20032020

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A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17(+) cell frequency

Punt, S., Dronkers, E. A. C., Welters, M. J. P., Goedemans, R., Koljenovic, S., Bloemena, E., Snijders, P. J. F., Gorter, A., van der Burg, S. H., de Jong, R. J. B. & Jordanova, E. S., Apr 2016, In : Cancer Immunology and Immunotherapy. 65, 4, p. 393-403

Research output: Contribution to journalArticleAcademicpeer-review

Alloreactive Effector T Cells Require the Local Formation of a Proinflammatory Environment to Allow Crosstalk and High Avidity Interaction with Nonhematopoietic Tissues to Induce GVHD Reactivity

van der Zouwen, B., Kruisselbrink, A. B., Jordanova, E. S., Rutten, C. E., von dem Borne, P. A., Falkenburg, J. & Jedema, I., 2012, In : Biology of Blood and Marrow Transplantation. 18, 9, p. 1353-1367

Research output: Contribution to journalArticleAcademicpeer-review

A Murine Model for Metastatic Conjunctival Melanoma

de Waard, N. E., Cao, J. F., McGuire, S. P., Kolovou, P. E., Jordanova, E. S., Ksander, B. R. & Jager, M. J., 2015, In : Investigative Ophthalmology and Visual Science. 56, 4, p. 2325-2333

Research output: Contribution to journalArticleAcademicpeer-review

Autocrine expression of the epidermal growth factor receptor ligand heparin-binding EGF-like growth factor in cervical cancer

Schrevel, M., Osse, E. M., Prins, F. A., Trimbos, J. B. M. Z., Fleuren, G. J., Gorter, A. & Jordanova, E. S., Jun 2017, In : International Journal of Oncology. 50, 6, p. 1947-1954 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Blocking tumor-educated MSC paracrine activity halts osteosarcoma progression

Baglio, S. R., Lagerweij, T., Pérez-Lanzón, M., Ho, X. D., Léveillé, N., Melo, S. A., Cleton-Jansen, A. M., Jordanova, E. S., Roncuzzi, L., Greco, M., Van Eijndhoven, M. A. J., Grisendi, G., Dominici, M., Bonafede, R., Lougheed, S. M., De Gruijl, T. D., Zini, N., Cervo, S., Steffan, A., Canzonieri, V. & 6 others, Martson, A., Maasalu, K., Köks, S., Wurdinger, T., Baldini, N. & Pegtel, D. M., 15 Jul 2017, In : Clinical Cancer Research. 23, 14, p. 3721-3733 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cancer immunophenotyping by 7 colour multispectral imaging without tyramide signal amplification

Ijselstein, M., Brouwer, T., Abdulrahman, Z., Reidy, E., Ramalheiro, A., Heeren, AM., Vahrmeijer, A., Jordanova, ES. & de Miranda, N., Jan 2019, In : The Journal of Pathology: Clinical Research. 5, 1, p. 3-11

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cancer immunophenotyping by seven-colour multispectral imaging without tyramide signal amplification

Ijsselsteijn, M. E., Brouwer, T. P., Abdulrahman, Z., Reidy, E., Ramalheiro, A., Heeren, A. M., Vahrmeijer, A., Jordanova, E. S. & de Miranda, N. F., 1 Jan 2019, In : The journal of pathology. Clinical research. 5, 1, p. 3-11

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Chromosomal profiles of high-grade cervical intraepithelial neoplasia relate to duration of preceding high-risk human papillomavirus infection

Bierkens, M., Wilting, S. M., van Wieringen, W. N., van Kemenade, F. J., Bleeker, M. C. G., Jordanova, E. S., Bekker-Lettink, M., van de Wiel, M., Ylstra, B., Meijer, C. J. L. M., Snijders, P. J. F. & Steenbergen, R. D. M., 2012, In : International Journal of Cancer. 131, 4, p. E579-E585

