Research output per year
Research output per year
Personal profile
Research interests
Dr. Jonkman is assistant professor at the Amsterdam UMC - location VUmc Clinical Neuroanatomy team. Her research focus is to translate post-mortem MRI signatures of neuropathology to the clinical setting. She currently supervises three PhD students.
Dr. Jonkman is developing herself as an expert on post-mortem MRI and pathology studies in neurodegenerative disease. She recently published on early MRI network markers of pathological change in Neurology journal. In 2018 she received the Alzheimer Association Research Fellowship (AARF) to investigate the influence of histological markers on the AD structural network. In 2019 he received a Michael J Fox Foundation grant (Co-PI) to study the relationship between MRI and pathology in Parkinson’s disease. With sevral excellent collaborations, she hopes to broaden the search for clinically relevant, pathology-specific imaging biomarkers in neurodegenerative disease.
Education/Academic qualification
PhD, VUmc, Amsterdam, Netherlands
Award Date: 17 Feb 2016
Network
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Research output
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Normal Aging Brain Collection Amsterdam (NABCA): A comprehensive collection of postmortem high-field imaging, neuropathological and morphometric datasets of non-neurological controls
Jonkman, L. E., Graaf, Y. G., Bulk, M., Kaaij, E., Pouwels, P. J. W., Barkhof, F., Rozemuller, A. J. M., van der Weerd, L., Geurts, J. J. G. & van de Berg, W. D. J., 1 Jan 2019, In: NeuroImage: Clinical. 22, 101698.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Axonal degeneration as substrate of fractional anisotropy abnormalities in multiple sclerosis cortex
Preziosa, P., Kiljan, S., Steenwijk, M. D., Meani, A., van de Berg, W. D. J., Schenk, G. J., Rocca, M. A., Filippi, M., Geurts, J. J. G. & Jonkman, L. E., 1 Jul 2019, In: Brain. 142, 7, p. 1921-1937Research output: Contribution to journal › Article › Academic › peer-review
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Diffuse Amyloid-β relates to lower structural degree and higher local efficiency in the posterior cingulate cortex: a post-mortem MRI and histology study.
Jonkman, LE., Steenwijk, MD., Galis-de Graaf, Y., Rozemuller, AJM., Geurts, JJG., Barkhof, F. & van de Berg, WDJ., 2020, (Accepted/In press) In: Neurology.Research output: Contribution to journal › Article › Academic › peer-review
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Post-Mortem MRI and Histopathology in Neurologic Disease: A Translational Approach
Jonkman, L. E., Kenkhuis, B., Geurts, J. J. G. & van de Berg, W. D. J., 2 Apr 2019, In: Neuroscience Bulletin. 35, 2, p. 229-243 15 p.Research output: Contribution to journal › Review article › Academic › peer-review
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Cortical axonal loss is associated with both gray matter demyelination and white matter tract pathology in progressive multiple sclerosis: Evidence from a combined MRI-histopathology study
Kiljan, S., Preziosa, P., Jonkman, L. E., van de Berg, W. D. J., Twisk, J., Pouwels, P. J. W., Schenk, G. J., Rocca, M. A., Filippi, M., Geurts, J. J. G. & Steenwijk, M. D., Mar 2021, In: Multiple Sclerosis Journal. 27, 3, p. 380-390 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Activities
- 1 Membership of board
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Normal Aging Brain Collection (Event)
Wilma van de Berg (Chair), LE Jonkman (Member) & JJG Geurts (Member)
1 Jan 2014 → 1 Jan 2019Activity: Membership › Membership of board
Prizes
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A picture is worth a thousand words: telling the tale of the Parkinson brain with correlative postmortem MRI and microscopy.
Jonkman, Laura (Recipient), van de Berg, Wilma (Recipient), Berendse, Henk (Recipient) & van der Werf, Ysbrand (Recipient), 2019
Prize