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Research Output 2008 2019

  • 22 Article
  • 1 Research VU University Amsterdam, graduation VU University Amsterdam
2019

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms

The EAGLE-ADHD Consortium, 2019, In : Behavior Genetics.

Research output: Contribution to journalArticleAcademicpeer-review

2018

SICT: automated detection and supervised inspection of fast Ca2+ transients

Mancini, R., van der Bijl, T., Bourgeois-Jaarsma, Q., Lasabuda, R. & Groffen, A. J., 2018, In : Scientific Reports. 8, 1, 15523.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Transcription Factor 2I Regulates Neuronal Development via TRPC3 in 7q11.23 Disorder Models

Deurloo, M. H. S., Turlova, E., Chen, W-L., Lin, Y. W., Tam, E., Tassew, N. G., Wu, M., Huang, Y-C., Crawley, J. N., Monnier, P. P., Groffen, A. J. A., Sun, H-S., Osborne, L. R. & Feng, Z-P., 2018, In : Molecular Neurobiology.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

δ-Catenin (CTNND2) missense mutation in familial cortical myoclonic tremor and epilepsy

Van Rootselaar, A. F., Groffen, A. J., Vries, B. D., Callenbach, P. M. C., Santen, G. W. E., Koelewijn, S., Vijfhuizen, L. S., Buijink, A., Tijssen, M. A. J. & Van Den Maagdenberg, A. M. J. M., 1 Dec 2017, In : Neurology. 89, 23, p. 2341-2350 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2015

Direct quantitative detection of Doc2b-induced hemifusion in optically trapped membranes

Brouwer, I., Giniatullina, A., Laurens, N., van Weering, J. R. T., Bald, D., Wuite, G. J. L. & Groffen, A. J. A., 2015, In : Nature Communications. 6, p. 8387 8387.

Research output: Contribution to journalArticleAcademicpeer-review

Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences

Giniatullina, A., Maroteaux, G. P., Geerts, C. J., Koopmans, B., Loos, M., Klaassen, R. V., Chen, N., van der Schors, R. C., van Nierop, P., Li, K. W., de Jong, A. P. H., Altrock, W. D., Cornelisse, L. N., Toonen, R. F. G., van der Sluis, S., Sullivan, P. F., Stiedl, O., Posthuma, D., Smit, A. B., Groffen, A. J. A. & 1 othersVerhage, M., 2015, In : Neuroscience. 300, p. 518-538

Research output: Contribution to journalArticleAcademicpeer-review

Identification of a Dutch founder mutation in MUSK causing fetal akinesia deformation sequence.

Tan-Sindhunata, M. B., Matthijssen, I. B., Smit, M., Baas, F., de Vries, J. I. P., van der Voorn, J. P., Kluijt, I., Hagen, M. A., Blom, E. W., Sistermans, E. A., Heijboer-Meijers, J. E., Waisfisz, Q., Weiss, M. M. & Groffen, A. J. A., 2015, In : European Journal of Human Genetics. 23, 9, p. 1151-1157

Research output: Contribution to journalArticleAcademicpeer-review

Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates.

Geerts, C. J., Plomp, J. J., Koopmans, B., Loos, M., van der Pijl, EM., van der Valk, M. A., Verhage, M. & Groffen, A. J. A., 2015, In : Brain Structure and Function. 220, 4, p. 1971-1982

Research output: Contribution to journalArticleAcademicpeer-review

Two male adults with pathogenic AUTS2 variants, including a two-base pair deletion, further delineate the AUTS2 syndrome

Beunders, G., de Munnik, S. A., van der Aa, N. E., Ceulemans, B., Voorhoeve, E., Groffen, A. J. A., Nillesen, W. M., Meijers-Heijboer, E. J., Kooy, F. R., Yntema, H. G. & Sistermans, E. A., 2015, In : European Journal of Human Genetics. 23, 6, p. 803-807

Research output: Contribution to journalArticleAcademicpeer-review

2014

DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake

Li, J., Cantley, J., Burchfield, J. G., Meoli, C. C., Stöckli, J., Whitworth, P. T., Pant, H., Chaudhuri, R., Groffen, A. J. A., Verhage, M. & James, D. E., 2014, In : Diabetologia. 57, 10, p. 2173-2182

Research output: Contribution to journalArticleAcademicpeer-review

Tomosyn Interacts with the SUMO E3 Ligase PIAS gamma

Geerts, C. J., Jacobsen, L., van de Bospoort, R., Verhage, M. & Groffen, A. J. A., 2014, In : PLoS ONE. 9, 3, p. e91697 e91697.

