Find Research Outputs

1990

Interobserver variation in histopathological grading of cervical dysplasia

de Vet, H. C. W., Knipschild, P. G., Schouten, H. J. A., Koudstaal, J., Kwee, W. S., Willebrand, D., Sturmans, F. & Arends, J. W., 1 Jan 1990, In : Journal of Clinical Epidemiology. 43, 12, p. 1395-1398 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

In vitro models of cardiac ischaemia and the evaluation of the cardioprotective effects of calcium antagonists and other anti-ischaemic drugs

Hugtenburg, J. G., Beckeringh, J. J., Boddeke, H. W. G. M., Heijnis, J. B., Jap, T. J. W., Mathy, M. J. & Van Zwieten, P. A., 1 Jan 1990, In : Progress in Pharmacology and Clinical Pharmacology. 8, 2, p. 19-35 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

5 Downloads (Pure)

In vivo inhibition of the pyrimidine de novo enzyme dihydrorotic acid dehydrogenase by brequinar sodium (DUP-785; NSC 368390) in mice and patients

Peters, G. J., Schwartsmann, G., Nadal, J. C., Laurensse, E. J., van Groeningen, C. J. & Pinedo, H. M., 1990, In : Cancer Research. 50, p. 4644-4649

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Islet-amyloid polypeptide in human plasma

Van Jaarsveld, B. C., Hackeng, W. H. L., Nieuwenhuis, M. G., Erkelens, D. W., Geerdink, R. A. & Lips, C. J. M., 6 Jan 1990, In : The Lancet. 335, 8680, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

6 Downloads (Pure)

Isolated mouse atrium as a model to study anthracycline cardiotoxicity. The role of the beta-adrenoceptor system and reactive oxygen species

de Jong, J., Schoofs, P. R., Onderwater, R. C. A., van der Vijgh, W. J. F., Pinedo, H. M. & Bast, A., 1990, In : Research Communications in Chemical Pathology and Pharmacology. 68, p. 275-289

Research output: Contribution to journalArticleAcademicpeer-review

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Lack of a dopamine autoreceptor selective profile of B-HT 920 in functional in vitro model systems of D2 receptors in rat striatum

Drukarch, B., Schepens, E., Dolleman-Van der Weel, M. J., De Boer, P., Van Vliet, B. J. & Stoof, J. C., 9 Oct 1990, In : European Journal of Pharmacology. 187, 2, p. 257-69 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lack of effect of lithium on the renal response to DA1‐dopamine receptor stimulation by fenoldopam in normal man [see comments]

Girbes, AR., Smit, AJ., Meijer, S. & Reitsma, WD., 1 Jan 1990, In : British Journal of Clinical Pharmacology. 29, 4, p. 413-415 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lithium and the renal response to gludopa, fenoldopam and dopamine [letter; comment]

Girbes, AR., Smit, AJ., Meijer, S. & Reitsma, WD., 1 Jan 1990, In : British Journal of Clinical Pharmacology. 30, 4, p. 652-653 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Macrophages and the activity of high endothelial venules. The effect of interferon-gamma

Mebius, R. E., Hendriks, H. R., Brevé, J. & Kraal, G., Jul 1990, In : European Journal of Immunology. 20, 7, p. 1615-8 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Massive pleural effusion due to pancreatic pseudocyst

Girbes, A. R. J., Postmus, P. E., Jansen, W., Jagt, V. D. E. J. & Kleibeuker, J. H., 1 Jan 1990, In : Thorax. 45, 7, p. 563-564 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Mechanisms underlying methotrexate inactivity in human head and neck cancer xenografts

Braakhuis, BJM., van Dongen, G., Snow, G. B., Peters, GJ., Leyva, A. & Jansen, G., 1990, In: "Chemistry and Biology of Pteridines". Curtius, H. C., Ghisla, S. & Blau, N. (eds.). Walter de Gruyter, p. 1119-1122 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

