20132019
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Research Output 2013 2019

  • 31 Article
  • 1 Review article
  • 1 Research VU University Amsterdam, graduation VU University Amsterdam
2019

A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics

Milaneschi, Y., Peyrot, W. J., Nivard, M. G., Mbarek, H., Boomsma, D. I. & W.J.H. Penninx, B., 1 Dec 2019, In : Translational Psychiatry. 9, 1, 219.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T. K., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., Lawrie, S. M., Deary, I. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M. & 51 othersAndlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Bigdeli, T. B., Beekman, A. T. F., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Jansen, R., Middeldorp, C. M., Milaneschi, Y., Peyrot, W. J., Posthuma, D., Smit, J. H., de Geus, E. J. C., Penninx, B. W. J. H., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 23andMe Research team, Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D. & Sullivan, P. F., 1 Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Glanville, K. P., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., Breen, G., Air, T. M., Andlauer, T. F. M., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J. & 33 othersde Geus, E. J. C., Grabe, H. J., Hamilton, S. P., Jones, I., Jones, L. A., Knowles, J. A., Kutalik, Z., Levinson, D. F., Lewis, G., Lind, P. A., Lucae, S., Magnusson, P. K., McGuffin, P., McIntosh, A. M., Milaneschi, Y., Mors, O., Mostafavi, S., Müller-Myhsok, B., Pedersen, N. L., Penninx, B. W. J. H., Potash, J. B., Preisig, M., Ripke, S., Beekman, A. T. F., Jansen, R., Middeldorp, C. M., Peyrot, W. J., Posthuma, D., Schoevers, R., Smit, J. H., de Geus, E. J. C., Weissman, M. M. & O'Reilly, P. F., 1 Jan 2019, In : Biological Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic correlations of polygenic disease traits: from theory to practice

van Rheenen, W., Peyrot, W. J., Schork, A. J., Lee, S. H. & Wray, N. R., 2019, In : Nature Reviews Genetics.

Research output: Contribution to journalReview articleAcademicpeer-review

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L., Caplin, A. H. & 46 othersChen, C-Y., Eibich, P., Fontanillas, P., Gonzalez, J. R., Joshi, P. K., Karhunen, V., Kleinman, A., Levin, R. Z., Lill, C. M., Meddens, G. A., Muntané, G., Sanchez-Roige, S., Rooij, F. J. V., Taskesen, E., Wu, Y., Jansen, R., Penninx, B., Peyrot, W. J., Evans, D. M., Milaneschi, Y., Penninx, B., Posthuma, D., Posthuma, D., Jansen, R., Penninx, B., Peyrot, W. J., Evans, D. M., Milaneschi, Y., Penninx, B., Posthuma, D., 23and Me Research Team, Schunk, D., Stein, M. B., Svento, R., Tiemeier, H., Timmers, P. R. H. J., Turley, P., Ursano, R. J., Wagner, G. G., Wilson, J. F., Gratten, J., Lee, J. J., Cesarini, D., Benjamin, D. J., Koellinger, P. D. & Beauchamp, J. P., 1 Feb 2019, In : Nature Genetics. 51, p. 245-257 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of common genetic risk variants for autism spectrum disorder

Grove, J., Ripke, S., Als, T. D., Mattheisen, M., Walters, R. K., Won, H., Pallesen, J., Agerbo, E., Andreassen, O. A., Anney, R., Awashti, S., Belliveau, R., Bettella, F., Buxbaum, J. D., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Cerrato, F., Chambert, K., Christensen, J. H., Churchhouse, C. & 41 othersDellenvall, K., Demontis, D., de Rubeis, S., Devlin, B., Djurovic, S., Dumont, A. L., Goldstein, J. I., Hansen, C. S., Hauberg, M. E., Hollegaard, M. V., Beekman, A. T. F., Jansen, R., Middeldorp, C. M., Milaneschi, Y., Peyrot, W. J., Posthuma, D., Schoevers, R., Smit, J. H., de Geus, E. J. C., Penninx, B. W. J. H., Beekman, A. T. F., Jansen, R., Middeldorp, C. M., Milaneschi, Y., Peyrot, W. J., Posthuma, D., Schoevers, R., Smit, J. H., de Geus, E. J. C., Penninx, B. W. J. H., Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, Stefansson, K., Geschwind, D. H., Nordentoft, M., Hougaard, D. M., Werge, T., Mors, O., Bo Mortensen, P., Neale, B. M., Daly, M. J. & Børglum, A. D., 1 Mar 2019, In : Nature Genetics. 51

