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Research Output

2020

Toward identifying reproducible brain signatures of obsessive-compulsive profiles: rationale and methods for a new global initiative

Simpson, H. B., van den Heuvel, O. A., Miguel, E. C., Reddy, Y. C. J., Stein, D. J., Lewis-Fernández, R., Shavitt, R. G., Lochner, C., Pouwels, P. J. W., Narayanawamy, J. C., Venkatasubramanian, G., Hezel, D. M., Vriend, C., Batistuzzo, M. C., Hoexter, M. Q., de Joode, N. T., Costa, D. L., de Mathis, M. A., Sheshachala, K., Narayan, M. & 15 others, van Balkom, A. J. L. M., Batelaan, N. M., Venkataram, S., Cherian, A., Marincowitz, C., Pannekoek, N., Stovezky, Y. R., Mare, K., Liu, F., Otaduy, M. C. G., Pastorello, B., Rao, R., Katechis, M., Van Meter, P. & Wall, M., 14 Feb 2020, In : BMC Psychiatry. 20, 1, p. 68 68.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2019
Open Access

Correction to: Relevance of neuroimaging for neurocognitive and behavioral outcome after pediatric traumatic brain injury (Brain Imaging and Behavior, (2018), 12, 1, (29-43), 10.1007/s11682-017-9673-3)

Königs, M., Pouwels, P. J., Ernest van Heurn, L., Bakx, R., Jeroen Vermeulen, R., Goslings, J., Poll-The, B. T., van der Wees, M., Catsman-Berrevoets, C. E. & Oosterlaan, J., 15 Aug 2019, In : Brain Imaging and Behavior. 13, 4, p. 1183-1183 1 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

Cortical atrophy accelerates as cognitive decline worsens in multiple sclerosis

Eijlers, A. J. C., Dekker, I., Steenwijk, M. D., Meijer, K. A., Hulst, H. E., Pouwels, P. J. W., Uitdehaag, B. M. J., Barkhof, F., Vrenken, H., Schoonheim, M. M. & Geurts, J. J. G., 1 Oct 2019, In : Neurology. 93, 14, p. e1348-e1359

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Fronto-limbic disconnection in patients with multiple sclerosis and depression

van Geest, Q., Boeschoten, R. E., Keijzer, M. J., Steenwijk, M. D., Pouwels, P. J., Twisk, J. W., Smit, J. H., Uitdehaag, B. M., Geurts, J. J., van Oppen, P. & Hulst, H. E., 1 Apr 2019, In : Multiple Sclerosis. 25, p. 715-726

Research output: Contribution to journalArticleAcademicpeer-review

GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay

Rumping, L., Tessadori, F., Pouwels, P. J. W., Vringer, E., Wijnen, J. P., Bhogal, A. A., Savelberg, S. M. C., Duran, K. J., Bakkers, M. J. G., Ramos, R. B. J. J., Schellekens, P. A. W., Kroes, H. Y., Klomp, D. W. J., Black, G. C. M., Taylor, R. L., Bakkers, J. P. W., Prinsen, H. C. M. T., van der Knaap, M. S., Dansen, T. B., Rehmann, H. & 6 others, Zwartkruis, F. J. T., Houwen, R. H. J., van Haaften, G., Verhoeven-Duif, N. M., Jans, J. J. M. & van Hasselt, P. M., 2019, In : Human Molecular Genetics. 28, 1, p. 96-104

Research output: Contribution to journalArticleAcademicpeer-review

Oculodentodigital dysplasia: A hypomyelinating leukodystrophy with a characteristic MRI pattern of brain stem involvement

Harting, I., Karch, S., Moog, U., Seitz, A., Pouwels, P. J. W. & Wolf, N. I., 1 Jan 2019, In : American Journal of Neuroradiology. 40, 5, p. 903-907 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Quantitative parametric maps of O-(2-[18F]fluoroethyl)-L-tyrosine kinetics in diffuse glioma

Koopman, T., Verburg, N., Pouwels, P. J. W., Wesseling, P., Hoekstra, O. S., De Witt Hamer, P. C., Lammertsma, A. A., Yaqub, M. & Boellaard, R., 2019, (Accepted/In press) In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Spectroscopic detection of brain propylene glycol in neonates: Effects of different pharmaceutical formulations of phenobarbital

