Research Output per year
Research Output 1998 2019
- 1 - 50 out of 146 results
- Publication Year, Title (descending)
Cerebrospinal Fluid Amyloid-β Subtypes in Confirmed Frontotemporal Lobar Degeneration Cases: A Pilot Study
Verwey, N. A., Teunissen, C. E., Hoozemans, J. J. M., Rozemuller, A. J. M., Scheltens, P. & Pijnenburg, Y. A. L., 2019, In : Journal of Alzheimer's Disease. 71, 1, p. 15-20Research output: Contribution to journal › Article › Academic › peer-review
Characterization of brainstem TDP-43 distribution in FTD cases with ALS features
Scarioni, M., Gami-Patel, P., Timar, Y. S., Rozemuller, A. J., Hoozemans, J. J., Aronica, E., Raaphorst, J., Pijnenburg, Y. A. & Dijkstra, A. A., Jul 2019, In : European Journal of Neurology. 26, p. 436-436Research output: Contribution to journal › Meeting Abstract › Academic
EIF2AK3 variants in Dutch patients with Alzheimer's disease
Wong, T. H., van der Lee, S. J., van Rooij, J. G. J., Meeter, L. H. H., Frick, P., Melhem, S., Seelaar, H., Ikram, M. A., Rozemuller, A. J., Holstege, H., Hulsman, M., Uitterlinden, A., Neumann, M., Hoozemans, J. J. M., van Duijn, C. M., Rademakers, R. & van Swieten, J. C., 1 Jan 2019, In : Neurobiology of Aging. 73, p. 229.e11-229.e18Research output: Contribution to journal › Article › Academic › peer-review
Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology
Wiersma, V. I., van Ziel, A. M., Vazquez-Sanchez, S., Nölle, A., Berenjeno-Correa, E., Bonaterra-Pastra, A., Clavaguera, F., Tolnay, M., Musters, R. J. P., van Weering, J. R. T., Verhage, M., Hoozemans, J. J. M. & Scheper, W., 2019, In : Acta Neuropathologica.Research output: Contribution to journal › Article › Academic › peer-review
Identification of amyloid-beta (Aβ) plaques in freshly frozen human brain tissue using Raman spectroscopy
Lochocki, B., Morrema, T. H. J., Ariese, F., Hoozemans, J. J. M. & De Boer, J. F., 1 Jan 2019, Clinical and Preclinical Optical Diagnostics II. Brown, J. Q. & van Leeuwen, T. G. (eds.). SPIE, Vol. 11073. 1107302. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11073).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Imaging of Aβ-deposits in ex-vivo Alzheimer's disease brain tissue using Raman spectroscopy (Conference Presentation)
Lochocki, B., Morrema, T. H. J., den Haan, J., Ariese, F., Bouwman, F. H., Hoozemans, J. J. & de Boer, J. F., 4 Mar 2019.Research output: Contribution to conference › Paper › Academic
Laser microdissection for spatial proteomics of postmortem brain tissue
Hondius, D. C., Hoozemans, J. J. M., Rozemuller, A. J. M. & Smit, A. B., 1 Jan 2019, Neuromethods. Humana Press Inc., p. 43-53 11 p. (Neuromethods; vol. 146).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
Naturally occurring antibodies isolated from PD patients inhibit synuclein seeding in vitro and recognize Lewy pathology
Li, X., Koudstaal, W., Fletcher, L., Costa, M., van Winsen, M., Siregar, B., Inganäs, H., Kim, J., Keogh, E., Macedo, J., Holland, T., Perry, S., Bard, F., Hoozemans, J. J., Goudsmit, J., Apetri, A. & Pascual, G., 2019, In : Acta Neuropathologica.Research output: Contribution to journal › Article › Academic › peer-review
Von Economo neurons are part of a larger neuronal population that are selectively vulnerable in C9orf72 frontotemporal dementia
Gami-Patel, P., van Dijken, I., van Swieten, J. C., Pijnenburg, Y. A. L., Rozemuller, A. J. M., Hoozemans, J. J. M., Dijkstra, A. A. & Netherlands Brain Bank, 1 Dec 2019, In : Neuropathology and Applied Neurobiology. 45, 7, p. 671-680Research output: Contribution to journal › Review article › Academic › peer-review
A common antigenic motif recognized by naturally occurring human V H 5-51/V L 4-1 anti-tau antibodies with distinct functionalities
