Hans Niessen

PROF.DR.

1991 …2019
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Research Output 1991 2019

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2019

Depletion of activated macrophages with a folate receptor-beta-specific antibody improves symptoms in mouse models of rheumatoid arthritis

Hu, Y., Wang, B., Shen, J., Low, S. A., Putt, K. S., Niessen, H. W. M., Matteson, E. L., Murphy, L., Ruppert, C., Jansen, G., Oliver, S. J., Feng, Y., Dimitrov, D. S., Nickerson-Nutter, C. & Low, P. S., 2019, In : Arthritis Research and Therapy. 21, 1, 143.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hemangioma of the Atherosclerotic Changed Aortic Valve

van Broekhoven, A., Krijnen, P. A. J., Niessen, H. W. M. & Vonk, A. B. A., 2019, In : Case reports in cardiology. 2019, p. 7916298

Research output: Contribution to journalArticleAcademicpeer-review

Homocysteine-induced inverse expression of tissue factor and DPP4 in endothelial cells is related to NADPH oxidase activity

Korkmaz, H. I., Hahn, N. E., Jansen, K. M., Musters, R. J. P., van Bezu, J., van Wieringen, W. N., van Zuijlen, P. P. M., Ulrich, M. M. W., Niessen, H. W. M. & Krijnen, P. A. J., 2019, In : Physiology International. 106, 1, p. 29-38 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pathogenic effect of a TGFBR1 mutation in a family with Loeys–Dietz syndrome

Cozijnsen, L., Plomp, A. S., Post, J. G., Pals, G., Bogunovic, N., Yeung, K. K., Niessen, H. W. M., Goumans, M-J. T. H., Barge-Schaapveld, D. Q. C. M. & Micha, D., 2019, In : Molecular Genetics and Genomic Medicine. e943.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Pathogenic effect of a TGFBR1 mutation in a family with Loeys-Dietz syndrome.

Cozijnsen, L., Plomp, AS., Post, J. G., Pals, G., Bogunovic, N., Yeung, KK., Niessen, JWM., Goumans, M-J., Barge-Schaapveld, D. Q. C. M. & Micha, D., 2019, In : Molecular Genetics and Genomic Medicine.

Research output: Contribution to journalArticleAcademicpeer-review

Short-term LPS induces aortic valve thickening in ApoE*3Leiden mice

van Broekhoven, A., Krijnen, P. A. J., Fuijkschot, W. W., Morrison, M. C., Zethof, I. P. A., van Wieringen, W. N., Smulders, Y. M., Niessen, H. W. M. & Vonk, A. B. A., 2019, In : European Journal of Clinical Investigation. e13121.

Research output: Contribution to journalArticleAcademicpeer-review

2018

An in vitro method to keep human aortic tissue sections functionally and structurally intact

Meekel, J. P., Groeneveld, M. E., Bogunovic, N., Keekstra, N., Musters, R. J. P., Zandieh-Doulabi, B., Pals, G., Micha, D., Niessen, H. W. M., Wiersema, A. M., Kievit, J. K., Hoksbergen, A. W. J., Wisselink, W., Blankensteijn, J. D. & Yeung, K. K., 1 Dec 2018, In : Scientific Reports. 8, 1, 8094.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Diagnostic yield of a targeted gene panel in primary ciliary dyskinesia patients

Paff, T., Kooi, I. E., Moutaouakil, Y., Riesebos, E., Sistermans, E. A., Daniels, H. J. M. A., Weiss, J. M. M., Niessen, H. H. W. M., Haarman, E. G., Pals, G. & Micha, D., 1 May 2018, In : Human Mutation. 39, 5, p. 653-665 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Elevated monocyte-specific type I interferon signalling correlates positively with cardiac healing in myocardial infarct patients but interferon alpha application deteriorates myocardial healing in rats

Ter Horst, E. N., Krijnen, P. A. J., Hakimzadeh, N., Robbers, L. F. H. J., Hirsch, A., Nijveldt, R., Lommerse, I., Fontijn, R. D., Meinster, E., Delewi, R., van Royen, N., Zijlstra, F., van Rossum, A. C., van der Schoot, C. E., van der Pouw Kraan, T. C. T. M., Horrevoets, A. J., van der Laan, A. M., Niessen, H. W. M. & Piek, J. J., 12 Nov 2018, In : Basic Research in Cardiology. 114, 1, p. 1

