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Personal profile

Research interests

My research interests are:

1) Deepening understanding of the underlying mechanisms of cognitive decline in MS (elaboration on the work started during my PhD) and;

2) (further) develop my own theme within the MS center Amsterdam: studying the effects of cognitive rehabilitation on behavior and quality of life on the one hand and brain structure and function (i.e. neuronal plasticity) on the other hand.

State-of-the-art neuroimaging measures are key in all projects I am involved in. One of my newest insights is the suggestion of a window-of-opportunity in which the brain seems most receptive for cognitive rehabilitation (i.e. intact functional network functioning). This window-of-opportunity is often missed in current clinical care and cognitive rehabilitation might, hence, often come too late. This finding also suggests that there might be a role for preventative intervention (i.e. making the brain more resilient towards future pathology), an area that I want to explore in the (near) future.

My ultimate goal is to understand the brain to such an extent that I will be able to give patient-tailored advices to prevent, or at least postpone, cognitive decline and to allow patients to live their life as they see fit without being hampered by MS-related cognitive decline. 

Key words: Cognition, state-of-the-art neuroimaging techiques, resilience, quality of life, patient narratives, personalised intervention

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

RTMS affects working memory performance, brain activation and functional connectivity in patients with multiple sclerosis

Hulst, H. E., Goldschmidt, T., Nitsche, M. A., De Wit, S. J., Van Den Heuvel, O. A., Barkhof, F., Paulus, W., Van Der Werf, Y. D. & Geurts, J. J. G., 1 May 2017, In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 5, p. 386-394 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

A pilot study of the effects of running training on visuospatial memory in MS: A stronger functional embedding of the hippocampus in the default-mode network?

Huiskamp, M., Moumdjian, L., van Asch, P., Popescu, V., Schoonheim, M. M., Steenwijk, M. D., Vanzeir, E., van Wijmeersch, B., Geurts, J. J. G., Feys, P. & Hulst, H. E., 1 Jan 2019, (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

De onzichtbare last van cognitieve problemen bij multipele sclerose

Translated title of the contribution: The invisible burden of cognitive problems in patients with multiple sclerosisvan der Hiele, K., Hoogervorst, E. L. J. & Hulst, H. E., 2019, In : Nederlands Tijdschrift voor Geneeskunde. 163, 25

Research output: Contribution to journalArticleProfessional

Information processing speed in multiple sclerosis: Relevance of default mode network dynamics

van Geest, Q., Douw, L., van ‘t Klooster, S., Leurs, C. E., Genova, H. M., Wylie, G. R., Steenwijk, M. D., Killestein, J., Geurts, J. J. G. & Hulst, H. E., 2018, In : NeuroImage: Clinical. 19, p. 507-515

Research output: Contribution to journalArticleAcademicpeer-review

Open Access


Nodig! Cognitieve training voor mensen met progressieve MS

Hanneke Hulst (Organiser)

Activity: Participating in or organising an eventOrganising a conference, workshop, ...

Breinkunde in het onderwijs

Hanneke Hulst (Speaker)

Activity: Talk or presentationInvited talk

Toetsingscommissie Biobank (TcB) (External organisation)

Hanneke Hulst (Member)

Activity: MembershipMembership of committee

International MS Cognition Society: Annual conference 2019

Jeroen Geurts (Chair), Menno Schoonheim (Organiser), Hanneke Hulst (Organiser), Brigit de Jong (Organiser)
6 Jun 20197 Jun 2019

Activity: Participating in or organising an eventOrganising a conference, workshop, ...

Celgene RWE Workshop on cognition

Hanneke Hulst (Consultant)
12 Sep 2019

Activity: Consultancy

Press / Media

Columnist for MSweb

Hanneke Hulst


1 Media contribution

Press/Media: Other

Lezing op Kopfestival Deventer: De zin en onzin van hersenscans

Hanneke Hulst


1 Media contribution

Press/Media: Public Engagement Activities