic Monoclonal Antibodies and Other Biologicals
Vugts, D. J., Visser, G. W. M. & van Dongen, G. A. M. S., 2013, In : Current Topics in Medicinal Chemistry. 13, 4, p. 446-457Research output: Contribution to journal › Article › Academic › peer-review
2012
A novel method to quantify IRDye800CW fluorescent antibody probes ex vivo in tissue distribution studies
Oliveira, S., Cohen, R., Walsum, M. S., van Dongen, G. A. M. S., Elias, S. G., van Diest, P. J., Mali, W. & van Bergen en Henegouwen, P. M., 2012, In : EJNMMI Research. 2, 1, p. 50 50.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
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Biodistribution, radiation dosimetry and scouting of Y-90-ibritumomab tiuxetan therapy in patients with relapsed B-cell non-Hodgkin's lymphoma using Zr-89-ibritumomab tiuxetan and PET
Rizvi, S. N. F., Visser, O., Vosjan, M. J. W. D., van Lingen, A., Hoekstra, O. S., Zijlstra-Baalbergen, J. M., Huijgens, P. C., van Dongen, G. A. M. S. & Lubberink, J. M., 2012, In : European Journal of Nuclear Medicine and Molecular Imaging. 39, 3, p. 512-520Research output: Contribution to journal › Article › Academic › peer-review
Nanobodies Targeting the Hepatocyte Growth Factor: Potential New Drugs for Molecular Cancer Therapy
Vosjan, M. J. W. D., Vercammen, J., Kolkman, J. A., Stigter-van Walsum, M., Revets, H. & van Dongen, G. A. M. S., 2012, In : Molecular Cancer Therapeutics. 11, 4, p. 1017-1025Research output: Contribution to journal › Article › Academic › peer-review
Nanocolloidal albumin-IRDye 800CW: a near-infrared fluorescent tracer with optimal retention in the sentinel lymph node
Heuveling, D. A., Visser, G. W. M., de Groot, M., de Boer, J. F., Salumbides - Baclayon, M., Roos, W. H., Wuite, G. J. L., Leemans, C. R., de Bree, R. & van Dongen, G. A. M. S., 2012, In : European Journal of Nuclear Medicine and Molecular Imaging. 39, 7, p. 1161-1168 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Nb-90 - a potential PET nuclide: production and labeling of monoclonal antibodies
Radchenko, V., Hauser, H., Eisenhut, M., Vugts, D. J., van Dongen, G. A. M. S. & Roesch, F., 2012, In : Radiochimica acta. 100, 11, p. 857-863Research output: Contribution to journal › Article › Academic › peer-review
PET imaging with radiolabeled antibodies and tyrosine kinase inhibitors: immuno-PET and TKI-PET
van Dongen, G. A. M. S., Poot, A. J. & Vugts, D. J., 2012, In : Tumor Biology. 33, 3, p. 607-615Research output: Contribution to journal › Article › Academic › peer-review
PET imaging with small-molecule tyrosine kinase inhibitors: TKI-PET
Slobbe, P., Poot, A. J., Windhorst, A. D. & van Dongen, G. A. M. S., 2012, In : Drug Discovery Today. 17, 21-22, p. 1175-1187Research output: Contribution to journal › Article › Academic › peer-review
Positronemissietomografie van [ 89Zr]trastuzumab bij patiënten met gemetastaseerde HER2-positieve borstkanker
Dijkers, E. C. F., Munnink, T. H. O., De Vries, E. G. E., Brouwers, A. H., Jager, P. L., De Jong, J. R., Van Dongen, G. A. M. S., Schröder, C. P., Lub-De Hooge, M. N. & Kosterink, J. G. W., 20 Apr 2012, In : Pharmaceutisch Weekblad. 147, 16, p. 62-67 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Public-private partnerships in translational medicine: Concepts and practical examples
Luijten, P. R., van Dongen, G. A. M. S., Moonen, C. T., Storm, G. & Crommelin, D. J. A., 2012, In : Journal of Controlled Release. 161, 2, p. 416-421Research output: Contribution to journal › Article › Academic › peer-review
Rapid Visualization of Human Tumor Xenografts through Optical Imaging with a Near-infrared Fluorescent Anti-Epidermal Growth Factor Receptor Nanobody
Oliveira, S., van Dongen, G. A. M. S., Stigter-van Walsum, M., Roovers, R. C., Stam, J. C., Mali, W., van Diest, P. J. & van Bergen en Henegouwen, P. M., 2012, In : Molecular Imaging. 11, 1, p. 33-46Research output: Contribution to journal › Article › Academic › peer-review
