3D power Doppler in uterine fibroids; influence of gain, cardiac cycle and off-line measurement techniques

L. L. Nieuwenhuis*, W. J.K. Hehenkamp, H. A.M. Brölmann, J. A.F. Huirne

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


This study answers the question of whether ultrasound machine settings and the cardiac cycle can influence 3D power Doppler (3D PD) indices in the evaluation of uterine fibroid vascularisation. These parameters were reported to affect the vascular indices and cause undesired variation. 3D PD ultrasound was performed using three different gain settings: a fixed predetermined gain (50 dB), a higher gain (65 dB) and an individualised subjectively most optimal gain. Two consecutive 3D PD sweeps were taken to evaluate the effect of the cardiac cycle. A predetermined most optimal fixed gain setting was not different from the individually most optimal chosen gain in vascular assessment of fibroids. A higher gain corresponded with a significantly higher vascular index (VI). Potential variation during the cardiac cycle does not disturb the VI in fibroids.

Original languageEnglish
Pages (from-to)103-109
Number of pages7
JournalJournal of Obstetrics and Gynaecology
Issue number1
Publication statusPublished - 2 Jan 2018

Cite this