Paul Knaapen

DR., (Principal Investigator)

20032020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Identification and Quantification of Cardiovascular Structures From CCTA: An End-to-End, Rapid, Pixel-Wise, Deep-Learning Method

Baskaran, L., Maliakal, G., Al'Aref, S. J., Singh, G., Xu, Z., Michalak, K., Dolan, K., Gianni, U., van Rosendael, A., van den Hoogen, I., Han, D., Stuijfzand, W., Pandey, M., Lee, B. C., Lin, F., Pontone, G., Knaapen, P., Marques, H., Bax, J., Berman, D. & 3 others, Chang, H-J., Shaw, L. J. & Min, J. K., May 2020, In : JACC: Cardiovascular Imaging. 13, 5, p. 1163-1171 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Netrin-1 and the Grade of Atherosclerosis Are Inversely Correlated in Humans

Bruikman, C. S., Vreeken, D., Hoogeveen, R. M., Bom, M. J., Danad, I., Pinto-Sietsma, S. J., van Zonneveld, A. J., Knaapen, P., Hovingh, G. K., Stroes, E. S. G. & van Gils, J. M., 1 Feb 2020, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 40, 2, p. 462-472 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Prophylactic veno-arterial extracorporeal membrane oxygenation in patients undergoing high-risk percutaneous coronary intervention

van den Brink, F. S., Meijers, T. A., Hofma, S. H., van Boven, A. J., Nap, A., Vonk, A., Symersky, P., Sjauw, K. D. & Knaapen, P., Feb 2020, In : Netherlands Heart Journal. 28, 3, p. 139-144 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Revascularization therapy in stable ischaemic heart disease: Perfusion restores, why does outcome not?

Knaapen, P., 2020, In : European heart journal cardiovascular Imaging. 21, 1, p. 47-48 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

2019

1-Year Outcomes of Delayed Versus Immediate Intervention in Patients With Transient ST-Segment Elevation Myocardial Infarction

Janssens, GN., van der Hoeven, NW., Lemkes, JS., Everaars, H., van de Ven, PM., Marques, KMJ., Nap, A., van Leeuwen, M. A. H., Appelman, JEA., Knaapen, P., Verouden, CJW., Allaart, CP., Brinckman, S., Saraber, CE., Plomp, K., Timmer, J. R., Kedhi, E., Hermanides, R. S., Meuwissen, M., Schaap, J. & 4 others, Van Der Weerdt, A. P., van Rossum, AC., Nijveldt, R. & van Royen, N., 25 Nov 2019, In : JACC Cardiovascular Interventions. 12, 22, p. 2272-2282 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

2-Year Clinical Outcomes of an Abluminal Groove–Filled Biodegradable-Polymer Sirolimus-Eluting Stent Compared With a Durable-Polymer Everolimus-Eluting Stent

Xu, B., Saito, Y., Baumbach, A., Kelbæk, H., van Royen, N., Zheng, M., Morel, M-A., Knaapen, P., Slagboom, T., Johnson, T. W., Vlachojannis, G., Arkenbout, K. E., Holmvang, L., Janssens, L., Ochala, A., Brugaletta, S., Naber, C. K., Anderson, R., Rittger, H., Berti, S. & 10 others, Barbato, E., Toth, G. G., Maillard, L., Valina, C., Buszman, P., Thiele, H., Schächinger, V., Lansky, A., Wijns, W. & TARGET AC Investigators, 9 Sep 2019, In : JACC: Cardiovascular Interventions. 12, 17, p. 1679-1687

Research output: Contribution to journalArticleAcademicpeer-review

Accuracy of RESOLVE score derived from coronary computed tomography versus visual angiography to predict side branch occlusion in percutaneous bifurcation intervention

Opolski, M. P., Grodecki, K., Staruch, A. D., Michalowska, A. M., Kepka, C., Wolny, R., Knaapen, P., Schumacher, S. P., Pregowski, J., Kruk, M., Debski, M., Debski, A., Michalowska, I. & Witkowski, A., 1 Jan 2019, In : JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY.

