Irene Bultink

DR., MD PhD

19992019
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Research Output 1999 2019

2019

9 Incidence and determinants of vertebral and peripheral fractures in patients with systemic lupus erythematosus: a prospective longitudinal cohort study

Hadiyen, F. E., Tsang-A-Sjoe, M. WP., Wee, M. M. T., Voskuyl, A. E., Lem, W. F. & Bultink, I. EM., Apr 2019.

Research output: Contribution to conferencePaperAcademic

Bone health, an often forgotten comorbidity in systemic lupus erythematosus: A comment on the new recommendations

Orsolini, G., Bultink, I. E. M., Adami, G., Fassio, A., Viapiana, O., Giollo, A., Gatti, D. & Rossini, M., 2019, In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

Current Treatments and New Developments in the Management of Glucocorticoid-induced Osteoporosis

Raterman, H. G., Bultink, I. E. M. & Lems, W. F., 2019, In : Drugs. 79, 10, p. 1065-1087

Research output: Contribution to journalReview articleAcademicpeer-review

Long-Term Clinical Outcomes in a Cohort of Adults With Childhood-Onset Systemic Lupus Erythematosus

Groot, N., Shaikhani, D., Teng, Y. K. O., de Leeuw, K., Bijl, M., Dolhain, R. J. E. M., Zirkzee, E., Fritsch-Stork, R., Bultink, I. E. M. & Kamphuis, S., 2019, In : Arthritis & rheumatology. 71, 2, p. 290-301 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Glucocorticoids, Inflammation and Bone

Güler-Yüksel, M., Hoes, J. N., Bultink, I. E. M. & Lems, W. F., May 2018, In : Calcified Tissue International. 102, 5, p. 592-606 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

2017

Anti-hinge antibodies recognize IgG subclass- and protease-restricted neoepitopes

Falkenburg, W. J. J., Van Schaardenburg, D., Ooijevaar-De Heer, P., Tsang-A-Sjoe, M. W. P., Bultink, I. E. M., Voskuyl, A. E., Bentlage, A. E. H., Vidarsson, G., Wolbink, G. & Rispens, T., 1 Jan 2017, In : Journal of Immunology. 198, 1, p. 82-93 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bone Disease in Connective Tissue Disease/Systemic Lupus Erythematosus

Bultink, I. E. M., 12 Sep 2017, In : Calcified Tissue International. p. 1-17 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity

Tsang-A-Sjoe, M. W. P., Bultink, I. E. M., Korswagen, L. A., van der Horst, A., Rensink, I., de Boer, M., Hamann, D., Voskuyl, A. E. & Wouters, D., 1 Dec 2017, In : Molecular Immunology. 92, p. 125-131 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Content Validity of a Short Calcium Intake List to Estimate Daily Dietary Calcium Intake of Patients with Osteoporosis

Rasch, L. A., de van der Schueren, M. A. E., van Tuyl, L. H. D., Bultink, I. E. M., de Vries, J. H. M. & Lems, W. F., 1 Mar 2017, In : Calcified Tissue International. 100, 3, p. 271-277 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Inflammatory diseases and bone fragility

Briot, K., Geusens, P., Bultink, I., Lems, W. F. & Roux, C., 1 Dec 2017, In : Osteoporosis International. 28, 12, p. 3301-3314 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study

Kroese, S. J., Abheiden, C. N. H., Blomjous, B. S., Van Laar, J. M., Derksen, R. W. H. M., Bultink, I. E. M., Voskuyl, A. E., Lely, A. T., De Boer, M. A., De Vries, J. I. P. & Fritsch-Stork, R. D. E., 2017, In : Journal of Immunology Research. 2017, 8245879.

