Projects per year
Personal profile
Research interests
My research focuses on identifying the (integrative) omics signature of depression (using DNA, methylation, gene expression, proteomics) and on finding better treatment for, and identification of, depression subtypes, mainly using data from NESDA (The Netherlands Study of Depression and Anxiety) and NTR (The Netherlands Twin Registry).
I am co PI of PERCIM (Personalized Care for Immuno-Metabolic Depression) (https://psychiatryamsterdam.nl/project/percim/) and was part of the BIOS (Biobank-based integrative omics study) consortium management (https://www.bbmri.nl/acquisition-use-analyze/bios). As NESDA, NTR and BIOS we are part of the large eQTL meta analysis: the eQTLGen Consortium (https://www.eqtlgen.org/).
I am teaching a course on human molecular genetics for the research master 'Genes in Behaviour and Health' (https://vuweb.vu.nl/nl/onderwijs/master/genes-in-behaviour-and-health).
For the publication I (co) authored see my google scholar page: https://scholar.google.nl/citations?user=cHJDM0YAAAAJ&hl=en.
And for the publications from the Consortia I participated in see:
BIOS: https://pubmed.ncbi.nlm.nih.gov/?term=BIOS+Consortium%5BCorporate+Author%5D&sort=date.
eQTLGen: https://pubmed.ncbi.nlm.nih.gov/?sort=date&term=eQTLGen+Consortium%5BCorporate+Author%5D.
See also our conditional eQTL catalog based on NESDA and NTR data:
And the Methylation and RNA-seq QTL catalogs from BIOS:
Email: ri.jansen at amsterdamumc.nl
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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PERCIM: Personalized Care for Depression: Bringing Immuno-Metabolic Depression from Bench to Bedside
Lamers, F., Jansen, R., Vreijling, S., Penninx, B., Beekman, A., Bot, M., Milaneschi, Y., Bremmer, M. & Rhebergen, D.
01/10/2019 → 30/09/2023
Project: Research
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Gene expression in major depressive disorder
Jansen, R., Penninx, B. W. J. H., Madar, V., Xia, K., Milaneschi, Y., Hottenga, J. J., Hammerschlag, A. R., Beekman, A. T. F., van der Wee, N., Smit, J. H., Brooks, A. I., Tischfield, J., Posthuma, D., Schoevers, R., Grootheest, G., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Wright, F. A., Zou, F., & 2 others, 2016, In: Molecular Psychiatry. 21, p. 339-347Research output: Contribution to journal › Article › Academic › peer-review
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Conditional eQTL analysis reveals allelic heterogeneity of gene expression
Jansen, R., Hottenga, J-J., Nivard, M. G., Abdellaoui, A., Laport, B., de Geus, E. J., Wright, F. A., Penninx, B. W. J. H. & Boomsma, D. I., 15 Apr 2017, In: Human Molecular Genetics. 26, 8, p. 1444-1451Research output: Contribution to journal › Article › Academic › peer-review
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Effects of dietary interventions on depressive symptom profiles: Results from the MooDFOOD depression prevention study
Vreijling, S. R., Penninx, B. W. J. H., Bot, M., Watkins, E., Owens, M., Kohls, E., Hegerl, U., Roca, M., Gili, M., Brouwer, I. A., Visser, M., Beekman, A. T. F., Jansen, R. & Lamers, F., 7 Nov 2022, In: Psychological Medicine. 52, 15, p. 3580-3589 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
An integrative study of five biological clocks in somatic and mental health
Jansen, R., Han, L. K. M., Verhoeven, J. E., Aberg, K. A., van den Oord, E. C. G. J., Milaneschi, Y. & Penninx, B. W. J. H., Feb 2021, In: eLife. 10, p. 1-20 20 p., e59479.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Dissection of depression heterogeneity using proteomic clusters
van Haeringen, M., Milaneschi, Y., Lamers, F., Penninx, B. W. J. H. & Jansen, R., 18 Jan 2022, (E-pub ahead of print) In: Psychological Medicine. p. 1-9 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access