Safety and Efficacy of Radioimmunotherapy with 90Yttrium-rituximab in Patients with Relapsed CD20+ B cell Lymphoma: A Feasibility Study
Vaes, M., Bron, D., Vugts, D. J., Paesmans, M., Meuleman, M., Ghanem, G., Guiot, T., Vanderlinden, B., Thielemans, K., van Dongen, G. A. M. S., Flamen, P. & Muylle, K., 2012, In : Journal of Cancer Science & Therapy. 4, 12, p. 394-400Research output: Contribution to journal › Article › Academic
Open Access
File
2011
(89)Zr-Nanocolloidal Albumin-Based PET/CT Lymphoscintigraphy for Sentinel Node Detection in Head and Neck Cancer: Preclinical Results
Heuveling, D. A., Visser, G. W. M., Salumbides - Baclayon, M., Roos, W. H., Wuite, G. J. L., Hoekstra, O. S., Leemans, C. R., de Bree, R. & van Dongen, G. A. M. S., 2011, In : Journal of Nuclear Medicine. 52, 10, p. 1580-1584 5 p.Research output: Contribution to journal › Article › Academic › peer-review
A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth
Roovers, R. C., Vosjan, M. J. W. D., Laeremans, T., el Khoulati, R., de Bruin, R. C. G., Ferguson, K. M., Verkleij, A. J., van Dongen, G. A. M. S. & Henegouwen, P. M. P. V., 2011, In : International Journal of Cancer. 129, 8, p. 2013-2024Research output: Contribution to journal › Article › Academic › peer-review
EATRIS, a Vision for Translational Research in Europe
Becker, R. & van Dongen, G. A. M. S., 2011, In : Journal of Cardiovascular Translational Research. 4, 3, p. 231-237Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
Facile labelling of an anti-epidermal growth factor receptor Nanobody with (68)Ga via a novel bifunctional desferal chelate for immuno-PET
Vosjan, M. J. W. D., Perk, L. R., Roovers, R. C., Visser, G. W. M., Stigter-van Walsum, M., Henegouwen, P. M. P. V. & van Dongen, G. A. M. S., 2011, In : European Journal of Nuclear Medicine and Molecular Imaging. 38, 4, p. 753-763Research output: Contribution to journal › Article › Academic › peer-review
Open Access
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Inert coupling of IRDye800CW to monoclonal antibodies for clinical optical imaging of tumor targets
Cohen, R., Stammes, M. A., de Roos, I. H. C., Stigter-van Walsum, M., Visser, G. W. M. & van Dongen, G. A. M. S., 2011, In : EJNMMI Research. 1, 1, p. 31Research output: Contribution to journal › Article › Academic › peer-review
Open Access
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Preclinical evaluation and validation of [(18)F]HX4, a promising hypoxia marker for PET imaging
Dubois, L. J., Lieuwes, N. G., Janssen, M. H. M., Peeters, W. J. M., Windhorst, A. D., Walsh, J. C., Kolb, H. C., Ollers, M. C., Bussink, J., van Dongen, G. A. M. S., van der Kogel, A. & Lambin, P., 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 35, p. 14620-14625Research output: Contribution to journal › Article › Academic › peer-review
Radioactieve labeling van monoklonale antilichamen en de mogelijkheden van nucleaire beeldvorming
van Dongen, G. A. M. S., 2011, In : Angiogenese Journaal. 1, p. 13-15Research output: Contribution to journal › Article › Professional
Synthesis of Phosphine and Antibody-Azide Probes for in Vivo Staudinger Ligation in a Pretargeted Imaging and Therapy Approach
Vugts, D. J., Vervoort, A., Stigter-van Walsum, M., Visser, G. W. M., Robillard, M. S., Versteegen, R. M., Vulders, R. C. M., Herscheid, J. D. M. & van Dongen, G. A. M. S., 2011, In : Bioconjugate chemistry. 22, 10, p. 2072-2081Research output: Contribution to journal › Article › Academic › peer-review
The potential role of non-FDG-PET in the management of head and neck cancer
Heuveling, D. A., de Bree, R. & van Dongen, G. A. M. S., 2011, In : Oral Oncology. 47, 1, p. 2-7Research output: Contribution to journal › Article › Academic › peer-review
2010
89Zr-bevacizumab PET of early antiangiogenic tumor response to treatment with HSP90 inhibitor NVP-AUY922.