Research output: Contribution to journalArticleAcademicpeer-review

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Czamara, D., Eraslan, G. K., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O’Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C., Jones, M. J. & 34 othersLin, D. T. S., MacIsaac, J. L., Kobor, M. S., Koen, N., Zar, H. J., Koenen, K. C., Dalvie, S., Stein, D. J., Kondofersky, I., Müller, N. S., Beekman, A. T. F., Jansen, R., Middeldorp, C. M., Milaneschi, Y., Peyrot, W. J., Posthuma, D., Schoevers, R., Smit, J. H., de Geus, E. J. C., Penninx, B. W. J. H., Beekman, A. T. F., Jansen, R., Middeldorp, C. M., Milaneschi, Y., Peyrot, W. J., Posthuma, D., Schoevers, R., Smit, J. H., de Geus, E. J. C., Penninx, B. W. J. H., Theis, F. J., Räikkönen, K., Binder, E. B. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Dec 2019, In : Nature Communications. 10, 1, 2548.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2019, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180

Research output: Contribution to journalArticleAcademicpeer-review

2018

Collaborative meta-Analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olié, E., Villafuerte, S., Air, T. M. & 73 othersAraya, R., Bowes, L., Burns, R., Byrne, E. M., Coffey, C., Coventry, W. L., Gawronski, K. A. B., Glei, D., Hatzimanolis, A., Hottenga, J. J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J. R., Lajnef, M., Little, K., Zu Schwabedissen, H. M., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W. J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., Van Der Auwera, S., Wainwright, N., Wang, J. C., Willemsen, G., Anderson, I. M., Arolt, V., Aslund, C., Bagdy, G., Baune, B. T., Bellivier, F., Boomsma, D. I., Courtet, P., Dannlowski, U., De Geus, E. J. C., Deakin, J. F. W., Easteal, S., Eley, T., Fergusson, D. M., Goate, A. M., Gonda, X., Grabe, H. J., Holzman, C., Johnson, E. O., Kennedy, M., Laucht, M., Martin, N. G., Munafò, M. R., Nilsson, K. W., Oldehinkel, A. J., Olsson, C. A., Ormel, J., Otte, C., Patton, G. C., Penninx, B. W. J. H., Ritchie, K., Sarchiapone, M., Scheid, J. M., Serretti, A., Smit, J. H., Stefanis, N. C., Surtees, P. G., Völzke, H., Weinstein, M., Whooley, M., Nurnberger, J. I., Breslau, N. & Bierut, L. J., 1 Jan 2018, In : Molecular Psychiatry. 23, 1, p. 133-142 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. V., Madden, P. A. F., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A., Wray, N. R., Ripke, S. & 28 othersMattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Penninx, B. W. J. H., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Jansen, R., Middeldorp, C. M., Milaneschi, Y., Posthuma, D., Schoevers, R., Smit, J. H., de Geus, E. J. C. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 15 Jul 2018, In : Biological Psychiatry. 84, 2, p. 138-147 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

23andMe Research team, 2018, In : Nature Genetics. 50, 8, p. 1112-1121

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N. & 196 othersCastelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Giusti-Rodríguez, P., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hannon, E., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Hu, M., Hyde, C. L., Ising, M., Jansen, R., Jin, F., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lane, J. M., Li, Y., Li, Y., Lind, P. A., Liu, X., Lu, L., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, DI., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mill, J., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Purcell, S. M., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Saeed Mirza, S., Saxena, R., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. B. C., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Stockmeier, C. A., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Tian, C., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van Der Auwera, S., Van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., De Geus, E. C. J., Depaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Hinds, D. A., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. F. A., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O'Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Winslow, A. R., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D. & Sullivan, P. F., 1 May 2018, In : Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD

Van der Auwera, S., Peyrot, W. J., Milaneschi, Y., Hertel, J., Baune, B., Breen, G., Byrne, E., Dunn, E. C., Fisher, H., Homuth, G., Levinson, D., Lewis, C., Mills, N., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rietschel, M., Ripke, S., Sullivan, P. & 7 othersTeumer, A., Völzke, H., Boomsma, D. I., Wray, N. R., Penninx, B., Grabe, H. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2018, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 177, 1, p. 40-49 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland, 2018, In : PLoS ONE. 13, 12, e0209160.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., Lewis, C., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rivera, M., Rietschel, M., Streit, F., Strohmaier, J., Teumer, A. & 5 othersVan der Auwera, S., Wray, N. R., Boomsma, D. I., Penninx, B. W. J. H. & CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Dec 2017, In : JAMA Psychiatry. 74, 12, p. 1214-1225 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genetic effects influencing risk for major depressive disorder in China and Europe

Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S. A., Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschøn, H. N., Byrne, E. M., Cichon, S., Clarke, T. K., Couvy-Duchesne, B., Craddock, N., De Geus, E. J. C., Degenhardt, F. & 31 othersDunn, E. C., Edwards, A. C., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D., Grabe, H. J., Hamilton, S. P., Hardiman, O., Hayward, C., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Hottenga, J. J., Ising, M., Jansen, R., Kloiber, S., Knowles, J. A., Lang, M., Li, Q. S., Milaneschi, Y., Penninx, B. W. J. H., Peyrot, W. J., Schoevers, R., Smit, J. H., Van Grootheest, G. & on behalf of the CONVERGE consortium and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 2017, In : Translational Psychiatry. 7, 3, e1074.

Research output: Contribution to journalArticleAcademicpeer-review

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., Van Vliet-Ostaptchouk, J. V., Snieder, H., Medland, S. E., Martin, N. G., Magnusson, P. K. E., Iacono, W. G., McGue, M., North, K. E., Yang, J. & Visscher, P. M., 10 Jan 2017, In : Nature Human Behaviour. 1, 1, 0016.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults

Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 33 othersHayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Huppertz, C., Peyrot, W. J., van Grootheest, G., Milaneschi, Y., Penninx, B. W. J. H., CHARGE Consortium, EPIC-InterAct Consortium & PAGE Consortium, 1 Apr 2017, In : PLoS Genetics. 13, 4, e1006528.

Research output: Contribution to journalArticleAcademicpeer-review

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

Rietschel, L., Streit, F., Zhu, G., McAloney, K., Frank, J., Couvy-Duchesne, B., Witt, S. H., Binz, T. M., (CORNET) Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC), 1 Dec 2017, In : Scientific Reports. 7, 1, 15351.

Research output: Contribution to journalArticleAcademicpeer-review

The complex link between genetic effects and environment in depression

Peyrot, W., 2017, 281 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

Open Access

Using Clinical Characteristics to Identify Which Patients With Major Depressive Disorder Have a Higher Genetic Load for Three Psychiatric Disorders

Verduijn, J., Milaneschi, Y., Peyrot, W. J., Hottenga, J. J., Abdellaoui, A., de Geus, E. J. C., Smit, J. H., Breen, G., Lewis, C. M., Boomsma, D. I., Beekman, A. T. F. & Penninx, B. W. J. H., 15 Feb 2017, In : Biological Psychiatry. 81, 4, p. 316-324 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

Disease and Polygenic Architecture: Avoid Trio Design and Appropriately Account for Unscreened Control Subjects for Common Disease

Peyrot, W. J., Boomsma, D. I., Penninx, B. W. J. H. & Wray, N. R., 4 Feb 2016, In : American journal of human genetics. 98, 2, p. 382-391

Research output: Contribution to journalArticleAcademicpeer-review

Exploring Boundaries for the Genetic Consequences of Assortative Mating for Psychiatric Traits

Peyrot, W. J., Robinson, M. R., Penninx, B. W. J. H. & Wray, N. R., Nov 2016, In : JAMA Psychiatry. 73, 11, p. 1189-1195

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association study identifies 74 loci associated with educational attainment

Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G-B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., de Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G. & 235 othersBrandsma, J. H., Concas, M. P., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., van der Lee, S. J., de Leeuw, C., Lind, P. A., Lindgren, K-O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., van der Most, P. J., Oldmeadow, C., Payton, A., Pervjakova, N., Peyrot, W. J., Qian, Y., Raitakari, O., Rueedi, R., Salvi, E., Schmidt, B., Schraut, K. E., Shi, J., Smith, A. V., Poot, R. A., St Pourcain, B., Teumer, A., Thorleifsson, G., Verweij, N., Vuckovic, D., Wellmann, J., Westra, H-J., Yang, J., Zhao, W., Zhu, Z., Alizadeh, B. Z., Amin, N., Bakshi, A., Baumeister, S. E., Biino, G., Bonnelykke, K., Boyle, P. A., Campbell, H., Cappuccio, F. P., Davies, G., De Neve, J-E., Deloukas, P., Demuth, I., Ding, J., Eibich, P., Eisele, L., Eklund, N., Evans, D. M., Faul, J. D., Feitosa, M. F., Forstner, A. J., Gandin, I., Gunnarsson, B., Halldorsson, B. V., Harris, T. B., Heath, A. C., Hocking, L. J., Holliday, E. G., Homuth, G., Horan, M. A., Hottenga, J-J., de Jager, P. L., Joshi, P. K., Jugessur, A., Kaakinen, M. A., Kahonen, M., Kanoni, S., Keltigangas-Jarvinen, L., Kiemeney, L. A. L. M., Kolcic, I., Koskinen, S., Kraja, A. T., Kroh, M., Kutalik, Z., Latvala, A., Launer, L. J., Lebreton, M. P., Levinson, D. F., Lichtenstein, P., Lichtner, P., Liewald, D. C. M., Loukola, A., Madden, P. A., Magi, R., Maki-Opas, T., Marioni, R. E., Marques-Vidal, P., Meddens, G. A., McMahon, G., Meisinger, C., Meitinger, T., Milaneschi, Y., Milani, L., Montgomery, G. W., Myhre, R., Nelson, C. P., Nyholt, D. R., Ollier, W. E. R., Palotie, A., Paternoster, L., Pedersen, N. L., Petrovic, K. E., Porteous, D. J., Raikkonen, K., Ring, S. M., Robino, A., Rostapshova, O., Rudan, I., Rustichini, A., Salomaa, V., Sanders, A. R., Sarin, A-P., Schmidt, H., Scott, R. J., Smith, B. H., Smith, J. A., Staessen, J. A., Steinhagen-Thiessen, E., Strauch, K., Terracciano, A., Tobin, M. D., Ulivi, S., Vaccargiu, S., Quaye, L., van Rooij, F. J. A., Venturini, C., Vinkhuyzen, A. A. E., Volker, U., Volzke, H., Vonk, J. M., Vozzi, D., Waage, J., Ware, E. B., Willemsen, G., Attia, J. R., Bennett, D. A., Berger, K., Bertram, L., Bisgaard, H., Boomsma, D. I., Borecki, I. B., Bultmann, U., Chabris, C. F., Cucca, F., Cusi, D., Deary, I. J., Dedoussis, G. V., van Duijn, C. M., Eriksson, J. G., Franke, B., Franke, L., Gasparini, P., Gejman, P. V., Gieger, C., Grabe, H-J., Gratten, J., Groenen, P. J. F., Gudnason, V., van der Harst, P., Hayward, C., Hinds, D. A., Hoffmann, W., Hyppnen, E., Iacono, W. G., Jacobsson, B., Jarvelin, M-R., Jockel, K-H., Kaprio, J., Kardia, S. L. R., Lehtimaki, T., Lehrer, S. F., Magnusson, P. K. E., Martin, N. G., McGue, M., Metspalu, A., Pendleton, N., Penninx, B. W. J. H., Perola, M., Pirastu, N., Pirastu, M., Polasek, O., Posthuma, D., Power, C., Province, M. A., Samani, N. J., Schlessinger, D., Schmidt, R., Sorensen, T. I. A., Spector, T. D., Stefansson, K., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tiemeier, H., Tung, J. Y., Uitterlinden, A. G., Vitart, V., Vollenweider, P., Weir, D. R., Wilson, J. F., Wright, A. F., Conley, D. C., Krueger, R. F., Smith, G. D., Hofman, A., Laibson, D. I., Medland, S. E., Meyer, M. N., Yang, J., Johannesson, M., Visscher, P. M., Esko, T., Koellinger, P. D., Cesarini, D. & Benjamin, D. J., 26 May 2016, In : Nature. 533, 7604, p. 539-+