Research output: Contribution to journalArticleAcademicpeer-review

Chromosome 5q Loss in Colorectal Flat Adenomas

Voorham, Q. J. M., Carvalho, B., Spiertz, A. J., van Grieken, N. C. T., Mongera, S., Rondagh, E. J. A., van de Wiel, M., Jordanova, E. S., Ylstra, B., Kliment, M., Grabsch, H., Rembacken, B. J., Arai, T., de Bruine, A. P., Sanduleanu, S., Quirke, P., Mulder, C. J. J., van Engeland, M. & Meijer, G. A., 2012, In : Clinical Cancer Research. 18, 17, p. 4560-4569

Research output: Contribution to journalArticleAcademicpeer-review

Classic and Nonclassic HLA Class I Expression in Penile Cancer and Relation to HPV Status and Clinical Outcome

Djajadiningrat, R. S., Horenblas, S., Heideman, D. A. M., Sanders, J., de Jong, J. & Jordanova, E. S., 2015, In : The Journal of Urology. 193, 4, p. 1245-1251

Research output: Contribution to journalArticleAcademicpeer-review

Clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome

Scholl, S., Popovic, M., de la Rochefordiere, A., Girard, E., Dureau, S., Mandic, A., Koprivsek, K., Samet, N., Craina, M., Margan, M., Samuels, S., Zijlmans, H., Kenter, G., Hillemanns, P., Dema, S., Dema, A., Malenkovic, G., Djuran, B., Floquet, A., Garbay, D. & 34 others, Guyon, F., Colombo, P. E., Fabbro, M., Kerr, C., Ngo, C., Lecuru, F., Campo, E. R. D., Coutant, C., Marchal, F., Mesgouez-Nebout, N., Fourchotte, V., Feron, J. G., Morice, P., Deutsch, E., Wimberger, P., Classe, J-M., Gleeson, N., von der Leyen, H., Minsat, M., Dubot, C., Gestraud, P., Kereszt, A., Nagy, I., Balint, B., Berns, E., Jordanova, E., Saint-Jorre, N. D., Savignoni, A., Servant, N., Hupe, P., de Koning, L., Fumoleau, P., Rouzier, R. & Kamal, M., 1 May 2019, In : EBioMedicine. 43, p. 253-260 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Correlations between immune response and vascularization qRT-PCR gene expression clusters in squamous cervical cancer

Punt, S., Houwing-Duistermaat, J. J., Schulkens, I. A. E., Thijssen, V. L. J. L., Osse, E. M., de Kroon, C. D., Griffioen, A. W., Fleuren, G. J., Gorter, A. & Jordanova, E. S., 2015, In : Molecular Cancer. 14, 71.

Research output: Contribution to journalArticleAcademicpeer-review

CXCR7 expression is associated with disease-free and disease-specific survival in cervical cancer patients

Schrevel, M., Karim, R., ter Haar, N., van der Burg, S., Trimbos, J., Fleuren, G., Gorter, A. & Jordanova, E. S., 2012, In : British Journal of Cancer. 106, 9, p. 1520-1525

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Cytomorphological Analysis of Uterine Cervical Pap Smears in Relation to Human Papillomavirus Infection in Indonesian Women

Rachmadi, L., Jordanova, E. S., Kolkman-Uljee, S., van der Linden-Narain, I., Purwoto, G., Siregar, B., Fleuren, G. J., Cornain, S. & Veselic, M., 2012, In : Acta Cytol. 56, 2, p. 171-176

Research output: Contribution to journalArticleAcademicpeer-review

Decidual infiltration of FoxP3(+) regulatory T cells, CD3(+) T cells, CD56(+) decidual natural killer cells and Ki-67 trophoblast cells in hydatidiform mole compared to normal and ectopic pregnancies

Sundara, Y. T., Jordanova, E. S., Hernowo, B. S., Gandamihardja, S. & Fleuren, G. J., 2012, In : Molecular Medicine Reports. 5, 1, p. 275-281

Research output: Contribution to journalArticleAcademicpeer-review

Different Subsets of Tumor-Infiltrating Lymphocytes Correlate with Macrophage Influx and Monosomy 3 in Uveal Melanoma

