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Research Output 1998 2019

Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology

Rosenberger, A. F. N., Hilhorst, R., Coart, E., Garcia Barrado, L., Naji, F., Rozemuller, A. J. M., van der Flier, W. M., Scheltens, P., Hoozemans, J. J. M. & van der Vies, S. M., 2016, In : Journal of Alzheimer's Disease. 49, 4, p. 927-943

Research output: Contribution to journalArticleAcademicpeer-review

Protein Kinase Activity Profiling of Postmortem Human Brain Tissue

Hoozemans, J. J. M., Hilhorst, R., Ruitenbeek, R., Rozemuller, J. M. & van der Vies, S. M., 2012, In : Neurodegenerative Diseases. 10, 1-4, p. 46-48

Research output: Contribution to journalArticleAcademicpeer-review

Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer's disease

Hondius, D. C., Eigenhuis, K. N., Morrema, T. H. J., van der Schors, R. C., van Nierop, P., Bugiani, M., Li, K. W., Hoozemans, J. J. M., Smit, A. B. & Rozemuller, A. J. M., 2018, In : Acta Neuropathologica Communinications. 6, 1, p. 46

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Quantification of amyloid-beta 40 in cerebrospinal fluid

Verwey, N. A., Veerhuis, R., Twaalfhoven, H. A. M., Wouters, D., Hoozemans, J. J. M., Bollen, Y. J. M., Killestein, J., Bibl, M., Wiltfang, J., Hack, C. E., Scheltens, P. & Blankenstein, M. A., 2009, In : Journal of Immunological Methods. 348, 1-2, p. 57-66

Research output: Contribution to journalArticleAcademicpeer-review

Rab6 is increased in Alzheimer's disease brain and correlates with endoplasmic reticulum stress

Scheper, W., Hoozemans, J. J. M., Hoogenraad, C. C., Rozemuller, A. J. M., Eikelenboom, P. & Baas, F., Oct 2007, In : Neuropathology and Applied Neurobiology. 33, 5, p. 523-32 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Removing protein aggregates: the role of proteolysis in neurodegeneration

Nijholt, D. A. T., de Kimpe, L., Elfrink, H. L., Hoozemans, J. J. M. & Scheper, W., 2011, In : Current Medicinal Chemistry. 18, 16, p. 2459-2476

Research output: Contribution to journalArticleAcademicpeer-review

25 Downloads (Pure)

Stages of granulovacuolar degeneration: their relation to Alzheimer's disease and chronic stress response

Thal, D. R., Del Tredici, K., Ludolph, A. C., Hoozemans, J. J. M., Rozemuller, J. M., Braak, H. & Knippschild, U., 2011, In : Acta Neuropathologica. 122, 5, p. 577-589

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody

Zhang, H., Zhu, X., Pascual, G., Wadia, J. S., Keogh, E., Hoozemans, J. J., Siregar, B., Inganäs, H., Stoop, E. J. M., Goudsmit, J., Apetri, A., Koudstaal, W. & Wilson, I. A., 2018, In : Structure. 26, 12, p. 1626-1634.e4

Research output: Contribution to journalArticleAcademicpeer-review

Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease

Mercado, G., Castillo, V., Soto, P., López, N., Axten, J. M., Sardi, S. P., Hoozemans, J. J. M. & Hetz, C., 1 Apr 2018, In : Neurobiology of Disease. 112, p. 136-148 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tau-positive nuclear indentations in P301S tauopathy mice

Fernández-Nogales, M., Santos-Galindo, M., Merchán-Rubira, J., Hoozemans, J. J. M., Rábano, A., Ferrer, I., Avila, J., Hernández, F. & Lucas, J. J., May 2017, In : Brain Pathology. 27, 3, p. 314-322 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The Activation of Microglia as an Early Sign of Disease Progression in Alzheimer's Disease

Veerhuis, R., Hoozemans, J. J. M., Cagnin, A., Eikelenboom, P. & Banati, R. B., 1 Sep 2013, Neuroglia. The Oxford University Press

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ42 and Alzheimer Amyloid Plaques

Dolfe, L., Tambaro, S., Tigro, H., Del Campo, M., Hoozemans, J. J. M., Wiehager, B., Graff, C., Winblad, B., Ankarcrona, M., Kaldmäe, M., Teunissen, C. E., Rönnbäck, A., Johansson, J. & Presto, J., 16 Feb 2018, In : Alzheimers & Dementia. 2, 1, p. 27-39 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The involvement of aβ in the neuroinflammatory response

Eikelenboom, P., Van Gool, W. A., Rozemuller, A. J. M., Scheper, W., Veerhuis, R. & Hoozemans, J. J. M., 1 Dec 2007, Abeta Peptide and Alzheimer's Disease: Celebrating a Century of Research. Springer London, p. 52-82 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

The nature of the cell cycle in neurons: focus on a "non-canonical" pathway of DNA replication causally related to death

Copani, A., Caraci, F., Hoozemans, J. J. M., Calafiore, M., Sortino, M. A. & Nicoletti, F., Apr 2007, In : Biochimica et Biophysica Acta. Reviews on Cancer. 1772, 4, p. 409-12 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

The pathological cascade of Alzheimer's disease: The role of inflammation and its therapeutic implications

Hoozemans, JJM., Veerhuis, R., Rozemuller, AJM. & Eikelenboom, P., Jun 2002, In : Drugs of Today. 38, 6, p. 429-443

Research output: Contribution to journalArticleAcademicpeer-review

Therapeutic potential of autophagy-enhancing agents in Parkinson's disease

Moors, T. E., Hoozemans, J. J. M., Ingrassia, A., Beccari, T., Parnetti, L., Chartier-Harlin, M. C. & Van De Berg, W. D. J., 25 Jan 2017, In : MOLECULAR NEURODEGENERATION. 12, 1, 11.