Apetri, A., Crespo, R., Juraszek, J., Pascual, G., Janson, R., Zhu, X., Zhang, H., Keogh, E., Holland, T., Wadia, J., Verveen, H., Siregar, B., Mrosek, M., Taggenbrock, R., Ameijde, J., Inganäs, H., van Winsen, M., Koldijk, M. H., Zuijdgeest, D., Borgers, M. & 13 others , 2018, In : Acta Neuropathologica Communinications. 6, 1, p. 43 43.Research output: Contribution to journal › Article › Academic › peer-review
A Laser Microdissection-Liquid Chromatography-Tandem Mass Spectrometry Workflow for Post-mortem Analysis of Brain Tissue
Hondius, D. C., Hoozemans, J. J. M., Rozemuller, A. J. M., Li, K. W. & Smit, A. B., 2018, In : Methods in Molecular Biology. 1723, p. 371-383 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Amyloid-beta and phosphorylated tau in post-mortem Alzheimer's disease retinas
den Haan, J., Morrema, T. H. J., Verbraak, F. D., de Boer, J. F., Scheltens, P., Rozemuller, A. J., Bergen, A. A. B., Bouwman, F. H. & Hoozemans, J. J., 2018, In : Acta Neuropathologica Communinications. 6, 1, p. 147Research output: Contribution to journal › Article › Academic › peer-review
Common antigenic motif recognized by human VH5-51/VL4-1 tau antibodies with distinct functionalities
Apetri, A. C., Crespo, R., Juraszek, J., Pascual, G., Janson, R., Zhu, X., Keogh, E., Zhang, H., Holland, T., Wadia, J., Verveen, H., Siregar, B., Mrosek, M., Taggenbrock, R., van Ameijde, J., Inganas, H., van Winsen, M., Koldijk, M., Zuijdgeest, D., Borgers, M. & 13 others , 2018, In : Biorxiv.Research output: Contribution to journal › Article › Academic › peer-review
Contactin-2, a synaptic and axonal protein, is reduced in cerebrospinal fluid and brain tissue in Alzheimer's disease
Chatterjee, M., Del Campo, M., Morrema, T. H. J., de Waal, M., van der Flier, W. M., Hoozemans, J. J. M. & Teunissen, C. E., 1 Jun 2018, In : Alzheimer's Research & Therapy. 10, 1, p. 52Research output: Contribution to journal › Article › Academic › peer-review
Diagnosing frontotemporal dementia: clinico-pathological correlations in the Dutch population
Scarioni, M., Gami-Patel, P., van Swieten, J. C., Rozemuller, A., Dols, A., Hoozemans, J. J., Pijnenburg, Y. A. & Dijkstra, A. A., Jun 2018, In : European Journal of Neurology. 25, p. 478-478Research output: Contribution to journal › Meeting Abstract › Academic
Different curcumin forms selectively bind fibrillar amyloid beta in post mortem Alzheimer's disease brains: Implications for in-vivo diagnostics
den Haan, J., Morrema, T. H. J., Rozemuller, A. J., Bouwman, F. H. & Hoozemans, J. J. M., 9 Aug 2018, In : Acta Neuropathologica Communinications. 6, 1, p. 75Research output: Contribution to journal › Article › Academic › peer-review
Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser 422 containing epitope on pathological tau
van Ameijde, J., Crespo, R., Janson, R., Juraszek, J., Siregar, B., Verveen, H., Sprengers, I., Nahar, T., Hoozemans, J. J., Steinbacher, S., Willems, R., Delbroek, L., Borgers, M., Dockx, K., van Kolen, K., Mercken, M., Pascual, G., Koudstaal, W. & Apetri, A., 2018, In : Acta Neuropathologica Communinications. 6, 1, 59.Research output: Contribution to journal › Article › Academic › peer-review
Identification of the allosteric P2X receptor antagonist [C]SMW139 as a PET tracer of microglial activation
Janssen, B., Vugts, D. J., Wilkinson, S. M., Ory, D., Chalon, S., Hoozemans, J. J. M., Schuit, R. C., Beaino, W., Kooijman, E. J. M., van den Hoek, J., Chishty, M., Doméné, A., Van der Perren, A., Villa, A., Maggi, A., Molenaar, G. T., Funke, U., Shevchenko, R. V., Baekelandt, V., Bormans, G. & 3 others , 26 Apr 2018, In : Scientific Reports. 8, 1, p. 6580Research output: Contribution to journal › Article › Academic › peer-review
