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1989
11 Downloads (Pure)

Human pharmacokinetics of carboplatin after oral administration

Pinedo, H. M., van Hennik, M. B., van der Vijgh, W. J. F., Klein, I. & Vermorken, J. B., 1989, In : Cancer Chemotherapy and Pharmacology. 23, p. 126-127

Research output: Contribution to journalArticleAcademicpeer-review

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Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance

Jansen, G., Westerhof, G. R., Kathmann, I., Rademaker, B. C., Rijksen, G. & Schornagel, J. H., 1 May 1989, In : Cancer Research. 49, 9, p. 2455-9 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

12 Downloads (Pure)

Immunohistochemical detection and quantitation of p-glycoprotein in multiple drug-resistant human myeloma cells: association with level of drug resistance and drug accumulation

Dalton, W. S., Grogan, T. M., Rybski, J. A., Scheper, R. J., Richter, L., Kailey, J., Broxterman, H. J. & Pinedo, H. M., 1989, In : Blood. 73, 3, p. 747-752

Research output: Contribution to journalArticleAcademicpeer-review

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16 Downloads (Pure)

Immunohistochemical detection of P glycoprotein in human tumor cells with a low degree of drug resistance

Broxterman, H. J., Pinedo, H. M., Kuiper, C. M., van der Hoeven, J. M., de Lange, P., Quak, J. J., Scheper, R. J., Keizer, H. G., Schuurhuis, G. J. & Lankelma, J., 1989, In : International Journal of Cancer. 43, p. 340-343

Research output: Contribution to journalArticleAcademicpeer-review

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Improved detection of acute myocardial infarction by magnetic resonance imaging using Gadolinium-DTPA

van Dijkman, P. R. M., Doornbos, J., de Roos, A., van der Laarse, A., Postema, S., Matheijssen, N. A. A., Bruschke, A. V. G., Voorthuisen, A. E. V., Cats, V. M. & van der Wall, E. E., 1 Mar 1989, In : The International Journal of Cardiac Imaging. 5, 1, p. 1-8 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Influence of the mesocortical dopaminergic system on activity, food hoarding, social-agonistic behavior, and spatial delayed alternation in male rats

Stam, C. J., de Bruin, J. P., van Haelst, A. M., van der Gugten, J. & Kalsbeek, A., Feb 1989, In : Behavioral Neuroscience. 103, 1, p. 24-35 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interaction of N-hydroxy(sulfo) succinimide active esters with the reduced folate/methotrexate transport system from human leukemic CCRF-CEM cells

Jansen, G., Westerhof, G. R., Rijksen, G. & Schornagel, J. H., 3 Nov 1989, In : Biochimica et Biophysica Acta. Reviews on Cancer. 985, 3, p. 266-70 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interferon-gamma-increased adherence of lymphocytes to high endothelial venules

Hendriks, H. R., Korn, C., Mebius, R. E. & Kraal, G., Oct 1989, In : Immunology. 68, 2, p. 221-6 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

13 Downloads (Pure)

In vitro and in vivo inhibition of thymidylate synthase of human colon cancer by 5-fluorouracil

Peters, G. J., Laurensse, E., van Groeningen, C. J., Meijer, S. & Pinedo, H. M., 1989, In : Advances in Experimental Medicine and Biology. 253A, p. 439-445

Research output: Contribution to journalArticleAcademicpeer-review

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13 Downloads (Pure)

Lack of effectiveness of combined 5 fluorouracil and leucovorin in patients with 5 fluorouracil resistant advanced colorectal cancer

van Groeningen, C. J., Peters, G. & Pinedo, H. M., 1989, In : European Journal of Cancer and Clinical Oncology. 25, p. 45-49

Research output: Contribution to journalArticleAcademicpeer-review

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Matrix structure representation of a medical knowledge base

Kerkhof, P. L. M., 1 Dec 1989, p. 1832-1833. 2 p.

Research output: Contribution to conferencePaperAcademic

Medical applications of artificial intelligence and information systems.

