Research Output per year
Research Output 2008 2019
- 1 - 50 out of 69 results
- Publication Year, Title (descending)
2019
Cardiac Microvascular Endothelial Enhancement of Cardiomyocyte Function Is Impaired by Inflammation and Restored by Empagliflozin
Juni, R. P., Kuster, D. W. D., Goebel, M., Helmes, M., Musters, R. J. P., van der Velden, J., Koolwijk, P., Paulus, W. J. & van Hinsbergh, V. W. M., 1 Sep 2019, In : JACC: Basic to Translational Science. 4, 5, p. 575-591Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Empagliflozin and Dapagliflozin Reduce ROS Generation and Restore NO Bioavailability in Tumor Necrosis Factor α-Stimulated Human Coronary Arterial Endothelial Cells
Uthman, L., Homayr, A., Juni, R. P., Spin, E. L., Kerindongo, R., Boomsma, M., Hollmann, M. W., Preckel, B., Koolwijk, P., van Hinsbergh, V. W. M., Zuurbier, C. J., Albrecht, M. & Weber, N. C., 2019, In : Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 53, 5, p. 865-886Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Evolution of heterotopic bone in fibrodysplasia ossificans progressiva: An [18F]NaF PET/CT study
Botman, E., Raijmakers, P. G. H. M., Yaqub, M., Teunissen, B., Netelenbos, C., Lubbers, W., Schwarte, L. A., Micha, D., Bravenboer, N., Schoenmaker, T., de Vries, T. J., Pals, G., Smit, J. M., Koolwijk, P., Trotter, D. G., Lammertsma, A. A. & Eekhoff, E. M. W., 1 Jul 2019, In : Bone. 124, p. 1-6Research output: Contribution to journal › Article › Academic › peer-review
IL-6 counteracts the inhibitory effect of IL-4 on osteogenic differentiation of human adipose stem cells
Bastidas-Coral, A. P., Hogervorst, J. M. A., Forouzanfar, T., Kleverlaan, C. J., Koolwijk, P., Klein-Nulend, J. & Bakker, A. D., 2019, In : Journal of Cellular Physiology. 234, 11, p. 20520-20532Research output: Contribution to journal › Article › Academic › peer-review
Indoxyl sulfate stimulates angiogenesis by regulating reactive oxygen species production via CYP1B1
Pei, J., Juni, R., Harakalova, M., Duncker, D. J., Asselbergs, F. W., Koolwijk, P., van Hinsbergh, V., Verhaar, M. C., Mokry, M. & Cheng, C., 2019, In : Toxins. 11, 8, 454.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension
Rol, N., de Raaf, M. A., Sun, X. Q., Kuiper, V. P., da Silva Gonçalves Bos, D., Happé, C., Kurakula, K., Dickhoff, C., Thuillet, R., Tu, L., Guignabert, C., Schalij, I., Lodder, K., Pan, X., Herrmann, F. E., van Nieuw Amerongen, G. P., Koolwijk, P., Vonk-Noordegraaf, A., de Man, F. S., Wollin, L. & 3 others, 2019, In : Cardiovascular Research. 115, 2, p. 432-439Research output: Contribution to journal › Article › Academic › peer-review
Open Access
The Potential Role of Neutrophil Gelatinase-Associated Lipocalin in the Development of Abdominal Aortic Aneurysms
Groeneveld, M. E., Struik, J. A., Musters, R. J. P., Tangelder, G. J., Koolwijk, P., Niessen, H. W., Hoksbergen, A. W. J., Wisselink, W. & Yeung, K. K., 2019, In : Annals of Vascular Surgery. 57, p. 210-219Research output: Contribution to journal › Article › Academic › peer-review
2018
A local uPAR-plasmin-TGFβ1 positive feedback loop in a qualitative computational model of angiogenic sprouting explains the in vitro effect of fibrinogen variants
Boas, S. E. M., Carvalho, J., van den Broek, M., Weijers, E. M., Goumans, M-J., Koolwijk, P. & Merks, R. M. H., 2018, In : PLoS Computational Biology. 14, 7, e1006239.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Blood Outgrowth and Proliferation of Endothelial Colony Forming Cells are Related to Markers of Disease Severity in Patients with Pulmonary Arterial Hypertension