Research output: Contribution to journalArticleAcademicpeer-review

Artificial Intelligence for Aortic Pressure Waveform Analysis During Coronary Angiography: Machine Learning for Patient Safety

Howard, J. P., Cook, C. M., van de Hoef, T. P., Meuwissen, M., de Waard, G. A., van Lavieren, M. A., Echavarria-Pinto, M., Danad, I., Piek, J. J., Götberg, M., Al-Lamee, R. K., Sen, S., Nijjer, S. S., Seligman, H., van Royen, N., Knaapen, P., Escaned, J., Francis, D. P., Petraco, R. & Davies, J. E., 28 Oct 2019, In : JACC: Cardiovascular Interventions. 12, 20, p. 2093-2101

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Comprehensive physiological evaluation of epicardial and microvascular coronary domains using vascular conductance and zero flow pressure

van der Hoeven, N. W., de Waard, G. A., Quirós, A., De Hoyos, A., Broyd, C., Nijjer, S. S., van de Hoef, T. P., Petraco, R., Driessen, R. S., Mejía-Rentería, H., Kikuta, Y., Echavarría Pinto, M., van de Ven, P. M., Meuwissen, M., Knaapen, P., Piek, J. J., Davies, J. E., van Royen, N. & Escaned, J., 8 Feb 2019, In : EuroIntervention. 14, 15, p. e1593-e1600

Research output: Contribution to journalArticleAcademicpeer-review

Computed Tomography to Replace Invasive Coronary Angiography? Close, but not close enough

Knaapen, P., 1 Feb 2019, In : Circulation. Cardiovascular imaging. 12, 2, p. e008710 e008710.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
Open Access

Coronary Microcirculation Downstream Non-Infarct-Related Arteries in the Subacute Phase of Myocardial Infarction: Implications for Physiology-Guided Revascularization

Mejía-Rentería, H., Lee, J. M., van der Hoeven, N. W., Gonzalo, N., Jiménez-Quevedo, P., Nombela-Franco, L., Núñez-Gil, I. J., Salinas, P., del Trigo, M., Cerrato, E., van Royen, N., Knaapen, P., Koo, B-K., Macaya, C., Fernández-Ortiz, A. & Escaned, J., 7 May 2019, In : Journal of the American Heart Association. 8, 9, p. e011534 e011534.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Diastolic-systolic velocity ratio to detect coronary stenoses under physiological resting conditions: A mechanistic study

de Waard, G. A., Broyd, C. J., Cook, C. M., van der Hoeven, N. W., Petraco, R., Nijjer, S. S., van de Hoef, T. P., Echavarria-Pinto, M., Meuwissen, M., Sen, S., Knaapen, P., Escaned, J., Piek, J. J., van Royen, N. & Davies, J. E., 1 Mar 2019, In : Open Heart. 6, 1, e000968.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Guiding Principles for Chronic Total Occlusion Percutaneous Coronary Intervention: A Global Expert Consensus Document

Brilakis, E. S., Mashayekhi, K., Tsuchikane, E., Abi Rafeh, N., Alaswad, K., Araya, M., Avran, A., Azzalini, L., Babunashvili, A. M., Bayani, B., Bhindi, R., Boudou, N., Boukhris, M., Božinović, N. Ž., Bryniarski, L., Bufe, A., Buller, C. E., Burke, M. N., Büttner, H. J., Cardoso, P. & 81 others, Carlino, M., Christiansen, E. H., Colombo, A., Croce, K., Damas de Los Santos, F., de Martini, T., Dens, J., di Mario, C., Dou, K., Egred, M., ElGuindy, A. M., Escaned, J., Furkalo, S., Gagnor, A., Galassi, A. R., Garbo, R., Ge, J., Goel, P. K., Goktekin, O., Grancini, L., Grantham, J. A., Hanratty, C., Harb, S., Harding, S. A., Henriques, J. P. S., Hill, J. M., Jaffer, F. A., Jang, Y., Jussila, R., Kalnins, A., Kalyanasundaram, A., Kandzari, D. E., Kao, H-L., Karmpaliotis, D., Kassem, H. H., Knaapen, P., Kornowski, R., Krestyaninov, O., Kumar, A. V. G., Laanmets, P., Lamelas, P., Lee, S-W., Lefevre, T., Li, Y., Lim, S-T., Lo, S., Lombardi, W., McEntegart, M., Munawar, M., Navarro Lecaro, J. A., Ngo, H. M., Nicholson, W., Olivecrona, G. R. K., Padilla, L., Postu, M., Quadros, A., Quesada, F. H., Prakasa Rao, V. S., Reifart, N., Saghatelyan, M., Santiago, R., Sianos, G., Smith, E., C Spratt, J., Stone, G. W., Strange, J. W., Tammam, K., Ungi, I., Vo, M., Vu, V. H., Walsh, S., Werner, G. S., Wollmuth, J. R., Wu, E. B., Wyman, R. M., Xu, B., Yamane, M., Ybarra, L. F., Yeh, R. W., Zhang, Q. & Rinfret, S., 30 Jul 2019, In : Circulation. 140, 5, p. 420-433 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

IMMEDIATE VERSUS DELAYED REVASCULARIZATION IN PATIENTS WITH TRANSIENT ST-ELEVATION MYOCARDIAL INFARCTION: 1-YEAR FOLLOW-UP OF THE RANDOMIZED CLINICAL TRANSIENT TRIAL

