Research output per year
Research output per year
Personal profile
Research interests
Dr. Jonkman is an assistant professor at the department of Anatomy and Neurosciences at Amsterdam UMC - location VUmc. Her research focus is to translate post-mortem MRI signatures of neuropathology to the clinical setting.
Dr. Jonkman is developing herself as an expert on post-mortem MRI and pathology studies in neurodegenerative disease. In 2018 she received the Alzheimer Association Research Fellowship (AARF) to investigate the influence of histological markers on the AD structural network. In 2019 he received a Michael J Fox Foundation grant to study the relationship between MRI and pathology in Parkinson’s disease. With this and other funding, and several excellent collaborations, dr. Jonkman hopes to broaden the search for clinically relevant, pathology-specific imaging biomarkers in neurodegenerative disease.
Education/Academic qualification
PhD, Visualizing and Characterizing Tissue Abnormalities in Multiple Sclerosis, VUmc, Amsterdam, Netherlands
Award Date: 17 Feb 2016
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Normal Aging Brain Collection Amsterdam (NABCA): A comprehensive collection of postmortem high-field imaging, neuropathological and morphometric datasets of non-neurological controls
Jonkman, L. E., Graaf, Y. G., Bulk, M., Kaaij, E., Pouwels, P. J. W., Barkhof, F., Rozemuller, A. J. M., van der Weerd, L., Geurts, J. J. G. & van de Berg, W. D. J., 1 Jan 2019, In: NeuroImage: Clinical. 22, 101698.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Diffuse Amyloid-β relates to lower structural degree and higher local efficiency in the posterior cingulate cortex: a post-mortem MRI and histology study.
Jonkman, LE., Steenwijk, MD., Galis-de Graaf, Y., Rozemuller, AJM., Geurts, JJG., Barkhof, F. & van de Berg, WDJ., 2020, (Accepted/In press) In: Neurology.Research output: Contribution to journal › Article › Academic › peer-review
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Amyloid-β, p-tau and reactive microglia are pathological correlates of MRI cortical atrophy in Alzheimer's disease
Frigerio, I., Boon, B. D. C., Lin, C-P., Graaf, Y. G-D., Bol, J., Preziosa, P., Twisk, J., Barkhof, F., Hoozemans, J. J. M., Bouwman, F. H., Rozemuller, A. J. M., van de Berg, W. D. J. & Jonkman, L. E., 2021, In: Brain Communications. 3, 4, fcab281.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Artificial double inversion recovery images can substitute conventionally acquired images: an MRI-histology study
Bouman, P. M., Steenwijk, M. D., Geurts, J. J. G. & Jonkman, L. E., Dec 2022, In: Scientific Reports. 12, 1, p. 2620 2620.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Axonal degeneration in the anterior insular cortex is associated with Alzheimer's co-pathology in Parkinson's disease and dementia with Lewy bodies
Fathy, Y. Y., Jonkman, L. E., Bol, J. J., Timmermans, E., Jonker, A. J., Rozemuller, A. J. M. & van de Berg, W. D. J., 7 Dec 2022, In: Translational Neurodegeneration. 11, 1, p. 52 52.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Activities
- 1 Membership of board
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Anatomy and neurosciences (Organisational unit)
Wilma van de Berg (Chair), LE Jonkman (Member) & JJG Geurts (Member)
1 Jan 2014 → …Activity: Membership › Membership of board
Prizes
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A picture is worth a thousand words: telling the tale of the Parkinson brain with correlative postmortem MRI and microscopy.
van de Berg, Wilma (Recipient), Jonkman, Laura (Recipient), Berendse, Henk (Recipient) & van der Werf, Ysbrand (Recipient), 2019
Prize: Honorary award