Louis Handoko

DR.

20032020

Research output per year

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Research Output

2020

Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction

van de Bovenkamp, A. A., van Rossum, A. C. & Handoko, M. L., 19 Mar 2020, In : The New England journal of medicine. 382, 12, p. 1180 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

A randomised comparison of the effect of haemodynamic monitoring with CardioMEMS in addition to standard care on quality of life and hospitalisations in patients with chronic heart failure: Design and rationale of the MONITOR HF multicentre randomised clinical trial

Brugts, J. J., Veenis, J. F., Radhoe, S. P., Linssen, G. C. M., van Gent, M., Borleffs, C. J. W., van Ramshorst, J., van Pol, P., Tukkie, R., Spee, R. F., Emans, M. E., Kok, W., van Halm, V., Handoko, L., Beeres, S. L. M. A., Post, M. C., Boersma, E., Lenzen, M. J., Manintveld, O. C., Koffijberg, H. & 10 others, van Baal, P., Versteegh, M., Smilde, T. D., van Heerebeek, L., Rienstra, M., Mosterd, A., Delnoy, P. P. H., Asselbergs, F. W., Brunner-la Rocca, H. P. & de Boer, R. A., 1 Jan 2020, In : Netherlands Heart Journal. 28, 1, p. 16-26 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

CardioMEMS: the next revolution in heart failure management?

Handoko, M. L. & van de Bovenkamp, A. A., 1 Jan 2020, In : Netherlands Heart Journal. 28, 1, p. 14-15 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

Diagnostic value of echocardiographic markers for diastolic dysfunction and heart failure with preserved ejection fraction

Dal Canto, E., Remmelzwaal, S., van Ballegooijen, A. J., Handoko, M. L., Heymans, S., van Empel, V., Paulus, W. J., Nijpels, G., Elders, P. & Beulens, J. W., 1 Jan 2020, (Accepted/In press) In : Heart Failure Reviews.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Modifiable lifestyle factors and heart failure: A Mendelian randomization study

van Oort, S., Beulens, J. W. J., van Ballegooijen, A. J., Handoko, M. L. & Larsson, S. C., Sep 2020, In : American Heart Journal. 227, p. 64-73 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Noninvasive Prediction of Elevated Wedge Pressure in Pulmonary Hypertension Patients Without Clear Signs of Left-Sided Heart Disease: External Validation of the OPTICS Risk Score

Jansen, S. M. A., Huis In 't Veld, A. E., Jacobs, W., Grotjohan, H. P., Waskowsky, M., van der Maten, J., van der Weerdt, A., Hoekstra, R., Overbeek, M. J., Mollema, S. A., Tolen, P. H. C. G., Hassan El Bouazzaoui, L. H., Vriend, J. W. J., Roorda, J. M. M., de Nooijer, R., van der Lee, I., Voogel, B. A. J., Peels, K., Macken, T., Aerts, J. M. & 4 others, Vonk Noordegraaf, A., Handoko, M. L., de Man, F. S. & Bogaard, H. J., 4 Aug 2020, In : Journal of the American Heart Association. 9, 15, p. e015992

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Outpatient treatment of worsening heart failure with intravenous and subcutaneous diuretics: a systematic review of the literature

Wierda, E., Dickhoff, C., Handoko, M. L., Oosterom, L., Kok, W. E., de Rover, Y., de Mol, B. A. J. M., van Heerebeek, L. & Schroeder-Tanka, J. M., 1 Jan 2020, (Accepted/In press) In : ESC Heart Failure. 7, 3, 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

The relevance of a multidomain geriatric assessment in older patients with heart failure

Kleipool, E. E. F., Wiersinga, J. H. I., Trappenburg, M. C., van Rossum, A. C., van Dam, C. S., Liem, S. S., Peters, M. J. L., Handoko, M. L. & Muller, M., 1 Jan 2020, (Accepted/In press) In : ESC Heart Failure. 7, 3, 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access
2019

Diagnostic Accuracy of a Smartphone-Operated, Single-Lead Electrocardiography Device for Detection of Rhythm and Conduction Abnormalities in Primary Care

Himmelreich, J. C. L., Karregat, E. P. M., Lucassen, W. A. M., van Weert, H. C. P. M., de Groot, J. R., Handoko, M. L., Nijveldt, R. & Harskamp, R. E., 1 Sep 2019, In : Annals of Family Medicine. 17, 5, p. 403-411

