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Research Output 2002 2019

2019

Contactin-1 and contactin-2 in cerebrospinal fluid as potential biomarkers for axonal domain dysfunction in multiple sclerosis

Chatterjee, M., Koel-Simmelink, M. J., Verberk, I. M., Killestein, J., Vrenken, H., Enzinger, C., Ropele, S., Fazekas, F., Khalil, M. & Teunissen, C. E., 11 Jan 2019, In : Multiple sclerosis journal - experimental, translational and clinical. 4, 4, p. 2055217318819535

Research output: Contribution to journalArticleAcademicpeer-review

Fast Segmentation through surface fairing (FastSURF): A novel semi-automatic hippocampus segmentation method

Bartel, F., Vrenken, H., van Herk, M., de Ruiter, M., Belderbos, J., Hulshof, J. & de Munck, J. C., 2019, In : PLoS ONE. 14, 1, e0210641.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gray matter networks and cognitive impairment in multiple sclerosis

Rimkus, C. M., Schoonheim, M. M., Steenwijk, M. D., Vrenken, H., Eijlers, A. J., Killestein, J., Wattjes, M. P., Leite, C. C., Barkhof, F. & Tijms, B. M., 1 Mar 2019, In : Multiple Sclerosis. 25, 3, p. 382-391

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Inter-observer variation of hippocampus delineation in hippocampal avoidance prophylactic cranial irradiation

Bartel, F., van Herk, M., Vrenken, H., Vandaele, F., Sunaert, S., de Jaeger, K., Dollekamp, N. J., Carbaat, C., Lamers, E., Dieleman, E. M. T., Lievens, Y., de Ruysscher, D., Schagen, S. B., de Ruiter, M. B., de Munck, J. C. & Belderbos, J., Feb 2019, In : Clinical and Translational Oncology. 21, 2, p. 178-186 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lifespan normative data on rates of brain volume changes

MAGNIMS Study Group, 2019, In : Neurobiology of Aging. 81, p. 30-37

Research output: Contribution to journalArticleAcademicpeer-review

Longitudinal spinal cord atrophy in multiple sclerosis using the generalized boundary shift integral

MAGNIMS Study Group, 2019, In : Annals of Neurology.

Research output: Contribution to journalArticleAcademicpeer-review

Non-linear registration improves statistical power to detect hippocampal atrophy in aging and dementia

Bartel, F., Visser, M., de Ruiter, M., Belderbos, J., Barkhof, F., Vrenken, H., de Munck, J. C. & van Herk, M., 2019, In : NeuroImage: Clinical. 23, p. 101902 101902.

Research output: Contribution to journalArticleAcademicpeer-review

Novel imaging phantom for accurate and robust measurement of brain atrophy rates using clinical MRI

Amiri, H., Brouwer, I., Kuijer, J. P. A., de Munck, J. C., Barkhof, F. & Vrenken, H., 1 Jan 2019, In : NeuroImage: Clinical. 21, 101667.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Unraveling treatment response in multiple sclerosis: A clinical and MRI challenge

Gasperini, C., Prosperini, L., Tintoré, M., Sormani, M. P., Filippi, M., Rio, J., Palace, J., Rocca, M. A., Ciccarelli, O., Barkhof, F., Sastre-Garriga, J., Vrenken, H., Frederiksen, J. L., Yousry, T. A., Enzinger, C., Rovira, A., Kappos, L., Pozzilli, C., Montalban, X. & de Stefano, N., 2019, In : Neurology. 92, 4, p. 180-192 13 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

A distributed platform for making large scale manual reference datasets for MS lesion segmentation

Damangir, S., de Sitter, A., Brouwer, I., Guttmann, C. R. G., Pareto, D., Rovira, A., Barkhof, F. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 864-864

Research output: Contribution to journalMeeting AbstractAcademic

Creating accurate reference segmentations of deep GM structures in MS patients by fast semi-automated outlining

de Sitter, A., Bartel, F., Palotai, M., Burggraaff, J., Liu, Y., Simoes, J., Ruggieri, S., Schregel, K., Pinzon, A. M., Ropele, S., Rocca, M. A., Gasperini, C., Gallo, A., Schoonheimm, M., Amann, M., Yiannakas, M., Wattjes, M. P., Sastre-Garriga, J., Kappos, L., Filippi, M. & 7 othersEnzinger, C., Ciccarelli, O., Frederiksen, J., Barkhof, F., Guttmann, C. R. G., de Munck, J. C. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 620-622