Research output: Contribution to journalArticleAcademicpeer-review

PREGNANCY OUTCOME IN WOMEN WITH SYSTEMIC LUPUS ERYTHEMATOSUS, A MULTICENTER COHORT-STUDY

Blomjous, B., Abheiden, C., Kroese, S., van Laar, J., Derksen, R., Bultink, I., Voskuyl, A., Lely, A., de Boer, M., de Vries, J. & Fritsch-Stork, R., Jun 2017, In : Annals of the Rheumatic Diseases. 76, p. 184-184

Research output: Contribution to journalMeeting AbstractAcademic

Prevalence of malnutrition and validation of bioelectrical impedance analysis for the assessment of body composition in patients with systemic sclerosis

Spanjer, M. J., Bultink, I. E. M., de van der Schueren, M. A. E. & Voskuy, A. E., 1 Jun 2017, In : Rheumatology (United Kingdom). 56, 6, p. 1008-1012 5 p., kex014.

Research output: Contribution to journalArticleAcademicpeer-review

Similar efficacy and safety of initial COBRA-light and COBRA therapy in rheumatoid arthritis: 4-year results from the COBRA-light trial

Konijn, N. P. C., van Tuyl, L. H. D., Boers, M., den Uyl, D., ter Wee, M. M., van der Wijden, L. K. M., Bultink, I. E. M., Kerstens, P. J. S. M., Voskuyl, A. E., van Schaardenburg, D., Nurmohamed, M. T. & Lems, W. F., 1 Sep 2017, In : Rheumatology (United Kingdom). 56, 9, p. 1586-1596 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

Autoantibody Specificities and Type I Interferon Pathway Activation in Idiopathic Inflammatory Myopathies

Ekholm, L., Vosslamber, S., Tjarnlund, A., de Jong, T. D., Betteridge, Z., McHugh, N., Plestilova, L., Padyukov, L., Voskuyl, A. E., Bultink, I. E. M., Pegtel, D. M., Mavragani, C. P., Crow, M. K., Vencovsky, J., Lundberg, I. E. & Verweij, C. L., Aug 2016, In : Scandinavian Journal of Immunology. 84, 2, p. 100-109

Research output: Contribution to journalArticleAcademicpeer-review

Effect of twelve-month physical exercise program on patients with osteoporotic vertebral fractures: a randomized, controlled trial

Evstigneeva, L., Lesnyak, O., Bultink, I. E. M., Lems, W. F., Kozhemyakina, E., Negodaeva, E., Guselnikova, G. & Belkin, A., 16 Mar 2016, In : Osteoporosis International. 27, 8, p. 2515-2524 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Fc-gamma receptor polymorphisms differentially influence susceptibility to systemic lupus erythematosus and lupus nephritis

Tsang-A-Sjoe, M. W. P., Nagelkerke, S. Q., Bultink, I. E. M., Geissler, J., Tanck, M. W. T., Tacke, C. E., Ellis, J. A., Zenz, W., Bijl, M., Berden, J. H., de Leeuw, K., Derksen, R. H., Kuijpers, T. W. & Voskuyl, A. E., May 2016, In : Rheumatology. 55, 5, p. 939-948

Research output: Contribution to journalArticleAcademicpeer-review

FSAP-mediated nucleosome release from late apoptotic cells is inhibited by autoantibodies present in SLE

Marsman, G., Stephan, F., de Leeuw, K., Bulder, I., Ruinard, J. T., Westra, J., Bultink, I. E. M., Voskuyl, A. E., Aarden, L. A., Luken, B. M., Kallenberg, C. G. M. & Zeerleder, S., Mar 2016, In : European Journal of Immunology. 46, 3, p. 762-771

Research output: Contribution to journalArticleAcademicpeer-review

HIGH PREVALENCE OF REDUCED BONE MINERAL DENSITY AND UNDERTREATMENT OF OSTEOPOROSIS IN PATIENTS WITH SYSTEMIC SCLEROSIS

Spanjer, M. J., Voskuyl, A. E., Lems, W. F. & Bultink, I. E. M., Jun 2016, In : Annals of the Rheumatic Diseases. 75, p. 1109-1110

Research output: Contribution to journalArticleAcademicpeer-review

Lupus and fractures.

