Guus van Dongen

PROF.DR., (Principal Investigator)

1983 …2019
If you made any changes in Pure these will be visible here soon.

Research Output 1983 2019

Filter
Article
2014

Three-Dimensional Histologic Validation of High-Resolution SPECT of Antibody Distributions Within Xenografts

Branderhorst, W., Blezer, E. L. A., Houtkamp, M., Ramakers, R. M., van den Brakel, J. H., Witteveen, H., van der Have, F., van Andel, H. A. G., Vastenhouw, B., Wu, C., Stigter-van Walsum, M., van Dongen, G. A. M. S., Viergever, M. A., Bleeker, W. K. & Beekman, F. J., 2014, In : Journal of Nuclear Medicine. 55, 5, p. 830-837

Research output: Contribution to journalArticleAcademicpeer-review

2013

[C-11]Sorafenib: Radiosynthesis and preclinical evaluation in tumor-bearing mice of a new TKI-PET tracer

Poot, A. J., van der Wildt, B., Stigter-van Walsum, M., Rongen, M., Schuit, R. C., Hendrikse, N. H., Eriksson, P. A. J., van Dongen, G. A. M. S. & Windhorst, A. D., 2013, In : Nuclear Medicine and Biology. 40, 4, p. 488-497

Research output: Contribution to journalArticleAcademicpeer-review

EATRIS, a European initiative to boost translational biomedical research

van Dongen, G. A. M. S., Ussi, A. E., De Man, F. H. & Migliaccio, G., 2013, In : American journal of nuclear medicine and molecular imaging. 3, 2, p. 166-174

Research output: Contribution to journalArticleAcademicpeer-review

Imaging of TKI-Target Interactions for Personalized Cancer Therapy

Poot, A. J., Slobbe, P., Hendrikse, N. H., Windhorst, A. D. & van Dongen, G. A. M. S., 2013, In : Clinical Pharmacology & Therapeutics. 93, 3, p. 239-241

Research output: Contribution to journalArticleAcademicpeer-review

ImmunoPET Imaging of Renal Cell Carcinoma with I-124- and Zr-89-Labeled Anti-CAIX Monoclonal Antibody cG250 in Mice

Stillebroer, A. B., Franssen, G. M., Mulders, P. F. A., Oyen, W. J. G., van Dongen, G. A. M. S., Laverman, P., Oosterwijk, E. & Boerman, OC., 2013, In : Cancer Biotherapy and Radiopharmaceuticals. 28, 7, p. 510-515

Research output: Contribution to journalArticleAcademicpeer-review

Inert coupling of IRDye800CW and zirconium-89 to monoclonal antibodies for single- or dual-mode fluorescence and PET imaging

Cohen, R., Vugts, D. J., Stigter-van Walsum, M., Visser, G. W. M. & van Dongen, G. A. M. S., 2013, In : Nature Protocols. 8, 5, p. 1010-1018

Research output: Contribution to journalArticleAcademicpeer-review

Llama-derived single variable domains (Nanobodies) directed against CXCR7 reduce head and neck cancer cell growth in vivo

Maussang, D., Mujic-Delic, A., Descamps, F. J., Stortelers, C., Stigter-van Walsum, M., Vischer, H. F., van Roy, M., Vosjan, M. J. W. D., Gonzalez-Pajuelo, M., van Dongen, G. A., Merchiers, P., van Rompaey, P. & Smit, M. J., 2013, In : Journal of Biological Chemistry. 288, 41, p. 29562-29572

Research output: Contribution to journalArticleAcademicpeer-review

PET-beeldvorming in geneesmiddelenontwikkeling en toepassing

van Dongen, G. A. M. S., Hoekstra, O. S., Lammertsma, A. A., Vugts, D. J., Hendrikse, N. H. & Windhorst, A. D., 2013, In : Nederlands Tijdschrift voor Oncologie. 10, 175, p. 182

Research output: Contribution to journalArticleProfessional

Phase 0 Microdosing PET Study Using the Human Mini Antibody F16SIP in Head and Neck Cancer Patients