Medical language and knowledge base systems

Kerkhof, P. L. M., 1 Dec 1990, Biomedical Engineering Perspectives: Health Care Technologies for the 1990's and Beyond. pt 3 ed. Publ by IEEE, p. 1320-1321 2 p. (Proceedings of the Annual Conference on Engineering in Medicine and Biology; no. pt 3).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Membrane transport characteristics of the thymidylate synthase inhibitor 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid

Jansen, G., Schornagel, J. H., Westerhof, G. R., Rijksen, G., Newell, D. R. & Jackman, A. L., 1990, In: "Chemistry and Biology of Pteridines". Curtius, H. C., Gishla, S. & Blau, N. (eds.). Walter de Gruyter, p. 1056-1059 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

Methotrexate (MTX) transport and cytotoxicity of MTX and trimetrexate (TMQ) for human squamous cell carcinoma (SCC) of the head and neck grown at low folate concentrations

van der Laan, B. F. A. M., Hordijk, G. J., Jansen, G., van Gestel, J. A., Kathmann, G. A. M., Westerhof, G. R., Schornagel, J. H. & Rijksen, G., 1990, In: "Chemistry and Biology of Pteridines". Walter de Gruyter, p. 1127-1130 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates

Jansen, G., Westerhof, G. R., Jarmuszewski, M. J., Kathmann, I., Rijksen, G. & Schornagel, J. H., 25 Oct 1990, In : Journal of Biological Chemistry. 265, 30, p. 18272-7 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors

Jansen, G., Schornagel, J. H., Westerhof, G. R., Rijksen, G., Newell, D. R. & Jackman, A. L., 1 Dec 1990, In : Cancer Research. 50, 23, p. 7544-8 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

mu-opioid receptor-mediated inhibition of beta-adrenergic sensitive adenylate cyclase in primary cultures of rat neostriatal neurons

Drukarch, B., 1990, new leads in opioid research, excerpta medica international congress series vol. 914. Excerpta Medica, Vol. 914. p. 253-255

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Muscarinic receptor activation attenuates D2 dopamine receptor mediated inhibition of acetylcholine release in rat striatum: indications for a common signal transduction pathway

Drukarch, B., Schepens, E. & Stoof, J. C., 1990, In : Neuroscience. 37, 1, p. 1-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Myocardial infarct size after reperfusion therapy: Assessment with Gd-DTPA-enhanced MR imaging

De Roos, A., Matheijssen, N. A. A., Doornbos, J., Van Dijkman, P. R. M., Van Voorthuisen, A. E. & Van Der Wall, E. E., 1 Jan 1990, In : Radiology. 176, 2, p. 517-521 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

On the mode of action of LFA-1

Figdor, C. G., van Kooyk, Y. & Keizer, G. D., Aug 1990, In : Immunology today. 11, 8, p. 277-80 4 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Ontogeny of opioid receptors mediating inhibition of adenylate cyclase activity and neurotransmitter release in rat brain

De Vries, T. J., Hogenboom, F., Mulder, A. H. & Schoffelmeer, A. N. M., 1 Jan 1990, In : European Journal of Pharmacology. 183, 6, p. 2305-2306 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Ontogeny of μ-, δ- and κ-opioid receptors mediating inhibition of neurotransmitter release and adenylate cyclase activity in rat brain

De Vries, T. J., Hogenboom, F., Mulder, A. H. & Schoffelmeer, A. N. M., 1 Jun 1990, In : DEVELOPMENTAL BRAIN RESEARCH. 54, 1, p. 63-69 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Perceived parental rearing style, parental divorce and transsexualism: A controlled study

Cohen-Kettenis, P. T. & Arrindell, W. A., 1 Jan 1990, In : Psychological Medicine. 20, 3, p. 613-620 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

23 Downloads (Pure)

Phase I study of Brequinar sodium (NSC368390) in patients with solid malignancies

Schwartsmann, G., Dodion, P., Vermorken, J. B., ten Bokkel Huinink, W. W., Joggi, J., Winograd, B., Gall, H., Simonetti, G., van der Vijgh, W. J. F., van Hennik, M. B., Crespeigne, N. & Pinedo, H. M., 1990, In : Cancer Chemotherapy and Pharmacology. 25, p. 345-351

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Prediction of fetal anemia by measurement of the mean blood velocity in the fetal aorta

Nicolaides, K. H., Bilardo, C. M. & Campbell, S., 1990, In : American Journal of Obstetrics and Gynecology. 162, 1, p. 209-212

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence of lethal osteochondrodysplasias

Cobben, J. M., Cornel, M. C., Dijkstra, I. & Ten Kate, L. P., 4 Jul 1990, In : American Journal of Medical Genetics. 36, 3, p. 377-378 2 p.

