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Research Output 1989 2019

2015

MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients

Lenos, K. J., Goos, J. A. C. M., Vuist, I. M., den Uil, S. H., Delis-van Diemen, P. M., Belt, E. J. T., Stockmann, H. B. A. C., Bril, H., de Wit, M., Carvalho, B., Giblett, S., Pritchard, C. A., Meijer, G. A., van Kooyk, Y., Fijneman, R. J. A. & van Vliet, S. J., 2015, In : Oncotarget. 6, 28, p. 26278-26290

Research output: Contribution to journalArticleAcademicpeer-review

MPLA incorporation into DC-targeting glycoliposomes favours anti-tumour T cell responses

Boks, M. A., Ambrosini, M., Bruijns, S. C. M., Kalay, H., van Bloois, L., Storm, G., Garcia Vallejo, J. J. & van Kooyk, Y., 2015, In : Journal of Controlled Release. 216, p. 37-46

Research output: Contribution to journalArticleAcademicpeer-review

Novel insights into the immunomodulatory role of the dendritic cell and macrophage-expressed C-type lectin MGL

van Kooyk, Y., Ilarregui, J. M. & van Vliet, S. J., 2015, In : Immunobiology. 220, 2, p. 185-192

Research output: Contribution to journalArticleAcademicpeer-review

Phenotypic and Functional Properties of Human Steady State CD14(+) and CD1a(+) Antigen Presenting Cells and Epidermal Langerhans Cells

Fehres, C. M., Bruijns, S. C. M., Sotthewes, B. N., Kalay, H., Schaffer, L., Head, S. R., de Gruijl, T. D., Garcia Vallejo, J. J. & van Kooyk, Y., 2015, In : PLoS ONE. 10, 11, e0143519.

Research output: Contribution to journalArticleAcademicpeer-review

The primate autoimmune encephalomyelitis model; a bridge between mouse and man

't Hart, B., van Kooyk, Y., Geurts, J. J. G. & Gran, B., 2015, In : Annals of Clinical and Translational Neurology. 2, 5, p. 581-593

Research output: Contribution to journalArticleAcademicpeer-review

57 Downloads (Pure)

The Sweet and Sorrow of Pancreatic cancer: Galectin-4 and glycosylation in pancreatic cancer

da Silva Aresta Belo van Wijk, A. I., 2015

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File

Trypanosoma cruzi Infection Imparts a Regulatory Program in Dendritic Cells and T Cells via Galectin-1-Dependent Mechanisms

Poncini, C. V., Ilarregui, J. M., Batalla, E. I., Engels, S., Cerliani, J. P., Cucher, M. A., van Kooyk, Y., Gonzalez-Cappa, S. M. & Rabinovich, G. A., 2015, In : Journal of Immunology. 195, 7, p. 3311-3324

Research output: Contribution to journalArticleAcademicpeer-review

2014

CNS myelin induces regulatory functions of DC-SIGN-expressing, antigen-presenting cells via cognate interaction with MOG

Garcia-Vallejo, J. J., Ilarregui, J. M., Kalay, H., Chamorro, S., Koning, N., Unger, W. W. J., Ambrosini, M., Montserrat, V., Fernandes, R. J., Bruijns, S. C. M., van Weering, J. R. T., Paauw, N. J., O'Toole, T. G., van Horssen, J., van der Valk, P., Nazmi, K., Bolscher, J. G., Bajramovic, J., Dijkstra, C. D., 't Hart, B. A. & 1 othersvan Kooyk, Y., 2014, In : Journal of Experimental Medicine. 211, 7, p. 1465-1483

Research output: Contribution to journalArticleAcademicpeer-review

DCIR interacts with ligands from both endogenous and pathogenic origin

Bloem, K., Vuist, I. M., van den Berk, M., Klaver, E. J., van Die, I. M., Knippels, L. M., Garssen, J., Garcia Vallejo, J. J., van Vliet, S. J. & van Kooijk, Y., 2014, In : Immunology Letters. 158, 1-2, p. 33-41

Research output: Contribution to journalArticleAcademicpeer-review

Effective Targeting of DC-SIGN by alpha-Fucosylamide Functionalized Gold Nanoparticles

Arosio, D., Chiodo, F., Reina, J. J., Marelli, M., Penades, S., van Kooijk, Y., Garcia Vallejo, J. J. & Bernardi, A., 2014, In : Bioconjugate chemistry. 25, 12, p. 2244-2251