Smits, J., Tasev, D., Andersen, S., Szulcek, R., Botros, L., Ringgaard, S., Andersen, A., Vonk-Noordegraaf, A., Koolwijk, P. & Bogaard, H. J., 2018, In : International Journal of Molecular Sciences. 19, 12Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Consensus guidelines for the use and interpretation of angiogenesis assays
Nowak-Sliwinska, P., Alitalo, K., Allen, E., Anisimov, A., Aplin, A. C., Auerbach, R., Augustin, H. G., Bates, D. O., van Beijnum, J. R., Bender, R. H. F., Bergers, G., Bikfalvi, A., Bischoff, J., Böck, B. C., Brooks, P. C., Bussolino, F., Cakir, B., Carmeliet, P., Castranova, D., Cimpean, A. M. & 66 others, 1 Aug 2018, In : Angiogenesis. 21, 3, p. 425-532 108 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access
Endothelial cells enhance adipose mesenchymal stromal cell-mediated matrix contraction via ALK receptors and reduced follistatin: Potential role of endothelial cells in skin fibrosis
Monsuur, H. N., van den Broek, L. J., Koolwijk, P., Niessen, F. B. & Gibbs, S., Oct 2018, In : Journal of Cellular Physiology. 233, 10, p. 6714-6722Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Endothelial Colony Forming Cells (ECFCs) for tissue regeneration: in vitro characterization
Tasev, D., 2018, 200 p.Research output: Thesis › Research VU University Amsterdam, graduation VU University Amsterdam › Academic
Folinic acid increases protein arginine methylation in human endothelial cells
Esse, R., Teerlink, T., Koolwijk, P., Tavares de Almeida, I., Blom, H. J. & Castro, R., 2018, In : Nutrients. 10, 4, 404.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Gestational diabetes alters microRNA signatures in human feto-placental endothelial cells depending on fetal sex
Strutz, J., Cvitic, S., Hackl, H., Kashofer, K., Appel, H. M., Thüringer, A., Desoye, G., Koolwijk, P. & Hiden, U., 2018, In : Clinical science (London, England : 1979). 132, 22, p. 2437-2449Research output: Contribution to journal › Article › Academic › peer-review
Hypoxia Impairs Initial Outgrowth of Endothelial Colony Forming Cells and Reduces Their Proliferative and Sprouting Potential
Tasev, D., Dekker-Vroling, L., van Wijhe, M., Broxterman, H. J., Koolwijk, P. & van Hinsbergh, V. W. M., 20 Dec 2018, In : Frontiers in medicine. 5, 356.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Outgrowth, proliferative speed and angiogenic capacity of Endothelial Colony Forming Cells (ECFC) correlate with disease severity and right ventricular (RV) adaptation in Pulmonary Arterial Hypertension (PAH) patients
Smits, J., Tasev, D., Szulcek, R., Andersen, S., Ringaard, S., Hyldebradt, J., Andersen, A., Vonk-Noordegraaf, A., Koolwijk, P. & Bogaard, H-J., 15 Sep 2018, In : European Respiratory Journal. 52Research output: Contribution to journal › Meeting Abstract › Academic
Understanding endothelial cell behavior for regenerative medicine strategies
Monsuur, H. N., 2018, 174 p.Research output: Thesis › Research VU University Amsterdam, graduation VU University Amsterdam › Academic
2017
HIF-2a regulates in vitro neovascularization during hypoxia
Nauta, TD., 2017, 206 p.Research output: Thesis › Research VU University Amsterdam, graduation VU University Amsterdam › Academic
Open Access
Hypoxia decreases osteogenic differentiation potential but enhances vasculogenic differentiation potential of human adipose stem cells on biphasic calcium phosphate scaffolds in fibrin gels
van Esterik, F. A. S., Hogervorst, J. M. A., Koolwijk, P. & Klein-Nulend, J., 2017, In : Journal of Stem Cells. 12, 2, p. 41-52 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Identification of HIF-2α-regulated genes that play a role in human microvascular endothelial sprouting during prolonged hypoxia in vitro
Nauta, T. D., van den Broek, M., Gibbs, S., van der Pouw-Kraan, T. C. T. M., Oudejans, C. B., van Hinsbergh, V. W. M. & Koolwijk, P., 2017, In : Angiogenesis. 20, 1, p. 39-54Research output: Contribution to journal › Article › Academic › peer-review