Research output: Contribution to journalArticleAcademicpeer-review

Polygenic dissection of major depression clinical heterogeneity

Milaneschi, Y., Lamers, F., Peyrot, W. J., Abdellaoui, A., Willemsen, G., Hottenga, J-J., Jansen, R., Mbarek, H., Dehghan, A., Lu, C., Boomsma, D. I. & Penninx, B. W. J. H., Apr 2016, In : Molecular Psychiatry. 21, 4, p. 516-522

Research output: Contribution to journalArticleAcademicpeer-review

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations

Gratten, J., Wray, N. R., Peyrot, W. J., McGrath, J. J., Visscher, P. M. & Goddard, M. E., Jul 2016, In : Nature Genetics. 48, 7, p. 718-724

Research output: Contribution to journalArticleAcademicpeer-review

2015

Glucocorticoid and mineralocorticoid receptor polymorphisms and recurrence of major depressive disorder

Hardeveld, F., Spijker, J., Peyrot, W., de Graaf, R., Hendriks, S. M., Nolen, W. A., Penninx, B. W. & Beekman, A. T., 2015, In : Psychoneuroendocrinology. 55, p. 154-163

Research output: Contribution to journalArticleAcademicpeer-review

The association between lower educational attainment and depression owing to shared genetic effects? Results in ~ 25 000 subjects

Peyrot, W., Lee, S. H., Milaneschi, Y., Abdellaoui, A., Byrne, E. M., Esko, T., de Geus, E. J. C., Hemani, G., Hottenga, J. J., Kloiber, S., Levinson, D. F., Lucae, S., Martin, N. G., Medland, S. E., Metspalu, A., Milani, L., Noethen, M. M., Potash, J. B., Rietschel, M., Rietveld, C. A. & 9 othersRipke, S., Shi, J., Willemsen, G., Zhu, Z., Boomsma, D. I., Wray, N. R., Posthuma, D., Middeldorp, C. M. & Penninx, B. W. J. H., 2015, In : Molecular Psychiatry. 20, 6, p. 735-743 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2014

Effect of polygenic risk scores on depression in childhood trauma

Peyrot, W. J., Milaneschi, Y., Abdellaoui, A., Sullivan, P. F., Hottenga, J. J., Boomsma, D. I. & Penninx, B. W. J. H., 2014, In : British Journal of Psychiatry. 205, 2, p. 113-119

Research output: Contribution to journalArticleAcademicpeer-review

Sex differences in the human peripheral blood transcriptome

Jansen, R., Batista, S., Brooks, A. I., Tischfield, J. A., Willemsen, G., Grootheest, G., Hottenga, J. J., Milaneschi, Y., Mbarek, H., Madar, V., Peyrot, W., Vink, J. M., Verweij, C. L., de Geus, E. J. C., Smit, J. H., Wright, F. A., Sullivan, P. F., Boomsma, D. I. & Penninx, B. W. J. H., 2014, In : BMC Genomics. 15, p. 33 12 p., 33.

Research output: Contribution to journalArticleAcademicpeer-review

2013

Collaborative stepped care v. care as usual for common mental disorders: 8-month, cluster randomised controlled trial

Oosterbaan, D. B., Verbraak, M. J. P. M., Terluin, B., Hoogendoorn, A. W., Peyrot, W., Muntingh, A. D. T. & van Balkom, A. J. L. M., 2013, In : British Journal of Psychiatry. 203, 2, p. 132-139

Research output: Contribution to journalArticleAcademicpeer-review

GWAS of 126559 Individuals Identifies Genetic Variants Associated with Educational Attainment