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

P4515 The aging heart failure patient: frailty and cognitive impairment more common than you would expect - baseline data of the heart-brain clinic

Kleipool, E. E. F., Handoko, M. L., Van Rossum, A. C., Hornstra, J. M., Peters, M. J. L., Liem, S. S. & Muller, M., Oct 2019, In : European Heart Journal. 40, Supplement_1, p. 2736-2736

Research output: Contribution to journalMeeting AbstractAcademic

Open Access
2018

Boosting small heat shock proteins lowers cardiomyocyte passive stiffness in experimental heart failure with preserved ejection fraction

Waddingham, M. T., Dal Canto, E., Bos, D. D. S. G., Sequeria, V., Van Heerebeek, L., Kuster, D. W. D., De Man, F. S., Van Der Velden, J., Handoko, M. L., Eringa, E. C. & Paulus, W. J., May 2018, In : European Journal of Heart Failure. 20, p. 24-24

Research output: Contribution to journalMeeting AbstractAcademic

Chronotropic Incompetence in Chronic Heart Failure

Zweerink, A., van der Lingen, A-L. C. J., Handoko, M. L., van Rossum, A. C. & Allaart, C. P., 2018, In : Circulation. Heart failure. 11, 8, p. e004969

Research output: Contribution to journalArticleAcademicpeer-review

Contribution of impaired parasympathetic activity to right ventricular dysfunction and pulmonary vascular remodeling in pulmonary arterial hypertension

Da Silva Gonçalves Bós, D., Van Der Bruggen, C. E. E., Kurakula, K., Sun, X. Q., Casali, K. R., Casali, A. G., Rol, N., Szulcek, R., Dos Remedios, C., Guignabert, C., Tu, L., Dorfmüller, P., Humbert, M., Wijnker, P. J. M., Kuster, D. W. D., Van Der Velden, J., Goumans, M. J., Bogaard, H. J., Vonk-Noordegraaf, A., De Man, F. S. & 1 others, Handoko, M. L., 1 Jan 2018, In : Circulation. 137, 9, p. 910-924 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Frailty in older adults with cardiovascular disease: Cause, effect or both?

Kleipool, E. E. F., Hoogendijk, E. O., Trappenburg, M. C., Handoko, M. L., Huisman, M., Peters, M. J. L. & Muller, M., 1 Jun 2018, In : Aging and Disease. 9, 3, p. 489-497 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Left ventricular hypertrophy on ECG

Harskamp, R., Vroon, P. & Handoko, L., 2018, In : Huisarts en Wetenschap. 61, 3, p. 18-20

Research output: Contribution to journalArticleAcademicpeer-review

2017

Limited Accuracy of the New ASE/EACVI-Algorithm for Heart Failure With Preserved Ejection Fraction (VeeDIA-Study I)

Enait, V., Oosterveer, F. P., Noordegraaf, A. V., van Rossum, A. C., Paulus, W. J. & Handoko, M. L., 14 Nov 2017, In : Circulation. 136

Research output: Contribution to journalMeeting AbstractAcademic

Pulmonary hypertension in heart failure with preserved ejection fraction: A plea for proper phenotyping and further research

Hoeper, M. M., Lam, C. S. P., Vachiery, J. L., Bauersachs, J., Gerges, C., Lang, I. M., Bonderman, D., Olsson, K. M., Gibbs, J. S. R., Dorfmuller, P., Guazzi, M., Galie, N., Manes, A., Handoko, M. L., Vonk-Noordegraaf, A., Lankeit, M., Konstantinides, S., Wachter, R., Opitz, C. & Rosenkranz, S., 7 Oct 2017, In : European Heart Journal. 38, 38, p. 2869-2873 5 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension

da Silva Gonçalves Bos, D., Happé, C., Schalij, I., Pijacka, W., Paton, J. F. R., Guignabert, C., Tu, L., Thuillet, R., Bogaard, H. J., van Rossum, A. C., Vonk-Noordegraaf, A., de Man, F. S. & Handoko, M. L., 2017, In : JACC: Basic to Translational Science. 2, 1, p. 22-35 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

RV pressure overload: from hypertrophy to failure

van der Bruggen, C. E. E., Tedford, R. J., Handoko, M. L., van der Velden, J. & de Man, F. S., 1 Oct 2017, In : Cardiovascular Research. 113, 12, p. 1423-1432

Research output: Contribution to journalArticleAcademicpeer-review

2016

A critical appraisal of transpulmonary and diastolic pressure gradients

Handoko, M. L., De Man, F. S., Oosterveer, F. P. T., Bogaard, H-J., Vonk-Noordegraaf, A. & Westerhof, N., Sep 2016, In : Physiological Reports. 4, 17, e12910.