Bronkhorst, I. H. G., Vu, T. H. K., Jordanova, E. S., Luyten, G. P. M., van der Burg, S. H. & Jager, M. J., 2012, In : Investigative Ophthalmology and Visual Science. 53, 9, p. 5370-5378

Research output: Contribution to journalArticleAcademicpeer-review

Digital PCR-Based T-cell Quantification-Assisted Deconvolution of the Microenvironment Reveals that Activated Macrophages Drive Tumor Inflammation in Uveal Melanoma

de Lange, M. J., Nell, R. J., Lalai, R. N., Versluis, M., Jordanova, E. S., Luyten, G. P. M., Jager, M. J., van der Burg, S. H., Zoutman, W. H., van Hall, T. & van der Velden, P. A., Dec 2018, In : Molecular Cancer Research. 16, 12, p. 1902-1911 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

EMSY Links the BRCA2 Pathway to Sporadic Breast and Ovarian Cancer

Hughes-Davies, L., Huntsman, D., Ruas, M., Fuks, F., Bye, J., Chin, S. F., Milner, J., Brown, L. A., Hsu, F., Gilks, B., Nielsen, T., Schulzer, M., Chia, S., Ragaz, J., Cahn, A., Linger, L., Ozdag, H., Cattaneo, E., Jordanova, E. S., Schuuring, E. & 10 others, Yu, D. S., Venkitaraman, A., Ponder, B., Doherty, A., Aparicio, S., Bentley, D., Theillet, C., Ponting, C. P., Caldas, C. & Kouzarides, T., 26 Nov 2003, In : Cell. 115, 5, p. 523-535 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival

Van Esch, E. M. G., Van Poelgeest, M. I. E., Kouwenberg, S., Osse, E. M., Trimbos, J. B. M. Z., Fleuren, G. J., Jordanova, E. S. & Van Der Burg, S. H., 1 Jan 2016, In : International Journal of Cancer. 136, 4, p. E95-E106

Research output: Contribution to journalArticleAcademicpeer-review

Expression of Programmed Death Ligand 1 in Penile Cancer is of Prognostic Value and Associated with HPV Status

Ottenhof, S. R., Djajadiningrat, R. S., de Jong, J., Thygesen, H. H., Horenblas, S. & Jordanova, E. S., Mar 2017, In : The Journal of Urology. 197, 3, p. 690-696

Research output: Contribution to journalArticleAcademicpeer-review

FoxP3(+) and IL-17(+) cells are correlated with improved prognosis in cervical adenocarcinoma

Punt, S., van Vliet, M. E., Spaans, V. M., de Kroon, C. D., Fleuren, G. J., Gorter, A. & Jordanova, E. S., 2015, In : Cancer Immunology and Immunotherapy. 64, 6, p. 745-753

Research output: Contribution to journalArticleAcademicpeer-review

Frequent HLA class I loss is an early event in cervical carcinogenesis

Vermeulen, C. F. W., Jordanova, E. S., Zomerdijk-Nooijen, Y. A., Ter Haar, N. T., Peters, A. A. W. & Fleuren, G. J., 1 Nov 2005, In : Human Immunology. 66, 11, p. 1167-1173 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Galectin-1,-3 and-9 Expression and Clinical Significance in Squamous Cervical Cancer

Punt, S., Thijssen, V. L. J. L., Vrolijk, J., de Kroon, C. D., Gorter, A. & Jordanova, E. S., 2015, In : PLoS ONE. 10, 6, e0129119.

Research output: Contribution to journalArticleAcademicpeer-review

Genome Haploidisation with Chromosome 7 Retention in Oncocytic Follicular Thyroid Carcinoma

Corver, W. E., Ruano, D., Weijers, K., den Hartog, W. C. E., van Nieuwenhuizen, M. P., Miranda, N., van Eijk, R., Middeldorp, A., Jordanova, E. S., Oosting, J., Kapiteijn, E., Hovens, G., Smit, J., van Wezel, T. & Morreau, H., 2012, In : PLoS ONE. 7, 6, e38287.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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High levels of soluble MICA are significantly related to increased disease-free and disease-specific survival in patients with cervical adenocarcinoma

