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Research Output 1989 2019

2003

Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy

Kämmerer, U., Eggert, A. O., Kapp, M., McLellan, A. D., Geijtenbeek, T. B. H., Dietl, J., van Kooyk, Y. & Kämpgen, E., Mar 2003, In : The American Journal of Pathology. 162, 3, p. 887-96 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2002

Accumulation of DC-SIGN+CD40+ dendritic cells with reduced CD80 and CD86 expression in lymphoid tissue during acute HIV-1 infection

Loré, K., Sönnerborg, A., Broström, C., Goh, L-E., Perrin, L., McDade, H., Stellbrink, H-J., Gazzard, B., Weber, R., Napolitano, L. A., van Kooyk, Y. & Andersson, J., 29 Mar 2002, In : AIDS. 16, 5, p. 683-92 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

A novel adhesion pathway that regulates dendritic cell trafficking and T cell interactions

van Kooyk, Y. & Geijtenbeek, T. B. H., Aug 2002, In : Immunological Reviews. 186, p. 47-56 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Chemokine stimulation of lymphocyte alpha 4 integrin avidity but not of leukocyte function-associated antigen-1 avidity to endothelial ligands under shear flow requires cholesterol membrane rafts

Shamri, R., Grabovsky, V., Feigelson, S. W., Dwir, O., Van Kooyk, Y. & Alon, R., 18 Oct 2002, In : Journal of Biological Chemistry. 277, 42, p. 40027-35 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

C-type lectin receptors on dendritic cells and Langerhans cells

Figdor, C. G., van Kooyk, Y. & Adema, G. J., Feb 2002, In : Nature Reviews Immunology. 2, 2, p. 77-84 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

DC-SIGN, a C-type lectin on dendritic cells that unveils many aspects of dendritic cell biology

Geijtenbeek, T. B. H., Engering, A. & Van Kooyk, Y., Jun 2002, In : Journal of Leukocyte Biology. 71, 6, p. 921-31 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Enhancement of G-CSF-induced stem cell mobilization by antibodies against the beta 2 integrins LFA-1 and Mac-1

Velders, G. A., Pruijt, J. F. M., Verzaal, P., van Os, R., van Kooyk, Y., Figdor, C. G., de Kruijf, E-J. F. M., Willemze, R. & Fibbe, W. E., 1 Jul 2002, In : Blood. 100, 1, p. 327-33 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

HIV-1 Nef-induced upregulation of DC-SIGN in dendritic cells promotes lymphocyte clustering and viral spread

Sol-Foulon, N., Moris, A., Nobile, C., Boccaccio, C., Engering, A., Abastado, J-P., Heard, J-M., van Kooyk, Y. & Schwartz, O., Jan 2002, In : Immunity. 16, 1, p. 145-55 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1

Geijtenbeek, T. B. H., van Duijnhoven, G. C. F., van Vliet, S. J., Krieger, E., Vriend, G., Figdor, C. G. & van Kooyk, Y., 29 Mar 2002, In : Journal of Biological Chemistry. 277, 13, p. 11314-20 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Immune escape through C-type lectins on dendritic cells

Engering, A., Geijtenbeek, T. B. H. & van Kooyk, Y., Oct 2002, In : Trends in Immunology. 23, 10, p. 480-5 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development

Smits, H. H., de Jong, E. C., Schuitemaker, J. H. N., Geijtenbeek, T. B. H., van Kooyk, Y., Kapsenberg, M. L. & Wierenga, E. A., 15 Feb 2002, In : Journal of Immunology. 168, 4, p. 1710-6 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Marginal zone macrophages express a murine homologue of DC-SIGN that captures blood-borne antigens in vivo

Geijtenbeek, T. B. H., Groot, P. C., Nolte, M. A., van Vliet, S. J., Gangaram-Panday, S. T., van Duijnhoven, G. C. F., Kraal, G., van Oosterhout, A. J. M. & van Kooyk, Y., 15 Oct 2002, In : Blood. 100, 8, p. 2908-16 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Subset of DC-SIGN(+) dendritic cells in human blood transmits HIV-1 to T lymphocytes

Engering, A., Van Vliet, S. J., Geijtenbeek, T. B. H. & Van Kooyk, Y., 1 Sep 2002, In : Blood. 100, 5, p. 1780-6 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells

Engering, A., Geijtenbeek, T. B. H., van Vliet, S. J., Wijers, M., van Liempt, E., Demaurex, N., Lanzavecchia, A., Fransen, J., Figdor, C. G., Piguet, V. & van Kooyk, Y., 1 Mar 2002, In : Journal of Immunology. 168, 5, p. 2118-26 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2001

A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection

Bashirova, A. A., Geijtenbeek, T. B., van Duijnhoven, G. C., van Vliet, S. J., Eilering, J. B., Martin, M. P., Wu, L., Martin, T. D., Viebig, N., Knolle, P. A., KewalRamani, V. N., van Kooyk, Y. & Carrington, M., 19 Mar 2001, In : Journal of Experimental Medicine. 193, 6, p. 671-8 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

A single amino acid in the cytoplasmic domain of the beta 2 integrin lymphocyte function-associated antigen-1 regulates avidity-dependent inside-out signaling

Bleijs, D. A., van Duijnhoven, G. C., van Vliet, S. J., Thijssen, J. P., Figdor, C. G. & van Kooyk, Y., 30 Mar 2001, In : Journal of Biological Chemistry. 276, 13, p. 10338-46 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

DC-SIGN, a dentritic cell-specific HIV-1 receptor present in placenta that infects T cells in trans-a review

Geijtenbeek, T. B., van Vliet, S. J., van Duijnhoven, G. C., Figdor, C. G. & van Kooyk, Y., Apr 2001, In : Placenta. 22 Suppl A, p. S19-23

Research output: Contribution to journalReview articleAcademicpeer-review

DC-SIGN and LFA-1: a battle for ligand

Bleijs, D. A., Geijtenbeek, T. B., Figdor, C. G. & van Kooyk, Y., Aug 2001, In : Trends in Immunology. 22, 8, p. 457-63 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Heme-induced cell adhesion in the pathogenesis of sickle-cell disease and inflammation

Wagener, F. A., Abraham, N. G., van Kooyk, Y., de Witte, T. & Figdor, C. G., Feb 2001, In : Trends in Pharmacological Sciences. 22, 2, p. 52-4 3 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase

Wagener, F. A., Eggert, A., Boerman, O. C., Oyen, W. J., Verhofstad, A., Abraham, N. G., Adema, G., van Kooyk, Y., de Witte, T. & Figdor, C. G., 15 Sep 2001, In : Blood. 98, 6, p. 1802-11 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Rhesus macaque and chimpanzee DC-SIGN act as HIV/SIV gp120 trans-receptors, similar to human DC-SIGN

Geijtenbeek, T. B., Koopman, G., van Duijnhoven, G. C., van Vliet, S. J., van Schijndel, A. C., Engering, A., Heeney, J. L. & van Kooyk, Y., 1 Nov 2001, In : Immunology Letters. 79, 1-2, p. 101-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

The N-terminal region and the mid-region complex of the integrin beta 2 subunit

Tan, S. M., Robinson, M. K., Drbal, K., van Kooyk, Y., Shaw, J. M. & Law, S. K., 28 Sep 2001, In : Journal of Biological Chemistry. 276, 39, p. 36370-6 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2000

Avidity regulation of integrins: the driving force in leukocyte adhesion

van Kooyk, Y. & Figdor, C. G., Oct 2000, In : Current opinion in cell biology. 12, 5, p. 542-7 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Cytohesin-1 regulates beta-2 integrin-mediated adhesion through both ARF-GEF function and interaction with LFA-1

Geiger, C., Nagel, W., Boehm, T., van Kooyk, Y., Figdor, C. G., Kremmer, E., Hogg, N., Zeitlmann, L., Dierks, H., Weber, K. S. & Kolanus, W., 1 Jun 2000, In : EMBO Journal. 19, 11, p. 2525-36 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

Geijtenbeek, T. B., Kwon, D. S., Torensma, R., van Vliet, S. J., van Duijnhoven, G. C., Middel, J., Cornelissen, I. L., Nottet, H. S., KewalRamani, V. N., Littman, D. R., Figdor, C. G. & van Kooyk, Y., 3 Mar 2000, In : Cell. 100, 5, p. 587-97 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking

Geijtenbeek, T. B., Krooshoop, D. J., Bleijs, D. A., van Vliet, S. J., van Duijnhoven, G. C., Grabovsky, V., Alon, R., Figdor, C. G. & van Kooyk, Y., Oct 2000, In : Nature Immunology. 1, 4, p. 353-7 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Dynamic regulation of activated leukocyte cell adhesion molecule-mediated homotypic cell adhesion through the actin cytoskeleton

Nelissen, J. M., Peters, I. M., de Grooth, B. G., van Kooyk, Y. & Figdor, C. G., Jun 2000, In : Molecular Biology of the Cell. 11, 6, p. 2057-68 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses

Geijtenbeek, T. B., Torensma, R., van Vliet, S. J., van Duijnhoven, G. C., Adema, G. J., van Kooyk, Y. & Figdor, C. G., 3 Mar 2000, In : Cell. 100, 5, p. 575-85 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Low-affinity LFA-1/ICAM-3 interactions augment LFA-1/ICAM-1-mediated T cell adhesion and signaling by redistribution of LFA-1

Bleijs, D. A., Binnerts, M. E., van Vliet, S. J., Figdor, C. G. & van Kooyk, Y., Feb 2000, In : Journal of Cell Science. 113 ( Pt 3), p. 391-400 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Medium-chain, triglyceride-containing lipid emulsions increase human neutrophil beta2 integrin expression, adhesion, and degranulation

Wanten, G. J., Geijtenbeek, T. B., Raymakers, R. A., van Kooyk, Y., Roos, D., Jansen, J. B. & Naber, A. H., 8 Jul 2000, In : Journal of Parenteral and Enteral Nutition. 24, 4, p. 228-33 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Molecular analysis of the hematopoiesis supporting osteoblastic cell line U2-OS

Nelissen, J. M., Torensma, R., Pluyter, M., Adema, G. J., Raymakers, R. A., van Kooyk, Y. & Figdor, C. G., Apr 2000, In : Experimental Hematology. 28, 4, p. 422-32 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Regulation of LFA-1 Expression by CD34 Positive Cells and Inducible Growth Factor Production by Stroma Enable Formation of Bone Marrow Compartments; Subject Heading

Torensma, R., Nelissen, J. M., van Kooyk, Y., Raymakers, R. A. P., Pennings, A. H. M., de Witte, T. & Figdor, C. G., 2000, In : Haematologica. 5, 4, p. 295-302 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environment

Sigal, A., Bleijs, D. A., Grabovsky, V., van Vliet, S. J., Dwir, O., Figdor, C. G., van Kooyk, Y. & Alon, R., 1 Jul 2000, In : Journal of Immunology. 165, 1, p. 442-52 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

The role of metalloproteinases and adhesion molecules in interleukin-8-induced stem-cell mobilization

Fibbe, W. E., Pruijt, J. F., van Kooyk, Y., Figdor, C. G., Opdenakker, G. & Willemze, R., Jan 2000, In : Seminars in Hematology. 37, 1 Suppl 2, p. 19-24 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

Reedquist, K. A., Ross, E., Koop, E. A., Wolthuis, R. M., Zwartkruis, F. J., van Kooyk, Y., Salmon, M., Buckley, C. D. & Bos, J. L., 20 Mar 2000, In : Journal of Cell Biology. 148, 6, p. 1151-8 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1999

3D single-particle tracking and optical trap measurements on adhesion proteins

Peters, I. M., van Kooyk, Y., van Vliet, S. J., de Grooth, B. G., Figdor, C. G. & Greve, J., 1 Jul 1999, In : Cytometry Part B. Clinical Cytometry. 36, 3, p. 189-94 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biology of IL-8-induced stem cell mobilization

Fibbe, W. E., Pruijt, J. F., Velders, G. A., Opdenakker, G., van Kooyk, Y., Figdor, C. G. & Willemze, R., 30 Apr 1999, In : Annals of the New York Academy of Sciences. 872, p. 71-82 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Co-stimulation of T cells results in distinct IL-10 and TNF-alpha cytokine profiles dependent on binding to ICAM-1, ICAM-2 or ICAM-3

Bleijs, D. A., de Waal-Malefyt, R., Figdor, C. G. & van Kooyk, Y., Jul 1999, In : European Journal of Immunology. 29, 7, p. 2248-58 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

