Paul Knaapen

DR., (Principal Investigator)

20032020

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1-Year Outcomes of Delayed Versus Immediate Intervention in Patients With Transient ST-Segment Elevation Myocardial Infarction

Janssens, GN., van der Hoeven, NW., Lemkes, JS., Everaars, H., van de Ven, PM., Marques, KMJ., Nap, A., van Leeuwen, M. A. H., Appelman, JEA., Knaapen, P., Verouden, CJW., Allaart, CP., Brinckman, S., Saraber, CE., Plomp, K., Timmer, J. R., Kedhi, E., Hermanides, R. S., Meuwissen, M., Schaap, J. & 4 others, Van Der Weerdt, A. P., van Rossum, AC., Nijveldt, R. & van Royen, N., 25 Nov 2019, In : JACC Cardiovascular Interventions. 12, 22, p. 2272-2282 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

2-Year Clinical Outcomes of an Abluminal Groove–Filled Biodegradable-Polymer Sirolimus-Eluting Stent Compared With a Durable-Polymer Everolimus-Eluting Stent

Xu, B., Saito, Y., Baumbach, A., Kelbæk, H., van Royen, N., Zheng, M., Morel, M-A., Knaapen, P., Slagboom, T., Johnson, T. W., Vlachojannis, G., Arkenbout, K. E., Holmvang, L., Janssens, L., Ochala, A., Brugaletta, S., Naber, C. K., Anderson, R., Rittger, H., Berti, S. & 10 others, Barbato, E., Toth, G. G., Maillard, L., Valina, C., Buszman, P., Thiele, H., Schächinger, V., Lansky, A., Wijns, W. & TARGET AC Investigators, 9 Sep 2019, In : JACC: Cardiovascular Interventions. 12, 17, p. 1679-1687

Research output: Contribution to journalArticleAcademicpeer-review

A case of multiple coronary atresias: a rarity even within the family of coronary anomalies

Teunissen, P. F. A., Marcu, C. B., Knaapen, P. & van Royen, N., 2015, In : European Heart Journal. 36, 29, p. 1936-1936

Research output: Contribution to journalArticleAcademicpeer-review

Accuracy of RESOLVE score derived from coronary computed tomography versus visual angiography to predict side branch occlusion in percutaneous bifurcation intervention

Opolski, M. P., Grodecki, K., Staruch, A. D., Michalowska, A. M., Kepka, C., Wolny, R., Knaapen, P., Schumacher, S. P., Pregowski, J., Kruk, M., Debski, M., Debski, A., Michalowska, I. & Witkowski, A., 1 Jan 2019, In : JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY.

Research output: Contribution to journalArticleAcademicpeer-review

Anatomic Versus Physiologic Assessment of Coronary Artery Disease

Gould, K. L., Johnson, N. P., Bateman, T. M., Beanlands, R. S., Bengel, F. M., Bober, R., Camici, P. G., Cerqueira, M. D., Chow, B. J. W., Di Carli, M. F., Dorbala, S., Gewirtz, H., Gropler, R. J., Kaufmann, P. A., Knaapen, P., Knuuti, J., Merhige, M. E., Rentrop, K. P., Ruddy, T. D., Schelbert, H. R. & 8 others, Schindler, T. H., Schwaiger, M., Sdringola, S., Vitarello, J., Williams, K. A., Gordon, D., Dilsizian, V. & Narula, J., 2013, In : Journal of the American College of Cardiology. 62, 18, p. 1639-1653

Research output: Contribution to journalArticleAcademicpeer-review

Antegrade Dissection and Reentry as Part of the Hybrid Chronic Total Occlusion Revascularization Strategy: A Subanalysis of the RECHARGE Registry (Registry of CrossBoss and Hybrid Procedures in France, the Netherlands, Belgium and United Kingdom)

Maeremans, J., Dens, J., Spratt, J. C., Bagnall, A. J., Stuijfzand, W., Nap, A., Agostoni, P., Wilson, W., Hanratty, C. G., Wilson, S., Faurie, B., Avran, A., Bressollette, E., Egred, M., Knaapen, P. & Walsh, S., 1 Jun 2017, In : Circulation: Cardiovascular Interventions. 10, 6, e004791.

