Paul van Leeuwen

PROF.DR.

19972019

Research output per year

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Research Output

2019
2018

Effects of a Carbohydrate-, Glutamine-, and Antioxidant-Enriched Oral Nutrition Supplement on Major Surgery-Induced Insulin Resistance: A Randomized Pilot Study

van Stijn, M. F. M., Soeters, M. R., van Leeuwen, P. A. M., Schreurs, W. H., Schoorl, M. G., Twisk, J. W. R., De Bandt, J-P., Bonnefont-Rousselot, D., Cynober, L., Ackermans, M. T., Serlie, M. J. & Houdijk, A. P. J., 1 May 2018, In : Journal of Parenteral and Enteral Nutition. 42, 4, p. 719-729 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1

Buijs, N., Oosterink, J. E., Jessup, M., Schierbeek, H., Stolz, D. B., Houdijk, A. P., Geller, D. A. & van Leeuwen, P. A., 1 Nov 2017, In : Angiogenesis. 20, 4, p. 557-565 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Local adjuvant treatment with low-dose CpG-B offers durable protection against disease recurrence in clinical stage I–II melanoma: Data from two randomized phase II trials

Koster, B. D., Van Den Hout, M. F. C. M., Sluijter, B. J. R., Molenkamp, B. G., Vuylsteke, R. J. C. L. M., Baars, A., Van Leeuwen, P. A. M., Scheper, R. J., Petrousjka van den Tol, M., Van Den Eertwegh, A. J. M. & De Gruijl, T. D., 1 Oct 2017, In : Clinical Cancer Research. 23, 19, p. 5679-5686 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Melanoma sequentially suppresses different DC subsets in the sentinel lymph node, affecting disease spread and recurrence

Van Den Hout, M. F. C. M., Koster, B. D., Sluijter, B. J. R., Molenkamp, B. G., Van De Ven, R., Van Den Eertwegh, A. J. M., Scheper, R. J., Van Leeuwen, P. A. M., Van Den Tol, M. P. & De Gruijl, T. D., 1 Nov 2017, In : Cancer Immunology Research. 5, 11, p. 969-977 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The Mechanisms and Effects of Physical Activity on Breast Cancer

de Boer, M. C., Wörner, E. A., Verlaan, D. & van Leeuwen, P. A. M., 1 Jul 2017, In : Clinical Breast Cancer. 17, 4, p. 272-278 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

2016

Enteral Glutamine Administration in Critically Ill Nonseptic Patients Does Not Trigger Arginine Synthesis

Vermeulen, M. A. R., Brinkmann, S. J. H., Buijs, N., Beishuizen, A., Bet, P. M., Houdijk, A. P. J., van Goudoever, J. B. & van Leeuwen, P. A. M., 2016, In : Journal of nutrition and metabolism. 13 p., 1373060.

Research output: Contribution to journalArticleAcademicpeer-review

Local delivery of CpG-B and GM-CSF induces concerted activation of effector and regulatory T cells in the human melanoma sentinel lymph node

van den Hout, M. F. C. M., Sluijter, B. J. R., Santegoets, S. J. A. M., van Leeuwen, P. A. M., van den Tol, M. P., van den Eertwegh, A. J. M., Scheper, R. J. & de Gruijl, T. D., Apr 2016, In : Cancer Immunology and Immunotherapy. 65, 4, p. 405-415

Research output: Contribution to journalArticleAcademicpeer-review

Perioperative glutamine supplementation restores disturbed renal arginine synthesis after open aortic surgery: a randomized controlled clinical trial

Brinkmann, S. J. H., Buijs, N., Vermeulen, M. A. R., Oosterink, E., Schierbeek, H., Beishuizen, A., de Vries, J-P. P. M., Wisselink, W. & van Leeuwen, P. A. M., 1 Sep 2016, In : American Journal of Physiology. Renal Physiology. 311, 3, p. F567-F575

Research output: Contribution to journalArticleAcademicpeer-review

Strict glucose control and artificial regulation of the NO-ADMA-DDAH system in order to prevent endothelial dysfunction

Brinkmann, S. J. H., Worner, E. A. & van Leeuwen, P. A. M., 1 Jun 2016, In : Journal of Physiology - London. 594, 11, p. 2775-2776

Research output: Contribution to journalArticleAcademicpeer-review

Taurine Concentrations Decrease in Critically Ill Patients with Shock Given Enteral Nutrition

Vermeulen, M. A. R., Van Stijn, M. F. M., Visser, M., Lemmens, S. M. P., Houdijk, A. P. J., Van Leeuwen, P. A. M. & Oudemans-Van Straaten, H. M., 1 Feb 2016, In : Journal of Parenteral and Enteral Nutrition. 40, 2, p. 264-272 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2015

