20002020

Research output per year

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Research Output

  • 124 Article
  • 3 Review article
  • 2 Comment/Letter to the editor
2015

On the Origin of Species: Factors Shaping the Establishment of Infant's Gut Microbiota

van Best, N., Hornef, M. W., Savelkoul, P. H. M. & Penders, J., 2015, In : Birth defects research part c-embryo today-reviews. 105, 4, p. 240-251

Research output: Contribution to journalArticleAcademicpeer-review

Plasmid-Mediated AmpC: Prevalence in Community-Acquired Isolates in Amsterdam, the Netherlands, and Risk Factors for Carriage

Reuland, E. A., Halaby, T., Hays, J. P., de Jongh, D. M. C., Snetselaar, H. D. R., Keulen, M., Elders, P. J. M., Savelkoul, P. H. M., Vandenbroucke-Grauls, C. M. J. E. & Naiemi, N., 2015, In : PLoS ONE. 10, 1, e0113033.

Research output: Contribution to journalArticleAcademicpeer-review

The Effect of Sampling and Storage on the Fecal Microbiota Composition in Healthy and Diseased Subjects

Tedjo, D. I., Jonkers, D. M., Savelkoul, P. H. M., Masclee, A. A., van Best, N., Pierik, M. J. & Penders, J., 2015, In : PLoS ONE. 10, 5, e0126685.

Research output: Contribution to journalArticleAcademicpeer-review

Tropheryma whipplei, a Potential Commensal Detected in Individuals Undergoing Routine Colonoscopy

Grasman, M. E., Pettersson, A. M., Catsburg, A., Koek, A. G., van Bodegraven, A. A. & Savelkoul, P. H. M., 2015, In : Journal of Clinical Microbiology. 53, 12, p. 3919-3921

Research output: Contribution to journalArticleAcademicpeer-review

2014

Detection and Occurrence of Plasmid-Mediated AmpC in Highly Resistant Gram-Negative Rods

Reuland, E. A., Hays, J. P., de Jongh, D. M. C., Abdelrehim, E., Willemsen, I., Kluijtmans, J. A. J. W., Savelkoul, P. H. M., Vandenbroucke-Grauls, C. M. J. E. & Naiemi, N., 2014, In : PLoS ONE. 9, 3, e91396.

Research output: Contribution to journalArticleAcademicpeer-review

Development of a multiplex real-time PCR assay for the rapid diagnosis of neonatal late onset sepsis

van den Brand, M., Peters, R. P. H., Catsburg, A., Rubenjan, A., Broeke, F. J., van den Dungen, F. A. M., van Weissenbruch, M. M., van Furth, A. M., Koressaar, T., Remm, M., Savelkoul, P. H. M. & Bos, M. P., 2014, In : Journal of Microbiological Methods. 106, p. 8-15

Research output: Contribution to journalArticleAcademicpeer-review

Endotracheal aspirate and bronchoalveolar lavage fluid analysis: interchangeable diagnostic modalities in suspected ventilator-associated pneumonia?

Scholte, J. B., van Dessel, H. A., Linssen, C. F., Bergmans, D. C., Savelkoul, P. H. M., Roekaerts, P. M. & van Mook, W. N., 2014, In : Journal of Clinical Microbiology. 52, 10, p. 3597-3604

Research output: Contribution to journalArticleAcademicpeer-review

Extended-spectrum beta-lactamase producing Klebsiella spp. in chicken meat and humans: a comparison of typing methods

Overdevest, I. T. M. A., van Heck, M., van der Zwaluw, K., Huijsdens, X., van Santen, M., Rijnsburger, M. C., Eustace, A., Xu, L., Hawkey, P., Savelkoul, P. H. M., Vandenbroucke-Grauls, C., Willemsen, I., van de Ven, J., Verhulst, C. & Kluijtmans, J. A. J. W., 2014, In : Clinical Microbiology and Infection. 20, 3, p. 251-255

Research output: Contribution to journalArticleAcademicpeer-review

Fecal Microbial Composition of Ulcerative Colitis and Crohn's Disease Patients in Remission and Subsequent Exacerbation

Wills, E. S., Jonkers, D. M., Savelkoul, P. H. M., Masclee, A. A., Pierik, M. J. & Penders, J., 2014, In : PLoS ONE. 9, 3, e90981.