Research output: Contribution to journalArticleAcademicpeer-review

Antegrade wire escalation for chronic total occlusions in coronary arteries: simple algorithms as a key to success

Maeremans, J., Knaapen, P., Stuijfzand, W. J., Kayaert, P., Pereira, B., Barbato, E. & Dens, J., Sep 2016, In : JOURNAL OF CARDIOVASCULAR MEDICINE. 17, 9, p. 680-686

Research output: Contribution to journalArticleAcademicpeer-review

A randomized study of the effect of carbonated water prior to myocardial SPECT

Vermeltfoort, I. A. C., van Dijk, A. B., de Jong, J. A. F., Teule, G. J. J., Gevers, M., Verhoeven, B., Raaijmakers, E., Knaapen, P. & Raijmakers, P. G. H. M., 2014, In : Annals of nuclear medicine. 28, 7, p. 669-673

Research output: Contribution to journalArticleAcademicpeer-review

Artificial Intelligence for Aortic Pressure Waveform Analysis During Coronary Angiography: Machine Learning for Patient Safety

Howard, J. P., Cook, C. M., van de Hoef, T. P., Meuwissen, M., de Waard, G. A., van Lavieren, M. A., Echavarria-Pinto, M., Danad, I., Piek, J. J., Götberg, M., Al-Lamee, R. K., Sen, S., Nijjer, S. S., Seligman, H., van Royen, N., Knaapen, P., Escaned, J., Francis, D. P., Petraco, R. & Davies, J. E., 28 Oct 2019, In : JACC: Cardiovascular Interventions. 12, 20, p. 2093-2101

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Automatic generation of absolute myocardial blood flow images using [(15)O]H(2)O and a clinical PET/CT scanner

Harms, H. J., Knaapen, P., de Haan, S., Halbmeijer, R., Lammertsma, A. A. & Lubberink, J. M., 2011, In : European Journal of Nuclear Medicine and Molecular Imaging. 38, 5, p. 930-939

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Cardiac PET-CT: advanced hybrid imaging for the detection of coronary artery disease

Knaapen, P., de Haan, S., Hoekstra, O. S., Halbmeijer, R., Appelman, Y. E. A., Groothuis, J. G. J., Comans, E. F. I., Meijerink, M. R., Lammertsma, A. A., Lubberink, J. M., Gotte, M. J. W. & van Rossum, A. C., 2010, In : Netherlands Heart Journal. 18, 2, p. 90-98

Research output: Contribution to journalArticleAcademicpeer-review

Cardiac positron emission tomography: myocardial perfusion and metabolism in clinical practice

Knaapen, P. & Lubberink, J. M., 2008, In : Clinical Research in Cardiology. 97, 11, p. 791-796

Research output: Contribution to journalArticleAcademicpeer-review

Carriers of the hypertrophic cardiomyopathy MYBPC3 mutation are characterized by reduced myocardial efficiency in the absence of hypertrophy and microvascular dysfunction

Timmer, S. A. J., Germans, T., Brouwer, W. P., Lubberink, J. M., van der Velden, J., Wilde, A. A. M., Christiaans, I., Lammertsma, A. A., Knaapen, P. & van Rossum, A. C., 2011, In : European Journal of Heart Failure. 13, 12, p. 1283-1289

Research output: Contribution to journalArticleAcademicpeer-review

Comparison of clinical non-commercial tools for automated quantification of myocardial blood flow using oxygen-15-labelled water PET/CT

Harms, H. J., Nesterov, S. V., Han, C., Danad, I., Leonora, R., Raijmakers, P. G., Lammertsma, A. A., Knuuti, J. & Knaapen, P., 2014, In : European Heart Journal-Cardiovascular Imaging. 15, 4, p. 431-441

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Comparison of Coronary CT Angiography, SPECT, PET, and Hybrid Imaging for Diagnosis of Ischemic Heart Disease Determined by Fractional Flow Reserve

Danad, I., Raijmakers, P. G., Driessen, R. S., Leipsic, J., Raju, R., Naoum, C., Knuuti, J., Mäki, M., Underwood, R. S., Min, J. K., Elmore, K., Stuijfzand, W. J., van Royen, N., Tulevski, I. I., Somsen, A. G., Huisman, M. C., van Lingen, A. A., Heymans, M. W., van de Ven, P. M., van Kuijk, C. & 3 others, Lammertsma, A. A., van Rossum, A. C. & Knaapen, P., 1 Oct 2017, In : JAMA cardiology. 2, 10, p. 1100-1107 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Comparison of different cardiac risk scores for coronary artery disease in symptomatic women: do female-specific risk factors matter?