Janssens, G., Lemkes, J., van der Hoeven, N., van de Ven, P., Marques, K., Nap, A., Van Leeuwen, M., Appelman, Y., Knaapen, P., Verouden, C., Allaart, C., Brinckman, S., Saraber, C., Plomp, K., Timmer, J., Kedhi, E., Hermanides, R., Meuwissen, M., Schaap, J., Van Der Weerdt, A. & 3 others, van Rossum, A., Nijveldt, R. & Van Royen, N., Mar 2019, In : Journal of the American College of Cardiology. 73, 9, p. 1218

Research output: Contribution to journalArticleAcademicpeer-review

Interindividual Variations in the Adenosine-Induced Hemodynamics During Fractional Flow Reserve Evaluation: Implications for the Use of Quantitative Flow Ratio in Assessing Intermediate Coronary Stenoses

Mejía-Rentería, H., Lauri, F. M., Lee, J. M., McInerney, A., van der Hoeven, N. W., de Waard, G. A., Fernández-Ortiz, A., Macaya, C., Knaapen, P., van Royen, N., Koo, B-K. & Escaned, J., 20 Aug 2019, In : Journal of the American Heart Association. 8, 16, p. e012906 e012906.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Mechanisms of Myocardial Infarction in Patients With Nonobstructive Coronary Artery Disease: Results From the Optical Coherence Tomography Study

Opolski, M. P., Spiewak, M., Marczak, M., Debski, A., Knaapen, P., Schumacher, S. P., Staruch, A. D., Grodecki, K., Chmielak, Z., Lazarczyk, H., Kukula, K., Tyczynski, P., Pregowski, J., Dabrowski, M., Kadziela, J., Florczak, E., Skrobisz, A. & Witkowski, A., Nov 2019, In : JACC: Cardiovascular Imaging. 12, 11P1, p. 2210-2221

Research output: Contribution to journalArticleAcademicpeer-review

Percutaneous coronary intervention of chronic total occlusions: When and how to treat

Schumacher, S. P., Stuijfzand, W. J., Opolski, M. P., van Rossum, A. C., Nap, A. & Knaapen, P., Jun 2019, In : Cardiovasc. Revascularization Med.. 20, 6, p. 513-522

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Predictive value of targeted proteomics for coronary plaque morphology in patients with suspected coronary artery disease

Bom, M. J., Levin, E., Driessen, R. S., Danad, I., Van Kuijk, C. C., van Rossum, A. C., Narula, J., Min, J. K., Leipsic, J. A., Belo Pereira, J. P., Taylor, C. A., Nieuwdorp, M., Raijmakers, P. G., Koenig, W., Groen, A. K., Stroes, E. S. G. & Knaapen, P., 1 Jan 2019, In : EBioMedicine. 39, p. 109-117 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

The clinical utility of hybrid imaging for the identification of vulnerable plaque and vulnerable patients

Bing, R., Driessen, R. S., Knaapen, P. & Dweck, M. R., 1 Sep 2019, In : JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY. 13, 5, p. 242-247 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
2018
Open Access

Diagnostic Performance of Hybrid Cardiac Imaging Methods for Assessment of Obstructive Coronary Artery Disease Compared With Stand-Alone Coronary Computed Tomography Angiography. A Meta-Analysis

Rizvi, A., Han, D., Danad, I., Ó Hartaigh, B., Lee, J. H., Gransar, H., Stuijfzand, W. J., Roudsari, H. M., Park, M. W., Szymonifka, J., Chang, H. J., Jones, E. C., Knaapen, P., Lin, F. Y., Min, J. K. & Peña, J. M., 1 Apr 2018, In : JACC: Cardiovascular Imaging. 11, 4, p. 589-599 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of Plaque Burden and Morphology on Myocardial Blood Flow and Fractional Flow Reserve

Driessen, R. S., Stuijfzand, W. J., Raijmakers, P. G., Danad, I., Min, J. K., Leipsic, J. A., Ahmadi, A., Narula, J., van de Ven, P. M., Huisman, M. C., Lammertsma, A. A., van Rossum, A. C., van Royen, N. & Knaapen, P., 6 Feb 2018, In : Journal of the American College of Cardiology. 71, 5, p. 499-509 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

FFRCT Versus SPECT to Diagnose Coronary Artery Disease: Toward a Tailored Approach∗