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Insulin receptor substrate 2 controls insulin-mediated vasoreactivity and perivascular adipose tissue function in muscle

Turaihi, A. H., Bakker, W., van Hinsbergh, V. W. M., Serné, E. H., Smulders, Y. M., Niessen, H. W. M. & Eringa, E. C., 23 Mar 2018, In : Frontiers in Physiology. 9, MAR, 245.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Lps-induced systemic inflammation does not alter atherosclerotic plaque area or inflammation in ApoE3*Leiden mice in the early phase up to 15 days

Fuijkschot, W. W., Morrison, M. C., Zethof, I. P. A., Krijnen, P. A. J., Kleemann, R., Niessen, H. W. M. & Smulders, Y. M., 2018, In : Shock. 50, 3, p. 360-365

Research output: Contribution to journalArticleAcademicpeer-review

Noncanonical NF-κB signaling in microvessels of atherosclerotic lesions is associated with inflammation, atheromatous plaque morphology and myocardial infarction

Maracle, C. X., Agca, R., Helder, B., Meeuwsen, J. A. L., Niessen, H. W. M., Biessen, E. A. L., de Winther, M. P. J., de Jager, S. C. A., Nurmohamed, M. T. & Tas, S. W., 1 Mar 2018, In : Atherosclerosis. 270, p. 33-41 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

p47phox-Dependent Reactive Oxygen Species Stimulate Nuclear Translocation of the FoxO1 Transcription Factor During Metabolic Inhibition in Cardiomyoblasts

Ter Horst, E. N., Hahn, N. E., Geerts, D., Musters, R. J. P., Paulus, W. J., van Rossum, A. C., Meischl, C., Piek, J. J., Niessen, H. W. M. & Krijnen, P. A. J., 1 Sep 2018, In : Cell Biochemistry and Biophysics. 76, 3, p. 401-410 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Reduction of vascular leakage by imatinib is associated with preserved microcirculatory perfusion and reduced renal injury markers in a rat model of cardiopulmonary bypass

Koning, N. J., de Lange, F., van Meurs, M., Jongman, R. M., Ahmed, Y., Schwarte, L. A., van Nieuw Amerongen, G. P., Vonk, A. B. A., Niessen, H. W., Baufreton, C. & Boer, C., 1 Jun 2018, In : British Journal of Anaesthesia. 120, 6, p. 1165-1175 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Reg proteins direct accumulation of functionally distinct macrophage subsets after myocardial infarction

Lörchner, H., Hou, Y., Adrian-Segarra, J. M., Kulhei, J., Detzer, J., Günther, S., Gajawada, P., Warnecke, H., Niessen, H. W., Pöling, J. & Braun, T., 2018, In : Cardiovascular Research. 114, 12, p. 1667-1679

Research output: Contribution to journalArticleAcademicpeer-review

Sex Differences at the Time of Myectomy in Hypertrophic Cardiomyopathy

Nijenkamp, L. L. A. M., Bollen, I. A. E., van Velzen, H. G., Regan, J. A., van Slegtenhorst, M., Niessen, H. W. M., Schinkel, A. F. L., Krueger, M., Poggesi, C., Ho, C. Y., Kuster, D. W. D., Michels, M. & van der Velden, J., Jun 2018, In : Circulation. Heart failure. 11, 6, e004133.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

StemBell therapy stabilizes atherosclerotic plaques after myocardial infarction

Woudstra, L., Meinster, E., VAN Haren, L., Kay, A. M., Koopman, M., Belien, J. A. M., Morrison, M. C., VAN Rossum, A. C., Helder, M. N., Juffermans, L. J. M., Niessen, H. W. M. & Krijnen, P. A. J., Sep 2018, In : Cytotherapy. 20, 9, p. 1143-1154 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Vitamin D attenuates endothelial dysfunction in uremic rats and maintains human endothelial stability

Cuenca, M. V., Ferrantelli, E., Meinster, E., Pouw, S. M., Kovačević, I., de Menezes, R. X., Niessen, H. W., Beelen, R. H. J., Hordijk, P. L. & Vervloet, M. G., 1 Sep 2018, In : Journal of the American Heart Association. 7, 17, e008776.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