Research output: Contribution to journalArticleAcademicpeer-review

Fecal microbiome analysis as a diagnostic test for diverticulitis

Daniels, L., Budding, A. E., de Korte, N., van Eck, A., Bogaards, J. A., Stockmann, H. B., Consten, E. C., Savelkoul, P. H. M. & Boermeester, M. A., 2014, In : European Journal of Clinical Microbiology and Infectious Diseases. 33, 11, p. 1927-1936

Research output: Contribution to journalArticleAcademicpeer-review

High Rates of Antimicrobial Drug Resistance Gene Acquisition after International Travel, the Netherlands

von Wintersdorff, C. J., Penders, J., Stobberingh, E. E., lashof, A. M., Hoebe, C. J., Savelkoul, P. H. M. & Wolffs, P. F., 2014, In : Emerging Infectious Diseases. 20, 4, p. 649-657

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence of ESBL-producing Enterobacteriaceae in raw vegetables

Reuland, E. A., Naiemi, N., Raadsen, S. A., Savelkoul, P. H. M., Kluijtmans, J. A. J. W. & Vandenbroucke-Grauls, C. M. J. E., 2014, In : European Journal of Clinical Microbiology and Infectious Diseases. 33, 10, p. 1843-1846

Research output: Contribution to journalArticleAcademicpeer-review

Rectal Swabs for Analysis of the Intestinal Microbiota

Budding, A. E., Grasman, M. E., van Eck, A., Bogaards, J. A., Vandenbroucke-Grauls, C. M. J. E., van Bodegraven, A. A. & Savelkoul, P. H. M., 2014, In : PLoS ONE. 9, 7, e101344.

Research output: Contribution to journalArticleAcademicpeer-review

Surveillance cultures in intensive care units: a nationwide survey on current practice providing future perspectives

Scholte, J. B., van Mook, W. N., Linssen, C. F., van Dessel, H. A., Bergmans, D. C., Savelkoul, P. H. M. & Roekaerts, P. M., 2014, In : Journal of Critical Care. 29, 5, p. 885.e7-885.e12

Research output: Contribution to journalArticleAcademicpeer-review

The sink as a correctable source of extended-spectrum beta-lactamase contamination for patients in the intensive care unit

Wolf, I., Bergervoet, P. W. M., Sebens, F. W., van den Oever, H. L. A., Savelkoul, P. H. M. & van der Zwet, W. C., 2014, In : Journal of Hospital Infection. 87, 2, p. 126-130

Research output: Contribution to journalArticleAcademicpeer-review

2013

Allelic Imbalance at the HER2/TOP2A Locus in Breast Cancer

Huijsmans, C. J. J., Rigter, H., van den Brule, A. J., Poodt, J., van der Linden, J. C., Savelkoul, P. H. M., Hilbink-Smolders, M. & Hermans, M. H. A., May 2013, In : Annals of Oncology. 24, p. iii29

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Comparison of Pathogen DNA Isolation Methods from Large Volumes of Whole Blood to Improve Molecular Diagnosis of Bloodstream Infections

Loonen, A. J. M., Bos, M. P., van Meerbergen, B., Neerken, S., Catsburg, A., Dobbelaer, I., Penterman, R., Maertens, G., van de Wiel, P., Savelkoul, P. H. M. & van den Brule, A. J. C., 2013, In : PLoS ONE. 8, 8, e72349.

Research output: Contribution to journalArticleAcademicpeer-review

Composition and diversity of the duodenal mucosa-associated microbiome in children with untreated coeliac disease

de Meij, T. G. J., Budding, A. E., Grasman, M. E., Kneepkens, C. M. F., Savelkoul, P. H. M. & Mearin, M. L., 2013, In : Scandinavian Journal of Gastroenterology. 48, 5, p. 530-536

Research output: Contribution to journalArticleAcademicpeer-review

Evaluation of a new real-time PCR assay (Check-Direct CPE) for rapid detection of KPC,OXA-48,VIM,and NDM carbapenemases using spiked rectal swabs

Nijhuis, R., Samuelsen, O., Savelkoul, P. H. M. & van Zwet, A. A., 2013, In : Diagnostic microbiology and infectious disease. 77, 4, p. 316-320

Research output: Contribution to journalArticleAcademicpeer-review

Extended-Spectrum beta-Lactamase-Producing Escherichia coli From Retail Chicken Meat and Humans: Comparison of Strains, Plasmids, Resistance Genes, and Virulence Factors

