Research output per year
Research output per year
Personal profile
Research interests
Curriculum Vitae
1991-1992: Research fellow at Harvard University, Boston, U.S.A. Department of Biochemistry, Boston at the laboratory of Prof. Dr. J. Strominger (Supervision Prof. E.A. Macintyre)
1992: Master Medical Biology, VU University, Amsterdam, The Netherlands.
1993-1998: Doctorate: PhD at the Netherlands Cancer Institute, Department of Immunology, Amsterdam, The Netherlands at the laboratory of Prof. Dr. J. Borst.Thesis defense at 01-09-1998 at Utrecht University (Promoter: Prof. R. Bernards).
1998-1999: Post-doctoral research fellow the Netherlands Cancer Institute (Prof. Dr. J. Borst)
1999-2005: Post-doctoral research fellow at the laboratory of Prof. Dr. H. Clevers, Hubrecht Institute, Laboratory of developmental biology and stem cell research, Utrecht, The Netherlands.
2005-2008: Post-doctoral research fellow at the laboratory of Prof. Dr. R. Bernards, Department of carcinogenesis, Netherlands Cancer Institute, Amsterdam, The Netherlands.
May 2008-May 2008 till present: Principle Investigator, Assistant Professor and head of the molecular diagnostic team at the department of Hematology, Head Prof. Dr. S. Zweegman. Vice-Head: Prof. Dr. G.J. Ossenkoppele. VU University Medical Center, The Netherlands.
Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Research output
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Distinct bone marrow immunophenotypic features define the splicing factor 3B subunit 1 (SF3B1)-mutant myelodysplastic syndromes subtype
Duetz, C., Westers, T. M., in ’t Hout, F. E. M., Cremers, E. M. P., Alhan, C., Venniker-Punt, B., Visser-Wisselaar, H. A., Chitu, D. A., de Graaf, A. O., Smit, L., Jansen, J. H. & van de Loosdrecht, A. A., 2021, In: British Journal of Haematology.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
IGFBP7 activates retinoid acid-induced responses in acute myeloid leukemia stem and progenitor cells
van Gils, N., Verhagen, H. J. M. P., Rutten, A., Menezes, R. X., Tsui, M-L., Vermue, E., Dekens, E., Brocco, F., Denkers, F., Kessler, F. L., Ossenkoppele, G. J., Janssen, J. J. W. M. & Smit, L., 22 Dec 2020, In: Blood. 4, 24, p. 6368-6383 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin
Qiao, X., van der Zanden, S. Y., Wander, D. P. A., Borràs, D. M., Song, J. Y., Li, X., van Duikeren, S., van Gils, N., Rutten, A., van Herwaarden, T., van Tellingen, O., Giacomelli, E., Bellin, M., Orlova, V., Tertoolen, L. G. J., Gerhardt, S., Akkermans, J. J., Bakker, J. M., Zuur, C. L., Pang, B. & 7 others, , 30 Jun 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 26, p. 15182-15192 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia
Naik, J., Themeli, M., de Jong-Korlaar, R., Ruiter, R. W. J., Poddighe, P. J., Yuan, H., de Bruijn, J. D., Ossenkoppele, G. J., Zweegman, S., Smit, L., Mutis, T., Martens, A. C. M., van de Donk, N. W. C. J. & Groen, R. W. J., 28 Feb 2019, In: Haematologica. 104, 3, p. e100-e103Research output: Contribution to journal › Letter › Academic › peer-review
Open Access -
Abstract 1114: IGFBP7 reduces acute myeloid leukemia stem cell survival without affecting normal hematopoiesis
Cil, M., Vermue, E., Zweegman, S., Smit, M., Schuurhuis, G. J., Klootwijk, L. L. D. V., Menezes, R. X., Tsui, M-L., Smit, L., Rutten, A., Gils, N. V., Brocco, F., Roemer, M. G., Ossenkoppele, G. J., Verhagen, H. J., Rhenen, A. V., Janssen, J. J., Denkers, F. & Heukelom, S., 17 Aug 2018, In: Cancer Research. 78, 13 Supplement, p. 1114-1114 1 p.Research output: Contribution to journal › Article › Academic › peer-review
Prizes
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Single Cell Epigenomics Scientific Challenge
Smit, Linda (Recipient), 29 May 2020
Prize: Honorary award