Projects per year
Personal profile
Specialisation
Psychiatric Epidemiology
Research interests
I studied and trained in clinical psychology and psychotherapy in Italy. Subsequently, I worked in the field of epidemiology of aging in Italy (InCHIANTI Study 2007-2010) and the USA (National Institute of Aging, 2010-2012). Due to the enriching experience in such diverse contexts my research perspective became inherently multidisciplinary. My main research theme is the study, using the tools of epidemiology, of biological pathways that may have a role in the pathophysiology of depression.
At the Department of Psychiatry of Amsterdam UMC, where I am currently assistant professor of psychiatry and epidemiology, I further developed the investigation of the immuno-metabolic biological pathways involved in depression. Furthermore, I embraced the exciting developments of the genomics era, expanding my skills and moving my research questions beyond the study of biomarkers of depression toward its genetic basis. I wrote invited expert reviews on genetic research in depression, the biological mechanisms connecting depression and obesity and, more recently, presenting the concept of “Immuno-Metabolic Depression”
I am currently member of the The Scientific Quality Committee (SQC) of Amsterdam Public Health and co-PI of the new INFLAMED trial testing anti-inflammatory add-on in the treatment of Immuno-Metabolic Depression
Network
Projects
- 2 Active
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inflaMED: Precision psychiatry: Anti-inflammatory medication in Immuno-metabolic depression
Lamers, F., Milaneschi, Y., Penninx, B., Vinkers, C. & Zwiep, J.
01/09/2021 → 31/08/2025
Project: Research
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PERCIM: Personalized Care for Depression: Bringing Immuno-Metabolic Depression from Bench to Bedside
Lamers, F., Jansen, R., Vreijling, S., Penninx, B., Beekman, A., Bot, M., Milaneschi, Y., Bremmer, M. & Rhebergen, D.
01/10/2019 → 30/09/2023
Project: Research
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Depression Heterogeneity and Its Biological Underpinnings: Toward Immunometabolic Depression
Milaneschi, Y., Lamers, F., Berk, M. & Penninx, B. W. J. H., 1 Sep 2020, In: Biological Psychiatry. 88, 5, p. 369-380 12 p.Research output: Contribution to journal › Review article › Academic › peer-review
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Depression and obesity: evidence of shared biological mechanisms
Milaneschi, Y., Simmons, W. K., van Rossum, E. F. C. & Penninx, B. WJH., 1 Jan 2019, In: Molecular Psychiatry. 24, 1, p. 18-33 16 p.Research output: Contribution to journal › Review article › Academic › peer-review
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Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations
Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., Lewis, C., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rivera, M., Rietschel, M., Streit, F., Strohmaier, J., Teumer, A., & 5 others , 1 Dec 2017, In: JAMA Psychiatry. 74, 12, p. 1214-1225 12 p.Research output: Contribution to journal › Article › Academic › peer-review
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Metabolomics dissection of depression heterogeneity and related cardiometabolic risk
Alshehri, T., Mook- Kanamori, D. O., Willems van Dijk, K., Dinga, R., Penninx, B. W. J. H., Rosendaal, F. R., le Cessie, S. & Milaneschi, Y., 3 Jan 2023, In: Psychological Medicine. 53, 1, p. 248-257 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics
Milaneschi, Y., Peyrot, W. J., Nivard, M. G., Mbarek, H., Boomsma, D. I. & W.J.H. Penninx, B., 1 Dec 2019, In: Translational Psychiatry. 9, 1, 219.Research output: Contribution to journal › Article › Academic › peer-review
Open Access