20022020

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Article
2020

Facing privacy in neuroimaging: removing facial features degrades performance of image analysis methods

de Sitter, A., Visser, M., Brouwer, I., Cover, K. S., van Schijndel, R. A., Eijgelaar, R. S., Müller, D. M. J., Ropele, S., Kappos, L., Rovira, Filippi, M., Enzinger, C., Frederiksen, J., Ciccarelli, O., Guttmann, C. R. G., Wattjes, M. P., Witte, M. G., de Witt Hamer, P. C., Barkhof, F., Vrenken, H. & 2 others, MAGNIMS Study Group & Alzheimer’s Disease Neuroimaging Initiative, Feb 2020, In : European Radiology. 30, 2, p. 1062-1074 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2019

Clinically relevant cranio-caudal patterns of cervical cord atrophy evolution in MS

Rocca, M. A., Valsasina, P., Meani, A., Gobbi, C., Zecca, C., Rovira, À., Montalban, X., Kearney, H., Ciccarelli, O., Matthews, L., Palace, J., Gallo, A., Bisecco, A., Gass, A., Eisele, P., Lukas, C., Bellenberg, B., Barkhof, F., Vrenken, H., Preziosa, P. & 3 others, Comi, G., Filippi, M. & MAGNIMS Study Group, 12 Nov 2019, In : Neurology. 93, 20, p. e1852-e1866

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cortical atrophy accelerates as cognitive decline worsens in multiple sclerosis

Eijlers, A. J. C., Dekker, I., Steenwijk, M. D., Meijer, K. A., Hulst, H. E., Pouwels, P. J. W., Uitdehaag, B. M. J., Barkhof, F., Vrenken, H., Schoonheim, M. M. & Geurts, J. J. G., 1 Oct 2019, In : Neurology. 93, 14, p. e1348-e1359

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Fast Segmentation through surface fairing (FastSURF): A novel semi-automatic hippocampus segmentation method

Bartel, F., Vrenken, H., van Herk, M., de Ruiter, M., Belderbos, J., Hulshof, J. & de Munck, J. C., 1 Jan 2019, In : PLoS ONE. 14, 1, e0210641.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gray matter networks and cognitive impairment in multiple sclerosis

Rimkus, C. M., Schoonheim, M. M., Steenwijk, M. D., Vrenken, H., Eijlers, A. J., Killestein, J., Wattjes, M. P., Leite, C. C., Barkhof, F. & Tijms, B. M., 1 Mar 2019, In : Multiple Sclerosis. 25, 3, p. 382-391

Research output: Contribution to journalArticleAcademicpeer-review

Gray matter T1-w/T2-w ratios are higher in Alzheimer's disease

Pelkmans, W., Dicks, E., Barkhof, F., Vrenken, H., Scheltens, P., van der Flier, W. M. & Tijms, B. M., 2019, In : Human Brain Mapping. 40, 13, p. 3900-3909

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Inter-observer variation of hippocampus delineation in hippocampal avoidance prophylactic cranial irradiation

Bartel, F., van Herk, M., Vrenken, H., Vandaele, F., Sunaert, S., de Jaeger, K., Dollekamp, N. J., Carbaat, C., Lamers, E., Dieleman, E. M. T., Lievens, Y., de Ruysscher, D., Schagen, S. B., de Ruiter, M. B., de Munck, J. C. & Belderbos, J., 11 Feb 2019, In : Clinical and Translational Oncology. 21, 2, p. 178-186 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lifespan normative data on rates of brain volume changes

Battaglini, M., Gentile, G., Luchetti, L., Giorgio, A., Vrenken, H., Barkhof, F., Cover, K. S., Bakshi, R., Chu, R., Sormani, M. P., Enzinger, C., Ropele, S., Ciccarelli, O., Wheeler-Kingshott, C., Yiannakas, M., Filippi, M., Rocca, M. A., Preziosa, P., Gallo, A., Bisecco, A. & 8 others, Palace, J., Kong, Y., Horakova, D., Vaneckova, M., Gasperini, C., Ruggeri, S., de Stefano, N. & MAGNIMS Study Group, 1 Sep 2019, In : Neurobiology of Aging. 81, p. 30-37

Research output: Contribution to journalArticleAcademicpeer-review

Longitudinal spinal cord atrophy in multiple sclerosis using the generalized boundary shift integral