Rademaker, A. A. E. M., Danad, I., Groothuis, J. G. J., Heymans, M. W., Marcu, C. B., Knaapen, P. & Appelman, Y. E. A., 2014, In : European Journal of Preventive Cardiology. 21, 11, p. 1443-1450

Research output: Contribution to journalArticleAcademicpeer-review

Comprehensive physiological evaluation of epicardial and microvascular coronary domains using vascular conductance and zero flow pressure

van der Hoeven, N. W., de Waard, G. A., Quirós, A., De Hoyos, A., Broyd, C., Nijjer, S. S., van de Hoef, T. P., Petraco, R., Driessen, R. S., Mejía-Rentería, H., Kikuta, Y., Echavarría Pinto, M., van de Ven, P. M., Meuwissen, M., Knaapen, P., Piek, J. J., Davies, J. E., van Royen, N. & Escaned, J., 8 Feb 2019, In : EuroIntervention. 14, 15, p. e1593-e1600

Research output: Contribution to journalArticleAcademicpeer-review

Computed tomography to detect acute myocardial infarction

Katinakis, P. A., Knaapen, P., de Gast, M. & Girbes, A. R. J., 1 Feb 2012, In : Netherlands Journal of Critical Care. 16, 1, p. 29-30 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Coronary artery disease in patients with atypical chest pain with and without diabetes mellitus assessed with coronary CT angiography

Krul, M. M. G., Bogaard, K., Knol, R. J. J., van Rossum, A. C., Knaapen, P., Cornel, J. H. & van der Zant, F. M., 2014, In : BMJ Open Diabetes Research & Care. 2, e000004.

Research output: Contribution to journalArticleAcademicpeer-review

Coronary Microcirculation Downstream Non-Infarct-Related Arteries in the Subacute Phase of Myocardial Infarction: Implications for Physiology-Guided Revascularization

Mejía-Rentería, H., Lee, J. M., van der Hoeven, N. W., Gonzalo, N., Jiménez-Quevedo, P., Nombela-Franco, L., Núñez-Gil, I. J., Salinas, P., del Trigo, M., Cerrato, E., van Royen, N., Knaapen, P., Koo, B-K., Macaya, C., Fernández-Ortiz, A. & Escaned, J., 7 May 2019, In : Journal of the American Heart Association. 8, 9, p. e011534 e011534.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Coronary microvascular resistance: methods for its quantification in humans

Knaapen, P., Camici, P. G., Marques, K. M. J., Nijveldt, R. J., Bax, J. J., Westerhof, N., Gotte, M. J. W., Jerosch-Herold, M., Schelbert, H. R., Lammertsma, A. A. & van Rossum, A. C., 2009, In : Basic Research in Cardiology. 104, 5, p. 485-498

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Coronary pressure and flow relationships in humans: phasic analysis of normal and pathological vessels and the implications for stenosis assessment: a report from the Iberian-Dutch-English (IDEAL) collaborators

Nijjer, S. S., de Waard, G. A., Sen, S., van de Hoef, T. P., Petraco, R., Echavarria-Pinto, M., van Lavieren, M. A., Meuwissen, M., Danad, I., Knaapen, P., Escaned, J., Piek, J. J., Davies, J. E. & van Royen, N., 7 Jul 2016, In : European Heart Journal. 37, 26, p. 2069-2080

Research output: Contribution to journalArticleAcademicpeer-review

Coronary steal: Revealing the diagnosis with quantitative cardiac PET/CT

Heijne, M., Raijmakers, P. G. H. M., Harms, H. J., Lubberink, J. M., Halbmeijer, R., Appelman, Y. E. A. & Knaapen, P., 2010, In : Journal of Nuclear Cardiology. 17, 6, p. 1118-1121

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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61 Downloads (Pure)

Coronary vasomotor function in infarcted and remote myocardium after primary percutaneous coronary intervention

Teunissen, P. F. A., Timmer, S. A. J., Danad, I., de Waard, G. A., van de Ven, P. M., Raijmakers, P. G., Lammertsma, A. A., van Rossum, A. C., van Royen, N. & Knaapen, P., 2015, In : Heart. 101, 19, p. 1577-1583

Research output: Contribution to journalArticleAcademicpeer-review

Delayed contrast enhancement and perfusable tissue index in hypertrophic cardiomyopathy: Comparison between cardiac MRI and PET

