20072019

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2019

Changes in the urinary extracellular vesicle proteome are associated with nephronophthisis-related ciliopathies

Stokman, M. F., Bijnsdorp, I. V., Schelfhorst, T., Pham, T. V., Piersma, S. R., Knol, J. C., Giles, R. H., Bongers, E. M. H. F., Knoers, N. V. A. M., Lilien, M. R., Jiménez, C. R. & Renkema, K. Y., 10 Feb 2019, In : Journal of Proteomics. 192, p. 27-36 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Prostate cancer development is not affected by statin use in patients with elevated psa levels

Meijer, D., van Moorselaar, R. J. A., Vis, A. N. & Bijnsdorp, I. V., 2019, In : Cancers. 11, 7, 953.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Urinary exosomal proteins as (pan-)cancer biomarkers: insights from the proteome

Erozenci, L. A., Böttger, F., Bijnsdorp, I. V. & Jimenez, C. R., 1 Jul 2019, In : FEBS Letters. 593, 13, p. 1580-1597 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

A protocol for urine collection and storage prior to DNA methylation analysis

Bosschieter, J., Bach, S., Bijnsdorp, I. V., Segerink, L. I., Rurup, W. F., van Splunter, A. P., Bahce, I., Novianti, P. W., Kazemier, G., van Moorselaar, R. J. A., Steenbergen, R. D. M. & Nieuwenhuijzen, J. A., 2018, In : PLoS ONE. 13, 8, p. e0200906

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Targeted proteomics in urinary extracellular vesicles identifies biomarkers for diagnosis and prognosis of prostate cancer

Sequeiros, T., Rigau, M., Chiva, C., Montes, M., Garcia-Grau, I., Garcia, M., Diaz, S., Celma, A., Bijnsdorp, I., Campos, A., Di Mauro, P., Borrós, S., Reventós, J., Doll, A., Paciucci, R., Pegtel, M., de Torres, I., Sabidó, E., Morote, J. & Olivan, M., 17 Jan 2017, In : Oncotarget. 8, 3, p. 4960-4976 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

miR-129-3p controls centrosome number in metastatic prostate cancer cells by repressing CP110

Bijnsdorp, I. V., Hodzic, J., Lagerweij, T., Westerman, B., Krijgsman, O., Broeke, J., Verweij, F., Nilsson, R. J. A., Rozendaal, L., van Beusechem, V. W., van Moorselaar, J. A., Wurdinger, T. & Geldof, A. A., 29 Mar 2016, In : Oncotarget. 7, 13, p. 16676-16687

Research output: Contribution to journalArticleAcademicpeer-review

Non-invasive prostate cancer detection by measuring miRNA variants (isomiRs) in urine extracellular vesicles

Koppers-Lalic, D., Hackenberg, M., de Menezes, R., Misovic, B., Wachalska, M., Geldof, A., Zini, N., de Reijke, T., Wurdinger, T., Vis, A., van Moorselaar, J., Pegtel, M. & Bijnsdorp, I., 19 Apr 2016, In : Oncotarget. 7, 16, p. 22566-22578

Research output: Contribution to journalArticleAcademicpeer-review

Protein complexes in urine interfere with extracellular vesicle biomarker studies

Wachalska, M., Koppers-Lalic, D., van Eijndhoven, M. A., Pegtel, DM., Geldof, AA., Lipinska, A. D., van Moorselaar, RJA. & Bijnsdorp, IV., 2016, In : Journal of Circulating Biomarkers. p. 1-6

Research output: Contribution to journalArticleAcademic

2015

[F-18]Fluoromethylcholine as a Chemotherapy Response Read-Out in Prostate Cancer Cells

Oprea, D., van Kanten, M. P., van Moorselaar, R. J. A., van den Eertwegh, A. J. M., van de Ven, P. M., Bijnsdorp, I. V., Hoekstra, O. S. & Geldof, A. A., 2015, In : Molecular Imaging and Biology. 17, 3, p. 319-327

Research output: Contribution to journalArticleAcademicpeer-review

2014

Nontemplated Nucleotide Additions Distinguish the Small RNA Composition in Cells from Exosomes

Lalic, D., Hackenberg, M., Bijnsdorp, I. V., van Eijndhoven, M. A. J., Sadek, P., Sie, D. L. S., Zini, N., Middeldorp, J. M., Ylstra, B., Menezes, R., Wurdinger, T., Meijer, G. A. & Pegtel, D. M., 2014, In : Cell Reports. 8, 6, p. 1649-1658

Research output: Contribution to journalArticleAcademicpeer-review

The novel thymidylate synthase inhibitor trifluorothymidine (TFT) and TRAIL synergistically eradicate non-small cell lung cancer cells