Bultink, I. E. M. & Lems, W. F., Jul 2016, In : Current Opinion in Rheumatology. 28, 4, p. 426-32 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Off-label use of rituximab for systemic lupus erythematosus in Europe

Rydén-Aulin, M., Boumpas, D., Bultink, I., Callejas Rubio, J. L., Caminal-Montero, L., Castro, A., Colodro Ruiz, A., Doria, A., Dörner, T., Gonzalez-Echavarri, C., Gremese, E., Houssiau, F. A., Huizinga, T., Inanç, M., Isenberg, D., Iuliano, A., Jacobsen, S., Jimenéz-Alonso, J., Kovács, L., Mariette, X. & 13 othersMosca, M., Nived, O., Oristrell, J., Ramos-Casals, M., Rascón, J., Ruiz-Irastorza, G., Sáez-Comet, L., Salvador Cervelló, G., Sebastiani, G. D., Squatrito, D., Szücs, G., Voskuyl, A. & van Vollenhoven, RF., 2016, In : Lupus Science and Medicine. 3, 1, p. e000163

Research output: Contribution to journalArticleAcademicpeer-review

Physiological evidence for diversification of IFN alpha- and IFN beta-mediated response programs in different autoimmune diseases

de Jong, T. D., Vosslamber, S., Mantel, E., de Ridder, S., Wesseling, J. G., van der Pouw Kraan, T., Leurs, C., Hegen, H., Deisenhammer, F., Killestein, J., Lundberg, I. E., Vencovsky, J., Nurmohamed, M. T., van Schaardenburg, D., Bultink, I. E. M., Voskuyl, AE., Pegtel, DM., van der Laken, C. J., Bijlsma, J. W. J. & Verweij, C. L., 17 Feb 2016, In : Arthritis Research & Therapy. 18, 49.

Research output: Contribution to journalArticleAcademicpeer-review

PHYSIOLOGICAL EVIDENCE FOR DIVERSIFICATION OF IFN alpha- AND IFN beta-MEDIATED RESPONSE PROGRAMS IN DIFFERENT AUTOIMMUNE DISEASES

de Jong, T. D., Vosslamber, S., Mantel, E., de Ridder, S., Wesseling, J. G., Kraan, T. C. T. M. V. D. P., Leurs, C., Hegen, H., Deisenhammer, F., Killestein, J., Lundberg, I. E., Vencovsky, J., Nurmohamed, M. T., van Schaardenburg, D., Bultink, I. E. M., Voskuyl, A. E., Pegtel, D. M., van der Laken, C. J., Bijlsma, J. W. & Verweij, C. L., Feb 2016, In : Annals of the Rheumatic Diseases. 75, p. A52-A52

Research output: Contribution to journalMeeting AbstractAcademic

Sensing of latent EBV infection through exosomal transfer of 5'pppRNA

Baglio, S. R., van Eijndhoven, M. A. J., Koppers-Lalic, D., Berenguer, J., Lougheed, S. M., Gibbs, S., Leveille, N., Rinkel, R. N. P. M., Hopmans, E. S., Swaminathan, S., Verkuijlen, S. A. W. M., Scheffer, G. L., van Kuppeveld, F. J. M., de Gruijl, T. D., Bultink, I. E. M., Jordanova, E. S., Hackenberg, M., Piersma, S. R., Knol, J. C., Voskuyl, A. E. & 4 othersWurdinger, T., Jimenez, C. R., Middeldorp, J. M. & Pegtel, D. M., 2 Feb 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 5, p. E587-E596

Research output: Contribution to journalArticleAcademicpeer-review

2015

A short, quick, and easy questionnaire to estimate daily dietary calcium intake of osteoporosis patients

L.A., R., M.A.E., D. V. D. S., L.H.D., V. T., I.E.M., B. & W.F., L., 2015, In : Annals of the Rheumatic Diseases. 74, p. 1201 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Estimation of dietary calcium intake