Samuels, S., Ferns, D. M., Meijer, D., van Straalen, J. P., Buist, M. R., Zijlmans, H. J. M. A. A., Kenter, G. G. & Jordanova, E. S., 2015, In : Tissue Antigens. 85, 6, p. 476-483

Research output: Contribution to journalArticleAcademicpeer-review

HLA class I antigen expression in conjunctival melanoma is not associated with PD-L1/PD-1 status

Cao, J., Brouwer, N. J., Jordanova, E. S., Marinkovic, M., Van Duinen, S. G., De Waard, N. E., Ksander, B. R., Mulder, A., Claas, F. H. J., Heemskerk, M. H. M. & Jager, M. J., 1 Feb 2018, In : Investigative Ophthalmology and Visual Science. 59, 2, p. 1005-1015 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

HLA class II expression on tumor cells and low numbers of tumor-associated macrophages predict clinical outcome in oropharyngeal cancer

Cioni, B., Jordanova, E. S., Hooijberg, E., van der Linden, R., de Menezes, R. X., Tan, K., Willems, S., Elbers, J. B. W., Broeks, A., Bergman, A. M., Zuur, C. L. & de Boer, J. P., 1 Feb 2019, In : Head and Neck. 41, 2, p. 463-478 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

HLA class II upregulation during viral infection leads to HLA-DP-directed graft-versus-host disease after CD4+donor lymphocyte infusion

Stevanovic, S., van Bergen, C. A. M., van Luxemburg-Heijs, S. A. P., van der Zouwen, B., Jordanova, E. S., Kruisselbrink, A. B., de Meent, M. V., Harskamp, J. C., Claas, F. H. J., Marijt, E. W. A., Zwaginga, JJ., Halkes, C. J. M., Jedema, I., Griffioen, M. & Falkenburg, J. H. F., 2013, In : Blood. 122, 11, p. 1963-1973

Research output: Contribution to journalArticleAcademicpeer-review

HLA-E expression in cervical adenocarcinomas: association with improved long-term survival

Spaans, V. M., Peters, A. A., Fleuren, G. J. & Jordanova, E. S., 2012, In : Journal of Translational Medicine. 10, 184.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
59 Downloads (Pure)

HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas

Rutten, M. J., Dijk, F., Savci-Heijink, C. D., Buist, M. R., Kenter, G. G., van de Vijver, M. J. & Jordanova, E. S., 2014, In : Journal of Immunology Research. 2014, 274584.

Research output: Contribution to journalArticleAcademicpeer-review

HPV16 E7 DNA tattooing: safety, immunogenicity, and clinical response in patients with HPV-positive vulvar intraepithelial neoplasia

Samuels, S., Marijne Heeren, A., Zijlmans, H. J. M. A. A., Welters, M. J. P., van den Berg, J. H., Philips, D., Kvistborg, P., Ehsan, I., Scholl, S. M. E., Nuijen, B., Schumacher, T. N. M., van Beurden, M., Jordanova, E. S., Haanen, J. B. A. G., van der Burg, S. H. & Kenter, G. G., 1 Sep 2017, In : Cancer Immunology, Immunotherapy. 66, 9, p. 1163-1173 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

HPV pathway profiling: HPV related cervical dysplasia and carcinoma studies

Scholl, S. M., Kamal, M., de Koning, L., Kereszt, A., Jordanova, E. S., Ungureanu, S., Berns, E. & Sastre, X., 2013, In : Current Pharmaceutical Design. 19, 8, p. 1379-1394

Research output: Contribution to journalArticleAcademicpeer-review

Human Leukocyte Antigen-DR Expression is Significantly Related to an Increased Disease-Free and Disease-Specific Survival in Patients With Cervical Adenocarcinoma

Samuels, S., Spaans, V. M., Osse, M., Peters, L. A. W., Kenter, G. G., Fleuren, G. J. & Jordanova, E. S., Oct 2016, In : International Journal of Gynecological Cancer. 26, 8, p. 1503-1509 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Human Papillomavirus Prevalence in Invasive Penile Cancer and Association with Clinical Outcome