Azijli, K., van Roosmalen, I. A., Smit, J., Pillai, S., Fukushima, M., de Jong, S., Peters, G. J., Bijnsdorp, I. V. & Kruyt, F. A., 2014, In : Cancer Chemotherapy and Pharmacology. 73, 6, p. 1273-1283

Research output: Contribution to journalArticleAcademicpeer-review

2013

ABCC4 Decreases Docetaxel and Not Cabazitaxel Efficacy in Prostate Cancer Cells In Vitro

Oprea, D., Bijnsdorp, I. V., van Moorselaar, R. J. A., van den Eertwegh, A. J. M., Hoekstra, O. S. & Geldof, A. A., 2013, In : Anticancer Research. 33, 2, p. 387-391

Research output: Contribution to journalArticleAcademicpeer-review

Profiling of the calcitonin-calcitonin receptor axis in primary prostate cancer: Clinical implications and molecular correlates

Thakkar, A., Bijnsdorp, I. V., Geldof, A. A. & Shah, G. V., 2013, In : Oncology Reports. 30, 3, p. 1265-1274

Research output: Contribution to journalArticleAcademicpeer-review

Serum testosterone plays an important role in the metastatic ability of castration resistant prostate cancer

van der Sluis, T. M., Bijnsdorp, I. V., Jacobs, J. J. L., Meuleman, E. J. H., Rozendaal, L., Geldof, A. A., van Moorselaar, R. J. A. & Vis, A. N., 2013, In : World Journal of Urology. 31, 2, p. 261-266

Research output: Contribution to journalArticleAcademicpeer-review

2012

TAS-102: more than an antimetabolite

Peters, G. J. & Bijnsdorp, I. V., 2012, In : Lancet Oncology. 13, 12, p. E518-E519

Research output: Contribution to journalArticleAcademicpeer-review

2011

Analysis of drug interactions

Bijnsdorp, I. V., Giovannetti, E. & Peters, G. J., 2011, In : Methods in Molecular Biology. 731, p. 421-434

Research output: Contribution to journalArticleAcademic

Cellular pharmacology of multi- and duplex drugsconsisting of ethynylcytidine and 5-fluoro-2 '-deoxyuridine

Bijnsdorp, I. V., Schwendener, R. A., Schott, H., Fichtner, I., Smid, K., Laan, A. C., Schott, S., Losekoot, N., Honeywell, R. J. & Peters, G. J., 2011, In : Investigational New Drugs. 29, 2, p. 248-257

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
57 Downloads (Pure)

Deoxyribose protects against rapamycin-induced cytotoxicity in colorectal cancer cells in vitro

Bijnsdorp, I. V. & Peters, G. J., 2011, In : Nucleosides, Nucleotides and Nucleic Acids. 30, 12, p. 1197-1202

Research output: Contribution to journalArticleAcademicpeer-review

Lipophilic Prodrugs and Formulations of Conventional (Deoxy) Nucleoside and Fluoropyrimidine Analogs in Cancer

Peters, G. J., Adema, A. D., Bijnsdorp, I. V. & Sandvold, ML., 2011, In : Nucleosides, Nucleotides and Nucleic Acids. 30, 12, p. 1168-1180

Research output: Contribution to journalArticleAcademicpeer-review

Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors

Bijnsdorp, I. V., Capriotti, F., Kruyt, F. A. E., Losekoot, N., Fukushima, M., Griffioen, A. W., Thijssen, V. L. & Peters, G. J., 2011, In : British Journal of Cancer. 104, 7, p. 1185-1192

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
58 Downloads (Pure)
2010

Accumulation of thymidine-derived sugars in thymidine phosphorylase overexpressing cells

Bijnsdorp, I. V., Azijli, K., Jansen, E. E. W., Wamelink, M. M. C., Jakobs, C., Struijs, E. A., Fukushima, M., Kruyt, F. A. E. & Peters, G. J., 2010, In : Biochemical Pharmacology. 80, 6, p. 786-792

Research output: Contribution to journalArticleAcademicpeer-review

Differential activation of cell death and autophagy results in an increased cytotoxic potential for trifluorothymidine compared to 5-fluorouracil in colon cancer cells

Bijnsdorp, I. V., Peters, G. J., Temmink, O. H., Fukushima, M. & Kruyt, F. A. E., 2010, In : International Journal of Cancer. 126, 10, p. 2457-2468

Research output: Contribution to journalArticleAcademicpeer-review

Increased Migration by Stimulation of Thymidine Phosphorylase in Endothelial Cells of Different Origin

Bijnsdorp, I. V., Vrijland, K., Vroling, L., Fukushima, M. & Peters, G. J., 2010, In : Nucleosides, Nucleotides and Nucleic Acids. 29, 4-6, p. 482-487