Rasch, L. A., van Tuyl, L. H. D., van Bokhorst-de van der Schueren, M. A. E., Bultink, I. E. M. & Lems, W. F., 2015, In : Osteoporosis International. 26, 2, p. 835-836

Research output: Contribution to journalArticleAcademicpeer-review

Glucocorticoid safety for treating rheumatoid arthritis

Rasch, L. A., Bultink, I. E. M., van Tuyl, L. H. D. & Lems, W. F., 2015, In : Expert opinion on drug safety. 14, 6, p. 839-844

Research output: Contribution to journalArticleAcademicpeer-review

Help! Mijn bisforfonaat doet het niet meer?!

Hoes, J. N., Bultink, I. E. M., de Jongh, R. T. & Lems, W. F., 2015, In : Osteoporose Journaal. april, p. 19-21

Research output: Contribution to journalArticleProfessional

Management of osteoporosis in rheumatoid arthritis patients

Hoes, J. N., Bultink, I. E. & Lems, W. F., 2015, In : Expert Opinion on Pharmacotherapy. 16, 4, p. 559-571

Research output: Contribution to journalArticleAcademicpeer-review

Patiënte met osteopenie en reumatoïde artritis: wel of niet behandelen?

Hoes, J. N., Bultink, I. E. M., de Jongh, R. T. & Lems, W. F., 2015, In : Osteoporose. januari, p. 11-13

Research output: Contribution to journalArticleProfessional

Systemic lupus erythematosus: review of synthetic drugs

Tsang-A-Sjoe, M. W. P. & Bultink, I. E. M., 2015, In : Expert Opinion on Pharmacotherapy. 16, 18, p. 2793-2806

Research output: Contribution to journalArticleAcademicpeer-review

Systemic lupus erythematosus and fractures

Bultink, I. E. M. & Lems, W. F., 2015, In : RMD Open. 1, Suppl 1, e000069.

Research output: Contribution to journalArticleAcademicpeer-review

The association between FOK-I vitamin D receptor gene polymorphisms and bone mineral density in patients with systemic lupus erythematosus

Jacobs, J., Voskuyl, A. E., Korswagen, LA., Theunissen, R., Tervaert, J. W. C. & Bultink, I. E. M., 2015, In : Clinical and Experimental Rheumatology. 33, 5, p. 765-765

Research output: Contribution to journalArticleAcademicpeer-review

2014

Elevated risk of clinical fractures and associated risk factors in patients with systemic lupus erythematosus versus matched controls: a population-based study in the United Kingdom

Bultink, I. E. M., Harvey, N. C., Lalmohamed, A., Cooper, C., Lems, W. F., van Staa, TP. & de Vries, F., 2014, In : Osteoporosis International. 25, 4, p. 1275-1283

Research output: Contribution to journalArticleAcademicpeer-review

Long-term evaluation of antimalarials in a Dutch SLE cohort: intolerance and other reasons for non-use

Tsang, A. S., Bultink, I. E. M. & Voskuyl, A. E., 2014, In : Clinical and Experimental Rheumatology. 32, 1, p. 95-100

Research output: Contribution to journalArticleAcademicpeer-review

Making the invisible visible: bioelectrical impedance analysis demonstrates unfavourable body composition in rheumatoid arthritis patients in clinical practice

Konijn, N. P. C., van Tuyl, L. H. D., Bultink, I. E. M., Lems, W. F., Earthman, C. P. & van Bokhorst-de van der Schueren, M. A. E., 2014, In : Scandinavian Journal of Rheumatology. 43, 4, p. 273-278

Research output: Contribution to journalArticleAcademicpeer-review

Optimizing fracture prevention: the fracture liaison service, an observational study

Eekman, D. A., van Helden, S. H., Huisman, A. M., Verhaar, H. J. J., Bultink, I. E. M., Geusens, P. P., Lips, P. T. A. M. & Lems, W. F., 2014, In : Osteoporosis International. 25, 2, p. 701-709

Research output: Contribution to journalArticleAcademicpeer-review