Heuveling, D. A., de Bree, R., Vugts, D. J., Huisman, M. C., Giovannoni, L., Hoekstra, O. S., Leemans, C. R., Neri, D. & van Dongen, G. A. M. S., 2013, In : Journal of Nuclear Medicine. 54, 3, p. 397-401

Research output: Contribution to journalArticleAcademicpeer-review

2012
41 Downloads (Pure)

A novel method to quantify IRDye800CW fluorescent antibody probes ex vivo in tissue distribution studies

Oliveira, S., Cohen, R., Walsum, M. S., van Dongen, G. A. M. S., Elias, S. G., van Diest, P. J., Mali, W. & van Bergen en Henegouwen, P. M., 2012, In : EJNMMI Research. 2, 1, p. 50 50.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Nanobodies Targeting the Hepatocyte Growth Factor: Potential New Drugs for Molecular Cancer Therapy

Vosjan, M. J. W. D., Vercammen, J., Kolkman, J. A., Stigter-van Walsum, M., Revets, H. & van Dongen, G. A. M. S., 2012, In : Molecular Cancer Therapeutics. 11, 4, p. 1017-1025

Research output: Contribution to journalArticleAcademicpeer-review

Nanocolloidal albumin-IRDye 800CW: a near-infrared fluorescent tracer with optimal retention in the sentinel lymph node

Heuveling, D. A., Visser, G. W. M., de Groot, M., de Boer, J. F., Salumbides - Baclayon, M., Roos, W. H., Wuite, G. J. L., Leemans, C. R., de Bree, R. & van Dongen, G. A. M. S., 2012, In : European Journal of Nuclear Medicine and Molecular Imaging. 39, 7, p. 1161-1168 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Nb-90 - a potential PET nuclide: production and labeling of monoclonal antibodies

Radchenko, V., Hauser, H., Eisenhut, M., Vugts, D. J., van Dongen, G. A. M. S. & Roesch, F., 2012, In : Radiochimica acta. 100, 11, p. 857-863

Research output: Contribution to journalArticleAcademicpeer-review

PET imaging with radiolabeled antibodies and tyrosine kinase inhibitors: immuno-PET and TKI-PET

van Dongen, G. A. M. S., Poot, A. J. & Vugts, D. J., 2012, In : Tumor Biology. 33, 3, p. 607-615

Research output: Contribution to journalArticleAcademicpeer-review

PET imaging with small-molecule tyrosine kinase inhibitors: TKI-PET

Slobbe, P., Poot, A. J., Windhorst, A. D. & van Dongen, G. A. M. S., 2012, In : Drug Discovery Today. 17, 21-22, p. 1175-1187

Research output: Contribution to journalArticleAcademicpeer-review

Positronemissietomografie van [ 89Zr]trastuzumab bij patiënten met gemetastaseerde HER2-positieve borstkanker

Dijkers, E. C. F., Munnink, T. H. O., De Vries, E. G. E., Brouwers, A. H., Jager, P. L., De Jong, J. R., Van Dongen, G. A. M. S., Schröder, C. P., Lub-De Hooge, M. N. & Kosterink, J. G. W., 20 Apr 2012, In : Pharmaceutisch Weekblad. 147, 16, p. 62-67 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Public-private partnerships in translational medicine: Concepts and practical examples

Luijten, P. R., van Dongen, G. A. M. S., Moonen, C. T., Storm, G. & Crommelin, D. J. A., 2012, In : Journal of Controlled Release. 161, 2, p. 416-421

Research output: Contribution to journalArticleAcademicpeer-review

Rapid Visualization of Human Tumor Xenografts through Optical Imaging with a Near-infrared Fluorescent Anti-Epidermal Growth Factor Receptor Nanobody

Oliveira, S., van Dongen, G. A. M. S., Stigter-van Walsum, M., Roovers, R. C., Stam, J. C., Mali, W., van Diest, P. J. & van Bergen en Henegouwen, P. M., 2012, In : Molecular Imaging. 11, 1, p. 33-46