Finkelstein, S. M., Kerkhof, P. L. & Okada, M., 1 May 1989, In : IEEE Transactions on Biomedical Engineering. 36, 5, p. 501-502 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Metastasis of prostate tumor cells to bronchus associated lymphoid tissue

Geldof, A. A. & Rao, B. R., 1 Jan 1989, In : In vivo. 3, 2, p. 87-91 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Mucocutaneous side effects of brequinar sodium

Schwartsmann, G., Bork, E., Vermorken, J. B., Nieboer, C., Dodion, P., ten Bokkel Huinink, W. W., Hansen, N., Armand, J. P., Winograd, B., Gall, H., Pinedo, H. M. & Seldenrijk, A., 1989, In : Cancer. 63, p. 243-248

Research output: Contribution to journalArticleAcademicpeer-review

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New anti-ischaemic drugs: cytoprotective action with no primary haemodynamic effects

Boddeke, E., Hugtenburg, J., Jap, W., Heynis, J. & Zwieten, P. V., 1 Jan 1989, In : Trends in Pharmacological Sciences. 10, 10, p. 397-400 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family

Evers, M. P., Zelle, B., Bebelman, J. P., van Beusechem, V., Kraakman, L., Hoffer, M. J., Pronk, J. C., Mager, W. H., Planta, R. J., Eriksson, A. W. & Frants, R., Apr 1989, In : Genomics. 4, 3, p. 232-9 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

OVULATION INDUCTION, IN-VITRO FERTILISATION, AND NEURAL TUBE DEFECTS

Cornel, M. C., Ten Kate, L. P. & Te Meerman, G. J., 30 Dec 1989, In : The Lancet. 334, 8678-8679, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

OVULATION INDUCTION AND NEURAL TUBE DEFECTS

Cornel, M. C., Ten Kate, L. P., Graham Dukes, M. N., de Jong-VD Berg, L. T. W., Meyboom, R. H. B., Garbis, H. & Peters, P. W. J., 17 Jun 1989, In : The Lancet. 333, 8651, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

Perimenopausal bone mass and risk factors

Elders, P. J. M., Netelenbos, J. C., Lips, P., Khoe, E., van Ginkel, F. C., Hulshof, K. F. A. M. & van der Stelt, P. F., 1989, In : Bone and Mineral. 7, 3, p. 289-299

Research output: Contribution to journalArticleAcademicpeer-review

15 Downloads (Pure)

Pharmacokinetics of Brequinar sodium (NSC 368390) in patients with solid tumors during a phase I study

Schwartsmann, G., van der Vijgh, W. J. F., van Hennik, M. B., Vermorken, J. B., Dodion, P., ten Bokkel Huinink, W. W., Joggi, G., Gall, H., Crespeigne, N., Simonetti, G., Winograd, B. & Pinedo, H. M., 1989, In : European Journal of Cancer and Clinical Oncology. 25, p. 1675-1682

Research output: Contribution to journalArticleAcademicpeer-review

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Preclinical chemotherapy on human head and neck cancer xenografts grown in athymic nude mice

Braakhuis, B. J. M., Van Dongen, G. A. M. S., Bagnay, M., Van Walsum, M. & Snow, G. B., 1 Jan 1989, In : Head & Neck. 11, 6, p. 511-515 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Protective activity of nifedipine and R 58735 upon damage caused by global ischemia in the guinea pig heart-lung preparation

Boddeke, H. W. G. M., Jap, T. J. W., Hugtenburg, J. G., Heynis, J. B., Veldsema-Currie, R. D., Wilffert, B. & van Zwieten, P. A., 1 Sep 1989, In : Basic Research in Cardiology. 84, 5, p. 489-498 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pulsatile luteinizing hormone release and ovarian steroid levels in female-to-male transsexuals compared to heterosexual women

Spinder, T., Spijkstra, J. J., Gooren, L. J. G. & Burger, C. W., 1 Jan 1989, In : Psychoneuroendocrinology. 14, 1-2, p. 97-102 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Quantitive determination of factors contributing to doxorubicin resistance in multidrug resistant cells

Schuurhuis, G. J., Broxterman, H. J., Cervantes, A., van Heijningen, H. M., de Lange, J. H. M., Baak, J. P. A., Pinedo, H. M. & Lankelma, J., 1989, In : Journal of the National Cancer Institute. 81, p. 1887-1892

Research output: Contribution to journalArticleAcademicpeer-review

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Reperfused and nonreperfused myocardial infarction: Diagnostic potential of Gd-DTPA-enhanced MR imaging

De Roos, A., Van Rossum, A. C., Van Der Wall, E., Postema, S., Doornbos, J., Matheijssen, N., Van Dijkman, P. R. M., Visser, F. C. & Van Voorthuisen, A. E., 1 Jan 1989, In : Radiology. 172, 3, p. 717-720 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Restricted usefulness of tetraethylammonium and 4-aminopyridine for the characterization of receptor-operated K+-channels

Drukarch, B., Kits, K. S., Leysen, J. E., Schepens, E. & Stoof, J. C., Sep 1989, In : British Journal of Pharmacology. 98, 1, p. 113-8 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

