Research output per year

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Personal profile

Research interests

My research interest is focussed on improving outcomes and quality of life in patients with oesophageal adenocarcinoma, and to prevent patients from developing oesophageal adenocarcinoma. For this, I run the following research lines:

1. Improving management of patients with early oesophageal adenocarcinoma.
As interventional endoscopist I am constantly trying to find less invasive, more effective and safer methods to treat patients with early stages of oesophageal adenocarcinoma and precursor lesions. This ranges from studying new endoscopic techniques or devices, to evaluating new management strategies. By improving and expanding the endoscopic arsenal and by optimizing follow-up strategies in patients treated for oesophageal adenocarcinoma, I hope we can treat more patients endoscopically, and prevent unnessecary and more invasive therapy such as surgery.


2. Identification and validation of biomarkers, for risk stratification of patients with Barrett's oesophagus.

Barrett's oesophagus is the most important risk factor for oesophageal adenocarcinoma. Patients therefore undergo regular endoscopic surveillance with biopsies. However, this is not a cost-effective approach and endoscopies can be a great burden to patients. Using a large tissue bank with samples from patients surveyed for Barrett's oesophagus who did or did not progress to cancer, I try to find biomarkers that can be used to identify patients with increased risk for cancer who may benefit from prophylactic treatment. Patients with a very low risk of progressing to cancer may be reassured and may not require further surveillance.

Education/Academic qualification

Dept. of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands

Oct 2012Aug 2017

PhD, University of Amsterdam, Amsterdam, Netherlands

1 Nov 20061 Nov 2010

Master, Faculty of Medicine, University of Utrecht, Utrecht, the Netherlands

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Research Output

Simplified versus standard regimen for focal radiofrequency ablation of dysplastic Barrett's oesophagus: a multicentre randomised controlled trial

Pouw, R. E., Künzli, H. T., Bisschops, R., Sondermeijer, C. M., Koch, A. D., Didden, P., Gotink, A. W., Schoon, E. J., Curvers, W. L., Bergman, J. J. G. H. M. & Weusten, B. L. A. M., Aug 2018, In : The Lancet Gastroenterology and Hepatology. 3, 8, p. 566-574 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Long-term follow-up results of stepwise radical endoscopic resection for Barrett's esophagus with early neoplasia

Belghazi, K., van Vilsteren, F. G. I., Weusten, B. L. A. M., Meijer, S. L., Bergman, J. J. G. H. M. & Pouw, R. E., Jan 2018, In : Gastrointestinal Endoscopy. 87, 1, p. 77-84 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

A prospective multicenter study using a new multiband mucosectomy device for endoscopic resection of early neoplasia in Barrett's esophagus

Pouw, R. E., Beyna, T., Belghazi, K., Koch, A. D., Schoon, E. J., Haidry, R., Weusten, B. L., Bisschops, R., Shaheen, N. J., Wallace, M. B., Marcon, N., Heise-Ginsburg, R., Gotink, A. W., Wang, K. K., Leggett, C. L., Ortiz-Fernández-Sordo, J., Ragunath, K., DiPietro, M., Pech, O., Neuhaus, H. & 1 others, Bergman, J. J., Oct 2018, In : Gastrointestinal Endoscopy. 88, 4, p. 647-654 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Risk factors for serious adverse events associated with multiband mucosectomy in Barrett's esophagus: an international multicenter analysis of 3827 endoscopic resection procedures

Belghazi, K., Marcon, N., Teshima, C., Wang, K. K., Milano, R. V., Mostafavi, N., Wallace, M. B., Kandel, P., Mejía Pérez, L. K., Bourke, M. J., Bahin, F., Everson, M. A., Haidry, R., Ginsberg, G. G., Ma, G., Koch, A. D., Ragunath, K., Ortiz-Fernandez-Sordo, J., di Pietro, M., Seewald, S. & 5 others, Weusten, B. L., Schoon, E. J., Bisschops, R., Bergman, J. J. & Pouw, R. E., 30 Mar 2020, In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticleAcademicpeer-review

The Amsterdam ReBus progressor cohort: identification of 165 Barrett's surveillance patients who progressed to early neoplasia and 723 nonprogressor patients

Duits, L. C., Klaver, E., Bureo Gonzalez, A., Boerwinkel, D. F., Ten Kate, F. J. W., Offerhaus, G. J. A., Meijer, S. L., Visser, M., Seldenrijk, C. A., Krishnadath, K. K., Schoon, E. J., Weusten, B. L. A. M., Mallant-Hent, R. C., Pouw, R. E. & Bergman, J. J. G. H. M., 13 Nov 2019, In : Diseases of the Esophagus. 32, 9

Research output: Contribution to journalArticleAcademicpeer-review


  • 3 Membership of board
  • 1 Membership of guidelines

United European Gastroenterology Journal (External organisation)

Roos Pouw (Member)
1 Jan 20201 Jan 2025

Activity: MembershipMembership of board

European Society for Gastroenterologic Endoscopy (External organisation)

Roos Pouw (Chair)
29 Jun 2020

Activity: MembershipMembership of guidelines

Best Practice & Research; Clinical Gastroenterology (External organisation)

Roos Pouw (Member)
1 Jun 2019 → …

Activity: MembershipMembership of board

Current Treatment Options in Gastroenterology (External organisation)

Roos Pouw (Member)
1 Apr 2016 → …

Activity: MembershipMembership of board


AMC PhD Thesis Award 2011

Roos Pouw (Recipient), 2011

Prize: Other distinction

Janssen Gastrointestinal Research Award

Roos Pouw (Recipient), 2011

Prize: Other distinction


Roos Pouw (Recipient), 1 Jan 2020

Prize: Other distinction