Research output: Contribution to journalArticleAcademicpeer-review

45 Downloads (Pure)

Safety and Efficacy of Radioimmunotherapy with 90Yttrium-rituximab in Patients with Relapsed CD20+ B cell Lymphoma: A Feasibility Study

Vaes, M., Bron, D., Vugts, D. J., Paesmans, M., Meuleman, M., Ghanem, G., Guiot, T., Vanderlinden, B., Thielemans, K., van Dongen, G. A. M. S., Flamen, P. & Muylle, K., 2012, In : Journal of Cancer Science & Therapy. 4, 12, p. 394-400

Research output: Contribution to journalArticleAcademic

Open Access
File
2011

(89)Zr-Nanocolloidal Albumin-Based PET/CT Lymphoscintigraphy for Sentinel Node Detection in Head and Neck Cancer: Preclinical Results

Heuveling, D. A., Visser, G. W. M., Salumbides - Baclayon, M., Roos, W. H., Wuite, G. J. L., Hoekstra, O. S., Leemans, C. R., de Bree, R. & van Dongen, G. A. M. S., 2011, In : Journal of Nuclear Medicine. 52, 10, p. 1580-1584 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth

Roovers, R. C., Vosjan, M. J. W. D., Laeremans, T., el Khoulati, R., de Bruin, R. C. G., Ferguson, K. M., Verkleij, A. J., van Dongen, G. A. M. S. & Henegouwen, P. M. P. V., 2011, In : International Journal of Cancer. 129, 8, p. 2013-2024

Research output: Contribution to journalArticleAcademicpeer-review

40 Downloads (Pure)

EATRIS, a Vision for Translational Research in Europe

Becker, R. & van Dongen, G. A. M. S., 2011, In : Journal of Cardiovascular Translational Research. 4, 3, p. 231-237

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
43 Downloads (Pure)

Facile labelling of an anti-epidermal growth factor receptor Nanobody with (68)Ga via a novel bifunctional desferal chelate for immuno-PET

Vosjan, M. J. W. D., Perk, L. R., Roovers, R. C., Visser, G. W. M., Stigter-van Walsum, M., Henegouwen, P. M. P. V. & van Dongen, G. A. M. S., 2011, In : European Journal of Nuclear Medicine and Molecular Imaging. 38, 4, p. 753-763

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
58 Downloads (Pure)

Inert coupling of IRDye800CW to monoclonal antibodies for clinical optical imaging of tumor targets

Cohen, R., Stammes, M. A., de Roos, I. H. C., Stigter-van Walsum, M., Visser, G. W. M. & van Dongen, G. A. M. S., 2011, In : EJNMMI Research. 1, 1, p. 31

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Preclinical evaluation and validation of [(18)F]HX4, a promising hypoxia marker for PET imaging

Dubois, L. J., Lieuwes, N. G., Janssen, M. H. M., Peeters, W. J. M., Windhorst, A. D., Walsh, J. C., Kolb, H. C., Ollers, M. C., Bussink, J., van Dongen, G. A. M. S., van der Kogel, A. & Lambin, P., 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 35, p. 14620-14625

Research output: Contribution to journalArticleAcademicpeer-review

Radioactieve labeling van monoklonale antilichamen en de mogelijkheden van nucleaire beeldvorming

van Dongen, G. A. M. S., 2011, In : Angiogenese Journaal. 1, p. 13-15

Research output: Contribution to journalArticleProfessional

Synthesis of Phosphine and Antibody-Azide Probes for in Vivo Staudinger Ligation in a Pretargeted Imaging and Therapy Approach

Vugts, D. J., Vervoort, A., Stigter-van Walsum, M., Visser, G. W. M., Robillard, M. S., Versteegen, R. M., Vulders, R. C. M., Herscheid, J. D. M. & van Dongen, G. A. M. S., 2011, In : Bioconjugate chemistry. 22, 10, p. 2072-2081

Research output: Contribution to journalArticleAcademicpeer-review

The potential role of non-FDG-PET in the management of head and neck cancer

Heuveling, D. A., de Bree, R. & van Dongen, G. A. M. S., 2011, In : Oral Oncology. 47, 1, p. 2-7

Research output: Contribution to journalArticleAcademicpeer-review

2010

89Zr-bevacizumab PET of early antiangiogenic tumor response to treatment with HSP90 inhibitor NVP-AUY922.