12 Downloads (Pure)

Reversal of 5-fluorouracil-induced myelosuppression by prolonged administration of high-dose uridine

van Groeningen, C. J., Peters, G. J., Leyva, A., Laurensse, E. J. & Pinedo, H. M., 1989, In : Journal of the National Cancer Institute. 81, p. 157-162

Research output: Contribution to journalArticleAcademicpeer-review

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Selective effects of [D-Ser2(O-t-butyl),Leu5]enkephalyl-Thr6 and [D-Ser2(O-t-butyl),Leu5]enkephalyl-Thr6 (O-t-butyl), two new enkephalin analogues, on neurotransmitter release and adenylate cyclase in rat brain slices

De Vries, T. J., Schoffelmeer, A. N. M., Delay-Goyet, P., Roques, B. P. & Mulder, A. H., 7 Nov 1989, In : European Journal of Pharmacology. 170, 3, p. 137-143 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Somatic cell gene therapy: the model of adenosine deaminase deficiency

Van Beusechem, V. W., Kukler, A., Bakx, T. A. & Valerio, D., Dec 1989, In : Bone Marrow Transplantation. 4 Suppl 4, p. 133-6 4 p.

Research output: Contribution to journalReview articleAcademic

Stimulation of D-2 dopamine receptors decreases the evoked in vitro release of [3H]acetylcholine from rat neostriatum: role of K+ and Ca2+

Drukarch, B., Schepens, E., Schoffelmeer, A. N. & Stoof, J. C., Jun 1989, In : Journal of Neurochemistry. 52, 6, p. 1680-5 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Downloads (Pure)

TCdNU (LS2667), a new active drug in the treatment of advanced colorectal cancer

Gundersen, S., Dombernowsky, P., Cavalli, F., Bruntsch, U., Renard, J., van Glabbeke, M. & Pinedo, H. M., 1989, In : European Journal of Cancer and Clinical Oncology. 25, 7, p. 1095-1099

Research output: Contribution to journalArticleAcademicpeer-review

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21 Downloads (Pure)

Ten-year survival and late sequelae in testicular cancer patients treated with cisplatin, vinblastine and bleomycin

Stoter, G., Koopman, A., Vendrik, C. P. J., Struyvenberg, A., Sleyfer, D. T., Willemse, P. H. B., Schraffordt Koops, H., van Oosterom, A. T., ten Bokkel Huinink, W. W. & Pinedo, H. M., 1989, In : Journal of Clinical Oncology. 7, p. 1099-1104

Research output: Contribution to journalArticleAcademicpeer-review

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The differential effect of calcium antagonists on the positive inotropic effects induced by calcium and monensin in cardiac preparations of rats and guinea-pigs

Hugtenburg, J. G., Mathy, M. J., Beckeringh, J. J. & van Zwieten, P. A., 1 Jan 1989, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 340, 5, p. 558-566 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The drinker or the drink? The concept of alcoholism in the 19th and 20th century

Widdershoven, G. A. M. & Ter Meulen, R. H. J., 1 Jan 1989, In : Tijdschrift voor Alcohol, Drugs en Andere Psychotrope Stoffen. 15, 3, p. 105-112 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The effects of long term testosterone administration on pulsatile luteinizing hormone secretion and on ovarian histology in eugonadal female to male transsexual subjects

Spinder, T., Spijkstra, J. J., Van Den Tweel, J. G., Burger, C. W., Van Kessel, H., Hompes, P. G. A. & Gooren, L. J. G., 1 Jan 1989, In : Journal of Clinical Endocrinology and Metabolism. 69, 1, p. 151-157 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

The heterogeneity of the reticulum of rat peripheral lymphoid organs identified by monoclonal antibodies

Van den Berg, T. K., Döpp, E. A., Brevé, J. J., Kraal, G. & Dijkstra, C. D., Sep 1989, In : European Journal of Immunology. 19, 9, p. 1747-56 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

The new headache classification

Couturier, E. G. M., Ansink, B. J. J. & Clifford, R. F., 1 Dec 1989, In : New Trends in Clinical Neuropharmacology. 3, 4, p. 203-205 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

15 Downloads (Pure)

The relation between inhibition of cell growth and of dihydroorotic acid dehydrogenase by brequinar sodium

de Kant, E., Pinedo, H. M., Laurensse, E. & Peters, G. J., 1989, In : Cancer Letters. 46, p. 123-127

Research output: Contribution to journalArticleAcademicpeer-review

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The relationship between dihydroorotic acid dehydrogenase and in vitro and in vivo cytostatic effects of Brequinar (DUP-785; NSC 368390)

