If you made any changes in Pure these will be visible here soon.

Research Output 1989 2019

2014

Pathogenesis of multiple sclerosis: insights from molecular and metabolic imaging

Ciccarelli, O., Barkhof, F., Bodini, B., De Stefano, N., Golay, X., Nicolay, K., Pelletier, D., Pouwels, P. J. W., Smith, S. A., Wheeler-Kingshott, C. A. M., Stankoff, B., Yousry, T. & Miller, D. H., 2014, In : Lancet Neurology. 13, 8, p. 807-822

Research output: Contribution to journalArticleAcademicpeer-review

Sex-specific extent and severity of white matter damage in multiple sclerosis: Implications for cognitive decline

Schoonheim, M. M., Vigeveno, R. M., Lopes, F. C. R., Pouwels, P. J. W., Polman, C. H., Barkhof, F. & Geurts, J. J. G., 2014, In : Human Brain Mapping. 35, 5, p. 2348-2358

Research output: Contribution to journalArticleAcademicpeer-review

What Explains Gray Matter Atrophy in Long-standing Multiple Sclerosis?

Steenwijk, M. D., Daams, M., Pouwels, P. J. W., Balk, L. J., Tewarie, P. K., Killestein, J., Uitdehaag, B. M. J., Geurts, J. J. G., Barkhof, F. & Vrenken, H., 2014, In : Radiology. 272, 3, p. 832-842

Research output: Contribution to journalArticleAcademicpeer-review

2015

Childhood white matter disorders: Research at the interface of MRI, clinical phenotype and genetics

Steenweg, M. E., 2015

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

Diffusion-Weighted Imaging of the Head and Neck in Healthy Subjects: Reproducibility of ADC Values in Different MRI Systems and Repeat Sessions

Kolff-Gart, A. S., Pouwels, P. J. W., Noij, D. P., Ljumanovic, R., Vandecaveye, V., de Keyzer, F., de Bree, R., de Graaf, P., Knol, D. L. & Castelijns, J. A., 2015, In : American Journal of Neuroradiology. 36, 2, p. 384-390

Research output: Contribution to journalArticleAcademicpeer-review

H-1-MRS in glutaric aciduria type 1: impact of biochemical phenotype and age on the cerebral accumulation of neurotoxic metabolites

Harting, I., Boy, N., Heringer, J., Seitz, A., Bendszus, M., Pouwels, P. J. W. & Kolker, S., 2015, In : Journal of Inherited Metabolic Disease. 38, 5, p. 829-838

Research output: Contribution to journalArticleAcademicpeer-review

Joint assessment of white matter integrity, cortical and subcortical atrophy to distinguish AD from behavioral variant FTD: A two-center study

Moller, C., Hafkemeijer, A., Pijnenburg, Y. A., Rombouts, S. A. R. B., van der Grond, J., Dopper, E. G. P., van Swieten, J. C., Versteeg, A., Pouwels, P. J. W., Barkhof, F., Scheltens, P., Vrenken, H. & van der Flier, W. M., 2015, In : NeuroImage: Clinical. 9, p. 418-429

Research output: Contribution to journalArticleAcademicpeer-review

Perivascular spaces in MS patients at 7 Tesla MRI: A marker of neurodegeneration?

Kilsdonk, I. D., Steenwijk, M. D., Pouwels, P. J. W., Zwanenburg, J. J. M., Visser, F., Luijten, P. R., Geurts, J. J. G., Barkhof, F. & Wattjes, M. P., 2015, In : Multiple Sclerosis. 21, 2, p. 155-162

Research output: Contribution to journalArticleAcademicpeer-review

Predictive value of diffusion-weighted imaging without and with including contrast-enhanced magnetic resonance imaging in image analysis of head and neck squamous cell carcinoma

Noij, D. P., Pouwels, P. J. W., Ljumanovic, R., Knol, D. L., Doornaert, P., de Bree, R., Castelijns, J. A. & de Graaf, P., 2015, In : European Journal of Radiology. 84, 1, p. 108-116

Research output: Contribution to journalArticleAcademicpeer-review

Volumetric MRI data correlate to disease severity in metachromatic leukodystrophy

