Research output per year
Research output per year
Personal profile
Research interests
Our group is interested in deciphering the molecular response mechanisms to clinical schedules of fractionated radiotherapy. The overarching goal is to understand how tumor cells and the tumor micro-environment respond to different schedules of fractionated radiotherapy in order to optimize dose-scheduling of combination therapies.
Over the last decade, we have used different approaches to determine the role of the tumor microenvironment in the response to radiotherapy and to monitor the cellular response(s) of the tumor microenvironment to radiotherapy. This includes studies in cultured cell in vitro, in tumor models in vivo as well as in tumor tissues derived from cancer patients.
Specialisation
Angiogenesis
Radiobiology
Molecular Cell Biology
Glycobiology
External positions
Postdoc, Maastricht UMC
2002 → 2009PhD student, Maastricht UMC
1997 → 2002Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Research output
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Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro
Dickhout, A., Tullemans, B. M. E., Heemskerk, J. W. M., Thijssen, V. L. J. L., Kuijpers, M. J. E. & Koenen, R. R., 1 Jan 2021, In: PLoS ONE. 16, 1 January, e0244736.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation
Goedegebuure, R. S. A., Kleibeuker, E. A., Buffa, F. M., Castricum, K. C. M., Haider, S., Schulkens, I. A., ten Kroode, L., van den Berg, J., Jacobs, M. A. J. M., van Berkel, A-M., van Grieken, N. C. T., Derks, S., Slotman, B. J., Verheul, H. M. W., Harris, A. L. & Thijssen, V. L., 1 Dec 2021, In: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 40, 1, 161.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Molecular profiles of response to neoadjuvant chemoradiotherapy in oesophageal cancers to develop personalized treatment strategies
de Klerk, L. K., Goedegebuure, R. S. A., van Grieken, N. C. T., van Sandick, J. W., Cats, A., Stiekema, J., van der Kaaij, R. T., Farina Sarasqueta, A., van Engeland, M., Jacobs, M. A. J. M., van Wanrooij, R. L. J., van der Peet, D. L., Thorner, A. R., Verheul, H. M. W., Thijssen, V. L. J. L., Bass, A. J. & Derks, S., Apr 2021, In: Molecular oncology. 15, 4, p. 901-914 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Combining Radiation Therapy With Interferons: Back to the Future
Goedegebuure, R. S. A., Vonk, C., Kooij, L. P., Derks, S. & Thijssen, V. L. J. L., 1 Sep 2020, In: International Journal of Radiation Oncology Biology Physics. 108, 1, p. 56-69 14 p.Research output: Contribution to journal › Review article › Academic › peer-review
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Development of transient radioresistance during fractionated irradiation in vitro
van den Berg, J., Castricum, K. C. M., Meel, M. H., Goedegebuure, R. S. A., Lagerwaard, F. J., Slotman, B. J., Hulleman, E. & Thijssen, V. L. J. L., Jul 2020, In: Radiotherapy and Oncology. 148, p. 107-114 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Activities
- 4 Examination
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Tumor-associated glycan structures: friend or foe in immunity to cancer?
Victor Thijssen (Examiner)
2 Jul 2019Activity: Examination
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Platelets and Platelet Extracellular Vesicles as Messengers in Vascular Inflammation
Victor Thijssen (Examiner)
9 Nov 2017Activity: Examination
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The IL-17 and Th17 cell immune response in cervical cancer
Victor Thijssen (Examiner)
8 Sep 2015Activity: Examination
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