Nagengast, W. B., de Korte, M. A., Oude Munnink, T. H., Timmer-Bosscha, H., den Dunnen, W. F., Hollema, H., de Jong, J. R., Jensen, M. R., Quadt, C., Garcia-Echeverria, C., van Dongen, G. A. M. S., Lub-de Hooge, M. N., Schröder, C. P. & de Vries, E. G. E., 1 May 2010, In : Journal of Nuclear Medicine. 51, 5, p. 761-767 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biodistribution of Zr-89-trastuzumab and PET Imaging of HER2-Positive Lesions in Patients With Metastatic Breast Cancer

Dijkers, E. C., Munnink, T. H. O., Kosterink, J. G., Brouwers, A. H., de Jager, P. L., de Jong, J. R., van Dongen, G. A. M. S., Schroder, C. P., Lub-de Hooge, M. N. & de Vries, E. G. E., 2010, In : Clinical Pharmacology & Therapeutics. 87, 5, p. 586-592

Research output: Contribution to journalArticleAcademicpeer-review

Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine

Vosjan, M. J. W. D., Perk, L. R., Visser, G. W. M., Budde, M., Jurek, P., Kiefer, G. E. & van Dongen, G. A. M. S., 2010, In : Nature Protocols. 5, 4, p. 739-743

Research output: Contribution to journalArticleAcademicpeer-review

Immuno-Positron Emission Tomography: Shedding Light on Clinical Antibody Therapy

van Dongen, G. A. M. S. & Vosjan, M. J. W. D., 2010, In : Cancer Biotherapy and Radiopharmaceuticals. 25, 4, p. 375-385

Research output: Contribution to journalArticleAcademicpeer-review

Molecular imaging for visualization and quantification of individualized targeted cancer therapy

Lubberink, M., Rizvi, S. N. F., Hoekstra, O. S. & van Dongen, G. A. M. S., 11 Nov 2010, In : MedicaMundi. 54, 2, p. 47-54 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

39 Downloads (Pure)

PET imaging of hypoxia using [F-18]HX4: a phase I trial

van Loon, J., Janssen, M. H. M., Ollers, M. C., Aerts, H. J. W. L., Dubois, L., Hochstenbag, M., Dingemans, A. M. C., Lalisang, R., Brans, B., Windhorst, A. D., van Dongen, G. A. M. S., Kolb, H., Zhang, J., De Ruysscher, D. & Lambin, P., 2010, In : European Journal of Nuclear Medicine and Molecular Imaging. 37, 9, p. 1663-1668

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

PET of Hypoxia with Zr-89-Labeled cG250-F(ab ')(2) in Head and Neck Tumors

Hoeben, B. A. W., Kaanders, J. H. A. M., Franssen, G. M., Troost, E. G. C., Rijken, P. F. J. W., Oosterwijk, E., van Dongen, G. A. M. S., Oyen, W. J. G., Boerman, OC. & Bussink, J., 2010, In : Journal of Nuclear Medicine. 51, 7, p. 1076-1083

Research output: Contribution to journalArticleAcademicpeer-review

54 Downloads (Pure)

p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging

Perk, L. R., Vosjan, M. J. W. D., Visser, G. W. M., Budde, M., Jurek, P., Kiefer, G. E. & van Dongen, G. A. M. S., 2010, In : European Journal of Nuclear Medicine and Molecular Imaging. 37, 2, p. 250-259

Research output: Contribution to journalArticleAcademicpeer-review

File
35 Downloads (Pure)

Sentinel node procedure of the sigmoid using indocyanine green: feasibility study in a goat model

van der Pas, M. H. G. M., van Dongen, G. A. M. S., Cailler, F., Pelegrin, A. & Meijerink, W. J. H. J., 2010, In : Surgical Endoscopy. 24, 9, p. 2182-2187

