Research output per year
Research output per year
Personal profile
Research interests
My research is focussed on how neuroinflammation contributes to neurodegeneration in neurological diseases with an emphasis on multiple sclerosis. By defining the molecular mechanisms involved, I aim to uncover new therapeutic targets to halt neurodegeneration.
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration
van Olst, L., Rodriguez Mogeda, C., Picon, C., Kiljan, S., James, R. E., Kamermans, A., van der Pol, S. M. A., Knoop, L., Michailidou, I., Drost, E., Franssen, M., Schenk, G. J., Geurts, J. J. G., Amor, S., Mazarakis, N. D., van Horssen, J., de Vries, H. E., Reynolds, R. & Witte, M. E., Jun 2021, In: Acta Neuropathologica. 141, 6, p. 881-899 19 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Calcium Influx through Plasma-Membrane Nanoruptures Drives Axon Degeneration in a Model of Multiple Sclerosis
Witte, M. E., Schumacher, A-M., Mahler, C. F., Bewersdorf, J. P., Lehmitz, J., Scheiter, A., Sánchez, P., Williams, P. R., Griesbeck, O., Naumann, R., Misgeld, T. & Kerschensteiner, M., 20 Feb 2019, In: Neuron. 101, 4, p. 615-624.e5Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Reduced expression of PGC-1 alpha partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex
Witte, M. E., Nijland, P. G., Drexhage, J. A. R., Gerritsen, W., Geerts, D., van Het Hof, B., Reijerkerk, A., de Vries, H. E., van der Valk, P. & van Horssen, J., 2013, In: Acta Neuropathologica. 125, 2, p. 231-243 13 p.Research output: Contribution to journal › Article › Academic › peer-review
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Breaching Brain Barriers: B Cell Migration in Multiple Sclerosis
Rodriguez-Mogeda, C., Rodríguez-Lorenzo, S., Attia, J., van Horssen, J., Witte, M. E. & de Vries, H. E., 7 Jun 2022, In: Biomolecules. 12, 6, 800.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access -
Inhibitory synaptic loss drives network changes in multiple sclerosis: An ex vivo to in silico translational study
Huiskamp, M., Kiljan, S., Kulik, S., Witte, M. E., Jonkman, L. E., GJM Bol, J., Schenk, G. J., Hulst, H. E., Tewarie, P., Schoonheim, M. M. & Geurts, J. J. G., Nov 2022, In: Multiple Sclerosis Journal. 28, 13, p. 2010-2019 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Prizes
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Best presentation award Dutch MS Research Days
Witte, Maarten (Recipient), 15 Nov 2017
Prize: Other distinction
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Multiple sclerosis international federation (MSIF), Young Researchers’ Award for the best presentation of a translational project.
Witte, Maarten (Recipient), 21 Oct 2011
Prize: Other distinction