Tillema, J. M., Derks, M. G. M., Pouwels, P. J. W., de Graaf, P., van Rappard, D. F., Barkhof, F., Steenweg, M. E., van der Knaap, M. S. & Wolf, N. I., 2015, In : Annals of Clinical and Translational Neurology. 2, 9, p. 932-940

Research output: Contribution to journalArticleAcademicpeer-review

Efficacy of hematopoietic cell transplantation in metachromatic leukodystrophy: the Dutch experience

van Rappard, D. F., Boelens, J. J., van Egmond, M. E., Kuball, J., van Hasselt, P. M., Oostrom, K. J., Pouwels, P. J. W., van der Knaap, M. S., Hollak, C. E. M. & Wolf, N. I., 16 Jun 2016, In : Blood. 127, 24, p. 3098-3101

Research output: Contribution to journalArticleAcademicpeer-review

HIGHER FUNCTIONAL HUB LOAD AT DIAGNOSIS IS ASSOCIATED WITH SHORTER SURVIVAL IN GLIOMA PATIENTS

Derks, J., Dirkson, A., Hamer, P. C. D. W., Van Geest, Q., Hulst, H. E., Barkhof, F., Pouwels, P. J. W., Geurts, J. J. G., Reijneveld, J. C. & Douw, L., Oct 2016, In : Neuro-Oncology. 18, p. 35-35

Research output: Contribution to journalMeeting AbstractOther research output

Increased cortical grey matter lesion detection in multiple sclerosis with 7 T MRI: a post-mortem verification study

Kilsdonk, I. D., Jonkman, L. E., Klaver, R., van Veluw, S. J., Zwanenburg, J. J. M., Kuijer, J. P. A., Pouwels, P. J. W., Twisk, J. W. R., Wattjes, M. P., Luijten, P. R., Barkhof, F. & Geurts, J. J. G., 1 May 2016, In : Brain. 139, p. 1472-1481

Research output: Contribution to journalArticleAcademicpeer-review

476 Downloads (Pure)

Looking through the macroscope: 7 Tesla MRI in multiple sclerosis

Kilsdonk, I. D., 2016

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File

Quantitative MRI in hypomyelinating disorders: Correlation with motor handicap

Steenweg, M. E., Wolf, N. I., van Wieringen, W. N., Barkhof, F., van der Knaap, M. S. & Pouwels, P. J. W., 23 Aug 2016, In : Neurology. 87, 8, p. 752-758

Research output: Contribution to journalArticleAcademicpeer-review

TS-EUROTRAIN: A European-Wide Investigation and Training Network on the Etiology and Pathophysiology of de la Tourette Syndrome

Forde, N. J., Kanaan, A. S., Widomska, J., Padmanabhuni, S. S., Nespoli, E., Alexander, J., Arranz, J. I. R., Fan, S., Houssari, R., Nawaz, M. S., Rizzo, F., Pagliaroli, L., Zilhao, N. R., Aranyi, T., Barta, C., Boeckers, T. M., Boomsma, D. I., Buisman, W. R., Buitelaar, J. K., Cath, D. & 22 othersDietrich, A., Driessen, N., Drineas, P., Dunlap, M., Gerasch, S., Glennon, J., Hengerer, B., van den Heuvel, O. A., Jespersgaard, C., Moeller, H. E., Mueller-Vahl, K. R., Openneer, T. J. C., Poelmans, G., Pouwels, P. J. W., Scharf, J. M., Stefansson, H., Tumer, Z., Veltman, D. J., van der werf, Y. D., Hoekstra, P. J., Ludolph, A. & Paschou, P., 23 Aug 2016, In : Frontiers in Neuroscience. 10

Research output: Contribution to journalArticleAcademicpeer-review

49 Downloads (Pure)

Understanding the shrinking brain in multiple sclerosis: multimodal MRI studies

Steenwijk, M. D., 2016

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File
2017

4H Leukodystrophy: A Brain Magnetic Resonance Imaging Scoring System

Vrij-Van Den Bos, S., Hol, J. A., La Piana, R., Harting, I., Vanderver, A., Barkhof, F., Cayami, F., Van Wieringen, W. N., Pouwels, P. J. W., Van Der Knaap, M. S., Bernard, G. & Wolf, N. I., 1 Jun 2017, In : Neuropediatrics. 48, 3, p. 152-160 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Connectomic profile and clinical phenotype in newly diagnosed glioma patients

