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Research Output 2008 2019

Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets?

Ortega Ugalde, S., Boot, M., Commandeur, J. N. M., Jennings, P., Bitter, W. & Vos, J. C., 2019, In : Applied Microbiology and Biotechnology. 103, 9, p. 3597-3614

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator

Abdallah, A. M., Weerdenburg, E. M., Guan, Q., Ummels, R., Borggreve, S., Adroub, S. A., Malas, T. B., Naeem, R., Zhang, H., Otto, T. D., Bitter, W. & Pain, A., 2019, In : PLoS ONE. 14, 1, e0211003.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Protease domain and transmembrane domain of the type VII secretion mycosin protease determine system-specific functioning in mycobacteria

van Winden, V. J. C., Damen, M. P. M., Ummels, R., Bitter, W. & Houben, E. N. G., 2019, In : Journal of Biological Chemistry. 294, 13, p. 4806-4814

Research output: Contribution to journalArticleAcademicpeer-review

Accelerating early antituberculosis drug discovery by creating mycobacterial indicator strains that predict mode of action

Boot, M., Commandeur, S., Subudhi, A. K., Bahira, M., Smith, T. C., Abdallah, A. M., van Gemert, M., Lelièvre, J., Ballell, L., Aldridge, B. B., Pain, A., Speer, A. & Bitter, W., 2018, In : Antimicrobial Agents and Chemotherapy. 62, 7, e00083-18.

Research output: Contribution to journalArticleAcademicpeer-review

Engineering a self-sufficient Mycobacterium tuberculosis CYP130 by gene fusion with the reductase-domain of CYP102A1 from Bacillus megaterium

Ortega Ugalde, S., Luirink, R. A., Geerke, D. P., Vermeulen, N. P. E., Bitter, W. & Commandeur, J. N. M., 2018, In : Journal of Inorganic Biochemistry. 180, p. 47-53

Research output: Contribution to journalArticleAcademicpeer-review