Adaptations of Arginine's Intestinal-Renal Axis in Cachectic Tumor-Bearing Rats

Buijs, N., Vermeulen, M. A. R., Weeda, V. B., Bading, J. R., Houdijk, A. P. J. & van Leeuwen, P. A. M., 2015, In : Nutrition and Cancer. 67, 5, p. 713-720

Research output: Contribution to journalArticleAcademicpeer-review

Comparison of two devices for the treatment of keloid scars with the use of intralesional cryotherapy: An experimental study

van Leeuwen, M. C. E., Bulstra, A. E. J., van der Veen, A. J., Bloem, W. B., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Cryobiology. 71, 1, p. 146-150

Research output: Contribution to journalArticleAcademicpeer-review

Effect of Oral Taurine on Morbidity and Mortality in Elderly Hip Fracture Patients: A Randomized Trial

van Stijn, M. F. M., Bruins, A. A., Vermeulen, M. A. R., Witlox, J., Teerlink, T., Schoorl, M. G., De Bandt, J. P., Twisk, J. W. R., van Leeuwen, P. A. M. & Houdijk, A. P. J., 2015, In : International Journal of Molecular Sciences. 16, 6, p. 12288-12306

Research output: Contribution to journalArticleAcademicpeer-review

Glutamine supplementation, citrulline production, and de novo arginine synthesis: is there a relation? Reply

Buijs, N., Brinkmann, S. J. H., Oosterink, J. E., Luttikhold, J., Schierbeek, H., Wisselink, W., Beishuizen, A., van Goudoever, J. B., Houdijk, A. P. J., van Leeuwen, P. A. M. & Vermeulen, M. A. R., 2015, In : American Journal of Clinical Nutrition. 101, 4, p. 892-893

Research output: Contribution to journalArticleAcademicpeer-review

Intralesional Cryotherapy for the Treatment of Keloid Scars: Evaluating Effectiveness

van Leeuwen, M. C. E., Bulstra, A. E., Ket, J. C. F., Ritt, M. J. P. F., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Plastic and reconstructive surgery.Global open. 3, 6, p. e437-e437

Research output: Contribution to journalArticleAcademicpeer-review

Intralesional Cryotherapy for Treatment of Keloid Scars: A Prospective Study

van Leeuwen, M. C. E., van der Wal, M. B. A., Bulstra, A. E. J., Galindo Garre, F., Molier, J., van Zuijlen, P. P. M., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Plastic and reconstructive surgery. 135, 2, p. 580-589

Research output: Contribution to journalArticleAcademicpeer-review

Jejunal Casein Feeding Is Followed by More Rapid Protein Digestion and Amino Acid Absorption When Compared with Gastric Feeding in Healthy Young Men

Luttikhold, J., van Norren, K., Buijs, N., Ankersmit, M., Heijboer, A. C., Gootjes, J., Rijna, H., van Leeuwen, P. A. M. & van Loon, L. J. C., 2015, In : The Journal of nutrition. 145, 9, p. 2033-2038

Research output: Contribution to journalArticleAcademicpeer-review

Nutrition before and during Surgery and the Inflammatory Response of the Heart: A Randomized Controlled Trial

Visser, M., Niessen, H. W., Kok, W. E. M., Cocchieri, R., Wisselink, W., van Leeuwen, P. A. M. & De Mol, B. A. J. M., 2015, In : Journal of nutrition and metabolism. 2015, 123158.

Research output: Contribution to journalArticleAcademicpeer-review

Reply: Intralesional cryotherapy for the treatment of keloid scars: A prospective study

Van Leeuwen, M. C. E., Van Der Wal, M. B. A., Bulstra, A. E. J., Galindo-Garre, F., Molier, J., Van Zuijlen, P. P. M., Van Leeuwen, P. A. M. & Niessen, F. B., 1 Jan 2015, In : Plastic and reconstructive surgery. 136, 3, p. 399e-400e

Research output: Contribution to journalLetterAcademicpeer-review

Reply: High-Dose-Rate Brachytherapy for the Treatment of Recalcitrant Keloids: A Unique Effective Treatment Protocol

van Leeuwen, M. C. E., Stokmans, S. C., Bulstra, A. E. J., Meijer, O. W. M., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Plastic and reconstructive surgery. 135, 4, p. 792E-793E

Research output: Contribution to journalArticleAcademicpeer-review

Reply: Intralesional Cryotherapy for the Treatment of Keloid Scars: A Prospective Study

van Leeuwen, M. C. E., van der Wal, M. B. A., Bulstra, A. E. J., Galindo Garre, F., Molier, J., van Zuijlen, P. P. M., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Plastic and reconstructive surgery. 136, 3, p. 395E-397E

Research output: Contribution to journalArticleAcademicpeer-review

Surgical Excision with Adjuvant Irradiation for Treatment of Keloid Scars: A Systematic Review

van Leeuwen, M. C. E., Stokmans, S. C., Bulstra, A. E., Meijer, O. W. M., Heymans, M. W., Ket, J. C. F., Ritt, M. J. P. F., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Plastic and reconstructive surgery.Global open. 3, 7, e440.