IGF-1 attenuates hypoxia-induced atrophy but inhibits myoglobin expression in C2C12 skeletal muscle myotubes
Peters, E. L., van der Linde, S. M., Vogel, I. S. P., Haroon, M., Offringa, C., de Wit, G. M. J., Koolwijk, P., van der Laarse, W. J. & Jaspers, R. T., 1 Sep 2017, In : International Journal of Molecular Sciences. 18, 9, 1889.Research output: Contribution to journal › Article › Academic › peer-review
The effects of hyperoxia on microvascular endothelial cell proliferation and production of vaso-active substances
Attaye, I., Smulders, Y. M., de Waard, M. C., Oudemans-van Straaten, H. M., Smit, B., Van Wijhe, M. H., Musters, R. J., Koolwijk, P. & Spoelstra-de Man, A. M. E., Apr 2017, In : Intensive Care Medicine Experimental. 5, 1, 22.Research output: Contribution to journal › Article › Academic › peer-review
2016
CD34 expression modulates tube-forming capacity and barrier properties of peripheral blood-derived endothelial colony-forming cells (ECFCs)
Tasev, D., Konijnenberg, L. S. F., Amado-Azevedo, J., van Wijhe, M. H., Koolwijk, P. & van Hinsbergh, V. W. M., Jul 2016, In : Angiogenesis. 19, 3, p. 325-338Research output: Contribution to journal › Article › Academic › peer-review
Correction: HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells
Nauta, T. D., Duyndam, M. C. A., Weijers, E. M., van Hinsbergh, V. W. M. & Koolwijk, P., 23 Sep 2016, In : PLoS ONE. 11, 9, e0163840.Research output: Contribution to journal › Article › Academic › peer-review
Extensive Characterization and Comparison of Endothelial Cells Derived from Dermis and Adipose Tissue: Potential Use in Tissue Engineering
Monsuur, H. N., Weijers, E. M., Niessen, F. B., Gefen, A., Koolwijk, P., Gibbs, S. & van den Broek, L. J., 30 Nov 2016, In : PLoS ONE. 11, 11, e0167056.Research output: Contribution to journal › Article › Academic › peer-review
Genome-Wide Identification of Epigenetic Hotspots Potentially Related to Cardiovascular Risk in Adult Women after a Complicated Pregnancy
Oudejans, C., Poutsma, A., Michel, O., Mulders, J., Visser, A., van Dijk, M., Nauta, T., Bokslag, A., Paulus, W., de Haas, A., Koolwijk, P. & de Groot, C. J. M., 12 Feb 2016, In : PLoS ONE. 11, 2, e0148313.Research output: Contribution to journal › Article › Academic › peer-review
Globular adiponectin controls insulin-mediated vasoreactivity in muscle through AMPK alpha 2
de Boer, M. P., Meijer, R. I., Richter, E. A., van Nieuw Amerongen, G., Sipkema, P., van Poelgeest, E. M., Aman, J., Kokhuis, T. J. A., Koolwijk, P., van Hinsbergh, V. W. M., Smulders, Y. M., Serne, E. H. & Eringa, E. C., Mar 2016, In : Vascular Pharmacology. 78, p. 24-35Research output: Contribution to journal › Article › Academic › peer-review
HIF-2 alpha Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells
Nauta, T. D., Duyndam, M. C. A., Weijers, E. M., van Hinsbergh, V. M. W. & Koolwijk, P., 4 Aug 2016, In : PLoS ONE. 11, 8, e0163840.Research output: Contribution to journal › Article › Academic › peer-review
HIF-2 alpha Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells (vol 11, e0160700, 2016): correction
Nauta, T. D., Duyndam, M. C. A., Weijers, E. M., van Hinsbergh, V. W. M. & Koolwijk, P., 22 Sep 2016, In : PLoS ONE. 11, 9, e0160700.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Matrix Remodeling and Osteogenic Differentiation of Human Adipose-Derived Stem Cells Increases with Higher Fibrin Matrix Stiffness
de Jong, T., Weijers, E. M., Bakker, A. D., Koolwijk, P. & Smit, T. H., Sep 2016, In : JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING. 6, 9, p. 729-738Research output: Contribution to journal › Article › Academic › peer-review