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

The ESTRO Breur Lecture 2009. From population to voxel-based radiotherapy: Exploiting intra-tumour and intra-organ heterogeneity for advanced treatment of non-small cell lung cancer

Lambin, P., Petit, S. F., Aerts, H. J. W. L., van Elmpt, W. J. C., Oberije, C. J. G., Starmans, M. H. W., van Stiphout, R. G. P. M., van Dongen, G. A. M. S., Muylle, K., Flamen, P., Dekker, A. L. A. J. & De Ruysscher, D., 2010, In : Radiotherapy and Oncology. 96, 2, p. 145-152

Research output: Contribution to journalArticleAcademicpeer-review

Zr-89-trastuzumab PET visualises HER2 downregulation by the HSP90 inhibitor NVP-AUY922 in a human tumour xenograft

Munnink, T. H. O., de Korte, M. A., Nagengast, W. B., Timmer-Bosscha, H., Schroder, C. P., de Jong, J. R., van Dongen, G. A. M. S., Jensen, M. R., Quadt, C., Lub-de Hooge, M. N. & de Vries, E. G. E., 2010, In : European Journal of Cancer. 46, 3, p. 678-684

Research output: Contribution to journalArticleAcademicpeer-review

2009

Development and Characterization of Clinical-Grade Zr-89-Trastuzumab for HER2/neu ImmunoPET Imaging

Dijkers, E. C. F., Kosterink, J. G. W., Rademaker, A. C. H. J., Perk, L. R., van Dongen, G. A. M. S., Bart, J., de Jong, J. R., de Vries, E. G. & Lub-de Hooge, M. N., 2009, In : Journal of Nuclear Medicine. 50, 6, p. 974-981

Research output: Contribution to journalArticleAcademicpeer-review

Disparity Between In Vivo EGFR Expression and Zr-89-Labeled Cetuximab Uptake Assessed with PET

Aerts, H. J. W. L., Dubois, L., Perk, L. R., Vermaelen, P., van Dongen, G. A. M. S., Wouters, B. G. & Lambin, P., 2009, In : Journal of Nuclear Medicine. 50, 1, p. 123-131

Research output: Contribution to journalArticleAcademicpeer-review

I-124-L19-SIP for immuno-PET imaging of tumour vasculature and guidance of I-131-L19-SIP radioimmunotherapy

Tijink, B. M., Perk, L. R., Budde, M., Stigter-van Walsum, M., Visser, G. W. M., Kloet, R. W., Dinkelborg, L. M., Leemans, C. R., Neri, D. & van Dongen, G. A. M. S., 2009, In : European Journal of Nuclear Medicine and Molecular Imaging. 36, 8, p. 1235-1244

Research output: Contribution to journalArticleAcademicpeer-review

No harmful impact of 90yttrium-ibritumomab tiuxetan combined with beam on bone marrow microenvironment

Visser, O., Kessler, F., Perk, L., Vosjan, M., Van Dongen, G., Zijlstra, J., Huijgens, P. & Zweegman, S., 2009, In : Blood. 114, 22

Research output: Contribution to journalArticleAcademicpeer-review

The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2

Maussang Detaille, D. A. B., Langemeijer, E., Fitzsimons, C. P., Stigter-van Walsum, M., Dijkman, R., Borg, M. K., Slinger, E., Schreiber, A., Michel, D., Tensen, C. P., van Dongen, A. A. M. S., Leurs, R. & Smit, M. J., 2009, In : Cancer Research. 69, 7, p. 2861-9

Research output: Contribution to journalArticleAcademicpeer-review

The role of PET in head and neck cancer: more than 18FDG alone

Heuveling, D. A., de Bree, R. & van Dongen, G. A. M. S., 2009, In : Otorinolaringologia. 59, p. 141-145

Research output: Contribution to journalArticleProfessional

2008

Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology

Tijink, B. M., Laeremans, T., Budde, M., Stigter-van, W. M., Dreier, T., de Haard, H. J., Leemans, C. R. & van Dongen, G. A. M. S., 2008, In : Molecular Cancer Therapeutics. 7, 8, p. 2288-2297

Research output: Contribution to journalArticleAcademicpeer-review