Research output: Contribution to journalReview articleAcademicpeer-review

The role of COX-1 and COX-2 in Alzheimer's disease pathology and the therapeutic potentials of non-steroidal anti-inflammatory drugs

Hoozemans, J. J. M. & O'Banion, M. K., 1 Jun 2005, In : Current Drug Targets: CNS and Neurological Disorders. 4, 3, p. 307-315 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

The role of cyclo-oxygenase 1 and 2 activity in prostaglandin E2 secretion by cultured human adult microglia: Implications for Alzheimer's disease

Hoozemans, J. J. M., Veerhuis, R., Janssen, I., Van Elk, E. J., Rozemuller, A. J. M. & Eikelenboom, P., 4 Oct 2002, In : Brain Research. 951, 2, p. 218-226 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The role of cyclo-oxygenase 1 and 2 activity in prostaglandin E-2 secretion by cultured human adult microglia: Implications for Alzheimer's disease

Hoozemans, JJM., Veerhuis, R., Janssen, I., van Elk, EJ., Rozemuller, AJM. & Eikelenboom, P., 4 Oct 2002, In : Brain Research. 951, 2, p. 218-226

Research output: Contribution to journalArticleAcademicpeer-review

The role of protein kinases in Alzheimer's disease

Rosenberger, A. F. N., 2016

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

THE ROLE OF PROTEIN KINASES IN ALZHEIMER’S DISEASE

Rosenberger, A. & Hoozemans, JJM., 18 Nov 2016

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

The significance of neuroinflammation in understanding Alzheimer's disease

Eikelenboom, P., Veerhuis, R., Scheper, W., Rozemuller, A. J. M., van Gool, W. A. & Hoozemans, J. J. M., Nov 2006, In : Journal of Neural Transmission. 113, 11, p. 1685-95 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

The unfolded protein response. A common pathomechanism in tauopathies

Nijholt, A. T., 2012, Oisterwijk: BOXPress.

Research output: ThesisResearch external, graduation externalAcademic

The unfolded protein response and proteostasis in Alzheimer disease: preferential activation of autophagy by endoplasmic reticulum stress

Scheper, W., Nijholt, D. A. T. & Hoozemans, J. J. M., Aug 2011, In : Autophagy. 7, 8, p. 910-911 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

The unfolded protein response in neurodegenerative diseases: a neuropathological perspective.

Scheper, W. & Hoozemans, J. J., 2015, In : Acta Neuropathologica. 130, 3, p. 315-331

Research output: Contribution to journalArticleAcademicpeer-review

The unfolded protein response is activated in Alzheimer's disease

Hoozemans, JJM., Veerhuis, R., Van Haastert, ES., Rozemuller, JM., Baas, F., Eikelenboom, P. & Scheper, W., Aug 2005, In : Acta Neuropathologica. 110, 2, p. 165-172

Research output: Contribution to journalArticleAcademicpeer-review

The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

Hoozemans, J. J. M., van Haastert, E. S., Nijholt, D. A. T., Rozemuller, A. J. M., Eikelenboom, P. & Scheper, W., 2009, In : The American Journal of Pathology. 174, 4, p. 1241-1251

Research output: Contribution to journalArticleAcademicpeer-review

The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies

Nijholt, D. A. T., van Haastert, E. S., Rozemuller, J. M., Scheper, W. & Hoozemans, J. J. M., 2012, In : Journal of Pathology. 226, 5, p. 693-702

Research output: Contribution to journalArticleAcademicpeer-review

The unfolded protein response mediates reversible tau phosphorylation induced by metabolic stress

van der Harg, J. M., Nölle, A., Zwart, R., Boerema, A. S., van Haastert, E. S., Strijkstra, A. M., Hoozemans, J. J. M. & Scheper, W., 2014, In : Cell death & disease. 28, 5, p. e1393 e1393.

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Transglutaminase Locates to ER in Parkinson's Disease: A Novel Mechanism Linking Neuronal Stress to Protein Aggregation?

Wilhelmus, M., Verhaar, R., Bol, J., Jongenelen, C., Andringa, G., Cras, P., Hoozemans, J. & Drukarch, B., 15 Sep 2010, In : Movement Disorders. 25, p. S630-S630

Research output: Contribution to journalArticleAcademicpeer-review

Ubiquilin 2 is not associated with tau pathology

Nolle, A., van Haastert, E. S., Zwart, R., Hoozemans, J. J. M. & Scheper, W., 2013, In : PLoS ONE. 8, 9, p. e76598 e76598.

Research output: Contribution to journalArticleAcademicpeer-review

Unfolded protein response activates glycogen synthase kinase-3 via selective lysosomal degradation

Nijholt, D. A. T., Nolle, A., van Haastert, E. S., Edelijn, H., Toonen, R. F. G., Hoozemans, J. J. M. & Scheper, W., 2013, In : Neurobiology of Aging. 34, 7, p. 1759-1771

Research output: Contribution to journalArticleAcademicpeer-review

Unfolded protein response activation in C9orf72 FTD cases

Hoozemans, J. J. M., van Dijken, I., Meeter, L. H., Mel-Hem, S., van Swieten, J. C. & Rozemuller, J. M., Feb 2017, In : Neuropathology and Applied Neurobiology. 43, p. 15-16

Research output: Contribution to journalArticleAcademicpeer-review

Von Economo neurons are part of a larger neuronal population that are selectively vulnerable in C9orf72 frontotemporal dementia

Netherlands Brain Bank, 2019, In : Neuropathology and Applied Neurobiology.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
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