Therapeutic Potential of Human-Derived Endothelial Colony-Forming Cells in Animal Models
Tasev, D., Koolwijk, P. & van Hinsbergh, V. W. M., Oct 2016, In : Tissue engineering part b-reviews. 22, 5, p. 371-382Research output: Contribution to journal › Review article › Academic › peer-review
Vascular endothelial growth factor A (VEGF-A) decreases expression and secretion of pleiotrophin in a VEGF receptor-independent manner
Poimenidi, E., Theodoropoulou, C., Koutsioumpa, M., Skondra, L., Droggiti, E., van den Broek, M., Koolwijk, P. & Papadimitriou, E., May 2016, In : Vascular Pharmacology. 80, p. 11-19Research output: Contribution to journal › Article › Academic › peer-review
2015
Hypoxia inducible factor 1 alpha down regulates cell surface expression of alpha 1,2-fucosylated glycans in human pancreatic adenocarcinoma cells
Da Silva Aresta Belo, A. I., van Vliet, S. J., Maus, A., Laan, L. C., Nauta, T., Koolwijk, P., Tefsen, B. & van Die, I., 2015, In : FEBS Letters. 589, 18, p. 2359-2366Research output: Contribution to journal › Article › Academic › peer-review
IFN-beta affects the angiogenic potential of circulating angiogenic cells by activating calpain 1
Yildirim, C., Favre, J., Weijers, E. M., Fontijn, R. D., van Wijhe, M. H., van Vliet, S. J., Boon, R. A., Koolwijk, P., van der Pouw-Kraan, T. C. T. M. & Horrevoets, A. J., 2015, In : American Journal of Physiology. Heart and Circulatory Physiology. 309, 10, p. H1667-H1678Research output: Contribution to journal › Article › Academic › peer-review
Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting Capacity
Tasev, D. V., van Wijhe, M. H., Weijers, E. M., van Hinsbergh, V. W. M. & Koolwijk, P., 2015, In : PLoS ONE. 10, 6, e0129935.Research output: Contribution to journal › Article › Academic › peer-review
Palmitic acid increases pro-oxidant adaptor protein p66Shc expression and affects vascularization factors in angiogenic mononuclear cells: Action of resveratrol
Favre, J., Yildirim, C., Leyen, T. A., Chen, J. Y., van Genugten, R. E., van Golen, L. W., Garcia Vallejo, J. J., Musters, R. J. P., Baggen, J. M., Fontijn, R. D., van der Pouw-Kraan, T. C. T. M., Serne, E. H., Koolwijk, P., Diamant, M. & Horrevoets, A. J., 2015, In : Vascular Pharmacology. 75, p. 7-18Research output: Contribution to journal › Article › Academic › peer-review
Specific Effects of Fibrinogen and the gamma A and gamma '-Chain Fibrinogen Variants on Angiogenesis and Wound Healing
Cheung, E. Y. L., Weijers, E. M., Tuk, B., Scheffer, R., Leebeek, F. W., van Neck, J. W., Koolwijk, P. & de Maat, M. P. M., 2015, In : Tissue Engineering Part A. 21, 1-2, p. 106-114Research output: Contribution to journal › Article › Academic › peer-review
2014
Adipose tissue-derived stromal cells acquire endothelial-like features upon reprogramming with SOX18
Fontijn, R. D., Favre, J., Naaijkens, B. A., Meinster, E., Paauw, N. J., Ragghoe, S. L., Nauta, T. D., van den Broek, M. A., Weijers, E. M., Niessen, H. W. M., Koolwijk, P. & Horrevoets, A. J. G., Nov 2014, In : Stem Cell Research. 13, 3 Pt A, p. 367-378 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Expression, Regulation and Function of Human Metallothioneins in Endothelial Cells
Schulkens, I. A. E., Castricum, K. C. M., Weijers, E. M., Koolwijk, P., Griffioen, A. W. & Thijssen, V. L. J. L., 2014, In : Journal of Vascular Research. 51, 3, p. 231-238Research output: Contribution to journal › Article › Academic › peer-review
Hypoxic Signaling During Tissue Repair and Regenerative Medicine
Nauta, T., van Hinsbergh, V. W. M. & Koolwijk, P., 2014, In : International Journal of Molecular Sciences. 15, 11, p. 19791-19815Research output: Contribution to journal › Article › Academic › peer-review
