20062019
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Research Output 2006 2019

  • 12 Article
  • 1 Research VU University Amsterdam, graduation VU University Amsterdam

Binding characterization of N-(2-chloro-5-thiomethylphenyl)-N′-(3-[ 3 H] 3 methoxy phenyl)-N′-methylguanidine ([ 3 H]GMOM), a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist

Metaxas, A., van Berckel, B. N. M., Klein, P. J., Verbeek, J., Nash, E. C., Kooijman, E. J. M., Renjaän, V. R. A., Golla, S. S. V., Boellaard, R., Christiaans, J. A. M., Windhorst, A. D. & Leysen, J. E., 19 Feb 2019, In : Pharmacology Research and Perspectives. 7, 1, e00458.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Synthesis, radiolabelling and preclinical evaluation of novel NMDA ligands as potential tracers for positron emission tomography

Klein, PJ., 2 Apr 2019, 199 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

First in human evaluation of [18F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors

van der Aart, J., Golla, S. S. V., van der Pluijm, M., Schwarte, L. A., Schuit, R. C., Klein, P. J., Metaxas, A., Windhorst, A. D., Boellaard, R., Lammertsma, A. A. & van Berckel, B. N. M., 1 Jan 2018, In : EJNMMI Research. 8, 69.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Synthesis, radiolabeling and preclinical evaluation of a [11C]GMOM derivative as PET radiotracer for the ion channel of the N-methyl-D-aspartate receptor

Klein, P. J., Schuit, R. C., Metaxas, A., Christiaans, J. AM., Kooijman, E., Lammertsma, A. A., van Berckel, B. NM. & Windhorst, A. D., 1 Aug 2017, In : Nuclear Medicine and Biology. 51, p. 25-32 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Quantification of the novel N-methyl-D-aspartate receptor ligand [C-11] GMOM in man

van der Doef, T. F., Golla, S. S. V., Klein, P. J., Oropeza-Seguias, G. M., Schuit, R. C., Metaxas, A., Jobse, E., Schwarte, L. A., Windhorst, A. D., Lammertsma, A. A., van Berckel, B. N. M. & Boellaard, R., Jun 2016, In : Journal of Cerebral Blood Flow and Metabolism. 36, 6, p. 1111-1121

Research output: Contribution to journalArticleAcademicpeer-review