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Research Output 2001 2019

Acid sphingomyelinase: No potential as a biomarker for multiple sclerosis

Leurs, C. E., Lopes Pinheiro, M. A., Wierts, L., den Hoedt, S., Mulder, M. T., Eijlers, A. J. C., Schoonheim, M. M., Balk, L. J., Uitdehaag, B. M. J., Killestein, J. & de Vries, H. E., 1 Feb 2019, In : Multiple Sclerosis and Related Disorders. 28, p. 44-49 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Anti-natalizumab antibodies during 8 years of natalizumab treatment: effect on natalizumab concentration and α4-integrin receptor saturation

van Kempen, Z. L. E., van Rossum, J. A., Doesburg, D., Claessen, I., de Vries, A., ten Brinke, A., van Oosten, B. W., Rispens, T. & Killestein, J., 2019, In : Journal of Neurology. 266, 7, p. 1804-1805

Research output: Contribution to journalComment/Letter to the editorAcademic

Dimethyl fumarate-induced changes in the MS lymphocyte repertoire: No need for subset monitoring

Killestein, J. & Reder, A. T., 2019, In : Neurology. 92, 15, p. 696-697

Research output: Contribution to journalEditorialAcademicpeer-review

Emerging safety issues in alemtuzumab-treated MS patients

Killestein, J. & van Oosten, B., 2019, In : Multiple Sclerosis Journal. 25, 9, p. 1206-1208

Research output: Contribution to journalEditorialAcademicpeer-review

Gray matter networks and cognitive impairment in multiple sclerosis

Rimkus, C. M., Schoonheim, M. M., Steenwijk, M. D., Vrenken, H., Eijlers, A. J., Killestein, J., Wattjes, M. P., Leite, C. C., Barkhof, F. & Tijms, B. M., 1 Mar 2019, In : Multiple Sclerosis. 25, 3, p. 382-391

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Kappa free light chains is a valid tool in the diagnostics of MS: A large multicenter study

Leurs, C. E., Twaalfhoven, H. A. M., Lissenberg-Witte, B. I., van Pesch, V., Dujmovic, I., Drulovic, J., Castellazzi, M., Bellini, T., Pugliatti, M., Kuhle, J., Villar, L. M., Alvarez-Cermeño, J. C., Alvarez-Lafuente, R., Hegen, H., Deisenhammer, F., Walchhofer, L. M., Thouvenot, E., Comabella, M., Montalban, X., Vécsei, L. & 19 othersRajda, C., Galimberti, D., Scarpini, E., Altintas, A., Rejdak, K., Frederiksen, J. L., Pihl-Jensen, G., Jensen, P. E. H., Khalil, M., Voortman, M. M., Fazekas, F., Saiz, A., la Puma, D., Vercammen, M., Vanopdenbosch, L., Uitdehaag, B. M. J., Killestein, J., Bridel, C. & Teunissen, C., 2019, In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Novel imaging markers for neuroinflammation in multiple sclerosis

Hagens, MHJ., 6 Dec 2019, 157 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

Pharmacodynamic assessment of cell-bound natalizumab on PBMC samples stored in liquid nitrogen

ten Brinke, A., Claessen, I., van Kempen, Z. L. E., Killestein, J. & Rispens, T., 2019, In : Journal of Immunological Methods. 473

Research output: Contribution to journalArticleAcademicpeer-review

Plasma proteome in multiple sclerosis disease progression

Malekzadeh, A., Leurs, C., van Wieringen, W., Steenwijk, M. D., Schoonheim, M. M., Amann, M., Naegelin, Y., Kuhle, J., Killestein, J. & Teunissen, C. E., 2019, In : Annals of Clinical and Translational Neurology. 6, 9, p. 1582-1594

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The natalizumab wearing-off effect: End of natalizumab cycle, recurrence of MS symptoms

van Kempen, Z. L. E., Doesburg, D., Dekker, I., Lissenberg-Witte, B. I., de Vries, A., Claessen, I. A., Brinke, A. T., Rispens, T. & Killestein, J., 22 Oct 2019, In : Neurology. 93, 17, p. e1579-e1586

Research output: Contribution to journalArticleAcademicpeer-review

The role of MRI in pharmacovigilance of natalizumab-treated MS patients: a "known unknown"?

Wattjes, MP., 3 Jun 2019

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

Open Access
2018

Acute syphilitic meningitis in an HIV-infected patient

Wagemakers, A., Hepp, D., Killestein, J., Peferoen, L. & Ang, W., 2018, In : IDCases. 13, e00423.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Asymptomatic spinal cord lesions do not predict the time to disability in patients with early multiple sclerosis.