A comparison in therapeutic efficacy of several time points of intravenous StemBell administration in a rat model of acute myocardial infarction

Emmens, R. W., Oedayrajsingh-Varma, M., Woudstra, L., Kamp, O., Meinster, E., van Dijk, A., Helder, M. N., Wouters, D., Zeerleder, S., van Ham, S. M., de Jong, N., Niessen, H. W. M., Juffermans, L. J. M. & Krijnen, P. A. J., Jan 2017, In : Cytotherapy. 19, 1, p. 131-140 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Arterial Blood Pressure Induces Transient C4b-Binding Protein in Human Saphenous Vein Grafts

Kupreishvili, K., Meischl, C., Vonk, A. B. A., Stooker, W., Eijsman, L., Blom, A. M., Quax, P. H. A., van Hinsbergh, V. W. M., Niessen, H. W. M. & Krijnen, P. A. J., May 2017, In : Annals of Vascular Surgery. 41, p. 259-264 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Autopsy after transcatheter aortic valve implantation

van Kesteren, F., Wiegerinck, E. M. A., Rizzo, S., Baan, J., Planken, R. N., von der Thüsen, J. H., Niessen, H. W. M., van Oosterhout, M. F. M., Pucci, A., Thiene, G., Basso, C., Sheppard, M. N., Wassilew, K. & van der Wal, A. C., Mar 2017, In : Virchows Archiv. 470, 3, p. 331-339 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cancer drug addiction is relayed by an ERK2-dependent phenotype switch

Kong, X., Kuilman, T., Shahrabi, A., Boshuizen, J., Kemper, K., Song, J. Y., Niessen, H. W. M., Rozeman, E. A., Foppen, M. H. G., Blank, C. U. & Peeper, D. S., 12 Oct 2017, In : Nature. 550, 7675, p. 270-274 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

CD45 is a more sensitive marker than CD3 to diagnose lymphocytic myocarditis in the endomyocardium

Woudstra, L., Biesbroek, P. S., Emmens, R. W., Heymans, S., Juffermans, L. J., van der Wal, A. C., van Rossum, A. C., Niessen, H. W. M. & Krijnen, P. A. J., Apr 2017, In : Human Pathology. 62, p. 83-90 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

EMC10 (Endoplasmic Reticulum Membrane Protein Complex Subunit 10) Is a Bone Marrow-Derived Angiogenic Growth Factor Promoting Tissue Repair After Myocardial Infarction

Reboll, M. R., Korf-Klingebiel, M., Klede, S., Polten, F., Brinkmann, E., Reimann, I., Schönfeld, H-J., Bobadilla, M., Faix, J., Kensah, G., Gruh, I., Klintschar, M., Gaestel, M. & Niessen, H. W., 7 Nov 2017, In : Circulation. 136, 19, p. 1809-1823 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Investigating histological aspects of scars in children

Westra, I., Verhaegen, P. D. H. M., Ibrahim Korkmaz, H., Braam, K. I., Kaspers, G. J. L., Niessen, H. W. M. & Niessen, F. B., 2 May 2017, In : Journal of Wound Care. 26, 5, p. 256-265 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lymphocytic myocarditis occurs with myocardial infarction and coincides with increased inflammation, hemorrhage and instability in coronary artery atherosclerotic plaques

Woudstra, L., Biesbroek, P. S., Emmens, R. W., Heymans, S., Juffermans, L. J., van Rossum, A. C., Niessen, H. W. M. & Krijnen, P. A. J., 1 Apr 2017, In : International Journal of Cardiology. 232, p. 53-62

Research output: Contribution to journalArticleAcademicpeer-review

Mast cells are increased in the media of coronary lesions in patients with myocardial infarction and may favor atherosclerotic plaque instability

Kupreishvili, K., Fuijkschot, W. W., Vonk, A. B. A., Smulders, Y. M., Stooker, W., Van Hinsbergh, V. W. M., Niessen, H. W. M. & Krijnen, P. A. J., Mar 2017, In : Journal of Cardiology. 69, 3, p. 548-554 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neutrophil extracellular traps coincide with a pro-coagulant status of microcirculatory endothelium in burn wounds

Korkmaz, H. I., Ulrich, M. M. W., Vogels, S., de Wit, T., van Zuijlen, P. P. M., Krijnen, P. A. J. & Niessen, H. W. M., Aug 2017, In : Wound Repair and Regeneration. 25, 4, p. 609-617 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