Nagengast, W. B., de Korte, M. A., Oude Munnink, T. H., Timmer-Bosscha, H., den Dunnen, W. F., Hollema, H., de Jong, J. R., Jensen, M. R., Quadt, C., Garcia-Echeverria, C., van Dongen, G. A. M. S., Lub-de Hooge, M. N., Schröder, C. P. & de Vries, E. G. E., 1 May 2010, In : Journal of Nuclear Medicine. 51, 5, p. 761-767 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Biodistribution of Zr-89-trastuzumab and PET Imaging of HER2-Positive Lesions in Patients With Metastatic Breast Cancer
Dijkers, E. C., Munnink, T. H. O., Kosterink, J. G., Brouwers, A. H., de Jager, P. L., de Jong, J. R., van Dongen, G. A. M. S., Schroder, C. P., Lub-de Hooge, M. N. & de Vries, E. G. E., 2010, In : Clinical Pharmacology & Therapeutics. 87, 5, p. 586-592Research output: Contribution to journal › Article › Academic › peer-review
Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine
Vosjan, M. J. W. D., Perk, L. R., Visser, G. W. M., Budde, M., Jurek, P., Kiefer, G. E. & van Dongen, G. A. M. S., 2010, In : Nature Protocols. 5, 4, p. 739-743Research output: Contribution to journal › Article › Academic › peer-review
Immuno-Positron Emission Tomography: Shedding Light on Clinical Antibody Therapy
van Dongen, G. A. M. S. & Vosjan, M. J. W. D., 2010, In : Cancer Biotherapy and Radiopharmaceuticals. 25, 4, p. 375-385Research output: Contribution to journal › Article › Academic › peer-review
Molecular imaging for visualization and quantification of individualized targeted cancer therapy
Lubberink, M., Rizvi, S. N. F., Hoekstra, O. S. & van Dongen, G. A. M. S., 11 Nov 2010, In : MedicaMundi. 54, 2, p. 47-54 8 p.Research output: Contribution to journal › Article › Academic › peer-review
PET imaging of hypoxia using [F-18]HX4: a phase I trial
van Loon, J., Janssen, M. H. M., Ollers, M. C., Aerts, H. J. W. L., Dubois, L., Hochstenbag, M., Dingemans, A. M. C., Lalisang, R., Brans, B., Windhorst, A. D., van Dongen, G. A. M. S., Kolb, H., Zhang, J., De Ruysscher, D. & Lambin, P., 2010, In : European Journal of Nuclear Medicine and Molecular Imaging. 37, 9, p. 1663-1668Research output: Contribution to journal › Article › Academic › peer-review
Open Access
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PET of Hypoxia with Zr-89-Labeled cG250-F(ab ')(2) in Head and Neck Tumors
Hoeben, B. A. W., Kaanders, J. H. A. M., Franssen, G. M., Troost, E. G. C., Rijken, P. F. J. W., Oosterwijk, E., van Dongen, G. A. M. S., Oyen, W. J. G., Boerman, OC. & Bussink, J., 2010, In : Journal of Nuclear Medicine. 51, 7, p. 1076-1083Research output: Contribution to journal › Article › Academic › peer-review
p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging
Perk, L. R., Vosjan, M. J. W. D., Visser, G. W. M., Budde, M., Jurek, P., Kiefer, G. E. & van Dongen, G. A. M. S., 2010, In : European Journal of Nuclear Medicine and Molecular Imaging. 37, 2, p. 250-259Research output: Contribution to journal › Article › Academic › peer-review
File
Sentinel node procedure of the sigmoid using indocyanine green: feasibility study in a goat model
van der Pas, M. H. G. M., van Dongen, G. A. M. S., Cailler, F., Pelegrin, A. & Meijerink, W. J. H. J., 2010, In : Surgical Endoscopy. 24, 9, p. 2182-2187Research output: Contribution to journal › Article › Academic › peer-review
Open Access
File
The ESTRO Breur Lecture 2009. From population to voxel-based radiotherapy: Exploiting intra-tumour and intra-organ heterogeneity for advanced treatment of non-small cell lung cancer