Peters, G. J., Laurensse, E., de Kant, E., Nadal, J. C. & Pinedo, H. M., 1989, In : Advances in Experimental Medicine and Biology. 253B, p. 375-382

Research output: Contribution to journalArticleAcademicpeer-review

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Transplantability of Human Head and Neck Squamous Cell Carcinomas in Athymic Nude Mice

Braakhuis, B. J. M., Laarman, D. A. W., Nauta, J. J. P., Van Walsum, M., Van Dongen, G. A. M. S. & Snow, G. B., 1 Jan 1989, In : Archives of Otolaryngology--Head and Neck Surgery. 115, 9, p. 1076-1078 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Vertebral bone density in children: effect of puberty.

van Kuijk, C., Mar 1989, In : Radiology. 170, 3 Pt 1, p. 895-896 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin K-dependent carboxylase: Affinity purification from bovine liver by using a synthetic propeptide containing the γ-carboxylation recognition site

Hubbard, B. R., Ulrich, M. M. W., Jacobs, M., Vermeer, C., Walsh, C., Furie, B. & Furie, B. C., 1 Jan 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 18, p. 6893-6897 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Vitamin K-dependent carboxylation. In vitro modification of synthetic peptides containing the γ-carboxylation recognition site

Hubbard, B. R., Jacobs, M., Ulrich, M. M. W., Walsh, C., Furie, B. C. & Furie, B. C., 1 Jan 1989, In : Journal of Biological Chemistry. 264, 24, p. 14145-14150 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

What is a safe heat dose which can be applied to normal brain tissue?

Sminia, P., Haveman, J. & Ongerboer de Visser, B. W., 1 Jan 1989, In : International journal of hyperthermia. 5, 1, p. 115-7 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

1990

A 22-kd surface antigen detected by monoclonal antibody E 48 is exclusively expressed in stratified squamous and transitional epithelia

Quak, J. J., Balm, A. J. M., Van Dongen, G. A. M. S., Brakkee, J. G. P., Scheper, R. J., Snow, G. B. & Meijer, C. J. L. M., 1 Jan 1990, In : American Journal of Pathology. 136, 1, p. 191-197 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

AANWIJZINGEN VOOR EEN VERHOOGDE KANS OP DEFECTEN VAN DE NEURALE BUIS BIJ ZWANGERSCHAPPEN ONTSTAAN NA OVULATIE-INDUCTIE EN (OF) IN VITRO-FERTILISATIE

Cornel, M. C., De Jong-Van den Berg, L. T. W., Koudstaal, J., Wiegerinck, M. A. H. M., Te Meerman, G. J. & Ten Kate, L. P., 1 Jan 1990, In : Nederlands Tijdschrift voor Geneeskunde. 134, 28, p. 1357-1361 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

AANWIJZINGEN VOOR EEN VERHOOGDE KANS OP DEFECTEN VAN DE NEURALE BUIS BIJ ZWANGERSCHAPPEN ONTSTAAN NA OVULATIE-INDUCTIE EN (OF) IN VITRO-FERTILISATIE (I: Reply)

Cornel, M. C., De Jong-Van den Berg, L. T., Koudstaal, J., Wiegerinck, M. A., Te Meerman, G. J. & Ten Kate, L. P., 12 Sep 1990, In : Nederlands Tijdschrift voor Geneeskunde. 134, 35, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

Activation of the complement system by high dose immunotherapy with recombinant IL 2: Relation to the development of side effects

Thijs, L. G., Hack, C. E., Strack van Schijndel, R. J. M., Nuijens, J. H., Wolbin, G. J., Eerenberg-Belmer, A. J. M., van der Valk, H., Wagstaff, J. & Pinedo, H. M., 1990, In : The Journal of Immunology. 144, p. 2419-2424

Research output: Contribution to journalArticleAcademicpeer-review

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10 Downloads (Pure)

Activity of GR30921X (NSC 382057) and GR63178A (NSC D611615) in human ovarian cancer lines

Boven, E., Erkelens, C. A., Luning, M. & Pinedo, H. M., 1990, In : British Journal of Cancer. 61, 5, p. 709-711

Research output: Contribution to journalArticleAcademicpeer-review

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An alcoholic with pleural effusion

Girbes, A. R. J., Postmus, P. E., Jansen, W., Jagt, V. D. E. J. & Kleibeuker, J. H., 1 Dec 1990, In : European Respiratory Journal. 3, 8, p. 934-936 3 p.

Research output: Contribution to journalArticleAcademicpeer-review