Research output: Contribution to journalLetterAcademicpeer-review

Production of a monoclonal antibody (K 931) to a squamous cell carcinoma associated antigen identified as the 17-1A antigen

Quak, J. J., Van Dongen, G., Brakkee, J. G. P., Hayashida, D. J., Balm, A. J. M., Snow, G. B. & Meijer, C. J. L. M., 1 Jan 1990, In : Hybridoma. 9, 4, p. 377-387 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Production of Monoclonal Antibodies to Squamous Cell Carcinoma Antigens

Quak, J. J., Balm, F. J. M., Brakkee, J. G. P., Scheper, R. J., Meijer, C. J. L. M. & Snow, G. B., 1 Jan 1990, In : Archives of Otolaryngology--Head and Neck Surgery. 116, 2, p. 181-185 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prostatic tumor (R3327) skeletal metastasis

Geldof, A. A. & Rao, B. R., 1 Jan 1990, In : The Prostate. 16, 4, p. 279-290 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Purification and characterization of a membrane associated folate binding protein from human CCRF-CEM cells

Westerhof, G. R., Jansen, G., Kathmann, G. A. M., Schornagel, J. H. & Rijksen, G., 1990, In: "Chemistry and Biology of Pteridines: Pteridines and Folic Acid Derivatives". Curtius, H. C., Ghisla, S. & Blau, N. (eds.). Walter de Gruyter, p. 624-627 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

Regional cerebral blood flow (rCBF) during migraine using 99m Tc-hexamethylpropyleneamineoxime ( 99m Tc-HMPAO) and single photon emission tomography (SPET)

Couturier, E. G. M., Davies, P. T. G., Steiner, T. J., Costa, D. C., Jones, B. E., Jewkes, R. F. & Rose, F. C., 1 Dec 1990, In : Clinical Neurology and Neurosurgery. 92, 2, 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Renal and endocrine effects of fenoldopam and metoclopramide in normal man

Girbes, A. R. J., Smit, A. J., Meijer, S. & Reitsma, W. D., 1 Jan 1990, In : Nephron. 56, 2, p. 179-185 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

21 Downloads (Pure)

Retention of in vivo antipyrimidine effects of brequinar sodium (DUP-785;NSC 368390) in murine liver, bone marrow and colon cancer

Peters, G. J., Nadal, J. C., Laurensse, E., de Kant, E. & Pinedo, H. M., 1990, In : Biochemical Pharmacology. 39, p. 135-144

Research output: Contribution to journalArticleAcademicpeer-review

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6 Downloads (Pure)

Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded X174 DNA

Mans, D. R. A., Retèl, J., van Maanen, J. M. S., Lafleur, M. V. M., van Schaik, M. A., Pinedo, H. M. & Lankelma, J., 1990, In : British Journal of Cancer. 62, p. 54-60

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Specific killing of cytotoxic T cells and antigen-presenting cells by CD4+ cytotoxic T cell clones a novel potentially immunoregulatory T-T cell interaction in man

Ottenhoff, T. H. M. & Mutis, T., 1 Jun 1990, In : Journal of Experimental Medicine. 171, 6, p. 2011-2024 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Successful fibrinolytic therapy for massive pulmonary embolism during pregnancy

Oudemans-van Straaten, H. M., Stoutenbeek, C. P., Van Der Lans, S. & Schutte, M. F., 1 Jan 1990, In : Clinical Intensive Care. 1, 2, p. 77-79 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Susceptibility in relation to the development of decubitus

Ribbe, M. W., Meijer, J. H., Germs, P. & Van Marum, R. J., 1 Dec 1990, In : Vox Hospitii. 14, 4, p. 12-17 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