Research output: Contribution to journalArticleAcademicpeer-review

Molecular mechanism underlying the synergistic interaction between trifluorothymidine and the epidermal growth factor receptor inhibitor erlotinib in human colorectal cancer cell lines

Bijnsdorp, I. V., Kruyt, F. A. E., Fukushima, M., Smid, K., Gokoel, S. & Peters, G. J., 2010, In : Cancer Science. 101, 2, p. 440-447

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
67 Downloads (Pure)

Trifluorothymidine Resistance Is Associated with Decreased Thymidine Kinase and Equilibrative Nucleoside Transporter Expression or Increased Secretory Phospholipase A2

Temmink, O. H., Bijnsdorp, I. V., Prins, H. J., Losekoot, N., Adema, A. D., Smid, K., Honeywell, R. J., Ylstra, B., Eijk, P. P., Fukushima, M. & Peters, G. J., 2010, In : Molecular Cancer Therapeutics. 9, 4, p. 1047-1057

Research output: Contribution to journalArticleAcademicpeer-review

2009

Innovations and Opportunities to Improve Conventional (Deoxy) Nucleoside and Fluoropyrimidine Analogs in Cancer

Adema, A. D., Bijnsdorp, I. V., Sandvold, ML., Verheul, H. M. W. & Peters, G. J., 2009, In : Current Medicinal Chemistry. 16, 35, p. 4632-4643

Research output: Contribution to journalArticleAcademicpeer-review

2008

In vitro activity and mechanism of action of a duplex and multidrug of ethynylcytidine and 5-fluorodeoxyuridine

Bijnsdorp, I. V., Schwendener, R. A., Schott, H., Schott, S., Fichtner, I., Honeywell, R. J., Losekoot, N., Laan, A. C. & Peters, G. J., 2008, In : Nucleic Acids Symposium Series. 52, p. 651

Research output: Contribution to journalArticleAcademic

Synergistic interaction between trifluorothymidine and docetaxel is sequence dependent

Bijnsdorp, I. V., Kruyt, F. A., Gokoel, S., Fukushima, M. & Peters, G. J., 2008, In : Cancer Science. 99, 11, p. 2302-2308

Research output: Contribution to journalArticleAcademicpeer-review

The role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in tumor behavior

Bijnsdorp, I. V., de Bruin, M., Laan, A. C., Fukushima, M. & Peters, G. J., 2008, In : Nucleosides, Nucleotides and Nucleic Acids. 27, 6, p. 681-691

Research output: Contribution to journalArticleAcademicpeer-review

Thymidine phoshorylase as a target for antiangiogenesis treatment

Peters, G. J., Bijnsdorp, I. V. & Fukushima, M., 2008, In : Nucleic Acids Symposium Series. 52, p. 629

Research output: Contribution to journalArticleAcademic

Trifluorothymidine induces cell death independently of p53

Bijnsdorp, I. V., Kruyt, F. A., Fukushima, M. & Peters, G. J., 2008, In : Nucleosides, Nucleotides and Nucleic Acids. 27, 6, p. 699-703

Research output: Contribution to journalArticleAcademicpeer-review

2007

Mechanisms of action of FdUMP[10]: Metabolite activation and thymidylate synthase inhibition

Bijnsdorp, I. V., Comijn, E. M., Padron, J. M., Gmeiner, W. H. & Peters, G. J., 2007, In : Oncology Reports. 18, 1, p. 287-291

Research output: Contribution to journalArticleAcademicpeer-review

Radiosensitizing potential of the selective cyclooygenase-2 (COX-2) inhibitor meloxicam on human glioma cells

Bijnsdorp, I., Kuipers, G., Lafleur, M., Slotman, B., Sminia, P., van de Berg, J., van Rijn, J. & Wedekind, L., 2007, In : Journal of Neuro-Oncology. 85, 1, p. 25-31

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
45 Downloads (Pure)

Radiosensitizing potential of the selective cyclooygenase-2 (COX-2) inhibitor meloxicam on human glioma cells

Bijnsdorp, I. V., van den Berg, J., Kuipers, G. K., Wedekind, L. E., Slotman, B. J., van Rijn, J., Lafleur, M. V. M. & Sminia, P., Oct 2007, In : Journal of Neuro-Oncology. 85, 1, p. 25-31 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Radiosensitizing potential of the selective cyclooygenase-2 (COX-2) inhibitor meloxicam on human glioma cells

Bijnsdorp, I., van den Berg, J., Kuipers, G., Wedekind, L., Slotman, B., van Rijn, J., Lafleur, M. & Sminia, P., 2007, In : Journal of Neuro-Oncology. 85, 1, p. 25-31

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
47 Downloads (Pure)