Pouwels, P. J. W., van de Lagemaat, M., van de Pol, L. A., Witjes, B. C. M. & Zonnenberg, I. A., 2019, In : Journal of magnetic resonance imaging : JMRI. 49, 4, p. 1062-1068

Research output: Contribution to journalArticleAcademicpeer-review

Structural network topology relates to tissue properties in multiple sclerosis

Kiljan, S., Meijer, K. A., Steenwijk, M. D., Pouwels, P. J. W., Schoonheim, M. M., Schenk, G. J., Geurts, J. J. G. & Douw, L., 25 Jan 2019, In : Journal of Neurology. 266, 1, p. 212-222

Research output: Contribution to journalArticleAcademicpeer-review

Thalamus atrophy progresses faster in subjects with early MS who have more damage in the connected white matter and who show increasing disability over time

Weeda, M. M., Pruis, I. J., Brouwer, I., Bellenberg, B., Schneider, R., Lukas, C., Barkhof, F., Vrenken, H. & Pouwels, P. J. W., Sep 2019, In : Multiple Sclerosis Journal. 25, p. 689-690

Research output: Contribution to journalMeeting AbstractAcademic

Open Access
2018

4H Leukodystrophy: Lessons from 3T Imaging

Cayami, F. K., Bugiani, M., Pouwels, P. J. W., Bernard, G., van der Knaap, M. S. & Wolf, N. I., Apr 2018, In : Neuropediatrics. 49, 2, p. 112-117

Research output: Contribution to journalArticleAcademicpeer-review

9.4T and 17.6T MRI of Retinoblastoma: Ex Vivo evaluation of microstructural anatomy and disease extent compared with histopathology

de Jong, M. C., de Graaf, P., Pouwels, P. J. W., Beenakker, J. W., Jansen, R. W., Geurts, J. J. G., Moll, A. C., Castelijns, J. A., van der Valk, P. & van der Weerd, L., 1 Jun 2018, In : Journal of Magnetic Resonance Imaging. p. 1487-1497 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Diffusion tensor imaging in metachromatic leukodystrophy

van Rappard, D. F., Königs, M., Steenweg, M. E., Boelens, J. J., Oosterlaan, J., van der Knaap, M. S., Wolf, N. I. & Pouwels, P. J. W., 1 Mar 2018, In : Journal of Neurology. 265, 3, p. 659-668 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

High reproducibility and robustness to lesions, but large software and scanner effects for mean upper cervical cord area (MUCCA) measurement in MS

Middelkoop, S., Weeda, M. M., Steenwijk, M. D., Daams, M., Amiri, H., Brouwer, I., Killestein, J., Uitdehaag, B. M. J., Dekker, I., Lukas, C., Bellenberg, B., Barkhof, F., Pouwels, P. J. W. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 853-854

Research output: Contribution to journalMeeting AbstractAcademic

Metabolites predict lesion formation and severity in relapsing-remitting multiple sclerosis

Klauser, A. M., Wiebenga, O. T., Eijlers, A. J., Schoonheim, M. M., Uitdehaag, B. M., Barkhof, F., Pouwels, P. J. & Geurts, J. J., Apr 2018, In : Multiple Sclerosis. p. 1352458517702534

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Quantitative MR spectroscopic imaging in metachromatic leukodystrophy: value for prognosis and treatment

van Rappard, D. F., Klauser, A., Steenweg, M. E., Boelens, J. J., Bugiani, M., van der Knaap, M. S., Wolf, N. I. & Pouwels, P. J. W., 1 Jan 2018, In : Journal of Neurology, Neurosurgery and Psychiatry. p. 105-111 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Relevance of neuroimaging for neurocognitive and behavioral outcome after pediatric traumatic brain injury

Königs, M., Pouwels, P. JW., Ernest van Heurn, LW., Bakx, R., Jeroen Vermeulen, R., Carel Goslings, J., Poll-The, B. T., van der Wees, M., Catsman-Berrevoets, C. E. & Oosterlaan, J., Feb 2018, In : Brain Imaging and Behavior. 12, 1, p. 1-15 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

