2019 European guideline on the management of lymphogranuloma venereum

H. J. C. de Vries, B. de Barbeyrac, N. H. N. de Vrieze, J. D. Viset, J. A. White, M. Vall-Mayans, M. Unemo

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

New or important issues in this updated version of the 2013 European guideline on the management of lymphogranuloma venereum (LGV): EPIDEMIOLOGY: Lymphogranuloma venereum continues to be endemic among European men who have sex with men (MSM) since 2003. Lymphogranuloma venereum infections in heterosexuals are extremely rare in Europe, and there is no evidence of transmission of LGV in the European heterosexual population. AETIOLOGY AND TRANSMISSION: Chlamydia trachomatis serovars/genovars L2b and L2 are the causative strains in the majority of cases in Europe. CLINICAL FEATURES: Among MSM, about 25% of the anorectal LGV infections are asymptomatic. Genital infections among MSM are rare; the ratio of genital vs. anorectal LGV infections is 1 in 15. DIAGNOSIS: To diagnose LGV, a sample tested C. trachomatis positive with a commercial nucleic acid amplification test (NAAT) platform should be confirmed with an LGV discriminatory NAAT. TREATMENT: Doxycycline 100 mg twice a day orally for 21 days is the recommended treatment for LGV. This same treatment is recommended also in asymptomatic patients and contacts of LGV patients. If another regimen is used, a test of cure (TOC) must be performed.
Original languageEnglish
Pages (from-to)1821-1828
JournalJEADV. Journal of the European Academy of Dermatology and Venereology
Volume33
Issue number10
DOIs
Publication statusPublished - 2019

Cite this

de Vries, H. J. C., de Barbeyrac, B., de Vrieze, N. H. N., Viset, J. D., White, J. A., Vall-Mayans, M., & Unemo, M. (2019). 2019 European guideline on the management of lymphogranuloma venereum. JEADV. Journal of the European Academy of Dermatology and Venereology, 33(10), 1821-1828. https://doi.org/10.1111/jdv.15729
de Vries, H. J. C. ; de Barbeyrac, B. ; de Vrieze, N. H. N. ; Viset, J. D. ; White, J. A. ; Vall-Mayans, M. ; Unemo, M. / 2019 European guideline on the management of lymphogranuloma venereum. In: JEADV. Journal of the European Academy of Dermatology and Venereology. 2019 ; Vol. 33, No. 10. pp. 1821-1828.
@article{5771c3428bad43c8a2e442f30ac20a20,
title = "2019 European guideline on the management of lymphogranuloma venereum",
abstract = "New or important issues in this updated version of the 2013 European guideline on the management of lymphogranuloma venereum (LGV): EPIDEMIOLOGY: Lymphogranuloma venereum continues to be endemic among European men who have sex with men (MSM) since 2003. Lymphogranuloma venereum infections in heterosexuals are extremely rare in Europe, and there is no evidence of transmission of LGV in the European heterosexual population. AETIOLOGY AND TRANSMISSION: Chlamydia trachomatis serovars/genovars L2b and L2 are the causative strains in the majority of cases in Europe. CLINICAL FEATURES: Among MSM, about 25{\%} of the anorectal LGV infections are asymptomatic. Genital infections among MSM are rare; the ratio of genital vs. anorectal LGV infections is 1 in 15. DIAGNOSIS: To diagnose LGV, a sample tested C. trachomatis positive with a commercial nucleic acid amplification test (NAAT) platform should be confirmed with an LGV discriminatory NAAT. TREATMENT: Doxycycline 100 mg twice a day orally for 21 days is the recommended treatment for LGV. This same treatment is recommended also in asymptomatic patients and contacts of LGV patients. If another regimen is used, a test of cure (TOC) must be performed.",
author = "{de Vries}, {H. J. C.} and {de Barbeyrac}, B. and {de Vrieze}, {N. H. N.} and Viset, {J. D.} and White, {J. A.} and M. Vall-Mayans and M. Unemo",
year = "2019",
doi = "10.1111/jdv.15729",
language = "English",
volume = "33",
pages = "1821--1828",
journal = "JEADV. Journal of the European Academy of Dermatology and Venereology",
issn = "0926-9959",
publisher = "Wiley-Blackwell",
number = "10",