Research output: Contribution to journalMeeting AbstractAcademic

Deep gray matter volume loss drives disability worsening in multiple sclerosis

Eshaghi, A., Prados, F., Brownlee, W. J., Altmann, D. R., Tur, C., Cardoso, M. J., De Angelis, F., van de Pavert, S. H., Cawley, N., De Stefano, N., Stromillo, M. L., Battaglini, M., Ruggieri, S., Gasperini, C., Filippi, M., Rocca, M. A., Rovira, A., Sastre-Garriga, J., Vrenken, H., Leurs, C. E. & 11 othersKillestein, J., Pirpamer, L., Enzinger, C., Ourselin, S., Wheeler-Kingshott, C. A. M. G., Chard, D., Thompson, A. J., Alexander, D. C., Barkhof, F., Ciccarelli, O. & on behalf of the MAGNIMS study group, 1 Feb 2018, In : Annals of Neurology. 83, 2, p. 210-222 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

High reproducibility and robustness to lesions, but large software and scanner effects for mean upper cervical cord area (MUCCA) measurement in MS

Weeda, MM., Middelkoop, SM., Steenwijk, MD., Daams, M., Amiri Doumari, H., Brouwer, I., Killestein, J., Uitdehaag, BMJ., Dekker, I., Lukas, C., Bellenberg, B., Barkhof, F., Pouwels, PJW. & Vrenken, H., 6 Nov 2018, (Submitted).

Research output: Contribution to conferenceAbstractAcademic

High reproducibility and robustness to lesions, but large software and scanner effects for mean upper cervical cord area (MUCCA) measurement in MS

Middelkoop, S., Weeda, M. M., Steenwijk, M. D., Daams, M., Amiri, H., Brouwer, I., Killestein, J., Uitdehaag, B. M. J., Dekker, I., Lukas, C., Bellenberg, B., Barkhof, F., Pouwels, P. J. W. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 853-854

Research output: Contribution to journalMeeting AbstractAcademic

MRI-based prediction of conversion from clinically isolated syndrome to clinically definite multiple sclerosis using SVM and lesion geometry

Bendfeldt, K., Taschler, B., Gaetano, L., Madoerin, P., Kuster, P., Mueller-Lenke, N., Amann, M., Vrenken, H., Wottschel, V., Barkhof, F., Borgwardt, S., Klöppel, S., Wicklein, E. M., Kappos, L., Edan, G., Freedman, M. S., Montalbán, X., Hartung, H. P., Pohl, C., Sandbrink, R. & 4 othersSprenger, T., Radue, E. W., Wuerfel, J. & Nichols, T. E., 28 Aug 2018, In : Brain Imaging and Behavior.

Research output: Contribution to journalArticleAcademicpeer-review

Progression of regional grey matter atrophy in multiple sclerosis

Eshaghi, A., Marinescu, R. V., Young, A. L., Firth, N. C., Prados, F., Jorge Cardoso, M., Tur, C., De Angelis, F., Cawley, N., Brownlee, W. J., De Stefano, N., Laura Stromillo, M., Battaglini, M., Ruggieri, S., Gasperini, C., Filippi, M., Rocca, M. A., Rovira, A., Sastre-Garriga, J., Geurts, J. J. G. & 13 othersVrenken, H., Wottschel, V., Leurs, C. E., Uitdehaag, B., Pirpamer, L., Enzinger, C., Ourselin, S., Gandini Wheeler-Kingshott, C. A., Chard, D., Thompson, A. J., Barkhof, F., Alexander, D. C. & Ciccarelli, O., 1 Jun 2018, In : Brain. 141, 6, p. 1665-1677 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Quantification of spinal cord atrophy in MS: which software, which vertebral level, spinal cord or brain MRI? A multi-centric, longitudinal comparison of three different volumetric approaches.

Lukas, C., Prados, F., Valsasina, P., Parmar, K., Brouwer, I., Bellenberg, B., Rovira, A., Chard, D., Kappos, L., Rocca, M. A., Filippi, M., Ciccarelli, O., Barkhof, F. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 88-90

Research output: Contribution to journalMeeting AbstractAcademic

Radiologically isolated syndrome or subclinical multiple sclerosis: MAGNIMS consensus recommendations

De Stefano, N., Giorgio, A., Tintoré, M., Pia Amato, M., Kappos, L., Palace, J., Yousry, T., Rocca, M. A., Ciccarelli, O., Enzinger, C., Frederiksen, J., Filippi, M., Vrenken, H., Rovira, À. & on behalf of the MAGNIMS study group, 1 Feb 2018, In : Multiple Sclerosis. 24, 2, p. 214-221 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Reliability of cross-sectional and longitudinal brain volume measurements in MS patients using FreeSurfer: a multi-vendor MRI study at 3 Tesla

Amiri, H., Renckens, S., Brouwer, I., Bosschaert, S., van Tuijl, R., Hagens, M., Killestein, J., Barkhof, F. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 515-515

Research output: Contribution to journalMeeting AbstractAcademic

Reproducibility of deep gray matter atrophy rate measurement in a large multicenter dataset