Neuroinflammation is increased in the parietal cortex of atypical Alzheimer's disease
Boon, B. D. C., Hoozemans, J. J. M., Lopuhaä, B., Eigenhuis, K. N., Scheltens, P., Kamphorst, W., Rozemuller, A. J. M. & Bouwman, F. H., 29 May 2018, In : Journal of Neuroinflammation. 15, 1, p. 170Research output: Contribution to journal › Article › Academic › peer-review
Neuropathology and cognitive performance in self-reported cognitively healthy centenarians
Ganz, A. B., Beker, N., Hulsman, M., Sikkes, S., Netherlands Brain Bank, Scheltens, P., Smit, A. B., Rozemuller, A. J. M., Hoozemans, J. J. M. & Holstege, H., 2018, In : Acta Neuropathologica Communinications. 6, 1, p. 64Research output: Contribution to journal › Article › Academic › peer-review
Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer's disease
Hondius, D. C., Eigenhuis, K. N., Morrema, T. H. J., van der Schors, R. C., van Nierop, P., Bugiani, M., Li, K. W., Hoozemans, J. J. M., Smit, A. B. & Rozemuller, A. J. M., 2018, In : Acta Neuropathologica Communinications. 6, 1, p. 46Research output: Contribution to journal › Article › Academic › peer-review
Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody
Zhang, H., Zhu, X., Pascual, G., Wadia, J. S., Keogh, E., Hoozemans, J. J., Siregar, B., Inganäs, H., Stoop, E. J. M., Goudsmit, J., Apetri, A., Koudstaal, W. & Wilson, I. A., 2018, In : Structure. 26, 12, p. 1626-1634.e4Research output: Contribution to journal › Article › Academic › peer-review
Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease
Mercado, G., Castillo, V., Soto, P., López, N., Axten, J. M., Sardi, S. P., Hoozemans, J. J. M. & Hetz, C., 1 Apr 2018, In : Neurobiology of Disease. 112, p. 136-148 13 p.Research output: Contribution to journal › Article › Academic › peer-review
The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ42 and Alzheimer Amyloid Plaques
Dolfe, L., Tambaro, S., Tigro, H., Del Campo, M., Hoozemans, J. J. M., Wiehager, B., Graff, C., Winblad, B., Ankarcrona, M., Kaldmäe, M., Teunissen, C. E., Rönnbäck, A., Johansson, J. & Presto, J., 16 Feb 2018, In : Alzheimers & Dementia. 2, 1, p. 27-39 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Alpha-Synuclein Induces the Unfolded Protein Response in Parkinson's Disease SNCA Triplication iPSC-Derived Neurons
Heman-Ackah, S. M., Manzano, R., Hoozemans, J. J. M., Scheper, W., Flynn, R., Haerty, W., Cowley, S. A., Bassett, A. R. & Wood, M. J. A., 1 Jan 2017, In : Human Molecular Genetics. 26, 22, p. 4441-4450 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Altered Sphingolipid Balance in Capillary Cerebral Amyloid Angiopathy
de Wit, N. M., Snkhchyan, H., den Hoedt, S., Wattimena, D., de Vos, R., Mulder, M. T., Walter, J., Martinez-Martinez, P., Hoozemans, J. J., Rozemuller, A. J. & de Vries, H. E., 2017, In : Journal of Alzheimer's Disease. 60, 3, p. 795-807 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Distribution of tau pathology and neuroinflammation in typical versus atypical non-amnestic Alzheimer's disease
Boon, B. D. C., Hoozemans, J. J. M., van de Berg, W. D. J., Voorn, P., Scheltens, P., Rozemuller, J. M. & Bouwman, F. H., Feb 2017, In : Neuropathology and Applied Neurobiology. 43, p. 40-41Research output: Contribution to journal › Meeting Abstract › Academic
Immunological memory to hyperphosphorylated tau in asymptomatic individuals
Pascual, G., Wadia, J. S., Zhu, X., Keogh, E., Kükrer, B., van Ameijde, J., Inganäs, H., Siregar, B., Perdok, G., Diefenbach, O., Nahar, T., Sprengers, I., Koldijk, M. H., der Linden, E. C. B. V., Peferoen, L. A., Zhang, H., Yu, W., Li, X., Wagner, M., Moreno, V. & 16 others , 1 May 2017, In : Acta Neuropathologica. 133, 5, p. 767-783 17 p.Research output: Contribution to journal › Article › Academic › peer-review
Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation
van der Harg, J. M., Eggels, L., Bangel, F. N., Ruigrok, S. R., Zwart, R., Hoozemans, J. J. M., la Fleur, S. E. & Scheper, W., Jul 2017, In : Neurobiology of Disease. 103, p. 163-173 11 p.Research output: Contribution to journal › Article › Academic › peer-review
IRE1 signaling exacerbates Alzheimer's disease pathogenesis
Duran-Aniotz, C., Cornejo, V. H., Espinoza, S., Ardiles, Á. O., Medinas, D. B., Salazar, C., Foley, A., Gajardo, I., Thielen, P., Iwawaki, T., Scheper, W., Soto, C., Palacios, A. G., Hoozemans, J. J. M. & Hetz, C., 1 Sep 2017, In : Acta Neuropathologica. 134, 3, p. 489-506 18 p.Research output: Contribution to journal › Article › Academic › peer-review
Neuropathological assessment of cognitively healthy centenarians - The 100-Plus Study
Ganz, A. B., de Reus, M. A., Smit, A. B., Scheltens, P., Rozemuller, A., Hoozemans, J. J. M. & Holstege, H., Feb 2017, In : Neuropathology and Applied Neurobiology. 43, p. 14-15Research output: Contribution to journal › Meeting Abstract › Academic
Selective vulnerability of Von Economo Neurons and related neurons in C9orf72 bvFTD
Gami-Patel, P., Pijnenburg, Y. A. L., van Swieten, J. C., Rozemuller, A. J. M., Hoozemans, J. J. M. & Dijkstra, A., Feb 2017, In : Neuropathology and Applied Neurobiology. 43, p. 51-52Research output: Contribution to journal › Article › Academic › peer-review
Tau-positive nuclear indentations in P301S tauopathy mice
Fernández-Nogales, M., Santos-Galindo, M., Merchán-Rubira, J., Hoozemans, J. J. M., Rábano, A., Ferrer, I., Avila, J., Hernández, F. & Lucas, J. J., May 2017, In : Brain Pathology. 27, 3, p. 314-322 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Therapeutic potential of autophagy-enhancing agents in Parkinson's disease
Moors, T. E., Hoozemans, J. J. M., Ingrassia, A., Beccari, T., Parnetti, L., Chartier-Harlin, M. C. & Van De Berg, W. D. J., 25 Jan 2017, In : MOLECULAR NEURODEGENERATION. 12, 1, 11.Research output: Contribution to journal › Review article › Academic › peer-review
Unfolded protein response activation in C9orf72 FTD cases
Hoozemans, J. J. M., van Dijken, I., Meeter, L. H., Mel-Hem, S., van Swieten, J. C. & Rozemuller, J. M., Feb 2017, In : Neuropathology and Applied Neurobiology. 43, p. 15-16Research output: Contribution to journal › Article › Academic › peer-review
Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology
Wiersma, V. I., van Hecke, W., Scheper, W., van Osch, M. A. J., Hermsen, W. J. M., Rozemuller, A. J. M. & Hoozemans, J. J. M., 28 Oct 2016, In : Acta Neuropathologica Communinications. 4, 113.Research output: Contribution to journal › Article › Academic › peer-review
Activation of the unfolded protein response is not a common feature in human prion disease
Hoozemans, J. J. M., Wiersma, V. I., van Hecke, W., Scheper, W. & Rozemuller, J. M., Mar 2016, In : Neuropathology and Applied Neurobiology. 42, p. 29-30Research output: Contribution to journal › Meeting Abstract › Other research output
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., Adhihetty, P. J., Adler, S. G., Agam, G., Agarwal, R., Aghi, M. K., Agnello, M., Agostinis, P., Aguilar, P. V., Aguirre-Ghiso, J., Airoldi, E. M. & 2,447 others , 2016, In : Autophagy. 12, 1, p. 1-222Research output: Contribution to journal › Article › Academic › peer-review
Increased occurrence of protein kinase CK2 in astrocytes in Alzheimer's disease pathology