On the value of therapeutic interventions targeting the complement system in acute myocardial infarction

Emmens, R. W., Wouters, D., Zeerleder, S., van Ham, S. M., Niessen, H. W. M. & Krijnen, P. A. J., Apr 2017, In : Translational research : the journal of laboratory and clinical medicine. 182, p. 103-122 20 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pulmonary endarterectomy for calcified amorphous tumour-related pulmonary hypertension

Bonta, P. I., Bogaard, H. J., van den Berk, I., Niessen, H. W. M., van der Wal, A. & Symersky, P., Jun 2017, In : Thorax. 72, 6, p. 584-585 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

PX-18 Protects Human Saphenous Vein Endothelial Cells under Arterial Blood Pressure

Kupreishvili, K., Stooker, W., Emmens, R. W., Vonk, A. B. A., Sipkens, J. A., van Dijk, A., Eijsman, L., Quax, P. H., van Hinsbergh, V. W. M., Krijnen, P. A. J. & Niessen, H. W. M., Jul 2017, In : Annals of Vascular Surgery. 42, p. 293-298 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Stasis Promotes Erythrocyte Adhesion to von Willebrand Factor

Smeets, M. W. J., Mourik, M. J., Niessen, H. W. M. & Hordijk, P. L., Sep 2017, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 37, 9, p. 1618-1627 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

The Local and Systemic Inflammatory Response in a Pig Burn Wound Model With a Pivotal Role for Complement

Korkmaz, H. I., Ulrich, M. M. W., van Wieringen, W. N., Vlig, M., Emmens, R. W., Meyer, K. W., Sinnige, P., Krijnen, P. A. J., van Zuijlen, P. P. M. & Niessen, H. W. M., 28 Apr 2017, In : Journal of Burn Care and Research. 38, 5, p. e796-e806

Research output: Contribution to journalArticleAcademicpeer-review

2016

Activation of extracellular signal-related kinase in abdominal aortic aneurysm

Groeneveld, M. E., van Burink, M. V., Begieneman, M. P. V., Niessen, H. W. M., Wisselink, W., Eringa, E. & Yeung, K. K., May 2016, In : European Journal of Clinical Investigation. 46, 5, p. 440-447 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cathepsin A-related arteriopathy with strokes and leukoencephalopathy (CARASAL)

Bugiani, M., Kevelam, S. H., Bakels, H. S., Waisfisz, Q., Ceuterick-de Groote, C., Niessen, H. W. M., Abbink, T. E. M., Oberstein, S. A. M. J. L. & van der Knaap, M. S., 25 Oct 2016, In : Neurology. 87, 17, p. 1777-1786 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Colchicine aggravates coxsackievirus B3 infection in mice

Smilde, B. J., Woudstra, L., Hing, G. F., Wouters, D., Zeerleder, S., Murk, J-L., van Ham, M., Heymans, S., Juffermans, L. J. M., van Rossum, A. C., Niessen, H. W. M., Krijnen, P. A. J. & Emmens, R. W., 1 Aug 2016, In : International Journal of Cardiology. 216, p. 58-65 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Correction: Dissecting the Effects of Ischemia and Reperfusion on the Coronary Microcirculation in a Rat Model of Acute Myocardial Infarction

Hollander, M. R., de Waard, G. A., Konijnenberg, L. S. F., Meijer-van Putten, R. M. E., van den Brom, C. E., Paauw, N., de Vries, H. E., van de Ven, P. M., Aman, J., Van Nieuw Amerongen, G. P., Hordijk, P. L., Niessen, H. W. M., Horrevoets, A. J. G. & Van Royen, N., 2016, In : PLoS ONE. 11, 11, p. e0166809

Research output: Contribution to journalArticleAcademicpeer-review

Development of a new therapeutic technique to direct stem cells to the infarcted heart using targeted microbubbles: StemBells

Woudstra, L., Krijnen, P. A. J., Bogaards, S. J. P., Meinster, E., Emmens, R. W., Kokhuis, T. J. A., Bollen, I. A. E., Baltzer, H., Baart, S. M. T., Parbhudayal, R., Helder, M. N., van Hinsbergh, V. W. M., Musters, R. J. P., de Jong, N., Kamp, O., Niessen, H. W. M., van Dijk, A. & Juffermans, L. J. M., Jul 2016, In : Stem Cell Research. 17, 1, p. 6-15