Lambin, P., Petit, S. F., Aerts, H. J. W. L., van Elmpt, W. J. C., Oberije, C. J. G., Starmans, M. H. W., van Stiphout, R. G. P. M., van Dongen, G. A. M. S., Muylle, K., Flamen, P., Dekker, A. L. A. J. & De Ruysscher, D., 2010, In : Radiotherapy and Oncology. 96, 2, p. 145-152Research output: Contribution to journal › Article › Academic › peer-review
Zr-89-trastuzumab PET visualises HER2 downregulation by the HSP90 inhibitor NVP-AUY922 in a human tumour xenograft
Munnink, T. H. O., de Korte, M. A., Nagengast, W. B., Timmer-Bosscha, H., Schroder, C. P., de Jong, J. R., van Dongen, G. A. M. S., Jensen, M. R., Quadt, C., Lub-de Hooge, M. N. & de Vries, E. G. E., 2010, In : European Journal of Cancer. 46, 3, p. 678-684Research output: Contribution to journal › Article › Academic › peer-review
2009
Development and Characterization of Clinical-Grade Zr-89-Trastuzumab for HER2/neu ImmunoPET Imaging
Dijkers, E. C. F., Kosterink, J. G. W., Rademaker, A. C. H. J., Perk, L. R., van Dongen, G. A. M. S., Bart, J., de Jong, J. R., de Vries, E. G. & Lub-de Hooge, M. N., 2009, In : Journal of Nuclear Medicine. 50, 6, p. 974-981Research output: Contribution to journal › Article › Academic › peer-review
Disparity Between In Vivo EGFR Expression and Zr-89-Labeled Cetuximab Uptake Assessed with PET
Aerts, H. J. W. L., Dubois, L., Perk, L. R., Vermaelen, P., van Dongen, G. A. M. S., Wouters, B. G. & Lambin, P., 2009, In : Journal of Nuclear Medicine. 50, 1, p. 123-131Research output: Contribution to journal › Article › Academic › peer-review
I-124-L19-SIP for immuno-PET imaging of tumour vasculature and guidance of I-131-L19-SIP radioimmunotherapy
Tijink, B. M., Perk, L. R., Budde, M., Stigter-van Walsum, M., Visser, G. W. M., Kloet, R. W., Dinkelborg, L. M., Leemans, C. R., Neri, D. & van Dongen, G. A. M. S., 2009, In : European Journal of Nuclear Medicine and Molecular Imaging. 36, 8, p. 1235-1244Research output: Contribution to journal › Article › Academic › peer-review
No harmful impact of 90yttrium-ibritumomab tiuxetan combined with beam on bone marrow microenvironment
Visser, O., Kessler, F., Perk, L., Vosjan, M., Van Dongen, G., Zijlstra, J., Huijgens, P. & Zweegman, S., 2009, In : Blood. 114, 22Research output: Contribution to journal › Article › Academic › peer-review
Radiation Dosimetry of Zr-89-Labeled Chimeric Monoclonal Antibody U36 as Used for Immuno-PET in Head and Neck Cancer Patients
Borjesson, P. K. E., Jauw, Y. W. S., de Bree, R., Roos, J. C., Castelijns, J. A., Leemans, C. R., van Dongen, G. A. M. S. & Boellaard, R., 2009, In : Journal of Nuclear Medicine. 50, 11, p. 1828-1836Research output: Contribution to journal › Article › Academic › peer-review
The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2
Maussang Detaille, D. A. B., Langemeijer, E., Fitzsimons, C. P., Stigter-van Walsum, M., Dijkman, R., Borg, M. K., Slinger, E., Schreiber, A., Michel, D., Tensen, C. P., van Dongen, A. A. M. S., Leurs, R. & Smit, M. J., 2009, In : Cancer Research. 69, 7, p. 2861-9Research output: Contribution to journal › Article › Academic › peer-review
The role of PET in head and neck cancer: more than 18FDG alone
Heuveling, D. A., de Bree, R. & van Dongen, G. A. M. S., 2009, In : Otorinolaringologia. 59, p. 141-145Research output: Contribution to journal › Article › Professional
2008
Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology
Tijink, B. M., Laeremans, T., Budde, M., Stigter-van, W. M., Dreier, T., de Haard, H. J., Leemans, C. R. & van Dongen, G. A. M. S., 2008, In : Molecular Cancer Therapeutics. 7, 8, p. 2288-2297Research output: Contribution to journal › Article › Academic › peer-review