Moccia, M., Prados, F., Filippi, M., Rocca, M. A., Valsasina, P., Brownlee, W. J., Zecca, C., Gallo, A., Rovira, A., Gass, A., Palace, J., Lukas, C., Vrenken, H., Ourselin, S., Gandini Wheeler-Kingshott, C. A. M., Ciccarelli, O., Barkhof, F. & MAGNIMS Study Group, 1 Nov 2019, In : Annals of Neurology. 86, 5, p. 704-713

Research output: Contribution to journalArticleAcademicpeer-review

MRI-based prediction of conversion from clinically isolated syndrome to clinically definite multiple sclerosis using SVM and lesion geometry

Bendfeldt, K., Taschler, B., Gaetano, L., Madoerin, P., Kuster, P., Mueller-Lenke, N., Amann, M., Vrenken, H., Wottschel, V., Barkhof, F., Borgwardt, S., Klöppel, S., Wicklein, E. M., Kappos, L., Edan, G., Freedman, M. S., Montalbán, X., Hartung, H. P., Pohl, C., Sandbrink, R. & 4 others, Sprenger, T., Radue, E. W., Wuerfel, J. & Nichols, T. E., 1 Oct 2019, In : Brain Imaging and Behavior. 13, 5, p. 1361-1374

Research output: Contribution to journalArticleAcademicpeer-review

Non-linear registration improves statistical power to detect hippocampal atrophy in aging and dementia

Bartel, F., Visser, M., de Ruiter, M., Belderbos, J., Barkhof, F., Vrenken, H., de Munck, J. C. & van Herk, M., 2019, In : NeuroImage: Clinical. 23, 101902.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Novel imaging phantom for accurate and robust measurement of brain atrophy rates using clinical MRI

Amiri, H., Brouwer, I., Kuijer, J. P. A., de Munck, J. C., Barkhof, F. & Vrenken, H., 1 Jan 2019, In : NeuroImage: Clinical. 21, 101667.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Performance of five automated white matter hyperintensity segmentation methods in a multicenter dataset

Heinen, R., Steenwijk, M. D., Barkhof, F., Biesbroek, J. M., van der Flier, W. M., Kuijf, H. J., Prins, N. D., Vrenken, H., Biessels, G. J., de Bresser, J. & TRACE-VCI study group, 1 Dec 2019, In : Scientific Reports. 9, 1, 16742.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Predicting clinical progression in multiple sclerosis after 6 and 12 years

Dekker, I., Eijlers, A. J. C., Popescu, V., Balk, L. J., Vrenken, H., Wattjes, M. P., Uitdehaag, B. M. J., Killestein, J., Geurts, J. J. G., Barkhof, F. & Schoonheim, M. M., 1 Jun 2019, In : European Journal of Neurology. 26, 6, p. 893-902 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access
2018

Deep gray matter volume loss drives disability worsening in multiple sclerosis

Eshaghi, A., Prados, F., Brownlee, W. J., Altmann, D. R., Tur, C., Cardoso, M. J., De Angelis, F., van de Pavert, S. H., Cawley, N., De Stefano, N., Stromillo, M. L., Battaglini, M., Ruggieri, S., Gasperini, C., Filippi, M., Rocca, M. A., Rovira, A., Sastre-Garriga, J., Vrenken, H., Leurs, C. E. & 11 others, Killestein, J., Pirpamer, L., Enzinger, C., Ourselin, S., Wheeler-Kingshott, C. A. M. G., Chard, D., Thompson, A. J., Alexander, D. C., Barkhof, F., Ciccarelli, O. & MAGNIMS Study Group, 1 Feb 2018, In : Annals of Neurology. 83, 2, p. 210-222 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Progression of regional grey matter atrophy in multiple sclerosis

Eshaghi, A., Marinescu, R. V., Young, A. L., Firth, N. C., Prados, F., Jorge Cardoso, M., Tur, C., De Angelis, F., Cawley, N., Brownlee, W. J., De Stefano, N., Laura Stromillo, M., Battaglini, M., Ruggieri, S., Gasperini, C., Filippi, M., Rocca, M. A., Rovira, A., Sastre-Garriga, J., Geurts, J. J. G. & 13 others, Vrenken, H., Wottschel, V., Leurs, C. E., Uitdehaag, B., Pirpamer, L., Enzinger, C., Ourselin, S., Gandini Wheeler-Kingshott, C. A., Chard, D., Thompson, A. J., Barkhof, F., Alexander, D. C. & Ciccarelli, O., 1 Jun 2018, In : Brain. 141, 6, p. 1665-1677 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Radiologically isolated syndrome or subclinical multiple sclerosis: MAGNIMS consensus recommendations