}

de Vries, HJC, de Barbeyrac, B, de Vrieze, NHN, Viset, JD, White, JA, Vall-Mayans, M & Unemo, M 2019, '2019 European guideline on the management of lymphogranuloma venereum' JEADV. Journal of the European Academy of Dermatology and Venereology, vol. 33, no. 10, pp. 1821-1828. https://doi.org/10.1111/jdv.15729

2019 European guideline on the management of lymphogranuloma venereum. / de Vries, H. J. C.; de Barbeyrac, B.; de Vrieze, N. H. N.; Viset, J. D.; White, J. A.; Vall-Mayans, M.; Unemo, M.

In: JEADV. Journal of the European Academy of Dermatology and Venereology, Vol. 33, No. 10, 2019, p. 1821-1828.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - 2019 European guideline on the management of lymphogranuloma venereum

AU - de Vries, H. J. C.

AU - de Barbeyrac, B.

AU - de Vrieze, N. H. N.

AU - Viset, J. D.

AU - White, J. A.

AU - Vall-Mayans, M.

AU - Unemo, M.

PY - 2019

Y1 - 2019

N2 - New or important issues in this updated version of the 2013 European guideline on the management of lymphogranuloma venereum (LGV): EPIDEMIOLOGY: Lymphogranuloma venereum continues to be endemic among European men who have sex with men (MSM) since 2003. Lymphogranuloma venereum infections in heterosexuals are extremely rare in Europe, and there is no evidence of transmission of LGV in the European heterosexual population. AETIOLOGY AND TRANSMISSION: Chlamydia trachomatis serovars/genovars L2b and L2 are the causative strains in the majority of cases in Europe. CLINICAL FEATURES: Among MSM, about 25% of the anorectal LGV infections are asymptomatic. Genital infections among MSM are rare; the ratio of genital vs. anorectal LGV infections is 1 in 15. DIAGNOSIS: To diagnose LGV, a sample tested C. trachomatis positive with a commercial nucleic acid amplification test (NAAT) platform should be confirmed with an LGV discriminatory NAAT. TREATMENT: Doxycycline 100 mg twice a day orally for 21 days is the recommended treatment for LGV. This same treatment is recommended also in asymptomatic patients and contacts of LGV patients. If another regimen is used, a test of cure (TOC) must be performed.

AB - New or important issues in this updated version of the 2013 European guideline on the management of lymphogranuloma venereum (LGV): EPIDEMIOLOGY: Lymphogranuloma venereum continues to be endemic among European men who have sex with men (MSM) since 2003. Lymphogranuloma venereum infections in heterosexuals are extremely rare in Europe, and there is no evidence of transmission of LGV in the European heterosexual population. AETIOLOGY AND TRANSMISSION: Chlamydia trachomatis serovars/genovars L2b and L2 are the causative strains in the majority of cases in Europe. CLINICAL FEATURES: Among MSM, about 25% of the anorectal LGV infections are asymptomatic. Genital infections among MSM are rare; the ratio of genital vs. anorectal LGV infections is 1 in 15. DIAGNOSIS: To diagnose LGV, a sample tested C. trachomatis positive with a commercial nucleic acid amplification test (NAAT) platform should be confirmed with an LGV discriminatory NAAT. TREATMENT: Doxycycline 100 mg twice a day orally for 21 days is the recommended treatment for LGV. This same treatment is recommended also in asymptomatic patients and contacts of LGV patients. If another regimen is used, a test of cure (TOC) must be performed.

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85073306839&origin=inward

UR - https://www.ncbi.nlm.nih.gov/pubmed/31243838

U2 - 10.1111/jdv.15729

DO - 10.1111/jdv.15729

M3 - Article

VL - 33

SP - 1821

EP - 1828

JO - JEADV. Journal of the European Academy of Dermatology and Venereology

JF - JEADV. Journal of the European Academy of Dermatology and Venereology

SN - 0926-9959

IS - 10

ER -