Rosenberger, A. F. N., Morrema, T. H. J., Gerritsen, W. H., van Haastert, E. S., Snkhchyan, H., Hilhorst, R., Rozemuller, A. J. M., Scheltens, P., van der Vies, S. M. & Hoozemans, J. J. M., 6 Jan 2016, In : Journal of Neuroinflammation. 13, 4.Research output: Contribution to journal › Article › Academic › peer-review
Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease
Hondius, D. C., van Nierop, P., Li, K. W., Hoozemans, J. J. M., van der Schors, R. C., van Haastert, E. S., van der Vies, S. M., Rozemuller, A. J. M. & Smit, A. B., Jun 2016, In : Alzheimers & Dementia. 12, 6, p. 654-668Research output: Contribution to journal › Article › Academic › peer-review
Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology
Rosenberger, A. F. N., Hilhorst, R., Coart, E., Garcia Barrado, L., Naji, F., Rozemuller, A. J. M., van der Flier, W. M., Scheltens, P., Hoozemans, J. J. M. & van der Vies, S. M., 2016, In : Journal of Alzheimer's Disease. 49, 4, p. 927-943Research output: Contribution to journal › Article › Academic › peer-review
The role of protein kinases in Alzheimer's disease
Rosenberger, A. F. N., 2016Research output: Thesis › Research VU University Amsterdam, graduation VU University Amsterdam › Academic
THE ROLE OF PROTEIN KINASES IN ALZHEIMER’S DISEASE
Rosenberger, A. & Hoozemans, JJM., 18 Nov 2016Research output: Thesis › Research VU University Amsterdam, graduation VU University Amsterdam › Academic
BRI2 ectodomain affects Aβ42 fibrillation and tau truncation in human neuroblastoma cells.
Del Campo Milan, M., Oliveira, C. R., Scheper, W., Zwart, R., Korth, C., Muller-Schiffmann, A., Kostallas, G., Biverstal, H., Presto, J., Johansson, J., Hoozemans, J. J., Pereira, C. F. & Teunissen, C. E., 2015, In : Cellular and Molecular Life Sciences. 72, 8, p. 1599-1611Research output: Contribution to journal › Article › Academic › peer-review
Neuroinflammation is not a Prerequisite for Diabetes-induced Tau Phosphorylation.
van der Harg, J. M., Eggels, L., Ruigrok, S. R., Hoozemans, J. J., la Fleur, S. E. & Scheper, W., 2015, In : Frontiers in Neuroscience. 9, 432.Research output: Contribution to journal › Article › Academic › peer-review
Physiological and pathophysiological functions of cell cycle proteins in post-mitotic neurons: implications for Alzheimer's disease
van Leeuwen, L. A. G. & Hoozemans, J. J. M., 2015, In : Acta Neuropathologica. 129, 4, p. 511-525Research output: Contribution to journal › Article › Academic › peer-review
The unfolded protein response in neurodegenerative diseases: a neuropathological perspective.
Scheper, W. & Hoozemans, J. J., 2015, In : Acta Neuropathologica. 130, 3, p. 315-331Research output: Contribution to journal › Article › Academic › peer-review
Altered distribution of the EphA4 kinase in hippocampal brain tissue of patients with Alzheimer's disease correlates with pathology
Rosenberger, A., Rozemuller, A. J. M., van der Flier, W. M., Scheltens, P., van der Vies, S. M. & Hoozemans, J. J. M., 2014, In : Acta Neuropathologica Communinications. 2, 79.Research output: Contribution to journal › Article › Academic › peer-review
Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases
Lim, J. L., Wilhelmus, M. M. M., de Vries, H. E., Drukarch, B., Hoozemans, J. J. M. & van Horssen, J., 2014, In : Archives of Toxicology. 88, 10, p. 1773-1786Research output: Contribution to journal › Article › Academic › peer-review
ATP-binding cassette transporters P-glycoprotein and breast cancer related protein are reduced in capillary cerebral amyloid angiopathy
Carrano, A., Snkhchyan, H., Kooij, G., van der Pol, S., van Horssen, J., Veerhuis, R., Hoozemans, J. J. M., Rozemuller, A. J. M. & de Vries, H. E., 2014, In : Neurobiology of Aging. 35, 3, p. 565-575Research output: Contribution to journal › Article › Academic › peer-review