Derks, J., Dirkson, A. R., de Witt Hamer, P. C., van Geest, Q., Hulst, H. E., Barkhof, F., Pouwels, P. J. W., Geurts, J. J. G., Reijneveld, J. C. & Douw, L., 2017, In : NeuroImage: Clinical. 14, p. 87-96 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Creatine in the central nervous system: From magnetic resonance spectroscopy to creatine deficiencies

Rackayova, V., Cudalbu, C., Pouwels, P. J. W. & Braissant, O., 15 Jul 2017, In : Analytical Biochemistry. 529, p. 144-157 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Depression in multiple sclerosis: structural and functional disconnection in the fronto-limbic system

van Geest, Q., Boeschoten, R. E., Keijzer, M. J., Steenwijk, M. D., Pouwels, P. J. W., Smit, J. H., Uitdehaag, B. M. J., Geurts, J. J. G., van Oppen, P. & Hulst, H. E., Oct 2017, In : Multiple Sclerosis Journal. 23, p. 538-539

Research output: Contribution to journalMeeting AbstractAcademic

Diagnostic Accuracy of Neuroimaging to Delineate Diffuse Gliomas within the Brain: A Meta-Analysis

Verburg, N., Hoefnagels, F. W. A., Barkhof, F., Boellaard, R., Goldman, S., Guo, J., Heimans, J. J., Hoekstra, O. S., Jain, R., Kinoshita, M., Pouwels, P. J. W., Price, S. J., Reijneveld, J. C., Stadlbauer, A., Vandertop, W. P., Wesseling, P., Zwinderman, A. H. & De Witt Hamer, P. C., Oct 2017, In : American Journal of Neuroradiology. 38, 10, p. 1884-1891 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Disrupted white matter structural networks in healthy older adult APOE ε4 carriers – An international multicenter DTI study

Cavedo, E., Lista, S., Rojkova, K., Chiesa, P. A., Houot, M., Brueggen, K., Blautzik, J., Bokde, A. L. W., Dubois, B., Barkhof, F., Pouwels, P. J. W., Teipel, S., Hampel, H. & Alzheimer Precision Medicine Initiative (APMI), 15 Aug 2017, In : Neuroscience. 357, p. 119-133 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Fronto-limbic structural and functional changes and depression in multiple sclerosis: is there a relationship with cognition?

van Geest, Q., Boeschoten, R. E., Keijzer, M. J., Steenwijk, M. D., Pouwels, P. J. W., Smit, J. H., Uitdehaag, B. M. J., Van Oppen, P., Geurts, J. J. G. & Hulst, H. E., Jul 2017, In : Multiple Sclerosis Journal. 23, 8, p. NP3-NP3

Research output: Contribution to journalMeeting AbstractAcademic

Pancreatic Steatosis Is Not Associated with Exocrine Pancreatic Function in Overweight Type 2 Diabetes Patients

Vendrik, K. E. W., Tonneijck, L., Muskiet, M. H. A., Kramer, M. H. H., Pouwels, P. J. W., Pieters-Van Den Bos, I. C., Diamant, M., Cahen, D. L., Van Raalte, D. H. & Smits, M. M., 1 Oct 2017, In : Pancreas. 46, 9, p. e75-e76

Research output: Contribution to journalLetterAcademicpeer-review

Performance of five research-domain automated WM lesion segmentation methods in a multi-center MS study

de Sitter, A., Steenwijk, M. D., Ruet, A., Versteeg, A., Liu, Y., van Schijndel, R. A., Pouwels, P. J. W., Kilsdonk, I. D., Cover, K. S., van Dijk, B. W., Ropele, S., Rocca, M. A., Yiannakas, M., Wattjes, M. P., Damangir, S., Frisoni, G. B., Sastre-Garriga, J., Rovira, A., Enzinger, C., Filippi, M. & 7 othersFrederiksen, J. L., Ciccarelli, O., Kappos, L., Barkhof, F., Vrenken, H., MAGNIMS Study Group & neuGRID, 1 Dec 2017, In : NeuroImage. 163, p. 106-114 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Sex Differences in White Matter Microstructure in the Human Brain Predominantly Reflect Differences in Sex Hormone Exposure