Rietveld, C. A., Medland, S. E., Derringer, J., Yang, J., Esko, T., Martin, N. W., Westra, H. J., Shakhbazov, K., Abdellaoui, A., Agrawal, A., Albrecht, E., Alizadeh, BZ., Amin, N., Barnard, J., Baumeister, S. E., Benke, K. S., Bielak, L. F., Boatman, J. A., Boyle, P. A., Davies, G. & 182 othersde Leeuw, C. A., Eklund, N., Evans, D. S., Fehrmann, R. S., Fischer, K., Gieger, C., Gjessing, H. K., Hägg, S., Harris, J. R., Hayward, C., Holzapfel, C., Ibrahim-Verbaas, C. A., Ingelsson, E., Jacobsson, B., Joshi, P. K., Jugessur, A., Kaakinen, M., Kanoni, S., Karjalainen, J., Kolcic, I., Kristiansson, K., Kutalik, Z., Lahti, J., Lee, S. H., Lin, P., Lind, P. A., Liu, Y., Lohman, K., Loitfelder, M., McMahon, G., Vidal, P. M., Meirelles, O., Milani, L., Myhre, R., Nuotio, M. L., Oldmeadow, C. J., Petrovic, K. E., Peyrot, W. J., Polasek, O., Quaye, L., Reinmaa, E., Rice, J. P., Rizzi, T. S., Schmidt, H., Schmidt, R., Smith, A. V., Smith, J. A., Tanaka, T., Terracciano, A., van der Loos, M. J., Vitart, V., Völzke, H., Wellmann, J., Yu, L., Zhao, W., Allik, J., Attia, J. R., Bandinelli, S., Bastardot, F., Beauchamp, J., Bennett, D. A., Berger, K., Bierut, L. J., Boomsma, D. I., Bültmann, U., Campbell, H., Chabris, C. F., Cherkas, L., Chung, M. K., Cucca, F., de Andrade, M., Jager, P. L., de Neve, J. E., Deary, I. J., Dedoussis, G. V., Deloukas, P., Dimitriou, M., Eiriksdottir, G., Elderson, M. F., Eriksson, J. G., Evans, D. M., Faul, J. D., Ferrucci, L., Garcia, M. E., Grönberg, H., Gudnason, V., Hall, P., Harris, J. M., Harris, T. B., Hastie, N. D., Heath, A. C., Hernandez, D. G., Hoffmann, W., Hofman, A., Holle, R., Holliday, E. G., Hottenga, J. J., Iacono, W. G., Illig, T., Järvelin, M. R., Kähönen, M., Kaprio, J., Kirkpatrick, R. M., Kowgier, M., Latvala, A., Launer, L. J., Lawlor, D. A., Lehtimäki, T., Li, J., Lichtenstein, P., Lichtner, P., Liewald, D. C., Madden, P. A. F., Magnusson, P. K. E., Mäkinen, T. E., Masala, M., McGue, M., Metspalu, A., Mielck, A., Miller, M. B., Montgomery, G. W., Mukherjee, S., Nyholt, DR., Oostra, B. A., Palmer, L. J., Palotie, A., Penninx, B. W. J. H., Perola, M., Peyser, P. A., Preisig, M., Räikkönen, K., Raitakari, O. T., Realo, A., Ring, S. M., Ripatti, S., Rivadeneira, F., Rudan, I., Rustichini, A., Salomaa, V., Sarin, A. P., Schlessinger, D., Scott, R. J., Snieder, H., St Pourcain, B., Starr, J. M., Sul, J. H., Surakka, I., Svento, R., Teumer, A., Tiemeier, H., van Rooij, F. J., Wagoner, D. R., Vartiainen, E., Viikari, J., Vollenweider, P., Vonk, J. M., Waeber, G., Weir, D. R., Wichmann, H. E., Widen, E., Willemsen, G., Wilson, J. F., Wright, A. F., Conley, D., Davey Smith, G., Franke, L., Groenen, P. J. F., Johannesson, M., Kardia, S., Krueger, R. F., Laibson, D., Martin, N. G., Meyer, M. N., Posthuma, D., Thurik, A. R., Timpson, N. J., Uitterlinden, A. G., van Duijn, C. M., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 2013, In : Science. 340, 6139, p. 1467-1471

Research output: Contribution to journalArticleAcademicpeer-review

Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample

Peyrot, W., Middeldorp, C. M., Jansen, R., Smit, J. H., de Geus, E. J. C., Hottenga, J. J., Willemsen, G., Vink, J. M., Virding, S., Barragan, I., Ingelman-Sundberg, M., Sim, S. C., Boomsma, D. I. & Penninx, B. W. J. H., 2013, In : Journal of Affective Disorders. 146, 1, p. 91-99

Research output: Contribution to journalArticleAcademicpeer-review