Kluijtmans, J. A. J. W., Overdevest, I. T. M. A., Willemsen, I., Kluytmans-van den Bergh, M., van der Zwaluw, K., van Heck, M., Rijnsburger, M., Vandenbroucke-Grauls, C. M. J. E., Savelkoul, P. H. M., Johnston, B. D., Gordon, D. & Johnson, J. R., 2013, In : Clinical Infectious Diseases. 56, 4, p. 478-487

Research output: Contribution to journalArticleAcademicpeer-review

High prevalence of ESBL-producing Enterobacteriaceae carriage in Dutch community patients with gastrointestinal complaints

Reuland, E. A., Overdevest, I. T. M. A., Naiemi, N., Kalpoe, J. S., Rijnsburger, M. C., Raadsen, S. A., Ligtenberg-Burgman, I., van der Zwaluw, K. W., van Heck, M., Savelkoul, P. H. M., Kluijtmans, J. A. J. W. & Vandenbroucke-Grauls, C. M. J. E., 2013, In : Clinical Microbiology and Infection. 19, 6, p. 542-549

Research output: Contribution to journalArticleAcademicpeer-review

High Resolution Typing by Whole Genome Mapping Enables Discrimination of LA-MRSA (CC398) Strains and Identification of Transmission Events

Bosch, T., Verkade, E., van Luit, M., Pot, B., Vauterin, P., Burggrave, R., Savelkoul, P. H. M., Kluijtmans, J. A. J. W. & Schouls, L., 2013, In : PLoS ONE. 8, 6, e66493.

Research output: Contribution to journalArticleAcademicpeer-review

Performance of cobas(R) 4800 and m2000 real-time assays for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in rectal and self-collected vaginal specimen

Geelen, T. H., Rossen, J. W., Beerens, A. M., Poort, L., Morré, S. A., Ritmeester, W. S., van Kruchten, H. E., van de Pas, M. M. & Savelkoul, P. H. M., 2013, In : Diagnostic microbiology and infectious disease. 77, 2, p. 101-105

Research output: Contribution to journalArticleAcademicpeer-review

Rapid plasmid replicon typing by real time PCR melting curve analysis

Boot, M., Raadsen, S., Savelkoul, P. H. M. & Vandenbroucke-Grauls, C., 2013, In : BMC Microbiology. 13, 83.

Research output: Contribution to journalArticleAcademicpeer-review

The human microbiome as a reservoir of antimicrobial resistance

Penders, J., Stobberingh, E. E., Savelkoul, P. H. M. & Wolffs, P. F., 2013, In : Frontiers in Microbiology. 4, 87.

Research output: Contribution to journalArticleAcademicpeer-review

2012

A Case of New Delhi Metallo-beta-Lactamase 1 (NDM-1)-Producing Klebsiella pneumoniae with Putative Secondary Transmission from the Balkan Region in the Netherlands

Halaby, T., Reuland, A. E., Naiemi, N., Potron, A., Savelkoul, P. H. M., Vandenbroucke-Grauls, C. M. J. E. & Nordmann, P., 2012, In : Antimicrobial Agents and Chemotherapy. 56, 5, p. 2790-2791

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
14 Downloads (Pure)

Characterization of imipenem resistance mechanisms in Pseudomonas aeruginosa isolates from Turkey

Mac Aogain, M., Kulah, C., Rijnsburger, M., Celebi, G., Savelkoul, P. H. M., O'Gara, F. & Mooij, M. J., 2012, In : Clinical Microbiology and Infection. 18, 7, p. E262-E265

Research output: Contribution to journalArticleAcademicpeer-review

Microbiële typering, een kwestie van onderscheid maken

Savelkoul, P. H. M., van Doorn, J., Duim, B., Figge, M., van Heck, M., Melles, D., Molenkamp, R., Schouls, L. & Top, J., 2012, In : Nederlands tijdschrift voor medische microbiologie. 20, 1, p. 16-20

Research output: Contribution to journalArticleProfessional

No human transmission of Mycobacterium malmoense in a perfect storm setting

Hoefsloot, W., Boeree, M. J., van Nieuwkoop, C., Bernards, A. T., Savelkoul, P. H. M., van Ingen, J. & van Soolingen, D., 2012, In : European Respiratory Journal. 40, 6, p. 1576-1578

Research output: Contribution to journalArticleAcademicpeer-review

Rapid detection of methicillin-resistant Staphylococcus aureus in screening samples by relative quantification between the mecA gene and the SA442 gene

Bode, L. G. M., van Wunnik, P., Vaessen, N., Savelkoul, P. H. M. & Smeets, L., 2012, In : Journal of Microbiological Methods. 89, 2, p. 129-132

Research output: Contribution to journalArticleAcademicpeer-review

Rapid molecular detection of extended-spectrum beta-lactamase gene variants with a novel ligation-mediated real-time PCR

Nijhuis, R., van Zwet, A., Stuart, J. C., Weijers, T. & Savelkoul, P. H. M., 2012, In : Journal of Medical Microbiology. 61, 11, p. 1563-1567

Research output: Contribution to journalArticleAcademicpeer-review

Recent Emergence of Staphylococcus aureus Clonal Complex 398 in Human Blood Cultures

Verkade, E., Bergmans, A. M. C., Budding, A. E., van Belkum, A., Savelkoul, P. H. M., Buiting, A. G. & Kluijtmans, J. A. J. W., 2012, In : PLoS ONE. 7, 10, e41855.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
57 Downloads (Pure)

Single Nucleotide Polymorphism (SNP)-Based Loss of Heterozygosity (LOH) Testing by Real Time PCR in Patients Suspect of Myeloproliferative Disease

Huijsmans, C. J. J., Poodt, J., Damen, J., van der Linden, J. C., Savelkoul, P. H. M., Pruijt, J. F. M., Hilbink, M. & Hermans, M. H. A., 2012, In : PLoS ONE. 7, 7, e38362.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
56 Downloads (Pure)
2011

Abiotrophia defectiva infection of a total hip arthroplasty diagnosed by 16S rRNA gene sequencing

Rozemeijer, W., Jiya, T. U., Rijnsburger, E. R., Heddema, E. R., Savelkoul, P. H. M. & Ang, C. W., 2011, In : Diagnostic microbiology and infectious disease. 70, 1, p. 142-144

Research output: Contribution to journalArticleAcademicpeer-review

Coxiella burnetii DNA in goat milk after vaccination with Coxevac (R)

Hermans, M. H. A., Huijsmans, C. J. J., Schellekens, J. J. A., Savelkoul, P. H. M. & Wever, P. C., 2011, In : Vaccine. 29, 15, p. 2653-2656

Research output: Contribution to journalArticleAcademicpeer-review

Distribution, origin and contamination risk of coagulase-negative staphylococci from platelet concentrates

Rood, I. G. H., de Korte, D., Ramirez-Arcos, S., Savelkoul, P. H. M. & Pettersson, A., 2011, In : Journal of Medical Microbiology. 60, 5, p. 592-599

Research output: Contribution to journalArticleAcademicpeer-review

Distribution of extended-spectrum beta-lactamase genes using a commercial DNA micro-array system

Nijhuis, R. H. T., van Zwet, A. A., Savelkoul, P. H. M., Roovers, E. A., Bosboom, R. W., Postma, B. & van Griethuysen, A. J., 2011, In : Journal of Hospital Infection. 79, 4, p. 349-353

Research output: Contribution to journalArticleAcademicpeer-review

Evaluation of the DiversiLab Typing Method in a Multicenter Study Assessing Horizontal Spread of Highly Resistant Gram-Negative Rods

Overdevest, I. T. M. A., Willemsen, I., Elberts, S., Verhulst, C., Rijnsburger, M., Savelkoul, P. H. M. & Kluijtmans, J. A. J. W., 2011, In : Journal of Clinical Microbiology. 49, 10, p. 3551-3554

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
52 Downloads (Pure)

Extended-Spectrum beta-Lactamase Genes of Escherichia coli in Chicken Meat and Humans, the Netherlands

Overdevest, I., Willemsen, I., Rijnsburger, M. C., Eustace, A., Xu, L., Hawkey, P., van Heck, M., Savelkoul, P. H. M., Vandenbroucke-Grauls, C. M. J. E., van der Zwaluw, K., Huijsdens, X. & Kluijtmans, J. A. J. W., 2011, In : Emerging Infectious Diseases. 17, 7, p. 1216-1222

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
46 Downloads (Pure)

Genetic markers for Clostridium difficile lineages linked to hypervirulence

Knetsch, C. W., Hensgens, M. P. M., Harmanus, C., van der Bijl, M. W., Savelkoul, P. H. M., Kuijper, E. J., Corver, J. & van Leeuwen, H. C., 2011, In : Microbiology. 157, p. 3113-3123