Dekker, I., Klieverik-Sombekke, MH., Witte, BI., Geurts, JJG., Barkhof, F., Uitdehaag, BMJ., Killestein, J. & Wattjes, MP., 1 Apr 2018, In : Multiple Sclerosis. 24, 4, p. 481-490

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment

Leurs, C. E., Podlesniy, P., Trullas, R., Balk, L., Steenwijk, M. D., Malekzadeh, A., Piehl, F., Uitdehaag, B. M., Killestein, J., van Horssen, J. & Teunissen, C. E., 1 Apr 2018, In : Multiple Sclerosis. 24, 4, p. 472-480 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Deep gray matter volume loss drives disability worsening in multiple sclerosis

Eshaghi, A., Prados, F., Brownlee, W. J., Altmann, D. R., Tur, C., Cardoso, M. J., De Angelis, F., van de Pavert, S. H., Cawley, N., De Stefano, N., Stromillo, M. L., Battaglini, M., Ruggieri, S., Gasperini, C., Filippi, M., Rocca, M. A., Rovira, A., Sastre-Garriga, J., Vrenken, H., Leurs, C. E. & 11 othersKillestein, J., Pirpamer, L., Enzinger, C., Ourselin, S., Wheeler-Kingshott, C. A. M. G., Chard, D., Thompson, A. J., Alexander, D. C., Barkhof, F., Ciccarelli, O. & on behalf of the MAGNIMS study group, 1 Feb 2018, In : Annals of Neurology. 83, 2, p. 210-222 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effects on Spasticity and Neuropathic Pain of an Oral Formulation of δ9-Tetrahydrocannabinol in Patients With Progressive Multiple Sclerosis

van Amerongen, G., Kanhai, K., Baakman, A. C., Heuberger, J., Klaassen, E., Beumer, T. L., Strijers, R. L. M., Killestein, J., van Gerven, J., Cohen, A. & Groeneveld, G. J., 1 Sep 2018, In : Clinical Therapeutics. 40, 9, p. 1467-1482 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

gMS-Classifier1 does not predict disability progression in multiple sclerosis

van Rossum, J. A., Killestein, J., Villar, L. M., Riskind, P. N., Freedman, M. S. & Teunissen, C., 2018, In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticleAcademicpeer-review

High reproducibility and robustness to lesions, but large software and scanner effects for mean upper cervical cord area (MUCCA) measurement in MS

Middelkoop, S., Weeda, M. M., Steenwijk, M. D., Daams, M., Amiri, H., Brouwer, I., Killestein, J., Uitdehaag, B. M. J., Dekker, I., Lukas, C., Bellenberg, B., Barkhof, F., Pouwels, P. J. W. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 853-854

Research output: Contribution to journalMeeting AbstractAcademic

High reproducibility and robustness to lesions, but large software and scanner effects for mean upper cervical cord area (MUCCA) measurement in MS

Weeda, MM., Middelkoop, SM., Steenwijk, MD., Daams, M., Amiri Doumari, H., Brouwer, I., Killestein, J., Uitdehaag, BMJ., Dekker, I., Lukas, C., Bellenberg, B., Barkhof, F., Pouwels, PJW. & Vrenken, H., 6 Nov 2018, (Submitted).

Research output: Contribution to conferenceAbstractAcademic

Imaging of meningeal inflammation should become part of the routine MRI protocol – No

Wattjes, M. P. & Killestein, J., 2018, In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticleAcademicpeer-review

Impact of 3 Tesla MRI on interobserver agreement in clinically isolated syndrome: A MAGNIMS multicentre study

Hagens, M. H., Burggraaff, J., Kilsdonk, I. D., Ruggieri, S., Collorone, S., Cortese, R., Cawley, N., Sbardella, E., Andelova, M., Amann, M., Lieb, J. M., Pantano, P., Lissenberg-Witte, B. I., Killestein, J., Oreja-Guevara, C., Wuerfel, J., Ciccarelli, O., Gasperini, C., Lukas, C., Rovira, A. & 3 othersBarkhof, F., Wattjes, M. P. & MAGNIMS Study Group, Mar 2018, In : Multiple Sclerosis. 25, 3, p. 352-360

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Inflammatory natalizumab-associated PML: baseline characteristics, lesion evolution and relation with PML-IRIS

Wattjes, M. P., Wijburg, M. T., Eijk, J. V., Frequin, S., Uitdehaag, B. M. J., Barkhof, F., Warnke, C., Killestein, J. & the Dutch-Belgian Natalizumab-Associated PML Study Group, May 2018, In : Journal of Neurology, Neurosurgery and Psychiatry. 89, 5, p. 535-541

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Information processing speed in multiple sclerosis: Relevance of default mode network dynamics

van Geest, Q., Douw, L., van ‘t Klooster, S., Leurs, C. E., Genova, H. M., Wylie, G. R., Steenwijk, M. D., Killestein, J., Geurts, J. J. G. & Hulst, H. E., 2018, In : NeuroImage: Clinical. 19, p. 507-515

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Reliability of cross-sectional and longitudinal brain volume measurements in MS patients using FreeSurfer: a multi-vendor MRI study at 3 Tesla

Amiri, H., Renckens, S., Brouwer, I., Bosschaert, S., van Tuijl, R., Hagens, M., Killestein, J., Barkhof, F. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 515-515

Research output: Contribution to journalMeeting AbstractAcademic

Open Access