Mardien Leoniek Oudega

DR., senior researcher, MD, PhD, MSc


Research output per year

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Personal profile

Research interests

Mardien Leoniek Oudega


MD and PhD Psychiatry, MSc Medial Biology and senior researcher

Department of Old Age Psychiatry, GGZinGeest, Amsterdam UMC, VUmc, the Netherlands

Amsterdam Neuroscience

Born 20-09-1976, Zaanstad, the Netherlands. Married, 2 children


Education and training

1999 MSc Medical Biology taken at VU University Amsterdam, the Netherlands

1999- 2004 Clinical Research Associate and Project manager at PharmaScope and Wyeth Ayerest Research

2008 MD degree taken at VU University Amsterdam, the Netherlands

2010-2016 Resident in psychiatry, GGZinGeest, VU University Amsterdam, the Netherlands

2016 PhD degree taken at VU University Amsterdam, the Netherlands. Defending: "Late life depression, brain characteristics and response to ECT"

2019 BROK

2019 Senior researcher

Research Projects

MODECT: Mood Disorders in Elderly treated with ECT supervising Margot Wagenmakers

Amsterdam Ageing Cohort, cooperation with M. Muller

90+ study, cooperation with P.J. Visser, supervising master thesis student

BLOK study; treating sleeping complaints in patients with psychiatric disorders, cooperation with Tanja Su and supervising Emiel Bour

BrainFit; cognitive online training in patients with uni- and bipolar disorders, cooperation with Margot Wagenmakers and Annemieke Dols

Ageing Cohort of ENIGMA cooperation with Porf. L. Eyler, Margot Wagenmakers, Dick Veltman, Moji, Laura Han, Laura Nawijn

GEMRIC: Gender differences and BrainAGE in relation to ECT response, cooperation with Leif Oltedal, Machteld Blanken

National Collaborations

RESPECT: ECT collega’s Parnassia, AMC, Leuven

Boekhoofdstuk: niet-medicamenteuze behandeling van slaapstoornissen in de psychiatrie samen met Ingrid Verbeek, Tanja Su en Geert Peeters.

Bestuurslid Nederlands Geheugen Netwerk (NGN)

Organisatie Kenniscyclus patiëntenavond

International collaborations


Grants: Stichting tot Steun BrainFit 95.000 euro

Invited Lectures

2010: VJC Maastricht, the Netherlands

2014: VJC Maastricht, the Netherlands

2015: WPA Madrid, Spain

2016: VJC Maastricht. the Netherlands

2017: VJC Maastricht, the Netherlands, Kopenhagen EFFECT meeting

2019: VJC Maastricht workshop sleeping disorders

2019: Slaap 2019 Ermelo, personalized medicine and sleep

2020: VJC Maastricht Workshop slaap, symposium slaap, symposium ECT

2020: Chicago: symposium CBT/chronotherapy : BLOK study 


External positions

Psychiatrist, GGZ InGeest, Amsterdam, Netherlands

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

  • 15 Article
  • 2 Review article
  • 1 Research VU University Amsterdam, graduation VU University Amsterdam

Are Apathy and Depressive Symptoms Related to Vascular White Matter Hyperintensities in Severe Late Life Depression?

Oudega, M. L., Siddiqui, A., Wattjes, M. P., Barkhof, F., Kate, M. T., Muller, M., Bouckaert, F., Vandenbulcke, M., De Winter, F. L., Sienaert, P., Stek, M. L., Comijs, H. C., Korten, N. C. M., Emsell, L., Eikelenboom, P., Rhebergen, D., van Exel, E. & Dols, A., 1 Jan 2020, In : Journal of Geriatric Psychiatry and Neurology.

Research output: Contribution to journalArticleAcademicpeer-review

Brain Changes Induced by Electroconvulsive Therapy Are Broadly Distributed

Ousdal, O. T., Argyelan, M., Narr, K. L., Abbott, C., Wade, B., Vandenbulcke, M., Urretavizcaya, M., Tendolkar, I., Takamiya, A., Stek, M. L., Soriano-Mas, C., Redlich, R., Paulson, O. B., Oudega, M. L., Opel, N., Nordanskog, P., Kishimoto, T., Kampe, R., Jorgensen, A., Hanson, L. G. & 15 others, Hamilton, J. P., Espinoza, R., Emsell, L., van Eijndhoven, P., Dols, A., Dannlowski, U., Cardoner, N., Bouckaert, F., Anand, A., Bartsch, H., Kessler, U., Oedegaard, K. J., Dale, A. M., Oltedal, L. & GEMRIC, 25 Jul 2019, In : Biological Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Brain-derived neurotrophic factor as a possible predictor of electroconvulsive therapy outcome

van Zutphen, E. M., Rhebergen, D., van Exel, E., Oudega, M. L., Bouckaert, F., Sienaert, P., Vandenbulcke, M., Stek, M. & Dols, A., 2019, In : Translational Psychiatry. 9, 1

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Exploring resting state connectivity in patients with psychotic depression

Oudega, M. L., van der Werf, Y. D., Dols, A., Wattjes, M. P., Barkhof, F., Bouckaert, F., Vandenbulcke, M., de Winter, F-L., Sienaert, P., Eikelenboom, P., Stek, M. L., van den Heuvel, O. A., Emsell, L., Rhebergen, D. & van Exel, E., 2019, In : PLoS ONE. 14, 1, e0209908.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Metabolic syndrome rates in older patients with severe mental illness after five years of follow-up and the association with mortality

de Louw, E. J., Paans, N. P. G., Sonnenberg, C. M., Konz, H., Meesters, P. D., van Grootheest, D., Oudega, M. L., Rhebergen, D., Kerssens, C., Comijs, H. C., Stek, M. L. & Dols, A., 1 Feb 2019, In : International Journal of Geriatric Psychiatry. 34, 2, p. 333-336 4 p.

Research output: Contribution to journalArticleAcademicpeer-review


  • 2 Membership of network

GEMRIC, Global Eelctroconvulsive therapy MRI Consortium (Event)

Annemieke Dols (Member), Leif Oltedal (Chair), ML Stek (Member), ML Oudega (Member), Christopher Abbott (Member), Pia Nordanskog (Member), Martin Balslev Jorgensen (Member), Katherine L. Narr (Member), Ronny Redlich (Member), Carles Soriano-Mas (Member), Indira Tendolkar (Member), Philip van Eijndhoven (Member)

Activity: MembershipMembership of network

ResPECT, Research in Psychiatry and ECT (Event)

Annemieke Dols (Chair), F. Bouckaert (Member), Pascal Sienaert (Chair), R. Kok (Member), E. Verwijk (Member), H.P. Spaans (Member), ML Oudega (Member), D Rhebergen (Member), ML Stek (Member), ER van Exel (Member), SNTM Schouws (Member)
2009 → …

Activity: MembershipMembership of network