Research output: Contribution to journalArticleAcademicpeer-review

Effects of Antigen-Expressing Immunostimulatory Liposomes on Chemotaxis and Maturation of Dendritic Cells In Vitro and in Human Skin Explants

Lanzi, A., Fehres, C. M., de Gruijl, T. D., van Kooijk, Y. & Mastrobattista, E., 2014, In : Pharmaceutical Research. 31, 2, p. 516-526

Research output: Contribution to journalArticleAcademicpeer-review

Topical rather than intradermal application of the TLR7 ligand imiquimod leads to human dermal dendritic cell maturation and CD8(+) T-cell cross-priming

Fehres, C. M., Bruijns, S. C. M., van Beelen, A. J., Kalay, H., Ambrosini, M., Hooijberg, E., Unger, W. W. J., de Gruijl, T. D. & van Kooijk, Y., 2014, In : European Journal of Immunology. 44, 8, p. 2415-2424

Research output: Contribution to journalArticleAcademicpeer-review

Understanding the biology of antigen cross-presentation for the design of vaccines against cancer

Fehres, C. M., Unger, W. W. J., Garcia Vallejo, J. J. & van Kooijk, Y., 2014, In : Frontiers in Microbiology. 5, 149.

Research output: Contribution to journalArticleAcademicpeer-review

Antigen-Presenting Cells in the Central Nervous System

Koning, N., Ilarregui, J. M., Garcia Vallejo, J. J. & van Kooijk, Y., 2013, Multiple Sclerosis Immunology. p. 71-94

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

38 Downloads (Pure)

C-type lectins and their role in the immune system: New insights into the characteristics of DCIR and DC-SIGN

Bloem, K., 2013

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File

Glycan-based DC-SIGN targeting to enhance antigen cross-presentation in anticancer vaccines

Garcia Vallejo, J. J., Unger, W. W. J., Kalay, H. & van Kooijk, Y., 2013, In : OncoImmunology. 2, 2, e23040.

Research output: Contribution to journalArticleAcademicpeer-review

Glycan-based DC-SIGN targeting vaccines to enhance antigen cross-presentation

van Kooijk, Y., Unger, W. W. J., Fehres, C. M., Kalay, H. & Garcia Vallejo, J. J., 2013, In : Molecular Immunology. 55, 2, p. 143-145

Research output: Contribution to journalArticleAcademicpeer-review

Glycodendrimers prevent HIV transmission via DC-SIGN on dendritic cells

Garcia Vallejo, J. J., Koning, N., Ambrosini, M., Kalay, H., Vuist, I., Sarrami-Forooshani, R., Geijtenbeek, T. B. H. & van Kooijk, Y., 2013, In : International Immunology. 25, 4, p. 221-233

Research output: Contribution to journalArticleAcademicpeer-review

How mucins shape antigen-presenting cells to modify immune responses

van Vliet, S. J. & van Kooijk, Y., 2013, Mucins and Cancer. p. 108-122

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Intestinal Epithelium-Derived Galectin-9 Is Involved in the Immunomodulating Effects of Nondigestible Oligosaccharides

de Kivita, S., Kraneveld, A. D., Knippels, L. M. J., van Kooijk, Y., Garssen, J. & Willemsen, L. E. M., 2013, In : Journal of innate immunity. 5, 6, p. 625-638

Research output: Contribution to journalArticleAcademicpeer-review

Intradermal Delivery of TLR Agonists in a Human Explant Skin Model: Preferential Activation of Migratory Dendritic Cells by Polyribosinic-Polyribocytidylic Acid and Peptidoglycans

Oosterhoff, D., Heusinkveld, M., Lougheed, S. M., Kosten, I., Lindstedt, M., Bruijns, S. C. M., van Es, T., van Kooijk, Y., van der Burg, S. H. & de Gruijl, T. D., 2013, In : Journal of Immunology. 190, 7, p. 3338-3345

Research output: Contribution to journalArticleAcademicpeer-review

In vivo targeting of human DC-SIGN drastically enhances CD8(+) T-cell-mediated protective immunity

Hesse, C., Ginter, W., Forg, T., Mayer, C. T., Baru, A. M., Arnold-Schrauf, C., Unger, W. W. J., Kalay, H., van Kooijk, Y., Berod, L. & Sparwasser, T., 2013, In : European Journal of Immunology. 43, 10, p. 2543-2553

Research output: Contribution to journalArticleAcademicpeer-review

Ligand Binding and Signaling of Dendritic Cell Immunoreceptor (DCIR) Is Modulated by the Glycosylation of the Carbohydrate Recognition Domain

Bloem, K., Vuist, I. M., van der Plas, A. J., Knippels, L. M. J., Garssen, J., Garcia Vallejo, J. J., van Vliet, S. J. & van Kooijk, Y., 2013, In : PLoS ONE. 8, 6, e66266.