De Stefano, N., Giorgio, A., Tintoré, M., Pia Amato, M., Kappos, L., Palace, J., Yousry, T., Rocca, M. A., Ciccarelli, O., Enzinger, C., Frederiksen, J., Filippi, M., Vrenken, H., Rovira, À. & MAGNIMS Study Group, 1 Feb 2018, In : Multiple Sclerosis. 24, 2, p. 214-221 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Reproducibility of deep gray matter atrophy rate measurement in a large multicenter dataset

Meijerman, A., Amiri, H., Steenwijk, M. D., Jonker, M. A., Van Schijndel, R. A., Cover, K. S. & Vrenken, H., 1 Jan 2018, In : American Journal of Neuroradiology. 39, 1, p. 46-53 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Single Subject Classification of Alzheimer's Disease and Behavioral Variant Frontotemporal Dementia Using Anatomical, Diffusion Tensor, and Resting-State Functional Magnetic Resonance Imaging

Bouts, M. J. R. J., Möller, C., Hafkemeijer, A., van Swieten, J. C., Dopper, E., van der Flier, W. M., Vrenken, H., Wink, A. M., Pijnenburg, Y. A. L., Scheltens, P., Barkhof, F., Schouten, T. M., de Vos, F., Feis, R. A., van der Grond, J., de Rooij, M. & Rombouts, S. A. R. B., 2018, In : Journal of Alzheimer's Disease. 62, 4, p. 1827-1839 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Thinner cortex in patients with subjective cognitive decline is associated with steeper decline of memory

Verfaillie, S. C. J., Slot, R. E., Tijms, B. M., Bouwman, F., Benedictus, M. R., Overbeek, J. M., Koene, T., Vrenken, H., Scheltens, P., Barkhof, F. & van der Flier, W. M., 1 Jan 2018, In : Neurobiology of Aging. 61, p. 238-244 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

A Longitudinal Study on Resting State Functional Connectivity in Behavioral Variant Frontotemporal Dementia and Alzheimer's Disease

Hafkemeijer, A., Möller, C., Dopper, E. G. P., Jiskoot, L. C., Van Den Berg-Huysmans, A. A., Van Swieten, J. C., Van Der Flier, W. M., Vrenken, H., Pijnenburg, Y. A. L., Barkhof, F., Scheltens, P., Van Der Grond, J. & Rombouts, S. A. R. B., 2017, In : Journal of Alzheimer's Disease. 55, 2, p. 521-537 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

MRI-BASED CLASSIFICATION ACCURACY OF DEMENTIA TYPE IS DETERMINED BY MRI MODALITY

Bouts, M. J. R. J., Möller, C., Hafkemeijer, A., van Swieten, J. C., Dopper, E. G. P., van der Flier, W. M., Vrenken, H., Wink, A. M., Pijnenburg, Y. A. L., Scheltens, P., Barkhof, F., van der Grond, J., de Rooij, M. & Rombouts, S. A. R. B., Jul 2017, In : Alzheimers & Dementia. 13, 7, p. P98-P99

Research output: Contribution to journalArticleAcademicpeer-review

Performance of five research-domain automated WM lesion segmentation methods in a multi-center MS study

de Sitter, A., Steenwijk, M. D., Ruet, A., Versteeg, A., Liu, Y., van Schijndel, R. A., Pouwels, P. J. W., Kilsdonk, I. D., Cover, K. S., van Dijk, B. W., Ropele, S., Rocca, M. A., Yiannakas, M., Wattjes, M. P., Damangir, S., Frisoni, G. B., Sastre-Garriga, J., Rovira, A., Enzinger, C., Filippi, M. & 7 others, Frederiksen, J. L., Ciccarelli, O., Kappos, L., Barkhof, F., Vrenken, H., MAGNIMS Study Group & neuGRID, 1 Dec 2017, In : NeuroImage. 163, p. 106-114 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Regional analysis of volumes and reproducibilities of automatic and manual hippocampal segmentations

Bartel, F., Vrenken, H., Bijma, F., Barkhof, F., Van Herk, M. & De Munck, J. C., 1 Feb 2017, In : PLoS ONE. 12, 2, e0166785.