Van Hemmen, J., Saris, I. M. J., Cohen-Kettenis, P. T., Veltman, D. J., Pouwels, P. J. W. & Bakker, J., 1 May 2017, In : Cerebral Cortex. 27, 5, p. 2994-3001 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The European DTI Study on Dementia - A multicenter DTI and MRI study on Alzheimer's disease and Mild Cognitive Impairment

Brueggen, K., Grothe, M. J., Dyrba, M., Fellgiebel, A., Fischer, F., Filippi, M., Agosta, F., Nestor, P., Meisenzahl, E., Blautzik, J., Frölich, L., Hausner, L., Bokde, A. L. W., Frisoni, G., Pievani, M., Klöppel, S., Prvulovic, D., Barkhof, F., Pouwels, P. J. W., Schröder, J. & 3 othersHampel, H., Hauenstein, K. & Teipel, S., Jan 2017, In : NeuroImage. 144, Pt B, p. 305-308 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

The structural connectome of children with traumatic brain injury

Königs, M., van Heurn, L. W. E., Bakx, R., Vermeulen, R. J., Goslings, J. C., Poll-The, B. T., van der Wees, M., Catsman-Berrevoets, C. E., Oosterlaan, J. & Pouwels, P. J. W., 2017, (Accepted/In press) In : Human Brain Mapping.

Research output: Contribution to journalArticleAcademicpeer-review

2018

4H Leukodystrophy: Lessons from 3T Imaging

Cayami, F. K., Bugiani, M., Pouwels, P. J. W., Bernard, G., van der Knaap, M. S. & Wolf, N. I., Apr 2018, In : Neuropediatrics. 49, 2, p. 112-117

Research output: Contribution to journalArticleAcademicpeer-review

9.4T and 17.6T MRI of Retinoblastoma: Ex Vivo evaluation of microstructural anatomy and disease extent compared with histopathology

de Jong, M. C., de Graaf, P., Pouwels, P. J. W., Beenakker, J. W., Jansen, R. W., Geurts, J. J. G., Moll, A. C., Castelijns, J. A., van der Valk, P. & van der Weerd, L., 1 Jun 2018, In : Journal of Magnetic Resonance Imaging. p. 1487-1497 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Correction to: Relevance of neuroimaging for neurocognitive and behavioral outcome after pediatric traumatic brain injury (Brain Imaging and Behavior, (2018), 12, 1, (29-43), 10.1007/s11682-017-9673-3)

Königs, M., Pouwels, P. J., Ernest van Heurn, L., Bakx, R., Jeroen Vermeulen, R., Goslings, J., Poll-The, B. T., van der Wees, M., Catsman-Berrevoets, C. E. & Oosterlaan, J., 1 Jan 2018, (Accepted/In press) In : Brain Imaging and Behavior.

Research output: Contribution to journalArticleAcademicpeer-review

Diffusion tensor imaging in metachromatic leukodystrophy

van Rappard, D. F., Königs, M., Steenweg, M. E., Boelens, J. J., Oosterlaan, J., van der Knaap, M. S., Wolf, N. I. & Pouwels, P. J. W., 1 Mar 2018, In : Journal of Neurology. 265, 3, p. 659-668 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Fronto-limbic disconnection in patients with multiple sclerosis and depression

van Geest, Q., Boeschoten, R. E., Keijzer, M. J., Steenwijk, M. D., Pouwels, P. J., Twisk, J. W., Smit, J. H., Uitdehaag, B. M., Geurts, J. J., van Oppen, P. & Hulst, H. E., 1 Mar 2018, In : Multiple Sclerosis. p. 1352458518767051

Research output: Contribution to journalArticleAcademicpeer-review