Research output: Contribution to journalArticleAcademicpeer-review

Bone Morphogenetic Protein Receptor Type 2 Mutation in Pulmonary Arterial Hypertension A View on the Right Ventricle

van der Bruggen, C. E., Happe, C. M., Dorfmueller, P., Trip, P., Spruijt, O. A., Rol, N., Hoevenaars, F. P., Houweling, A. C., Girerd, B., Marcus, J. T., Mercier, O., Humbert, M., Handoko, M. L., van der Velden, J., Noordegraaf, A. V., Bogaard, H. J., Goumans, M-J. & de Man, F. S., 3 May 2016, In : Circulation. 133, 18, p. 1747-1760

Research output: Contribution to journalArticleAcademicpeer-review

Right Ventricular Myocardial Stiffness in Experimental Pulmonary Arterial Hypertension Relative Contribution of Fibrosis and Myofibril Stiffness

Rain, S., Andersen, S., Najafi, A., Schultz, J. G., Bos, D. D. S. G., Handoko, M. L., Bogaard, H-J., Vonk-Noordegraaf, A., Andersen, A., van der Velden, J., Ottenheijm, C. A. C. & de Man, F. S., Jul 2016, In : Circulation. Heart failure. 9, 7, e002636.

Research output: Contribution to journalArticleAcademicpeer-review

2015

beta-blockers in pulmonary arterial hypertension: evolving concepts of right heart failure

de Man, F. S. & Handoko, M. L., 2015, In : European Respiratory Journal. 46, 3, p. 619-621

Research output: Contribution to journalArticleAcademicpeer-review

Risk-stratification in normotensive acute pulmonary embolism

Handoko, M. L. & de Man, F. S., 2015, In : Netherlands Heart Journal. 23, 1, p. 52-54

Research output: Contribution to journalArticleAcademicpeer-review

2014

Contractile Dysfunction of Left Ventricular Cardiomyocytes in Patients With Pulmonary Arterial Hypertension

Manders, E., Bogaard, H. J., Handoko, M. L., van de Veerdonk, M. C., Keogh, A., Westerhof, N., Stienen, G. J. M., dos Remedios, C. G., Humbert, M., Dorfmuller, P., Fadel, E., Guignabert, C., van der Velden, J., Vonk-Noordegraaf, A., de Man, F. S. & Ottenheijm, C. A. C., 2014, In : Journal of the American College of Cardiology. 64, 1, p. 28-37

Research output: Contribution to journalArticleAcademicpeer-review

Pressure-overload-induced right heart failure

Rain, S., Handoko, M. L., Vonk-Noordegraaf, A., Bogaard, H. J., van der Velden, J. & de Man, F. S., 2014, In : Pflügers Archiv European Journal of Physiology. 466, 6, p. 1055-1063

Research output: Contribution to journalArticleAcademicpeer-review

Protein Changes Contributing to Right Ventricular Cardiomyocyte Diastolic Dysfunction in Pulmonary Arterial Hypertension

Rain, S., da Silva Goncalves Bos, D., Handoko, M. L., Westerhof, N., Stienen, G. J. M., Ottenheijm, C. A. C., Goebel, M., Dorfmuller, P., Guignabert, C., Humbert, M., Bogaard, H. J., dos Remedios, C., Saripalli, C., Hidalgo, C. G., Granzier, H. L., Vonk-Noordegraaf, A., van der Velden, J. & de Man, F. S., 2014, In : Journal of American Heart Association. 3, 3, e000716.