4H Leukodystrophy: A Brain Magnetic Resonance Imaging Scoring System

Vrij-Van Den Bos, S., Hol, J. A., La Piana, R., Harting, I., Vanderver, A., Barkhof, F., Cayami, F., Van Wieringen, W. N., Pouwels, P. J. W., Van Der Knaap, M. S., Bernard, G. & Wolf, N. I., 1 Jun 2017, In : Neuropediatrics. 48, 3, p. 152-160 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Connectomic profile and clinical phenotype in newly diagnosed glioma patients

Derks, J., Dirkson, A. R., de Witt Hamer, P. C., van Geest, Q., Hulst, H. E., Barkhof, F., Pouwels, P. J. W., Geurts, J. J. G., Reijneveld, J. C. & Douw, L., 2017, In : NeuroImage: Clinical. 14, p. 87-96 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Creatine in the central nervous system: From magnetic resonance spectroscopy to creatine deficiencies

Rackayova, V., Cudalbu, C., Pouwels, P. J. W. & Braissant, O., 15 Jul 2017, In : Analytical Biochemistry. 529, p. 144-157 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Depression in multiple sclerosis: structural and functional disconnection in the fronto-limbic system

van Geest, Q., Boeschoten, R. E., Keijzer, M. J., Steenwijk, M. D., Pouwels, P. J. W., Smit, J. H., Uitdehaag, B. M. J., Geurts, J. J. G., van Oppen, P. & Hulst, H. E., Oct 2017, In : Multiple Sclerosis Journal. 23, p. 538-539

Research output: Contribution to journalMeeting AbstractAcademic

Diagnostic Accuracy of Neuroimaging to Delineate Diffuse Gliomas within the Brain: A Meta-Analysis

Verburg, N., Hoefnagels, F. W. A., Barkhof, F., Boellaard, R., Goldman, S., Guo, J., Heimans, J. J., Hoekstra, O. S., Jain, R., Kinoshita, M., Pouwels, P. J. W., Price, S. J., Reijneveld, J. C., Stadlbauer, A., Vandertop, W. P., Wesseling, P., Zwinderman, A. H. & De Witt Hamer, P. C., Oct 2017, In : American Journal of Neuroradiology. 38, 10, p. 1884-1891 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Disrupted white matter structural networks in healthy older adult APOE ε4 carriers – An international multicenter DTI study

Cavedo, E., Lista, S., Rojkova, K., Chiesa, P. A., Houot, M., Brueggen, K., Blautzik, J., Bokde, A. L. W., Dubois, B., Barkhof, F., Pouwels, P. J. W., Teipel, S., Hampel, H. & Alzheimer Precision Medicine Initiative (APMI), 15 Aug 2017, In : Neuroscience. 357, p. 119-133 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Fronto-limbic structural and functional changes and depression in multiple sclerosis: is there a relationship with cognition?

van Geest, Q., Boeschoten, R. E., Keijzer, M. J., Steenwijk, M. D., Pouwels, P. J. W., Smit, J. H., Uitdehaag, B. M. J., Van Oppen, P., Geurts, J. J. G. & Hulst, H. E., Jul 2017, In : Multiple Sclerosis Journal. 23, 8, p. NP3-NP3

Research output: Contribution to journalMeeting AbstractAcademic

Pancreatic Steatosis Is Not Associated with Exocrine Pancreatic Function in Overweight Type 2 Diabetes Patients

Vendrik, K. E. W., Tonneijck, L., Muskiet, M. H. A., Kramer, M. H. H., Pouwels, P. J. W., Pieters-Van Den Bos, I. C., Diamant, M., Cahen, D. L., Van Raalte, D. H. & Smits, M. M., 1 Oct 2017, In : Pancreas. 46, 9, p. e75-e76