Djajadiningrat, R. S., Jordanova, E. S., Kroon, B. K., van Werkhoven, E., de Jong, J., Pronk, D. T. M., Snijders, P. J. F., Horenblas, S. & Heideman, D. A. M., 2015, In : The Journal of Urology. 193, 2, p. 526-531

Research output: Contribution to journalArticleAcademicpeer-review

Human papillomavirus status in young patients with head and neck squamous cell carcinoma

van Monsjou, H., van Velthuysen, M., van den Brekel, M., Jordanova, E. S., Melief, C. & Balm, A., 2012, In : International Journal of Cancer. 130, 8, p. 1806-1812

Research output: Contribution to journalArticleAcademicpeer-review

Human papillomavirus type 16 E6, E7, and L1 variants in cervical cancer in Indonesia, Suriname, and the Netherlands

De Boer, M. A., Peters, L. A. W., Aziz, M. F., Siregar, B., Cornain, S., Vrede, M. A., Jordanova, E. S., Kolkman-Uljee, S. & Fleuren, G. J., 1 Aug 2004, In : Gynecologic Oncology. 94, 2, p. 488-494 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Immunological profiling of molecularly classified high-risk endometrial cancers identifies POLE-mutant and microsatellite unstable carcinomas as candidates for checkpoint inhibition

Eggink, F. A. A., Van Gool, I. C. B., Leary, A. C., Pollock, P. M. D., Crosbie, E. J. E., Mileshkin, L. F., Jordanova, E. S. B., Adam, J. C., Freeman-Mills, L. H., Church, D. N. H., Creutzberg, C. L. J., De Bruyn, M. A., Nijman, H. W. A. & Bosse, T. B., 2017, In : OncoImmunology. 6, 2

Research output: Contribution to journalArticleAcademicpeer-review

Independent validation of the prognostic significance of invasion patterns in endocervical adenocarcinoma: Pattern A predicts excellent survival

Spaans, V. M., Scheunhage, D. A., Barzaghi, B., de Kroon, C. D., Fleuren, G. J., Bosse, T. & Jordanova, E. S., Nov 2018, In : Gynecologic Oncology. 151, 2, p. 196-201 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Indoleamine-2,3-dioxygenase (IDO) metabolic activity is detrimental for cervical cancer patient survival

Ferns, D. M., Kema, I. P., Buist, M. R., Nijman, H. W., Kenter, G. G. & Jordanova, E. S., 2015, In : OncoImmunology. 4, 2, e981457.

Research output: Contribution to journalArticleAcademicpeer-review

Indoleamine 2,3-dioxygenase expression pattern in the tumor microenvironment predicts clinical outcome in early stage cervical cancer

Heeren, A. M., van Dijk, I., Berry, D. R. A. I., Khelil, M., Ferns, D., Kole, J., Musters, R. J. P., Thijssen, V. L., Mom, C. H., Kenter, G. G., Bleeker, M. C. G., de Gruijl, T. D. & Jordanova, E. S., 11 Jul 2018, In : Frontiers in Immunology. 9, JUL, 1598.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Infiltration of Lynch Colorectal Cancers by Activated Immune Cells Associates with Early Staging of the Primary Tumor and Absence of Lymph Node Metastases

de Miranda, N. F. C. C., Goudkade, D., Jordanova, E. S., Tops, C. M. J., Hes, F. J., Vasen, H. F. A., van Wezel, T. & Morreau, H., 2012, In : Clinical Cancer Research. 18, 5, p. 1237-1245

Research output: Contribution to journalArticleAcademicpeer-review

Interleukin-6 receptor and its ligand interleukin-6 are opposite markers for survival and infiltration with mature myeloid cells in ovarian cancer

Wouters, M. C. A., Dijkgraaf, E. M., Kuijjer, M. L., Jordanova, E. S., Hollema, H., Welters, M. J. P., van der Hoeven, JJM., Daemen, T., Kroep, J. R., Nijman, H. W. & van der Burg, S., 2014, In : OncoImmunology. 3, 12, e962397.

Research output: Contribution to journalArticleAcademicpeer-review