Research output: Contribution to journalArticleAcademicpeer-review

2013

Doc2b synchronizes secretion from chromaffin cells by stimulating fast and inhibiting sustained release

Pinheiro, P. S., de Wit, H., Walter, A. M., Groffen, A. J. A., Verhage, M. & Sørensen, J. B., 2013, In : Journal of Neuroscience. 33, 42, p. 16459-16470

Research output: Contribution to journalArticleAcademicpeer-review

Exonic Deletions in AUTS2 Cause a Syndromic Form of Intellectual Disability and Suggest a Critical Role for the C Terminus

Beunders, G., Voorhoeve, E., Golzio, C., Pardo, L. M., Rosenfeld, J. A., Talkowski, M. E., Simonic, I., Lionel, A. C., Vergult, S., Pyatt, R. E., van de Kamp, J. M., Nieuwint, A. W. M., Weiss, M. M., Rizzu, P., Verwer, L. E. N. I., van Spaendonk, R. M. L., Shen, Y. P., Wu, B. L., Yu, T. T., Yu, Y. G. & 43 othersChiang, C., Gusella, J. F., Lindgren, A. M., Morton, C. C., van Binsbergen, E., Bulk, S., van Rossem, E., Vanakker, O., Armstrong, R., Park, S. M., Greenhalgh, L., Maye, U., Neill, N. J., Abbott, K. M., Sell, S., Ladda, R., Farber, D. M., Bader, P. I., Cushing, T., Drautz, J. M., Konczal, L., Nash, P., de Los Reyes, E., Carter, M. T., Hopkins, E., Marshall, C. R., Osborne, L. R., Gripp, K. W., Thrush, D. L., Hashimoto, S., Gastier-Foster, J. M., Astbury, C., Ylstra, B., Meijers-Heijboer, E. J., Posthuma, D., Menten, B., Mortier, G., Scherer, S. W., Eichler, E. E., Girirajan, S., Katsanis, N., Groffen, A. J. A. & Sistermans, E. A., 2013, In : American journal of human genetics. 92, 2, p. 210-220

Research output: Contribution to journalArticleAcademicpeer-review

Genetic and phenotypic heterogeneity in sporadic and familial forms of paroxysmal dyskinesia

Groffen, A. J. A., Klapwijk, T., van Rootselaar, A. F., Groen, J. L. & Tijssen, M. A., 2013, In : Journal of Neurology. 260, 1, p. 93-99

Research output: Contribution to journalArticleAcademicpeer-review

TRIM3 Regulates the Motility of the Kinesin Motor Protein KIF21B

Labonté, D., Thies, E., Pechmann, Y., Groffen, A. J. A., Verhage, M., Smit, A. B., van Kesteren, R. E. & Kneussel, M., 2013, In : PLoS ONE. 8, 9, p. e75603 e75603.

Research output: Contribution to journalArticleAcademicpeer-review

2012

Doc2b Is a Key Effector of Insulin Secretion and Skeletal Muscle Insulin Sensitivity

Ramalingam, L., Oh, E., Yoder, S. M., Brozinick, J. T., Kalwat, M. A., Groffen, A. J. A., Verhage, M. & Thurmond, D. C., 2012, In : Diabetes. 61, 10, p. 2424-2432

Research output: Contribution to journalArticleAcademicpeer-review

Paroxysmal kinesigenic dyskinesia: Cortical or non-cortical origin

van Strien, T. W., van Rootselaar, A. F., Hilgevoord, A. A. J., Linssen, W. H. J. P., Groffen, A. J. A. & Tijssen, M. A. J., 2012, In : Parkinsonism and Related Disorders. 18, 5, p. 645-648

Research output: Contribution to journalArticleAcademicpeer-review

2011

Deletion of Munc18-1 in 5-HT Neurons Results in Rapid Degeneration of the 5-HT System and Early Postnatal Lethality

Dudok, J. J., Groffen, A. J. A., Toonen, R. F. G. & Verhage, M., 2011, In : PLoS ONE. 6, 11, e28137.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Multiple Ca(2+) sensors in secretion: teammates, competitors or autocrats?

Walter, A. M., Groffen, A. J. A., Sorensen, J. B. & Verhage, M., 2011, In : Trends in Neurosciences. 34, 9, p. 487-497

Research output: Contribution to journalArticleAcademicpeer-review

2010

Cellular characterization of the outgrowth and connectivity of the brain serotonin system

Dudok, J. J., 2010, 165 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

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Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release

Groffen, A. J. A., Martens, S., Diez Arazola, R., Cornelisse, L. N., Lozovaya, N., de Jong, A. P. H., Goriounova, N. A., Habets, R. L., Takai, Y., Borst, J. G., Brose, N., McMahon, H. T. & Verhage, M., 2010, In : Science. 327, 5973, p. 1614-1618 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

2009

Chronic activation of the 5-HT(2) receptor reduces 5-HT neurite density as studied in organotypic slice cultures

Dudok, J. J., Groffen, A. J. A., Witter, M. P., Voorn, P. & Verhage, M., 2009, In : Brain Research. 1302, p. 1-9 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2008

DOC2B acts as a calcium switch and enhances vesicle fusion

Friedrich, R., Groffen, A. J. A., Connell, E., van Weering, J. R. T., Gotman, O., Henis, Y. I., Davletov, B. & Ashery, U., 2008, In : Journal of Neuroscience. 28, p. 6794-6806 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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