Knaapen, P., Van Dockum, W. G., Bondarenko, O., Kok, W. E. M., Götte, M. J. W., Boellaard, R., Beek, A. M., Visser, C. A., Van Rossum, A. C., Lammertsma, A. A. & Visser, F. C., 1 Dec 2005, In : Journal of Nuclear Medicine. 46, 6, p. 923-929 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Determinants of coronary microvascular dysfunction in symptomatic hypertrophic cardiomyopathy

Knaapen, P., Germans, T., Camici, P. G., Rimoldi, O. E., ten Cate, F. J., ten Berg, J. M., Dijkmans, P. A., Boellaard, R., van Dockum, W. G., Gotte, M. J. W., Twisk, J. W. R., van Rossum, A. C., Lammertsma, A. A. & Visser, F. C., 2008, In : American Journal of Physiology. Heart and Circulatory Physiology. 294, 2, p. H986-H993

Research output: Contribution to journalArticleAcademicpeer-review

Determinants of myocardial energetics and efficiency in symptomatic hypertrophic cardiomyopathy

Timmer, S. A. J., Germans, T., Gotte, M. J. W., Rüssel, I. K., Dijkmans, P. A., Lubberink, J. M., ten Berg, J. M., ten Cate, F. J., Lammertsma, A. A., Knaapen, P. & van Rossum, A. C., 2010, In : European Journal of Nuclear Medicine and Molecular Imaging. 37, 4, p. 779-788

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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71 Downloads (Pure)

Diagnosing coronary artery disease with hybrid PET/CT: It takes two to tango

Danad, I., Raijmakers, P. G. & Knaapen, P., 2013, In : Journal of Nuclear Cardiology. 20, 5, p. 874-890

Research output: Contribution to journalArticleAcademicpeer-review

Diagnostic performance of cardiac imaging methods to diagnose ischaemia-causing coronary artery disease when directly compared with fractional flow reserve as a reference standard: A meta-analysis

Danad, I., Szymonifka, J., Twisk, J. W. R., Norgaard, B. L., Zarins, C. K., Knaapen, P. & Min, J. K., 1 Apr 2017, In : European Heart Journal. 38, 13, p. 991-998 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Diagnostic Performance of Hybrid Cardiac Imaging Methods for Assessment of Obstructive Coronary Artery Disease Compared With Stand-Alone Coronary Computed Tomography Angiography. A Meta-Analysis

Rizvi, A., Han, D., Danad, I., Ó Hartaigh, B., Lee, J. H., Gransar, H., Stuijfzand, W. J., Roudsari, H. M., Park, M. W., Szymonifka, J., Chang, H. J., Jones, E. C., Knaapen, P., Lin, F. Y., Min, J. K. & Peña, J. M., 1 Apr 2018, In : JACC: Cardiovascular Imaging. 11, 4, p. 589-599 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Diastolic-systolic velocity ratio to detect coronary stenoses under physiological resting conditions: A mechanistic study

de Waard, G. A., Broyd, C. J., Cook, C. M., van der Hoeven, N. W., Petraco, R., Nijjer, S. S., van de Hoef, T. P., Echavarria-Pinto, M., Meuwissen, M., Sen, S., Knaapen, P., Escaned, J., Piek, J. J., van Royen, N. & Davies, J. E., 1 Mar 2019, In : Open Heart. 6, 1, e000968.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Does myocardial fibrosis hinder contractile function and perfusion in idiopathic dilated cardiomyopathy? PET and MR imaging study

Knaapen, P., Götte, M. J. W., Paulus, W. J., Zwanenburg, J. J. M., Dijkmans, P. A., Boellaard, R., Marcus, J. T., Twisk, J. W. R., Visser, C. A., Van Rossum, A. C., Lammertsma, A. A. & Visser, F. C., 1 Aug 2006, In : Radiology. 240, 2, p. 380-388 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effect of Plaque Burden and Morphology on Myocardial Blood Flow and Fractional Flow Reserve

Driessen, R. S., Stuijfzand, W. J., Raijmakers, P. G., Danad, I., Min, J. K., Leipsic, J. A., Ahmadi, A., Narula, J., van de Ven, P. M., Huisman, M. C., Lammertsma, A. A., van Rossum, A. C., van Royen, N. & Knaapen, P., 6 Feb 2018, In : Journal of the American College of Cardiology. 71, 5, p. 499-509 11 p.

Research output: Contribution to journalArticleAcademicpeer-review