Knaapen, P., 2018, In : JACC: Cardiovascular Imaging. 11, 11, p. 1651-1653

Research output: Contribution to journalEditorialAcademicpeer-review

FRACTIONAL FLOW RESERVE BUT NOT INSTANTANEOUS WAVE-FREE RATIO DETECTS PLAQUE VULNERABILITY

Driessen, R., Stuijfzand, W., Raijmakers, P., Danad, I., Min, J. K., Leipsic, J., Ahmadi, A., van de Ven, P., van Rossum, A., Narula, J. & Knaapen, P., Mar 2018, In : Journal of the American College of Cardiology. 71, 11, p. A1172

Research output: Contribution to journalArticleAcademicpeer-review

Hyperaemic microvascular resistance predicts clinical outcome and microvascular injury after myocardial infarction

de Waard, G. A., Fahrni, G., de Wit, D., Kitabata, H., Williams, R., Patel, N., Teunissen, P. F., van de Ven, P. M., Umman, S., Knaapen, P., Perera, D., Akasaka, T., Sezer, M., Kharbanda, R. K. & van Royen, N., 1 Jan 2018, In : Heart. 104, 2, p. 127-134 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

One-Year Clinical Outcomes of the Hybrid CTO Revascularization Strategy After Hospital Discharge: A Subanalysis of the Multicenter RECHARGE Registry

Maeremans, J., Avran, A., Walsh, S., Knaapen, P., Hanratty, C. G., Faurie, B., Agostoni, P., Bressollette, E., Kayaert, P., Smith, D., Chase, A., Mcentegart, M. B., Smith, W. H. T., Harcombe, A., Irving, J., Ladwiniec, A., Spratt, J. C., Dens, J. & RECHARGE Investigators, Feb 2018, In : The Journal of invasive cardiology. 30, 2, p. 62-70 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Rational and design of the European randomized Optical Coherence Tomography Optimized Bifurcation Event Reduction Trial (OCTOBER)

Holm, N. R., Andreasen, L. N., Walsh, S., Kajander, O. A., Witt, N., Eek, C., Knaapen, P., Koltowski, L., Gutiérrez-Chico, J. L., Burzotta, F., Kockman, J., Ormiston, J., Santos-Pardo, I., Laanmets, P., Mylotte, D., Madsen, M., Hjort, J., Kumsars, I., Råmunddal, T. & Christiansen, E. H. J., 2018, In : American Heart Journal. 205, p. 97-109

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Subadventitial stenting around occluded stents: A bailout technique to recanalize in-stent chronic total occlusions

Azzalini, L., Karatasakis, A., Spratt, J. C., Tajti, P., Riley, R. F., Ybarra, L. F., Schumacher, S. P., Benincasa, S., Bellini, B., Candilio, L., Mitomo, S., Henriksen, P., Hidalgo, F., Timmers, L., Kraaijeveld, A. O., Agostoni, P., Roy, J., Ramsay, D. R., Weaver, J. C., Knaapen, P. & 11 others, Nap, A., Starcevic, B., Ojeda, S., Pan, M., Alaswad, K., Lombardi, W. L., Carlino, M., Brilakis, E. S., Colombo, A., Rinfret, S. & Mashayekhi, K., 1 Sep 2018, In : Catheterization and Cardiovascular Interventions. 92, 3, p. 466-476 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable polymer coronary stent (TARGET All Comers): a multicentre, open-label, randomised non-inferiority trial

TARGET All Comers Investigators, 2018, In : The Lancet. 392, 10153, p. 1117-1126

Research output: Contribution to journalArticleAcademicpeer-review

Timing of revascularization in patients with transient ST-segment elevation myocardial infarction: a randomized clinical trial

Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., van de Ven, P. M., Marques, K. M. J., Nap, A., van Leeuwen, M. A. H., Appelman, Y. E. A., Knaapen, P., Verouden, N. J. W., Allaart, C. P., Brinckman, S. L., Saraber, C. E., Plomp, K. J., Timmer, J. R., Kedhi, E., Hermanides, R. S., Meuwissen, M., Schaap, J., van der Weerdt, A. P. & 3 others, van Rossum, A. C., Nijveldt, R. & van Royen, N., 26 Oct 2018, In : European Heart Journal. 40, 3, p. 283-291 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Towards a contemporary, comprehensive scoring system for determining technical outcomes of hybrid percutaneous chronic total occlusion treatment: The RECHARGE score

Maeremans, J., Spratt, J. C., Knaapen, P., Walsh, S., Agostoni, P., Wilson, W., Avran, A., Faurie, B., Bressollette, E., Kayaert, P., Bagnall, A. J., Smith, D., Mcentegart, M. B., Smith, W. H. T., Kelly, P., Irving, J., Smith, E. J., Strange, J. W. & Dens, J., 1 Feb 2018, In : Catheterization and Cardiovascular Interventions. 91, 2, p. 192-202 11 p.

Research output: Contribution to journalArticleAcademicpeer-review