Research output: Contribution to journalArticleAcademicpeer-review

2013

Right ventricular diastolic impairment in patients with pulmonary arterial hypertension

Rain, S., Handoko, M. L., Trip, P., Gan, C. T., Westerhof, N., Stienen, G. J. M., Paulus, W. J., Ottenheijm, C. A. C., Marcus, J. T., Dorfmuller, P., Guignabert, C., Humbert, M., Macdonald, P., dos Remedios, C., Postmus, P. E., Saripalli, C., Hidalgo, C. G., Granzier, H. L., Vonk-Noordegraaf, A., van der Velden, J. & 1 others, de Man, F. S., 2013, In : Circulation. 128, 18, p. 2016-2025

Research output: Contribution to journalArticleAcademicpeer-review

Right ventricular oxygen supply parameters are decreased in human and experimental pulmonary hypertension

Ruiter, G., Wong, Y. Y., de Man, F. S., Handoko, M. L., Jaspers, R. T., Postmus, P. E., Westerhof, N., Niessen, H. W. M., van der Laarse, W. J. & Vonk Noordegraaf, A., Feb 2013, In : Journal of Heart and Lung Transplantation. 32, 2, p. 231-240 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Syphilis: a reversible cause of nephrotic syndrome

Handoko, M. L., Duijvestein, M., Scheepstra, C. G. & de Fijter, C. W. H., 2013, In : BMJ Case Reports. 2013

Research output: Contribution to journalArticleAcademicpeer-review

2012

Bisoprolol Delays Progression Towards Right Heart Failure in Experimental Pulmonary Hypertension

de Man, F. S., Handoko, M. L., van Ballegoij, J. J. M., Schalij, I., Bogaards, S. J. P., Postmus, P. E., van der Velden, J., Westerhof, N., Paulus, W. J. & Vonk Noordegraaf, A., 2012, In : Circulation. Heart failure. 5, 1, p. 97-105

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Diaphragm weakness in pulmonary arterial hypertension: role of sarcomeric dysfunction

Manders, E., de Man, F. S., Handoko, M. L., Westerhof, N., van Hees, H. W. H., Stienen, G. J. M., Vonk Noordegraaf, A. & Ottenheijm, C. A. C., 2012, In : American Journal of Physiology. Lung Cellular and Molecular Physiology. 303, 12, p. L1070-L1078

Research output: Contribution to journalArticleAcademicpeer-review

Dysregulated Renin-Angiotensin-Aldosterone System Contributes to Pulmonary Arterial Hypertension

de Man, F. S., Tu, L., Handoko, M. L., Rain, S., Ruiter, G., Francois, C., Schalij, I., Dorfmuller, P., Simonneau, G., Fadel, E., Perros, F., Boonstra, A., Postmus, P. E., van der Velden, J., Vonk Noordegraaf, A., Humbert, M., Eddahibi, S. & Guignabert, C., 2012, In : American Journal of Respiratory and Critical Care Medicine. 186, 8, p. 780-789

Research output: Contribution to journalArticleAcademicpeer-review

2011

Diaphragm Muscle Fiber Weakness in Pulmonary Hypertension

de Man, F. S., van Hees, H. W. H., Handoko, M. L., Niessen, H. W. M., Schalij, I., Humbert, M., Dorfmuller, P., Mercier, O., Bogaard, H. J., Postmus, P. E., Westerhof, N., Stienen, G. J. M., van der Laarse, W. J., Vonk Noordegraaf, A. & Ottenheijm, C. A. C., 2011, In : American Journal of Respiratory and Critical Care Medicine. 183, 10, p. 1411-1418

Research output: Contribution to journalArticleAcademicpeer-review

The rise and fall of endothelin receptor antagonists in congestive heart failure

Handoko, M. L., de Man, F. S. & Vonk Noordegraaf, A., 2011, In : European Respiratory Journal. 37, 3, p. 484-485

Research output: Contribution to journalArticleAcademicpeer-review

2010

COX-2 Inhibition by Use of Rofecoxib or High Dose Aspirin Enhances ADP-Induced Platelet Aggregation in Fresh Blood

Borgdorff, P., Handoko, M. L., Wong, Y. Y. & Tangelder, G. J., 2010, In : The Open Cardiovascular Medicine Journal. 4, p. 198-205

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
72 Downloads (Pure)

Diabetic cardiomyopathy in Zucker diabetic fatty rats: the forgotten right ventricle

van den Brom, C. E., Bosmans, J. W. A. M., Vlasblom, R., Handoko, M. L., Huisman, M. C., Lubberink, J. M., Molthoff, C. F. M., Lammertsma, A. A., Ouwens, M. D., Diamant, M. & Boer, C., 2010, In : Cardiovascular Diabetology. 9, p. 25 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
67 Downloads (Pure)

Novel treatment strategies for right heart failure in pulmonary arterial hypertension : lessons from the left heart

Handoko, M. L., 2010

Research output: ThesisResearch VU University Amsterdam, graduation VU University Amsterdam

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87 Downloads (Pure)
78 Downloads (Pure)