Martine Chamuleau

DR., PhD, (Principal Investigator)

1991 …2019

Research output per year

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Personal profile

Research interests

M.E.D. Chamuleau, MD PhD is an internist-hematologist with specific expertise in aggressive B-cell Non-Hodgkin lymphoma.

Regarding clinical research: she is the principal investigator of 3 clinical interventional HOVON trials for patients with MYC-driven lymphoma such as double hit lymphoma and Burkitt lymphoma (HOVON 127, 130 and 152). She is also the principal investigator of 2 non-interventional HOVON studies (HOVON 900 and 902) and supervising population-based research on lymphoma in collaboration with the IKNL (PhD D. Issa).

Regarding pre-clinical research she focuses on improving immuno-chemotherapy in aggressive B-cell Non-Hodgkin lymphomas by using hexabodies and duobodies (PhD  H. van der Horst) and by MYC modulation (PhD A.V. de Jonge).


Hematology (aggressive B-cel Non-Hodgkin Lymphoma)

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Research Output

Diffuse large B-cell lymphoma with MYC gene rearrangements: Current perspective on treatment of diffuse large B-cell lymphoma with MYC gene rearrangements; case series and review of the literature

de Jonge, A. V., Roosma, T. J. A., Houtenbos, I., Vasmel, W. L. E., van de Hem, K., de Boer, J. P., van Maanen, T., Lindauer-van der Werf, G., Beeker, A., Timmers, G. J., Schaar, C. G., Soesan, M., Poddighe, P. J., de Jong, D. & Chamuleau, M. E. D., Mar 2016, In : European Journal of Cancer. 55, p. 140-146 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Treatment of sporadic Burkitt lymphoma in adults, a retrospective comparison of four treatment regimens

Oosten, L. E. M., Chamuleau, M. E. D., Thielen, F. W., de Wreede, L. C., Siemes, C., Doorduijn, J. K., Smeekes, O. S., Kersten, M. J., Hardi, L., Baars, J. W., Demandt, A. M. P., Stevens, W. B. C., Nijland, M., van Imhoff, G. W., Brouwer, R., Uyl-de Groot, C. A., Kluin, P. M., de Jong, D. & Veelken, H., 1 Feb 2018, In : Annals of Hematology. 97, 2, p. 255-266 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Successful Treatment of MYC rearrangement Positive Large B Cell Lymphoma Patients with R-CHOP21 Plus Lenalidomide: Results of a Multicenter Phase II HOVON Trial

Chamuleau, M. E. D., Nijland, M., Zijlstra, J. M., Mous, R., Lugtenburg, P. J., Dierickx, D., Imhoff, G. V., Vermaat, J., Bakunina, K., Marijt, E. W. A., Visser, O., Mandigers, C., Bilgin, Y., Burggraaff, C., Hoekstra, O., Jong, D. D. & Kersten, M. J., 21 Nov 2018, In : Blood. 132, Suppl 1, p. 786 1 p.

Research output: Contribution to journalMeeting AbstractAcademic

Treatment and relative survival in very elderly patients with DLBCL in The Netherlands: a population-based study, 1989 to 2015

Dinmohamed, A. G., Issa, D. E., van der Poel, M. W. M., Schouten, H. C., Lugtenburg, P. J., Chamuleau, M. E. D., Zweegman, S. & Visser, O., 2017, In : Blood. 1, 21, p. 1839-1841 3 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering

Oostindie, S. C., Van Der Horst, H. J., Lindorfer, M. A., Cook, E. M., Tupitza, J. C., Zent, C. S., Burack, R., VanDerMeid, K. R., Strumane, K., Chamuleau, M. E. D., Mutis, T., De Jong, R. N., Schuurman, J., Breij, E. C. W., Beurskens, F. J., Parren, P. W. H. I. & Taylor, R. P., 31 Aug 2019, In : Haematologica. 104, 9, p. 1841-1852 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access


  • 1 Membership of board

HOVON Data Centre, Rotterdam, Netherlands (External organisation)

Martine Chamuleau (Member)
1 May 20101 Sep 2019

Activity: MembershipMembership of board