Meijerman, A., Amiri, H., Steenwijk, M. D., Jonker, M. A., Van Schijndel, R. A., Cover, K. S. & Vrenken, H., 1 Jan 2018, In : American Journal of Neuroradiology. 39, 1, p. 46-53 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Single Subject Classification of Alzheimer's Disease and Behavioral Variant Frontotemporal Dementia Using Anatomical, Diffusion Tensor, and Resting-State Functional Magnetic Resonance Imaging

Bouts, M. J. R. J., Möller, C., Hafkemeijer, A., van Swieten, J. C., Dopper, E., van der Flier, W. M., Vrenken, H., Wink, A. M., Pijnenburg, Y. A. L., Scheltens, P., Barkhof, F., Schouten, T. M., de Vos, F., Feis, R. A., van der Grond, J., de Rooij, M. & Rombouts, S. A. R. B., 2018, In : Journal of Alzheimer's Disease. 62, 4, p. 1827-1839 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The hippocampus in multiple sclerosis

Rocca, M. A., Barkhof, F., De Luca, J., Frisén, J., Geurts, J. J. G., Hulst, H. E. & MAGNIMS Study Group, 1 Oct 2018, In : The Lancet Neurology. 17, 10, p. 918-926 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Thinner cortex in patients with subjective cognitive decline is associated with steeper decline of memory

Verfaillie, S. C. J., Slot, R. E., Tijms, B. M., Bouwman, F., Benedictus, M. R., Overbeek, J. M., Koene, T., Vrenken, H., Scheltens, P., Barkhof, F. & van der Flier, W. M., 1 Jan 2018, In : Neurobiology of Aging. 61, p. 238-244 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Urgent challenges in quantification and interpretation of brain grey matter atrophy in individual MS patients using MRI

Amiri, H., de Sitter, A., Bendfeldt, K., Battaglini, M., Wheeler-Kingshott, C. A. M. G., Calabrese, M., Geurts, J. J. G., Rocca, M. A., Sastre-Garriga, J., Enzinger, C., de Stefano, N., Filippi, M., Rovira, A., Barkhof, F. & Vrenken, H., 2018, In : NeuroImage: Clinical. 19, p. 466-475

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
2017

A Longitudinal Study on Resting State Functional Connectivity in Behavioral Variant Frontotemporal Dementia and Alzheimer's Disease

Hafkemeijer, A., Möller, C., Dopper, E. G. P., Jiskoot, L. C., Van Den Berg-Huysmans, A. A., Van Swieten, J. C., Van Der Flier, W. M., Vrenken, H., Pijnenburg, Y. A. L., Barkhof, F., Scheltens, P., Van Der Grond, J. & Rombouts, S. A. R. B., 2017, In : Journal of Alzheimer's Disease. 55, 2, p. 521-537 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Impact of removing facial features from MR images of MS patients on automatic lesion and atrophy metrics

de Sitter, A., Visser, M., Brouwer, I., van Schijndel, R. A., Uitdehaag, B. M. J., Barkhof, F. & Vrenken, H., Oct 2017, In : Multiple Sclerosis Journal. 23, p. 226-226

Research output: Contribution to journalMeeting AbstractAcademic

Performance of five research-domain automated WM lesion segmentation methods in a multi-center MS study

de Sitter, A., Steenwijk, M. D., Ruet, A., Versteeg, A., Liu, Y., van Schijndel, R. A., Pouwels, P. J. W., Kilsdonk, I. D., Cover, K. S., van Dijk, B. W., Ropele, S., Rocca, M. A., Yiannakas, M., Wattjes, M. P., Damangir, S., Frisoni, G. B., Sastre-Garriga, J., Rovira, A., Enzinger, C., Filippi, M. & 6 othersFrederiksen, J. L., Ciccarelli, O., Kappos, L., Barkhof, F., Vrenken, H. & for the MAGNIMS study group and for neuGRID, 1 Dec 2017, In : NeuroImage. 163, p. 106-114 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Regional analysis of volumes and reproducibilities of automatic and manual hippocampal segmentations

Bartel, F., Vrenken, H., Bijma, F., Barkhof, F., Van Herk, M. & De Munck, J. C., 1 Feb 2017, In : PLoS ONE. 12, 2, e0166785.