Research output: Contribution to journalLetterAcademicpeer-review

Performance of five research-domain automated WM lesion segmentation methods in a multi-center MS study

de Sitter, A., Steenwijk, M. D., Ruet, A., Versteeg, A., Liu, Y., van Schijndel, R. A., Pouwels, P. J. W., Kilsdonk, I. D., Cover, K. S., van Dijk, B. W., Ropele, S., Rocca, M. A., Yiannakas, M., Wattjes, M. P., Damangir, S., Frisoni, G. B., Sastre-Garriga, J., Rovira, A., Enzinger, C., Filippi, M. & 7 others, Frederiksen, J. L., Ciccarelli, O., Kappos, L., Barkhof, F., Vrenken, H., MAGNIMS Study Group & neuGRID, 1 Dec 2017, In : NeuroImage. 163, p. 106-114 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Sex Differences in White Matter Microstructure in the Human Brain Predominantly Reflect Differences in Sex Hormone Exposure

Van Hemmen, J., Saris, I. M. J., Cohen-Kettenis, P. T., Veltman, D. J., Pouwels, P. J. W. & Bakker, J., 1 May 2017, In : Cerebral Cortex. 27, 5, p. 2994-3001 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The European DTI Study on Dementia - A multicenter DTI and MRI study on Alzheimer's disease and Mild Cognitive Impairment

Brueggen, K., Grothe, M. J., Dyrba, M., Fellgiebel, A., Fischer, F., Filippi, M., Agosta, F., Nestor, P., Meisenzahl, E., Blautzik, J., Frölich, L., Hausner, L., Bokde, A. L. W., Frisoni, G., Pievani, M., Klöppel, S., Prvulovic, D., Barkhof, F., Pouwels, P. J. W., Schröder, J. & 3 others, Hampel, H., Hauenstein, K. & Teipel, S., Jan 2017, In : NeuroImage. 144, Pt B, p. 305-308 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

The structural connectome of children with traumatic brain injury

Königs, M., van Heurn, L. W. E., Bakx, R., Vermeulen, R. J., Goslings, J. C., Poll-The, B. T., van der Wees, M., Catsman-Berrevoets, C. E., Oosterlaan, J. & Pouwels, P. J. W., 2017, (Accepted/In press) In : Human Brain Mapping.

Research output: Contribution to journalArticleAcademicpeer-review

Efficacy of hematopoietic cell transplantation in metachromatic leukodystrophy: the Dutch experience

van Rappard, D. F., Boelens, J. J., van Egmond, M. E., Kuball, J., van Hasselt, P. M., Oostrom, K. J., Pouwels, P. J. W., van der Knaap, M. S., Hollak, C. E. M. & Wolf, N. I., 16 Jun 2016, In : Blood. 127, 24, p. 3098-3101

Research output: Contribution to journalArticleAcademicpeer-review

HIGHER FUNCTIONAL HUB LOAD AT DIAGNOSIS IS ASSOCIATED WITH SHORTER SURVIVAL IN GLIOMA PATIENTS

Derks, J., Dirkson, A., Hamer, P. C. D. W., Van Geest, Q., Hulst, H. E., Barkhof, F., Pouwels, P. J. W., Geurts, J. J. G., Reijneveld, J. C. & Douw, L., Oct 2016, In : Neuro-Oncology. 18, p. 35-35

Research output: Contribution to journalMeeting AbstractOther research output

Increased cortical grey matter lesion detection in multiple sclerosis with 7 T MRI: a post-mortem verification study

Kilsdonk, I. D., Jonkman, L. E., Klaver, R., van Veluw, S. J., Zwanenburg, J. J. M., Kuijer, J. P. A., Pouwels, P. J. W., Twisk, J. W. R., Wattjes, M. P., Luijten, P. R., Barkhof, F. & Geurts, J. J. G., 1 May 2016, In : Brain. 139, p. 1472-1481

Research output: Contribution to journalArticleAcademicpeer-review

Quantitative MRI in hypomyelinating disorders: Correlation with motor handicap

Steenweg, M. E., Wolf, N. I., van Wieringen, W. N., Barkhof, F., van der Knaap, M. S. & Pouwels, P. J. W., 23 Aug 2016, In : Neurology. 87, 8, p. 752-758

Research output: Contribution to journalArticleAcademicpeer-review