Research output: Contribution to journalArticleAcademicpeer-review

Reproducible segmentation of white matter hyperintensities using a new statistical definition

Damangir, S., Westman, E., Simmons, A., Vrenken, H., Wahlund, L. O. & Spulber, G., 1 Jun 2017, In : Magnetic Resonance Materials in Physics, Biology and Medicine. 30, 3, p. 227-237 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

Alzheimer Disease and Behavioral Variant Frontotemporal Dementia: Automatic Classification Based on Cortical Atrophy for Single-Subject Diagnosis

Möller, C., Pijnenburg, Y. A. L., van der Flier, W. M., Versteeg, A., Tijms, B., de Munck, J. C., Hafkemeijer, A., Rombouts, S. A. R. B., van der Grond, J., van Swieten, J., Dopper, E., Scheltens, P., Barkhof, F., Vrenken, H. & Wink, A. M., Jun 2016, In : Radiology. 279, 3, p. 838-848

Research output: Contribution to journalArticleAcademicpeer-review

A Semiautomatic Method for Multiple Sclerosis Lesion Segmentation on Dual-Echo MR Imaging: Application in a Multicenter Context

Storelli, L., Pagani, E., Rocca, M. A., Horsfield, M. A., Gallo, A., Bisecco, A., Battaglini, M., De Stefano, N., Vrenken, H., Thomas, D. L., Mancini, L., Ropele, S., Enzinger, C., Preziosa, P. & Filippi, M., Nov 2016, In : American Journal of Neuroradiology. 37, 11, p. 2043-2049

Research output: Contribution to journalArticleAcademicpeer-review

Differences in structural covariance brain networks between behavioral variant frontotemporal dementia and Alzheimer's disease

Hafkemeijer, A., Möller, C., Dopper, E. G. P., Jiskoot, L. C., van den Berg-Huysmans, A. A., van Swieten, J. C., van der Flier, W. M., Vrenken, H., Pijnenburg, Y. A. L., Barkhof, F., Scheltens, P., van der Grond, J. & Rombouts, S. A. R. B., Mar 2016, In : Human Brain Mapping. 37, 3, p. 978-988

Research output: Contribution to journalArticleAcademicpeer-review

Different patterns of cortical gray matter loss over time in behavioral variant frontotemporal dementia and Alzheimer's disease

Möller, C., Hafkemeijer, A., Pijnenburg, Y. A. L., Rombouts, S. A. R. B., van der Grond, J., Dopper, E., van Swieten, J., Versteeg, A., Steenwijk, M. D., Barkhof, F., Scheltens, P., Vrenken, H. & van der Flier, W. M., Feb 2016, In : Neurobiology of Aging. 38, p. 21-31

Research output: Contribution to journalArticleAcademicpeer-review

Grey Matter Atrophy in Multiple Sclerosis: Clinical Interpretation Depends on Choice of Analysis Method

Popescu, V., Schoonheim, M. M., Versteeg, A., Chaturvedi, N., Jonker, M., de Menezes, R. X., Garre, F. G., Uitdehaag, B. M. J., Barkhof, F. & Vrenken, H., 8 Jan 2016, In : PLoS ONE. 11, 1, e0143942.

Research output: Contribution to journalArticleAcademicpeer-review

Impact of APOE-epsilon 4 and family history of dementia on gray matter atrophy in cognitively healthy middle-aged adults

ten Kate, M., Sanz-Arigita, E. J., Tijms, B. M., Wink, A. M., Clerigue, M., Garcia-Sebastian, M., Izagirre, A., Ecay-Torres, M., Estanga, A., Villanua, J., Vrenken, H., Visser, P. J., Martinez-Lage, P. & Barkhof, F., Feb 2016, In : Neurobiology of Aging. 38, p. 14-20

Research output: Contribution to journalArticleAcademicpeer-review

Multicenter Validation of Mean Upper Cervical Cord Area Measurements from Head 3D T1-Weighted MR Imaging in Patients with Multiple Sclerosis

Liu, Y., Lukas, C., Steenwijk, M. D., Daams, M., Versteeg, A., Duan, Y., Li, K., Weiler, F., Hahn, H. K., Wattjes, M. P., Barkhof, F. & Vrenken, H., Apr 2016, In : American Journal of Neuroradiology. 37, 4, p. 749-754

Research output: Contribution to journalArticleAcademicpeer-review

Postmortem Validation of MRI Cortical Volume Measurements in MS

Popescu, V., Klaver, R., Versteeg, A., Voorn, P., Twisk, J. W. R., Barkhof, F., Geurts, J. J. G. & Vrenken, H., Jun 2016, In : Human Brain Mapping. 37, 6, p. 2223-2233

Research output: Contribution to journalArticleAcademicpeer-review

Regional cortical thinning in multiple sclerosis and its relation with cognitive impairment: A multicenter study

Tillema, J. M., Hulst, H. E., Rocca, M. A., Vrenken, H., Steenwijk, M. D., Damjanovic, D., Enzinger, C., Ropele, S., Tedeschi, G., Gallo, A., Ciccarelli, O., Rovira, A., Montalban, X., de Stefano, N., Stromillo, M. L., Filippi, M. & Barkhof, F., Jun 2016, In : Multiple Sclerosis. 22, 7, p. 901-909

Research output: Contribution to journalArticleAcademicpeer-review

Relation between subcortical grey matter atrophy and conversion from mild cognitive impairment to Alzheimer's disease

Yi, H-A., Möller, C., Dieleman, N., Bouwman, F. H., Barkhof, F., Scheltens, P., van der Flier, W. M. & Vrenken, H., Apr 2016, In : Journal of Neurology, Neurosurgery and Psychiatry. 87, 4, p. 425-432

Research output: Contribution to journalArticleAcademicpeer-review

Reproducibility of hippocampal atrophy rates measured with manual, FreeSurfer, AdaBoost, FSL/FIRST and the MAPS-HBSI methods in Alzheimer's disease

Cover, K. S., van Schijndel, R. A., Versteeg, A., Leung, K. K., Mulder, E. R., Jong, R. A., Visser, P. J., Redolfi, A., Revillard, J., Grenier, B., Manset, D., Damangir, S., Bosco, P., Vrenken, H., van Dijk, B. W., Frisoni, G. B. & Barkhof, F., 30 Jun 2016, In : Psychiatry Research: Neuroimaging. 252, p. 26-35 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

White Matter Hyperintensity Volume and Cerebral Perfusion in Older Individuals with Hypertension Using Arterial Spin-Labeling

van Dalen, J. W., Mutsaerts, H. J. M. M., Nederveen, A. J., Vrenken, H., Steenwijk, M. D., Caan, M. W. A., Majoie, C. B. L. M., van Gool, W. A. & Richard, E., Oct 2016, In : American Journal of Neuroradiology. 37, 10, p. 1824-1830

Research output: Contribution to journalArticleAcademicpeer-review

Whole brain functional connectivity in clinically isolated syndrome without conventional brain MRI lesions

Liu, Y., Dai, Z., Duan, Y., Huang, J., Ren, Z., Liu, Z., Dong, H., Shu, N., Vrenken, H., Wattjes, M. P., Barkhof, F., He, Y. & Li, K., Sep 2016, In : European Radiology. 26, 9, p. 2982-2991

Research output: Contribution to journalArticleAcademicpeer-review

2015

Automatic segmentation and volumetry of multiple sclerosis brain lesions from MR images

Jain, S., Sima, D. M., Ribbens, A., Cambron, M., Maertens, A., Van Hecke, W., De Meij, J., Barkhof, F., Steenwijk, M. D., Daams, M., Maes, F., Van Huffel, S., Vrenken, H. & Smeets, D., 2015, In : NeuroImage: Clinical. 8, p. 367-375

Research output: Contribution to journalArticleAcademicpeer-review

Can MS lesion stages be distinguished with MRI? A postmortem MRI and histopathology study

Jonkman, L. E., Lopez Soriano, A., Amor, S., Barkhof, F., van der Valk, P., Vrenken, H. & Geurts, J. J. G., 2015, In : Journal of Neurology. 262, 4, p. 1074-1080

Research output: Contribution to journalArticleAcademicpeer-review