Research output: Contribution to journalArticleAcademicpeer-review

Reproducible segmentation of white matter hyperintensities using a new statistical definition

Damangir, S., Westman, E., Simmons, A., Vrenken, H., Wahlund, L. O. & Spulber, G., 1 Jun 2017, In : Magnetic Resonance Materials in Physics, Biology and Medicine. 30, 3, p. 227-237 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Semi-automatic hippocampus delineation algorithm using surface fairing

Bartel, F., Vrenken, H., van Herk, M., de Ruiter, M. B., Belderbos, J., Hulshof, J. & de Munck, J. C., 2017, EMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017. Springer Verlag, Vol. 65. p. 956-959 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

When East meets West: Comparative studies between neuromyelitis optica and multiple sclerosis through

Liu, Y., 2017

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

WHEN MEASURING HIPPOCAMPAL ATROPHY, DO THE SEGMENTATION NOISE DISTRIBUTIONS OF METHODS, AS DETERMINED BY THE BACK-TO-BACK REPRODUCIBILITY, HAVE GAUSSIAN DISTRIBUTIONS?

Cover, K. S., van Schijndel, R. A., Versteeg, A., Redolfi, A., Bosco, P., Damangir, S., van Dijk, B. W., Vrenken, H., Frisoni, G. B. & Barkhof, F., Jul 2017, p. P1109-P1111.

Research output: Contribution to conferenceAbstractAcademic

2016

Alzheimer Disease and Behavioral Variant Frontotemporal Dementia: Automatic Classification Based on Cortical Atrophy for Single-Subject Diagnosis

Möller, C., Pijnenburg, Y. A. L., van der Flier, W. M., Versteeg, A., Tijms, B., de Munck, J. C., Hafkemeijer, A., Rombouts, S. A. R. B., van der Grond, J., van Swieten, J., Dopper, E., Scheltens, P., Barkhof, F., Vrenken, H. & Wink, A. M., Jun 2016, In : Radiology. 279, 3, p. 838-848

Research output: Contribution to journalArticleAcademicpeer-review

A semi-automatic method for multiple sclerosis lesion segmentation on dual-echo magnetic resonance images: application in a multicenter context

Storelli, L., Pagani, E., Rocca, M. A., Preziosa, P., Gallo, A., Tedeschi, G., Stromillo, M. L., De Stefano, N., Vrenken, H., Thomas, D. L., Mancini, L., Enzinger, C., Fazekas, F. & Filippi, M., Sep 2016, In : Multiple Sclerosis. 22, p. 520-521

Research output: Contribution to journalMeeting AbstractOther research output

A Semiautomatic Method for Multiple Sclerosis Lesion Segmentation on Dual-Echo MR Imaging: Application in a Multicenter Context

Storelli, L., Pagani, E., Rocca, M. A., Horsfield, M. A., Gallo, A., Bisecco, A., Battaglini, M., De Stefano, N., Vrenken, H., Thomas, D. L., Mancini, L., Ropele, S., Enzinger, C., Preziosa, P. & Filippi, M., Nov 2016, In : American Journal of Neuroradiology. 37, 11, p. 2043-2049

Research output: Contribution to journalArticleAcademicpeer-review

Building a manual reference dataset for deep grey matter segmentation: volumetric versus anatomical bias

Burggraaff, J., Prieto, J. C., Simoes, J. P., Liu, Y., Ruggieri, S., Palotai, M., Gasperini, C., Wattjes, M. P., Barkhof, F., Vrenken, H. & Guttmann, C. R. G., Sep 2016, In : Multiple Sclerosis. 22, p. 754-755

Research output: Contribution to journalMeeting AbstractOther research output

Differences in structural covariance brain networks between behavioral variant frontotemporal dementia and Alzheimer's disease

Hafkemeijer, A., Möller, C., Dopper, E. G. P., Jiskoot, L. C., van den Berg-Huysmans, A. A., van Swieten, J. C., van der Flier, W. M., Vrenken, H., Pijnenburg, Y. A. L., Barkhof, F., Scheltens, P., van der Grond, J. & Rombouts, S. A. R. B., Mar 2016, In : Human Brain Mapping. 37, 3, p. 978-988

Research output: Contribution to journalArticleAcademicpeer-review

Different patterns of cortical gray matter loss over time in behavioral variant frontotemporal dementia and Alzheimer's disease

Möller, C., Hafkemeijer, A., Pijnenburg, Y. A. L., Rombouts, S. A. R. B., van der Grond, J., Dopper, E., van Swieten, J., Versteeg, A., Steenwijk, M. D., Barkhof, F., Scheltens, P., Vrenken, H. & van der Flier, W. M., Feb 2016, In : Neurobiology of Aging. 38, p. 21-31

Research output: Contribution to journalArticleAcademicpeer-review

Grey Matter Atrophy in Multiple Sclerosis: Clinical Interpretation Depends on Choice of Analysis Method

Popescu, V., Schoonheim, M. M., Versteeg, A., Chaturvedi, N., Jonker, M., de Menezes, R. X., Garre, F. G., Uitdehaag, B. M. J., Barkhof, F. & Vrenken, H., 8 Jan 2016, In : PLoS ONE. 11, 1, e0143942.

Research output: Contribution to journalArticleAcademicpeer-review