The cardioprotective effect of nifedipine, verapamil and diltiazem in relationship to their vasodilatory activity in isolated rat hearts

Hugtenburg, J. G., Mathy, J. J., Beckeringh, J. J. & Van Zwieten, P. A., 1 Jan 1990, In : European Journal of Pharmacology. 183, 3, p. 793-794 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

The function of high endothelial venules in mouse lymph nodes stimulated by oxazolone

Mebius, R. E., Brevé, J., Duijvestijn, A. M. & Kraal, G., Nov 1990, In : Immunology. 71, 3, p. 423-7 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

The influence of nifedipine and mioflazine on mitochondrial calcium overload in normoxic and ischaemic guinea-pig hearts

Hugtenburg, J. G., Van Voorst, M. J. D., Van Marle, J., Mathy, M. J., Beckeringh, J. J., Van Veen, H. A., Hendriks, M. G. C. & Van Zwieten, P. A., 13 Mar 1990, In : European Journal of Pharmacology. 178, 1, p. 71-78 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Downloads (Pure)

The polyoxythelene castor oil Cremophor EL modifies multidrug resistance

Schuurhuis, G. J., Broxterman, H. J., Pinedo, H. M., van Heijningen, T. H. M., van Kalken, C. K., Vermorken, J. B., Spoelstra, E. C. & Lankelma, J., 1990, In : British Journal of Cancer. 62, p. 591-594

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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The prevalence of neglect: superiority of neuropsychological over clinical methods of estimation

Stam, C. J. & Bakker, M., 1990, In : Clinical Neurology and Neurosurgery. 92, 3, p. 229-35 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

The quadrupole coupling tensor of 95Mo in mesitylene molybdenum tricarbonyl

Huis, L., Pouwels, P. J. & Maclean, C., 1 Jan 1990, In : Molecular Physics. 70, 5, p. 879-889 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Thermotolerance of the spinal cord after fractionated hyperthermia applied to the rat in the cervical region

Sminia, P., Haveman, J. & Troost, D., 1 Mar 1990, In : International journal of hyperthermia. 6, 2, p. 269-78 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Three sensitive methods for the detection of cytomegalovirus in lung tissue of patients with interstitial pneumonitis

Jiwa, M., Steenbergen, RDM., Zwaan, F. E., Kluin, P. M., Raap, AK. & Ploeg van der, M., 1 Apr 1990, In : American Journal of Clinical Pathology. 93, 4, p. 491 494 p.

Research output: Contribution to journalArticleAcademicpeer-review

Triggering of the CD44 antigen on T lymphocytes promotes T cell adhesion through the LFA-1 pathway

Koopman, G., van Kooyk, Y., de Graaff, M., Meyer, C. J., Figdor, C. G. & Pals, S. T., 1 Dec 1990, In : Journal of Immunology. 145, 11, p. 3589-93 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tumor cell sensitivity and resistance to folate analogs: the role of carrier- and receptor-mediated transport systems

Jansen, G. & Schornagel, J. H., 1990, In: "Chemistry and Biology of Pteridines". Curtius, H. C., Ghisla, S. & Blau, N. (eds.). Walter de Gruyter, p. 1247-1252 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

1991

1ST CLINICAL-STUDY OF THE SELECTIVE 5-HT(3) ANTAGONIST, GRANISETRON (BRL-43694), IN THE ACUTE TREATMENT OF MIGRAINE HEADACHE

COUTURIER, EGM., HERING, R., FOSTER, CA., STEINER, TJ. & ROSE, FC., May 1991, In : Headache. 31, 5, p. 296-297

Research output: Contribution to journalArticleAcademicpeer-review

Accuracy in tangential breast treatment set-up: a portal imaging study

van Tienhoven, G., Lanson, J. H., Crabeels, D., Heukelom, S. & Mijnheer, B. J., 1 Jan 1991, In : Radiotherapy and Oncology. 22, 4, p. 317-322 6 p.

Research output: Contribution to journalArticleAcademicpeer-review