Research output: Contribution to journalArticleAcademicpeer-review

MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-alpha secretion

van Vliet, S. J., Bay, S., Vuist, I. M., Kalay, H., Garcia Vallejo, J. J., Leclerc, C. & van Kooijk, Y., 2013, In : Journal of Leukocyte Biology. 94, 2, p. 315-323

Research output: Contribution to journalArticleAcademicpeer-review

Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells

Garcia Vallejo, J. J., Ambrosini, M., Overbeek, A., van Riel, W. E., Bloem, K., Unger, W. W. J., Chiodo, F., Bolscher, J. G., Nazmi, K., Kalay, H. & van Kooijk, Y., 2013, In : Molecular Immunology. 53, 4, p. 387-397

Research output: Contribution to journalArticleAcademicpeer-review

Notch controls generation and function of human effector CD8+ T cells

Kuijk, L. M., Verstege, M. I., Rekers, N. V., Bruijns, S. C. M., Hooijberg, E., Roep, B. O., de Gruijl, T. D., van Kooijk, Y. & Unger, W. W. J., 2013, In : Blood. 121, 14, p. 2638-2646

Research output: Contribution to journalArticleAcademicpeer-review

Skin-resident antigen-presenting cells: instruction manual for vaccine development

Fehres, C. M., Garcia Vallejo, J. J., Unger, W. W. J. & van Kooijk, Y., 2013, In : Frontiers in Immunology: Molecular Innate Immunity. 4, 157.

Research output: Contribution to journalArticleAcademicpeer-review

The physiological role of DC-SIGN: A tale of mice and men

Garcia Vallejo, J. J. & van Kooijk, Y., 2013, In : Trends in Immunology. 34, 10, p. 482-486

Research output: Contribution to journalArticleAcademicpeer-review

2012

BODIPY-Labeled DC-SIGN-Targeting Glycodendrons Efficiently Internalize and Route to Lysosomes in Human Dendritic Cells

Ribeiro-Viana, R., Garcia Vallejo, J. J., Collado, D., Perez-Inestrosa, E., Bloem, K., van Kooijk, Y. & Rojo, J., 2012, In : Biomacromolecules. 13, 10, p. 3209-3219

Research output: Contribution to journalArticleAcademicpeer-review

Differential glycosylation of MUC1 and CEACAM5 between normal mucosa and tumour tissue of colon cancer patients

Saeland, E., Da Silva Aresta Belo, A. I., Mongera, S., van Die, I. M., Meijer, G. A. & van Kooijk, Y., 2012, In : International Journal of Cancer. 131, 1, p. 117-128

Research output: Contribution to journalArticleAcademicpeer-review

Galectin-9 induced by dietary synbiotics is involved in suppression of allergic symptoms in mice and humans

de Kivit, S., Saeland, E., Kraneveld, A. D., van de Kant, H. J. G., Schouten, B., van Esch, B. C. A. M., Knol, J., Sprikkelman, A. B., van der Aa, L. B., Knippels, L. M. J., Garssen, J., van Kooijk, Y. & Willemsen, L. E. M., 2012, In : Allergy. 67, 3, p. 343-352

Research output: Contribution to journalArticleAcademicpeer-review

Glycan-modified liposomes boost CD4(+) and CD8(+) T-cell responses by targeting DC-SIGN on dendritic cells

Unger, W. W. J., van Beelen, A. J., Bruijns, S. C. M., Joshi, M., Fehres, C. M., van Bloois, L., Verstege, M. I., Ambrosini, M., Kalay, H., Nazmi, K., Bolscher, J. G., Hooijberg, E., de Gruijl, T. D., Storm, G. & van Kooijk, Y., 2012, In : Journal of Controlled Release. 160, 1, p. 88-95

Research output: Contribution to journalArticleAcademicpeer-review

Glycobiology of immune responses

Rabinovich, G. A., van Kooijk, Y. & Cobb, B. A., 2012, In : Annals of the New York Academy of Sciences. 1253, p. 1-15