High frequency of adhesion defects in B-lineage acute lymphoblastic leukemia

Geijtenbeek, T. B., van Kooyk, Y., van Vliet, S. J., Renes, M. H., Raymakers, R. A. & Figdor, C. G., 15 Jul 1999, In : Blood. 94, 2, p. 754-64 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

How LFA-1 binds to different ligands

Binnerts, M. E. & van Kooyk, Y., May 1999, In : Immunology today. 20, 5, p. 240-5 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

H-Ras signals to cytoskeletal machinery in induction of integrin-mediated adhesion of T cells

Tanaka, Y., Minami, Y., Mine, S., Hirano, H., Hu, C. D., Fujimoto, H., Fujii, K., Saito, K., Tsukada, J., van Kooyk, Y., Figdor, C. G., Kataoka, T. & Eto, S., 1 Dec 1999, In : Journal of Immunology. 163, 11, p. 6209-16 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Murine hematopoietic progenitor cells with colony-forming or radioprotective capacity lack expression of the beta 2-integrin LFA-1

Pruijt, J. F., van Kooyk, Y., Figdor, C. G., Willemze, R. & Fibbe, W. E., 1 Jan 1999, In : Blood. 93, 1, p. 107-12 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

The actin cytoskeleton regulates LFA-1 ligand binding through avidity rather than affinity changes

van Kooyk, Y., van Vliet, S. J. & Figdor, C. G., 17 Sep 1999, In : Journal of Biological Chemistry. 274, 38, p. 26869-77 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

1998

Adhesion and signaling mediated by the cytoplasmic tails of leucocyte integrins

van Kooyk, Y., Lub, M. & Figdor, C. G., 1998, In : Cell adhesion and communication. 6, 2-3, p. 247-54 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Anti-LFA-1 blocking antibodies prevent mobilization of hematopoietic progenitor cells induced by interleukin-8

Pruijt, J. F., van Kooyk, Y., Figdor, C. G., Lindley, I. J., Willemze, R. & Fibbe, W. E., 1 Jun 1998, In : Blood. 91, 11, p. 4099-105 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Constitutive chemokine production results in activation of leukocyte function-associated antigen-1 on adult T-cell leukemia cells

Tanaka, Y., Mine, S., Figdor, C. G., Wake, A., Hirano, H., Tsukada, J., Aso, M., Fujii, K., Saito, K., van Kooyk, Y. & Eto, S., 15 May 1998, In : Blood. 91, 10, p. 3909-19 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Constitutive up-regulation of integrin-mediated adhesion of tumor-infiltrating lymphocytes to osteoblasts and bone marrow-derived stromal cells

Tanaka, Y., Mine, S., Hanagiri, T., Hiraga, T., Morimoto, I., Figdor, C. G., van Kooyk, Y., Ozawa, H., Nakamura, T., Yasumoto, K. & Eto, S., 15 Sep 1998, In : Cancer Research. 58, 18, p. 4138-45 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

MEMD, a new cell adhesion molecule in metastasizing human melanoma cell lines, is identical to ALCAM (activated leukocyte cell adhesion molecule)

Degen, W. G., van Kempen, L. C., Gijzen, E. G., van Groningen, J. J., van Kooyk, Y., Bloemers, H. P. & Swart, G. W., Mar 1998, In : The American Journal of Pathology. 152, 3, p. 805-13 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Simultaneous height and adhesion imaging of antibody-antigen interactions by atomic force microscopy

Willemsen, O. H., Snel, M. M., van der Werf, K. O., de Grooth, B. G., Greve, J., Hinterdorfer, P., Gruber, H. J., Schindler, H., van Kooyk, Y. & Figdor, C. G., Nov 1998, In : Biophysical Journal. 75, 5, p. 2220-8 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

1997

Cytoplasmic tails of beta 1, beta 2, and beta 7 integrins differentially regulate LFA-1 function in K562 cells

Lub, M., van Vliet, S. J., Oomen, S. P., Pieters, R. A., Robinson, M., Figdor, C. G. & van Kooyk, Y., Apr 1997, In : Molecular Biology of the Cell. 8, 4, p. 719-28 10 p.

Research output: Contribution to journalArticleAcademicpeer-review