Research output: Contribution to journalArticleAcademicpeer-review

2014

A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy

van Leeuwen, M. C. E., Bulstra, A. E. J., van Leeuwen, P. A. M. & Niessen, F. B., 2014, In : Journal of Plastic, Reconstructive and Aesthetic Surgery. 67, 12, p. 1703-1710

Research output: Contribution to journalArticleAcademicpeer-review

Assessment of Lesion Response in the Initial Radioiodine Treatment of Differentiated Thyroid Cancer Using I-124 PET Imaging

Jentzen, W., Hoppenbrouwers, J., van Leeuwen, P. A. M., van der Velden, D., van de Kolk, R., Poeppel, T. D., Nagarajah, J., Brandau, W., Bockisch, A. & Rosenbaum-Krumme, S., 2014, In : Journal of Nuclear Medicine. 55, 11, p. 1759-1765

Research output: Contribution to journalArticleAcademicpeer-review

Asymmetric dimethylarginine and critical illness

Brinkmann, S. J. H., de Boer, M. C., Buijs, N. & van Leeuwen, P. A. M., 2014, In : Current Opinion in Clinical Nutrition and Metabolic Care. 17, 1, p. 90-97

Research output: Contribution to journalArticleAcademicpeer-review

High-Dose-Rate Brachytherapy for the Treatment of Recalcitrant Keloids: A Unique, Effective Treatment Protocol

van Leeuwen, M. C. E., Stokmans, S. C., Bulstra, A. E. J., Meijer, O. W. M., van Leeuwen, P. A. M. & Niessen, F. B., 2014, In : Plastic and reconstructive surgery. 134, 3, p. 527-534

Research output: Contribution to journalArticleAcademicpeer-review

Intravenous glutamine supplementation enhances renal de nova arginine synthesis in humans: a stable isotope study

Buijs, N., Brinkmann, S. J. H., Oosterink, J. E., Luttikhold, J., Schierbeek, H., Wisselink, W., Beishuizen, A., van Goudoever, J. B., Houdijk, A. P. J., van Leeuwen, P. A. M. & Vermeulen, M. A. R., 2014, In : American Journal of Clinical Nutrition. 100, 5, p. 1385-1391

Research output: Contribution to journalArticleAcademicpeer-review

Nutrition before, during, and after surgery increases the arginine:asymmetric dimethylarginine ratio and relates to improved myocardial glucose metabolism: a randomized controlled trial

Visser, M., Davids, M., Verberne, H. J., Kok, W. E. M., Tepaske, R., Cocchieri, R., Kemper, E. M., Teerlink, T., Jonker, M. A., Wisselink, W., De Mol, B. A. J. M. & van Leeuwen, P. A. M., 2014, In : American Journal of Clinical Nutrition. 99, 6, p. 1440-1449

Research output: Contribution to journalArticleAcademicpeer-review

Standard vs enriched high protein enteral nutrition in the ICU

Buijs, N. & van Leeuwen, P. A. M., 2014, In : JAMA. 312, 21, p. 2288-2289

Research output: Contribution to journalArticleAcademicpeer-review

The effect of fibers on coagulation of casein-based enteral nutrition in an artificial gastric digestion model

Luttikhold, J., van Norren, K., Minor, M., Buijs, N., van den Braak, C. C., Ludwig, T., Abrahamse, E., Rijnae, H. & van Leeuwen, P. A. M., 2014, In : Food & function. 5, 8, p. 1866-1871

Research output: Contribution to journalArticleAcademicpeer-review

2013

Cardiac Surgery-Specific Screening Tool Identifies Preoperative Undernutrition in Cardiac Surgery

van Venrooij, L. M. W., Visser, M., van Leeuwen, P. A. M., Peters, R. J. G. & De Mol, B. A. J. M., 2013, In : The Annals of Thoracic Surgery. 95, 2, p. 642-647

Research output: Contribution to journalArticleAcademicpeer-review

Feasibility of Intermittent Fish Oil Infusions in Outpatients with Graft- Versus-Host Disease of the Digestive Tract

van der Meij, B. S., Visser, O. J., Langius, J. A. E., Hacquebard, M. & van Leeuwen, P. A. M., 2013, In : Journal of Nutrition & Food Sciences. 03, 03, 1000201.