Research output: Contribution to journalArticleAcademicpeer-review

Highly Resistant Gram-Negative Microorganisms: Incidence Density and Occurrence of Nosocomial Transmission (TRIANGLe Study)

Willemsen, I., Elberts, S., Verhulst, C., Rijnsburger, M., Filius, M., Savelkoul, P. H. M., Kluijtmans, J. A. J. W., Lommerse, E., Spanjaard, L., Vlaminckx, B., Vos, A., Wulf, M., Vos, M., Wintermans, R., Andriesse, G., van Zeijl, J., van der Vorm, E., Buiting, A., Sturm, P., Blok, H. & 3 others, Troelstra, A., Kaiser, A. & Vandenbroucke-Grauls, C., 2011, In : Infection Control and Hospital Epidemiology. 32, 4, p. 333-341

Research output: Contribution to journalArticleAcademicpeer-review

Molecular relatedness of Propionibacterium species isolated from blood products and on the skin of blood donors

Rood, I. G. H., de Korte, D., Savelkoul, P. H. M. & Pettersson, A., 2011, In : Transfusion. 51, 10, p. 2118-2125

Research output: Contribution to journalArticleAcademicpeer-review

New Diagnostic Microarray (Check-KPC ESBL) for Detection and Identification of Extended-Spectrum Beta-Lactamases in Highly Resistant Enterobacteriaceae

Willemsen, I., Overdevest, I., Naiemi, N., Rijnsburger, M., Savelkoul, P. H. M., Vandenbroucke-Grauls, C. & Kluijtmans, J. A. J. W., 2011, In : Journal of Clinical Microbiology. 49, 8, p. 2985-2987

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
56 Downloads (Pure)

Performance and suitability of polymerase chain reaction for early detection of bacteria in platelet concentrates

Rood, I. G. H., Pettersson, A., Savelkoul, P. H. M. & de Korte, D., 2011, In : Transfusion. 51, 9, p. 2006-2011

Research output: Contribution to journalArticleAcademicpeer-review

Sensitive Detection and Quantification of the JAK2V617F Allele by Real-Time PCR Blocking Wild-Type Amplification by Using a Peptide Nucleic Acid Oligonucleotide

Huijsmans, C. J., Poodt, J., Savelkoul, P. H. M. & Hermans, M. H., 2011, In : The Journal of molecular diagnostics. 13, 5, p. 558-564

Research output: Contribution to journalArticleAcademicpeer-review

Single-Nucleotide-Polymorphism Genotyping of Coxiella burnetii during a Q Fever Outbreak in The Netherlands

Huijsmans, C. J. J., Schellekens, J. J. A., Wever, P. C., Toman, R., Savelkoul, P. H. M., Janse, I. & Hermans, M. H. A., 2011, In : Applied and Environmental Microbiology. 77, 6, p. 2051-2057

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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56 Downloads (Pure)
2010

Alarmingly poor performance in Chlamydia trachomatis point-of-care testing

van Dommelen, L., van Tiel, F. H., Ouburg, S., Brouwers, E. E. H. G., Terporten, P. H. W., Savelkoul, P. H. M., Morre, S. A., Bruggeman, C. A. & Hoebe, C. J. P. A., 2010, In : Sexually Transmitted Infections. 86, 5, p. 355-359

Research output: Contribution to journalArticleAcademicpeer-review

Binary IS Typing for Staphylococcus aureus

Budding, A. E., Vandenbroucke-Grauls, C. M. J. E., Melles, D. C., van Duijkeren, E., Kluijtmans, J. A. J. W. & Savelkoul, P. H. M., 2010, In : PLoS ONE. 5, 10, p. e13671 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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62 Downloads (Pure)

Characterisation of carbapenem-resistant Acinetobacter baumannii outbreak strains producing OXA-58 in Turkey

Kulah, C., Mooij, M. J., Comert, F., Aktas, E., Celebi, G., Ozlu, N., Rijnsburger, M. C. & Savelkoul, P. H. M., 2010, In : International Journal of Antimicrobial Agents. 36, 2, p. 114-118

Research output: Contribution to journalArticleAcademicpeer-review

Comparative analysis of four methods to extract DNA from paraffin-embedded tissues: effect on downstream molecular applications.

Huijsmans, C. J. J., Damen, J., van der Linden, J. C., Savelkoul, P. H. M. & Hermans, M. H. A., 2010, In : BMC Research Notes. 3, p. 239 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
56 Downloads (Pure)