Research output: Contribution to journalArticleAcademicpeer-review

Dissecting the Effects of Ischemia and Reperfusion on the Coronary Microcirculation in a Rat Model of Acute Myocardial Infarction

Hollander, M. R., de Waard, G. A., Konijnenberg, L. S. F., Meijer-van Putten, R. M. E., van den Brom, C. E., Paauw, N., de Vries, H. E., van de Ven, P. M., Aman, J., Van Nieuw-Amerongen, G. P., Hordijk, P. L., Niessen, H. W. M., Horrevoets, A. J. G. & Van Royen, N., 2016, In : PLoS ONE. 11, 7, p. e0157233

Research output: Contribution to journalArticleAcademicpeer-review

Dissecting the Effects of Ischemia and Reperfusion on the Coronary Microcirculation in a Rat Model of Acute Myocardial Infarction

Hollander, M. R., de Waard, G. A., Konijnenberg, L. S. F., Meijer-van Putten, R. M. E., van den Brom, C. E., Paauw, N., de Vries, H. E., van de Ven, P. M., Aman, J., van Nieuw Amerongen, G., Hordijk, P. L., Niessen, H. W. M., Horrevoets, A. J. G. & Van Royen, N., 15 Nov 2016, In : PLoS ONE. 11, 11, e0157233.

Research output: Contribution to journalArticleAcademicpeer-review

Dopamine induces lipid accumulation, NADPH oxidase-related oxidative stress, and a proinflammatory status of the plasma membrane in H9c2 cells

Begieneman, M. P. V., ter Horst, E. N., Rijvers, L., Meinster, E., Leen, R., Pankras, J. E., Fritz, J., Kubat, B., Musters, R. J. P., van Kuilenburg, A. B. P., Stap, J., Niessen, H. W. M. & Krijnen, P. A. J., 1 Nov 2016, In : American Journal of Physiology. Heart and Circulatory Physiology. 311, 5, p. H1097-H1107

Research output: Contribution to journalArticleAcademicpeer-review

Impaired microcirculatory perfusion in a rat model of cardiopulmonary bypass: the role of hemodilution

Koning, N. J., de lange, F., Vonk, A. B. A., Ahmed, Y., van den Brom, C. E., Bogaards, S., van Meurs, M., Jongman, R. M., Schalkwijk, C. G., Begieneman, M. P. V., Niessen, H. W., Baufreton, C. & Boer, C., 1 Mar 2016, In : American Journal of Physiology. Heart and Circulatory Physiology. 310, 5, p. H550-H558

Research output: Contribution to journalArticleAcademicpeer-review

Mitochondrial complex I dysfunction and altered NAD(P)H kinetics in rat myocardium in cardiac right ventricular hypertrophy and failure

Wust, R. C. I., de Vries, H. J., Wintjes, L. T., Rodenburg, R. J., Niessen, H. W. M. & Stienen, G. J. M., 1 Sep 2016, In : Cardiovascular Research. 111, 4, p. 362-372

Research output: Contribution to journalArticleAcademicpeer-review

Myocardial infarction induces atrial inflammation that can be prevented by C1-esterase inhibitor

Begieneman, M. P. V., Emmens, R. W., Rijvers, L., Woudstra, L., Paulus, W. J., Kubat, B., Vonk, A. B. A., van Rossum, A. C., Wouters, D., Zeerleder, S., van Ham, M., Schalkwijk, C. G., Niessen, H. W. M. & Krijnen, P. A. J., Dec 2016, In : Journal of Clinical Pathology. 69, 12, p. 1093-1099 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Myocardial Microvascular Inflammatory Endothelial Activation in Heart Failure With Preserved Ejection Fraction

Franssen, C., Chen, S., Unger, A., Korkmaz, H. I., De Keulenaer, G. W., Tschoepe, C., Leite-Moreira, A. F., Musters, R., Niessen, H. W. M., Linke, W. A., Paulus, W. J. & Hamdani, N., Apr 2016, In : JACC-HEART FAILURE. 4, 4, p. 312-324 13 p.

Research output: Contribution to journalArticleAcademicpeer-review