Research output: Contribution to journalArticleAcademicpeer-review

Online nanoliquid chromatography-mass spectrometry and nanofluorescence detection for high-resolution quantitative N-glycan analysis

Kalay, H., Ambrosini, M., van Berkel, P. H. C., Parren, P. W. H. I., van Kooijk, Y. & Garcia Vallejo, J. J., 2012, In : Analytical Biochemistry. 423, 1, p. 153-162

Research output: Contribution to journalArticleAcademicpeer-review

Specific glycan elements determine differential binding of individual egg glycoproteins of the human parasite Schistosoma mansoni by host C-type lectin receptors

Meevissen, M. H. J., Driessen, N. N., Smits, H. H., Versteegh, R., van Vliet, S. J., van Kooijk, Y., Schramm, G., Deelder, A. M., de Haas, H., Yazdanbakhsh, M. & Hokke, C. H., 2012, In : International Journal for Parasitology. 42, 3, p. 269-277

Research output: Contribution to journalArticleAcademicpeer-review

5 Downloads (Pure)

Sweet modulation of the immune response

Ouwehand, I., 2012

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File

Targeting tumor antigens to dendritic cells using particulate carriers

Joshi, M. D., Unger, W. W. J., Storm, G., van Kooijk, Y. & Mastrobattista, E., 2012, In : Journal of Controlled Release. 161, 1, p. 25-37

Research output: Contribution to journalArticleAcademicpeer-review

2011
21 Downloads (Pure)

Campylobacter jejuni Lipooligosaccharides Modulate Dendritic Cell-Mediated T Cell Polarization in a Sialic Acid Linkage-Dependent Manner

Bax, M., Kuijf, M. L., Heikema, A. P., van Rijs, W., Bruijns, S. C. M., Garcia Vallejo, J. J., Crocker, P. R., Jacobs, B. C., van Vliet, S. J. & van Kooijk, Y., 2011, In : Infection and Immunity. 79, 7, p. 2681-2689

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

C-type Lectin Receptors for Tumor Eradication: Future Directions

Streng-Ouwehand, I., Unger, W. W. J. & Van Kooyk, Y., 8 Aug 2011, In : Cancers. 3, 3, p. 3169-88 20 p.

Research output: Contribution to journalArticleAcademicpeer-review

DC-SIGN mediated antigen-targeting using glycan-modified liposomes: Formulation considerations

Joshi, M. D., Unger, W. W. J., van Beelen, A. J., Bruijns, S. C. M., Litjens, M., van Bloois, L., Kalay, H., van Kooijk, Y. & Storm, G., 2011, In : International journal of pharmaceutics. 416, 2, p. 426-432

Research output: Contribution to journalArticleAcademicpeer-review

Designing polymeric particles for antigen delivery

De Koker, S., Lambrecht, B. N., Willart, M. A., van Kooijk, Y., Grooten, J., Vervaet, C., Remon, J. P. & De Geest, B. G., 2011, In : Chemical Society Reviews. 40, 1, p. 320-339

Research output: Contribution to journalArticleAcademicpeer-review

Design of neo-glycoconjugates that target the mannose receptor and enhance TLR-independent cross-presentation and Th1 polarization

Singh, S. K., Ouwehand, I., Litjens, M., Kalay, H., Burgdorf, S., Saeland, E., Kurts, C., Unger, W. W. J. & van Kooijk, Y., 2011, In : European Journal of Immunology. 41, 4, p. 916-925

Research output: Contribution to journalArticleAcademicpeer-review

'Dressed for success' C-type lectin receptors for the delivery of glyco-vaccines to dendritic cells

Unger, W. W. J. & van Kooijk, Y., 2011, In : Current Opinion in Immunology. 23, 1, p. 131-137

Research output: Contribution to journalArticleAcademicpeer-review

20 Downloads (Pure)

Galactosaminogalactan, a New Immunosuppressive Polysaccharide of Aspergillus fumigatus

Fontaine, T., Delangle, A., Simenel, C., Coddeville, B., van Vliet, S. J., van Kooijk, Y., Bozza, S., Moretti, S., Schwarz, F., Trichot, C., Aebi, M., Delepierre, M., Elbim, C., Romani, L. & Latge, J. P., 2011, In : PLoS Pathogens. 7, 11, e1002372.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Highly glycosylated tumour antigens: interactions with the immune system

Saeland, E. & van Kooijk, Y., 2011, In : Biochemical Society Transactions. 39, p. 388-392

Research output: Contribution to journalArticleAcademicpeer-review