NF-kappa B-inducing kinase is a key regulator of inflammation-induced and tumour-associated angiogenesis
Noort, A. R., van Zoest, K. P. M., Weijers, E. M., Koolwijk, P., Maracle, C. X., Novack, D. V., Siemerink, M. J., Schlingemann, R. O., Tak, P. P. & Tas, S. W., 2014, In : Journal of Pathology. 234, 3, p. 375-385Research output: Contribution to journal › Article › Academic › peer-review
Systemic toll-like receptor and interleukin-18 pathway activation in patients with acute ST elevation myocardial infarction
van der Pouw Kraan, C. T. M., Bernink, F. J. P., Yildirim, C., Koolwijk, P., Baggen, J. M., Timmers, L., Beek, A. M., Diamant, M., Chen, W. J. Y., van Rossum, A. C., van Royen, N., Horrevoets, A. J. G. & Appelman, J. E. A., 2014, In : Journal of Molecular and Cellular Cardiology. 67, p. 94-102Research output: Contribution to journal › Article › Academic › peer-review
2013
Computational Modeling of Angiogenesis: Towards a Multi-Scale Understanding of Cell–Cell and Cell–Matrix Interactions
Boas, S. E. M., Palm, M., Koolwijk, P. & Merks, R. M. H., 2013, Mechanical and Chemical Signaling in Angiogenesis. p. 161-183 (Mechanical and Chemical Signaling in Angiogenesis).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
Protein Arginine Methylation Is More Prone to Inhibition by S-Adenosylhomocysteine than DNA Methylation in Vascular Endothelial Cells
Esse, R., Rocha, M. S., Barroso, M., Florindo, C., Teerlink, T., Kok, R. M., Smulders, Y. M., Rivera, I., Leandro, P., Koolwijk, P., Castro, R., Blom, H. J. & de Almeida, I. T., 2013, In : PLoS ONE. 8, 2, e55483.Research output: Contribution to journal › Article › Academic › peer-review
VEGF Levels in Plasma in Relation to Platelet Activation, Glycemic Control, and Microvascular Complications in Type 1 Diabetes
Schlingemann, R. O., van Noorden, C. J. F., Diekman, M. J. M., Tiller, A., Meijers, J. C. M., Koolwijk, P. & Wiersinga, W. M., 2013, In : Diabetes Care. 36, 6, p. 1629-1634Research output: Contribution to journal › Article › Academic › peer-review
2012
Anti-angiogenic activity of the flavonoid precursor 4-hydroxychalcone
Varinska, L., van Wijhe, M., Belleri, M., Mitola, S., Perjesi, P., Presta, M., Koolwijk, P., Ivanova, L. & Mojzis, J., 2012, In : European Journal of Pharmacology. 691, 1-3, p. 125-133Research output: Contribution to journal › Article › Academic › peer-review
Endothelial insulin receptor expression in human atherosclerotic plaques: Linking micro- and macrovascular disease in diabetes?
Rensing, K. L., von der Thusen, J. H., Weijers, E. M., Bloemendaal, F. M. H., van Lammeren, G. W., Vink, A., van der Wal, A. C., van Hinsbergh, V. W. M., van der Loos, C. M., Stroes, E. S., Koolwijk, P. & Twickler, T. B., 2012, In : Atherosclerosis. 222, 1, p. 208-215Research output: Contribution to journal › Article › Academic › peer-review
Sunitinib-induced changes in circulating endothelial cell-related proteins in patients with metastatic renal cell cancer
van der Veldt, A. A. M., Vroling, L., de Haas, R. R., Koolwijk, P., van den Eertwegh, A. J. M., Haanen, J. B. A. G., van Hinsbergh, V. W. M., Broxterman, H. J. & Boven, E., 2012, In : International Journal of Cancer. 131, 4, p. E484-E493Research output: Contribution to journal › Article › Academic › peer-review
2011
51
Downloads
(Pure)
Fibrin matrices for tissue engineering. Naturally occurring fibrinogen variants alter cellular characteristics
Weijers, E. M., 2011Research output: Thesis › Research VU University Amsterdam, graduation VU University Amsterdam › Academic
File
48
Downloads
(Pure)
Progenitor Cells and Hypoxia in Angiogenesis
Verloop, R. E., 2011Research output: Thesis › Research VU University Amsterdam, graduation VU University Amsterdam › Academic
File