Research output: Contribution to journalArticleAcademicpeer-review

Glutamine and Antioxidants in Critically Ill Patients

Buijs, N., Vermeulen, M. A. R. & van Leeuwen, P. A. M., 2013, In : New England Journal of Medicine. 369, 5, p. 484-484

Research output: Contribution to journalArticleAcademicpeer-review

Novel nutritional substrates in surgery

Buijs, N., Worner, E. A., Brinkmann, S. J. H., Luttikhold, J., van der Meij, B. S., Houdijk, A. P. J. & van Leeuwen, P. A. M., 2013, In : Proceedings of the Nutrition Society. 72, 3, p. 277-287

Research output: Contribution to journalArticleAcademicpeer-review

Nutritional support in patients with GVHD of the digestive tract: state of the art

van der Meij, B. S., de Graaf, P., Wierdsma, N. J., Langius, J. A. E., Janssen, J. J. W. M., van Leeuwen, P. A. M. & Visser, O. J., 2013, In : Bone Marrow Transplantation. 48, 4, p. 474-482

Research output: Contribution to journalArticleAcademicpeer-review

Pre-cachexia and cachexia at diagnosis of stage III non-small-cell lung carcinoma: an exploratory study comparing two consensus-based frameworks

van der Meij, B. S., Schoonbeek, C. P., Smit, E. F., Muscaritoli, M., van Leeuwen, P. A. M. & Langius, J. A. E., 2013, In : British Journal of Nutrition. 109, 12, p. 2231-2239

Research output: Contribution to journalArticleAcademicpeer-review

Preoperative Nutrition Status and Postoperative Outcome in Elderly General Surgery Patients: A Systematic Review

van Stijn, M. F. M., Korkic-Halilovic, I., Bakker, M. S. M., van der Ploeg, T., van Leeuwen, P. A. M. & Houdijk, A. P. J., 2013, In : Journal of Parenteral and Enteral Nutition. 37, 1, p. 37-43

Research output: Contribution to journalArticleAcademicpeer-review

Preservation of the gut by preoperative carbohydrate loading improves postoperative food intake

Luttikhold, J., Oosting, A., van den Braak, C. C. M., van Norren, K., Rijna, H., van Leeuwen, P. A. M. & Bouritius, H., 2013, In : Clinical Nutrition. 32, 4, p. 556-561

Research output: Contribution to journalArticleAcademicpeer-review

Review article: the role of gastrointestinal hormones in the treatment of delayed gastric emptying in critically ill patients

Luttikhold, J., de Ruijter, F. M., van Norren, K., Diamant, M., Witkamp, R. F., van Leeuwen, P. A. M. & Vermeulen, M. A. R., 2013, In : Alimentary Pharmacology and Therapeutics. 38, 6, p. 573-583

Research output: Contribution to journalArticleAcademicpeer-review

Sarcopenic obesity is associated with adverse clinical outcome after cardiac surgery

Visser, M., van Venrooij, L. M. W., Vulperhorst, L., de Vos, R., Wisselink, W., van Leeuwen, P. A. M. & De Mol, B. A. J. M., 2013, In : Nutrition, Metabolism and Cardiovascular Diseases. 23, 6, p. 511-518

Research output: Contribution to journalArticleAcademicpeer-review

Surgical management of melanoma: an EORTC Melanoma Group survey

Testori, A., Soteldo, J., Powell, B., Sales, F., Borgognoni, L., Rutkowski, P., Lejeune, F., van Leeuwen, P. A. M. & Eggermont, A., 2013, In : Ecancermedicalscience. 7, 294.

Research output: Contribution to journalArticleAcademicpeer-review

The effects of supplementation of n-3 polyunsaturated fatty acids on clinical outcome parameters in patients with cancer: a systematic review

van der Meij, B. S., Bauer, J. D., Isenring, E. A., Brown, T., Davidson, W. L., van Bokhorst-de van der Schueren, M. A. E., Langius, J. A. E. & van Leeuwen, P. A. M., 2013, In : OA Epidemiology. 2013, 1, p. 2-17

Research output: Contribution to journalArticleAcademicpeer-review

2012

Accurate perioperative flow measurement of the portal vein and hepatic and renal artery: A role for preoperative MRI?

Vermeulen, M. A. R., Melis, G. C., Buijsman, R., Siroen, M. P., van de Poll, M. C. G., Boelens, P. G., Dejong, C. H. C., van Schaik, C., Hofman, M. B. M. & van Leeuwen, P. A. M., 2012, In : European Journal of Radiology. 81, 9, p. 2042-2048

Research output: Contribution to journalArticleAcademicpeer-review

Arginina en Nutrición especializada.

Buijs, N., Marges, E. R., Visser, M. & van Leeuwen, P. A. M., 2012, Nutrición enteral y parenteral.. Santa Fé: McGraw-Hill Interamericana, p. 584-595

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic