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2018

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

23andMe Research team, 2018, In : Nature Genetics. 50, 8, p. 1112-1121

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gene editing, NIPT

Cornel, M. C., Oct 2018, In : European Journal of Human Genetics. 26, p. 29-30

Research output: Contribution to journalMeeting AbstractAcademic

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

Dijkstra, K. K., Cattaneo, C. M., Weeber, F., Chalabi, M., van de Haar, J., Fanchi, L. F., Slagter, M., van der Velden, D. L., Kaing, S., Kelderman, S., van Rooij, N., van Leerdam, M. E., Depla, A., Smit, E. F., Hartemink, K. J., de Groot, R., Wolkers, M. C., Sachs, N., Snaebjornsson, P., Monkhorst, K. & 4 others, Haanen, J., Clevers, H., Schumacher, T. N. & Voest, E. E., 6 Sep 2018, In : Cell. 174, 6, p. 1586-1598.e12

Research output: Contribution to journalArticleAcademicpeer-review

Generation of universal "off-the-shelf'' chimeric antigen receptor (CAR)-engineered T cells

Prins, H. J., Katsarou, A., Shahrabi, A., Zweegman, S., Mutis, T. & Themeli, M., 1 Dec 2018, In : Human Gene Therapy. 29, 12, p. A120-A120

Research output: Contribution to journalMeeting AbstractAcademic

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

International Genomics of Alzheimer's Project (IGAP), 2018, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 10, p. 595-598 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetically isolated populations: Implications for genetic care

Matthijssen, I. B., 2018, 242 p.

Research output: ThesisResearch external, graduation external

Open Access

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, 2018, In : Nature Genetics. 50, 10, p. 1412-1425

Research output: Contribution to journalArticleAcademicpeer-review

Genetic and environmental influences on conduct and antisocial personality problems in childhood, adolescence, and adulthood

Wesseldijk, L. W., Bartels, M., Vink, J. M., van Beijsterveldt, C. E. M., Ligthart, L., Boomsma, D. I. & Middeldorp, C. M., 2018, In : European Child and Adolescent Psychiatry. 27, 9, p. 1123-1132

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis

Müller, T., Alberts, R., de Vries, E. M. G., Goode, E. C., Jiang, X., Sampaziotis, F., Rombouts, K., Böttcher, K., Folseraas, T., Weismüller, T. J., Mason, A. L., Wang, W., Alexander, G., Alvaro, D., Bergquist, A., Björkström, N. K., Beuers, U., Björnsson, E., Boberg, K. M., Bowlus, C. L. & 54 others, Bragazzi, M. C., Carbone, M., Chazouillères, O., Cheung, A., Dalekos, G., Eaton, J., Eksteen, B., Ellinghaus, D., Färkkilä, M., Festen, E. A. M., Floreani, A., Franceschet, I., Gotthardt, D. N., Hirschfield, G. M., Hoek, B. V., Holm, K., Hohenester, S., Hov, J. R., Imhann, F., Invernizzi, P., Juran, B. D., Lenzen, H., Lieb, W., Liu, J. Z., Marschall, H-U., Marzioni, M., Melum, E., Milkiewicz, P., Pares, A., Rupp, C., Rust, C., Sandford, R. N., Schramm, C., Schreiber, S., Schrumpf, E., Silverberg, M. S., Srivastava, B., Sterneck, M., Teufel, A., Vallier, L., Verheij, J., Vila, A. V., de Vries, B., Zachou, K., Chapman, R. W., Manns, M. P., Pinzani, M., Rushbrook, S. M., Lazaridis, K. N., Franke, A., Anderson, C. A., Karlsen, T. H., Ponsioen, C. Y. & Weersma, R. K., 2018, In : Gut. 67, 8, p. 1517-1524

Research output: Contribution to journalArticleAcademicpeer-review

Genetic Association of Lipids and Lipid Drug Targets With Abdominal Aortic Aneurysm: A Meta-analysis

Harrison, S. C., Holmes, M. V., Burgess, S., Asselbergs, F. W., Jones, G. T., Baas, A. F., van 't Hof, F. N., de Bakker, P. I. W., Blankensteijn, J. D., Powell, J. T., Saratzis, A., de Borst, G. J., Swerdlow, D. I., van der Graaf, Y., van Rij, A. M., Carey, D. J., Elmore, J. R., Tromp, G., Kuivaniemi, H., Sayers, R. D. & 3 others, Samani, N. J., Bown, M. J. & Humphries, S. E., 1 Jan 2018, In : JAMA cardiology. 3, 1, p. 26-33 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic basis of human congenital anomalies of the kidney and urinary tract

Sanna-Cherchi, S., Westland, R., Ghiggeri, G. M. & Gharavi, A. G., 2018, In : Journal of Clinical Investigation. 128, 1, p. 4-15

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Genetic correlation of antisocial behaviour with alcohol, nicotine, and cannabis use

Tielbeek, J. J., Vink, J. M., Polderman, T. J. C., Popma, A., Posthuma, D. & Verweij, K. J. H., 2018, In : Drug and Alcohol Dependence. 187, p. 296-299

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data

23 and Me Research Team, Oct 2018, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 177, 7, p. 641-657 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic defects disrupting glial ion and water homeostasis in the brain

Min, R. & van der Knaap, M. S., May 2018, In : Brain Pathology. 28, 3, p. 372-387 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic defects in mtDNA-encoded protein translation cause pediatric, mitochondrial cardiomyopathy with early-onset brain disease

Kamps, R., Szklarczyk, R., Theunissen, T. E., Hellebrekers, D. M. E. I., Sallevelt, S. C. E. H., Boesten, I. B., de Koning, B., van den Bosch, B. J., Salomons, G. S., Simas-Mendes, M., Verdijk, R., Schoonderwoerd, K., de Coo, I. F. M., Vanoevelen, J. M. & Smeets, H. J. M., 2018, In : European Journal of Human Genetics. 26, 4, p. 537-551

Research output: Contribution to journalArticleAcademicpeer-review

Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls - CORRIGENDUM

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Agrawal, A., Børglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H. J., Grove, J., Gelernter, J., Neale, B. M., Pardiñas, A. F., Stahl, E., Walters, J. T. R., Walters, R., Sullivan, P. F., Posthuma, D. & 1 others, Polderman, T. J. C., 2018, In : Psychological Medicine.

Research output: Contribution to journalErratumAcademicpeer-review

Genetic obesity: next-generation sequencing results of 1230 patients with obesity

Kleinendorst, L., Massink, M. P. G., Cooiman, M. I., Savas, M., van der Baan-Slootweg, O. H., Roelants, R. J., Janssen, I. C. M., Meijers-Heijboer, H. J., Knoers, N. V. A. M., Ploos van Amstel, H. K., van Rossum, E. F. C., van den Akker, E. L. T., van Haaften, G., van der Zwaag, B. & van Haelst, M. M., Sep 2018, In : Journal of Medical Genetics. 55, 9, p. 578-586 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genetic predisposition to infection in a case of atypical hemolytic uremic syndrome

Van Den Heuvel, L., Riesbeck, K., El Tahir, O., Gracchi, V., Kremlitzka, M., Morré, S. A., Van Furth, A. M., Singh, B., Okrój, M., Van De Kar, N., Blom, A. M. & Volokhina, E., 1 Jan 2018, In : Journal of human genetics. 63, 1, p. 93-96 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genetic profiling of poorly differentiated sinonasal tumours

López-Hernández, A., Vivanco, B., Franchi, A., Bloemena, E., Cabal, V. N., Potes, S., Riobello, C., García-Inclán, C., López, F., Llorente, J. L. & Hermsen, M., 5 Mar 2018, In : Scientific Reports. 8, 1, p. 3998

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic screening in two Iranian families with early-onset Alzheimer's disease identified a novel PSEN1 mutation

Wang, J-C., Alinaghi, S., Tafakhori, A., Sikora, E., Azcona, L. J., Karkheiran, S., Goate, A., Paisán-Ruiz, C. & Darvish, H., 2018, In : Neurobiology of Aging. 62, p. 244.e15-244.e17

Research output: Contribution to journalArticleAcademicpeer-review

Genetics of intellectual ability and disability: The importance of common variants and rare syndromes illustrated by studies of SNAP25 and AUTS2

Beunders, G., 2018, 160 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University Amsterdam

Genetic variant in CACNA1C is associated with PTSD in traumatized police officers /631/208/176/1988 /692/499 /45 /45/61 /45/23 article

Krzyzewska, I. M., Ensink, J. B. M., Nawijn, L., Mul, A. N., Koch, S. B., Venema, A., Shankar, V., Frijling, J. L., Veltman, D. J., Lindauer, R. J. L., Olff, M., Mannens, M. M. A. M., Van Zuiden, M. & Henneman, P., 1 Feb 2018, In : European Journal of Human Genetics. 26, 2, p. 247-257 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic variation in gonadal impairment in female survivors of childhood cancer: a PanCareLIFE study protocol

PanCareLIFE Consortium, 2018, In : BMC Cancer. 18, 1, p. 930

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic variation in the glucocorticoid receptor and psychopathology after dexamethasone administration in cardiac surgery patients

Kok, L., Hillegers, M. H., Veldhuijzen, D. S., Boks, M. P., Dieleman, J. M., van Dijk, D., Joëls, M. & Vinkers, C. H., Aug 2018, In : Journal of Psychiatric Research. 103, p. 167-172 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genetic variation of human neutrophil Fcγ receptors and SIRPα in antibody-dependent cellular cytotoxicity towards cancer cells

Treffers, L. W., Zhao, X. W., van der Heijden, J., Nagelkerke, S. Q., van Rees, D. J., Gonzalez, P., Geissler, J., Verkuijlen, P., van Houdt, M., de Boer, M., Kuijpers, T. W., van den Berg, T. K. & Matlung, H. L., Feb 2018, In : European Journal of Immunology. 48, 2, p. 344-354 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genetic vulnerability to DUSP22 promoter hypermethylation is involved in the relation between in utero famine exposure and schizophrenia

Boks, M. P., Houtepen, L. C., Xu, Z., He, Y., Ursini, G., Maihofer, A. X., Rajarajan, P., Yu, Q., Xu, H., Wu, Y., Wang, S., Shi, J. P., Hulshoff Pol, H. E., Strengman, E., Rutten, B. P. F., Jaffe, A. E., Kleinman, J. E., Baker, D. G., Hol, E. M., Akbarian, S. & 6 others, Nievergelt, C. M., De Witte, L. D., Vinkers, C. H., Weinberger, D. R., Yu, J. & Kahn, R. S., 21 Aug 2018, In : Schizophrenia Research. 4, 1, p. 16

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic vulnerability to schizophrenia is associated with cannabis use patterns during adolescence

Hiemstra, M., Nelemans, S. A., Branje, S., van Eijk, K. R., Hottenga, J-J., Vinkers, C. H., van Lier, P., Meeus, W. & Boks, M. P., 1 Sep 2018, In : Drug and Alcohol Dependence. 190, p. 143-150 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genital Chlamydia trachomatis and Neisseria gonorrhoeae infections among women in sub-Saharan Africa: A structured review

Ouburg, S., Jul 2018, In : International Journal of STD and AIDS. 29, 8, p. 806-824

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Lifelines Cohort Study, 2018, In : American journal of human genetics. 103, 5, p. 691-706

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Lifelines Cohort Study, 2018, In : Nature Communications. 9, 1, 4455.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide analysis of DNA methylation in buccal cells: A study of monozygotic twins and mQTLs

Van Dongen, J., Ehli, E. A., Jansen, R., Van Beijsterveldt, C. E. M., Willemsen, G., Hottenga, J. J., Kallsen, N. A., Peyton, S. A., Breeze, C. E., Kluft, C., Heijmans, B. T., Bartels, M., Davies, G. E. & Boomsma, D. I., 25 Sep 2018, In : Epigenetics and Chromatin. 11, 1, 54.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

eQTLGen Consortium, 1 Dec 2018, In : Nature Communications. 9, 1, 2941.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N. & 196 others, Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Giusti-Rodríguez, P., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hannon, E., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Hu, M., Hyde, C. L., Ising, M., Jansen, R., Jin, F., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lane, J. M., Li, Y., Li, Y., Lind, P. A., Liu, X., Lu, L., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, DI., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mill, J., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Purcell, S. M., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Saeed Mirza, S., Saxena, R., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. B. C., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Stockmeier, C. A., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Tian, C., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van Der Auwera, S., Van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., De Geus, E. C. J., Depaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Hinds, D. A., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. F. A., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O'Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Winslow, A. R., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D. & Sullivan, P. F., 1 May 2018, In : Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

CREAM Consortium, Jun 2018, In : Nature Genetics. 50, 6, p. 834-848 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

Savage, J. E., Jansen, P. R., Stringer, S., Watanabe, K., Bryois, J., De Leeuw, C. A., Nagel, M., Awasthi, S., Barr, P. B., Coleman, J. R. I., Grasby, K. L., Hammerschlag, A. R., Kaminski, J. A., Karlsson, R., Krapohl, E., Lam, M., Nygaard, M., Reynolds, C. A., Trampush, J. W., Young, H. & 97 others, Zabaneh, D., Hägg, S., Hansell, N. K., Karlsson, I. K., Linnarsson, S., Montgomery, G. W., Muñoz-Manchado, A. B., Quinlan, E. B., Schumann, G., Skene, N. G., Webb, B. T., White, T., Arking, D. E., Avramopoulos, D., Bilder, R. M., Bitsios, P., Burdick, K. E., Cannon, T. D., Chiba-Falek, O., Christoforou, A., Cirulli, E. T., Congdon, E., Corvin, A., Davies, G., Deary, I. J., Derosse, P., Dickinson, D., Djurovic, S., Donohoe, G., Conley, E. D., Eriksson, J. G., Espeseth, T., Freimer, N. A., Giakoumaki, S., Giegling, I., Gill, M., Glahn, D. C., Hariri, A. R., Hatzimanolis, A., Keller, M. C., Knowles, E., Koltai, D., Konte, B., Lahti, J., Le Hellard, S., Lencz, T., Liewald, D. C., London, E., Lundervold, A. J., Malhotra, A. K., Melle, I., Morris, D., Need, A. C., Ollier, W., Palotie, A., Payton, A., Pendleton, N., Poldrack, R. A., Räikkönen, K., Reinvang, I., Roussos, P., Rujescu, D., Sabb, F. W., Scult, M. A., Smeland, O. B., Smyrnis, N., Starr, J. M., Steen, V. M., Stefanis, N. C., Straub, R. E., Sundet, K., Tiemeier, H., Voineskos, A. N., Weinberger, D. R., Widen, E., Yu, J., Abecasis, G., Andreassen, O. A., Breen, G., Christiansen, L., Debrabant, B., Dick, D. M., Heinz, A., Hjerling-Leffler, J., Ikram, M. A., Kendler, K. S., Martin, N. G., Medland, S. E., Pedersen, N. L., Plomin, R., Polderman, T. J. C., Ripke, S., Van Der Sluis, S., Sullivan, P. F., Vrieze, S. I., Wright, M. J. & Posthuma, D., 1 Jul 2018, In : Nature Genetics. 50, 7, p. 912-919 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association meta-analysis of age at first cannabis use

Minică, C. C., Verweij, K. J. H., van der Most, P. J., Mbarek, H., Bernard, M., van Eijk, K. R., Lind, P. A., Liu, M. Z., Maciejewski, D. F., Palviainen, T., Sánchez-Mora, C., Sherva, R., Taylor, M., Walters, R. K., Abdellaoui, A., Bigdeli, T. B., Branje, S. J. T., Brown, S. A., Casas, M., Corley, R. P. & 31 others, Davey-Smith, G., Davies, G. E., Ehli, E. A., Farrer, L., Fedko, I. O., Garcia-Martínez, I., Gordon, S. D., Hartman, C. A., Heath, A. C., Hickie, I. B., Hickman, M., Hopfer, C. J., Hottenga, J. J., Kahn, R. S., Kaprio, J., Korhonen, T., Kranzler, H. R., Krauter, K., van Lier, P. A. C., Madden, P. A. F., Medland, S. E., Neale, M. C., Meeus, W. H. J., Montgomery, G. W., Nolte, I. M., Oldehinkel, A. J., Pausova, Z., Ramos-Quiroga, J. A., Richarte, V., Rose, R. J. & Cannabis Consortium, Nov 2018, In : Addiction. 113, 11, november, p. 2073-2086 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

Jiang, X., O'Reilly, P. F., Aschard, H., Hsu, Y. H., Richards, J. B., Dupuis, J., Ingelsson, E., Karasik, D., Pilz, S., Berry, DI., Kestenbaum, B., Zheng, J., Luan, J., Sofianopoulou, E., Streeten, E. A., Albanes, D., Lutsey, P. L., Yao, L., Tang, W., Econs, M. J. & 84 others, Wallaschofski, H., Völzke, H., Zhou, A., Power, C., McCarthy, M. I., Michos, E. D., Boerwinkle, E., Weinstein, S. J., Freedman, N. D., Huang, W. Y., Van Schoor, N. M., Van Der Velde, N., Groot, L. C. P. G. M. D., Enneman, A., Cupples, L. A., Booth, S. L., Vasan, R. S., Liu, C. T., Zhou, Y., Ripatti, S., Ohlsson, C., Vandenput, L., Lorentzon, M., Eriksson, J. G., Shea, M. K., Houston, D. K., Kritchevsky, S. B., Liu, Y., Lohman, K. K., Ferrucci, L., Peacock, M., Gieger, C., Beekman, M., Slagboom, E., Deelen, J., Heemst, DI. V., Kleber, M. E., März, W., De Boer, I. H., Wood, A. C., Rotter, J. I., Rich, S. S., Robinson-Cohen, C., Den Heijer, M., Jarvelin, M. R., Cavadino, A., Joshi, P. K., Wilson, J. F., Hayward, C., Lind, L., Michaëlsson, K., Trompet, S., Zillikens, M. C., Uitterlinden, A. G., Rivadeneira, F., Broer, L., Zgaga, L., Campbell, H., Theodoratou, E., Farrington, S. M., Timofeeva, M., Dunlop, M. G., Valdes, A. M., Tikkanen, E., Lehtimäki, T., Lyytikäinen, L. P., Kähönen, M., Raitakari, O. T., Mikkilä, V., Ikram, M. A., Sattar, N., Jukema, J. W., Wareham, N. J., Langenberg, C., Forouhi, N. G., Gundersen, T. E., Khaw, K. T., Butterworth, A. S., Danesh, J., Spector, T., Wang, T. J., Hyppönen, E., Kraft, P. & Kiel, D. P., 1 Dec 2018, In : Nature Communications. 9, 1, 260.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Vojinovic, D., Adams, H. H., Jian, X., Yang, Q., Smith, A. V., Bis, J. C., Teumer, A., Scholz, M., Armstrong, N. J., Hofer, E., Saba, Y., Luciano, M., Bernard, M., Trompet, S., Yang, J., Gillespie, N. A., van der Lee, S. J., Neumann, A., Ahmad, S., Andreassen, O. A. & 71 others, Ames, D., Amin, N., Arfanakis, K., Bastin, M. E., Becker, D. M., Beiser, A. S., Beyer, F., Brodaty, H., Bryan, R. N., Bülow, R., Dale, A. M., De Jager, P. L., Deary, I. J., DeCarli, C., Fleischman, D. A., Gottesman, R. F., van der Grond, J., Gudnason, V., Harris, T. B., Homuth, G., Knopman, D. S., Kwok, J. B., Lewis, C. E., Li, S., Loeffler, M., Lopez, O. L., Maillard, P., El Marroun, H., Mather, K. A., Mosley, T. H., Muetzel, R. L., Nauck, M., Nyquist, P. A., Panizzon, M. S., Pausova, Z., Psaty, B. M., Rice, K., Rotter, J. I., Royle, N., Satizabal, C. L., Schmidt, R., Schofield, P. R., Schreiner, P. J., Sidney, S., Stott, D. J., Thalamuthu, A., Uitterlinden, A. G., Valdés Hernández, M. C., Vernooij, M. W., Wen, W., White, T., Witte, A. V., Wittfeld, K., Wright, M. J., Yanek, L. R., Tiemeier, H., Kremen, W. S., Bennett, D. A., Jukema, J. W., Paus, T., Wardlaw, J. M., Schmidt, H., Sachdev, P. S., Villringer, A., Grabe, H. J., Longstreth, W. T., van Duijn, C. M., Launer, L. J., Seshadri, S., Ikram, M. A. & Fornage, M., 26 Sep 2018, In : Nature Communications. 9, 1, p. 3945

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Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Early Growth Genetics (EGG) Consortium, 2018, In : Human Molecular Genetics. 27, 4, p. 742-756

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Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD

Van der Auwera, S., Peyrot, W. J., Milaneschi, Y., Hertel, J., Baune, B., Breen, G., Byrne, E., Dunn, E. C., Fisher, H., Homuth, G., Levinson, D., Lewis, C., Mills, N., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rietschel, M., Ripke, S., Sullivan, P. & 7 others, Teumer, A., Völzke, H., Boomsma, D. I., Wray, N. R., Penninx, B., Grabe, H. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2018, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 177, 1, p. 40-49 10 p.

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Genome-wide identification of directed gene networks using large-scale population genomics data

BIOS (Biobank-based Integrative Omics Study) Consortium, 2018, In : Nature Communications. 9, 1, 3097.

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Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland, 2018, In : PLoS ONE. 13, 12, e0209160.

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Genome-wide meta-analysis of cognitive empathy: Heritability, and correlates with sex, neuropsychiatric conditions and cognition

Warrier, V., Grasby, K. L., Uzefovsky, F., Toro, R., Smith, P., Chakrabarti, B., Khadake, J., Mawbey-Adamson, E., Litterman, N., Hottenga, J. J., Lubke, G., Boomsma, D. I., Martin, N. G., Hatemi, P. K., Medland, S. E., Hinds, D. A., Bourgeron, T. & Baron-Cohen, S., 2018, In : Molecular Psychiatry. 23, 6, p. 1402-1409

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Genomic and expression analyses identify a disease-modifying variant for Fibrostenotic Crohn's disease

Visschedijk, M. C., Spekhorst, L. M., Cheng, S-C., van Loo, E. S., Dianne Jansen, B. H., Blokzijl, T., Kil, H., de Jong, D. J., Pierik, M., Maljaars, J. P. W. J., van der Woude, C. J., van Bodegraven, A. A., Oldenburg, B., Löwenberg, M., Nieuwenhuijs, V. B., Imhann, F., van Sommeren, S., Alberts, R., Xavier, R. J., Dijkstra, G. & 4 others, Faber, K. N., Marcelo Aldaz, C., Weersma, R. K. & Festen, E. A. M., 2018, In : Journal of Crohn's and Colitis. 12, 5, p. 582-588

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Genomic dissection of Bipolar Disorder and Schizophrenia, including 28 subphenotypes

Ruderfer, D. M., Ripke, S., McQuillin, A., Boocock, J., Stahl, E. A., Pavlides, J. M. W., Mullins, N., Charney, A. W., Ori, A. P. S., Loohuis, L. M. O., Domenici, E., Di Florio, A., Papiol, S., Kalman, J. L., Trubetskoy, V., Adolfsson, R., Agartz, I., Agerbo, E., Akil, H., Albani, D. & 33 others, Albus, M., Alda, M., Alexander, M., Alliey-Rodriguez, N., Als, T. D., Amin, F., Anjorin, A., Arranz, M. J., Awasthi, S., Bacanu, S. A., Badner, J. A., Baekvad-Hansen, M., Bakker, S., Band, G., Barchas, J. D., Barroso, I., Bass, N., Bauer, M., Baune, B. T., Begemann, M., Bellenguez, C., Belliveau, R. A., Bellivier, F., Bender, S., Bene, J., Bergen, S. E., Berrettini, W. H., Kupka, R., Meijer, C. J., Posthuma, D., Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, Psychosis Endophenotypes International Consortium & Wellcome Trust Case-Control Consortium, 14 Jun 2018, In : Cell. 173, 7, p. 1705-1715.e16

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Genomic heterogeneity as a barrier to precision medicine in gastroesophageal adenocarcinoma

Pectasides, E., Stachler, M. D., Derks, S., Liu, Y., Maron, S., Islam, M., Alpert, L., Kwak, H., Kindler, H., Polite, B., Sharma, M. R., Allen, K., O’Day, E., Lomnicki, S., Maranto, M., Kanteti, R., Fitzpatrick, C., Weber, C., Setia, N., Xiao, S-Y. & 37 others, Hart, J., Nagy, R. J., Kim, K-M., Choi, M-G., Min, B-H., Nason, K. S., O’Keefe, L., Watanabe, M., Baba, H., Lanman, R., Agoston, A. T., Oh, D. J., Dunford, A., Thorner, A. R., Ducar, M. D., Wollison, B. M., Coleman, H. A., Ji, Y., Posner, M. C., Roggin, K., Turaga, K., Chang, P., Hogarth, K., Siddiqui, U. D., Gelrud, A., Ha, G., Freeman, S. S., Rhoades, J., Reed, S., Gydush, G., Rotem, D., Davison, J., Imamura, Y., Adalsteinsson, V., Lee, J., Bass, A. J. & Catenacci, D. V., 2018, In : Cancer discovery. 8, 1, p. 37-48

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Genomics features (GF) and integration with MRI radiomics features (RF) to develop a prognostic model in oral cavity squamous cell carcinoma (OSCC)

Cavalieri, S., De Cecco, L., Calareso, G., Silva, M., Gazzani, S. E., Bologna, M., Nauta, I., Wesseling, F., Lopez Perez, L., Shefi, R., Tountopoulos, V., Fico, G., Scheckenbach, K., Brakenhoff, R. H., Hoebers, F., Canevari, S., Poli, T., Licitra, L., Mainardi, L. & BD2Decide Consortium, 1 Oct 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii376

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Gestational diabetes alters microRNA signatures in human feto-placental endothelial cells depending on fetal sex

Strutz, J., Cvitic, S., Hackl, H., Kashofer, K., Appel, H. M., Thüringer, A., Desoye, G., Koolwijk, P. & Hiden, U., 2018, In : Clinical science (London, England : 1979). 132, 22, p. 2437-2449

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Gestational surrogacy: results of 10 years of experience in the Netherlands

Peters, H. E., Schats, R., Verhoeven, M. O., Mijatovic, V., de Groot, C. J. M., Sandberg, J. L., Peeters, I. P. & Lambalk, C. B., 1 Dec 2018, In : Reproductive BioMedicine Online. 37, 6, p. 725-731 7 p.

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Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania

Santos, S., Eekhout, I., Voerman, E., Gaillard, R., Barros, H., Charles, M-A., Chatzi, L., Chevrier, C. C., Chrousos, G. P., Corpeleijn, E., Costet, N., Crozier, S., Doyon, M., Eggesbø, M., Fantini, M. P., Farchi, S., Forastiere, F., Gagliardi, L., Georgiu, V., Godfrey, K. M. & 60 others, Gori, D., Grote, V., Hanke, W., Hertz-Picciotto, I., Heude, B., Hivert, M-F., Hryhorczuk, D., Huang, R-C., Inskip, H., Jusko, T. A., Karvonen, A. M., Koletzko, B., Küpers, L. K., Lagström, H., Lawlor, D. A., Lehmann, I., Lopez-Espinosa, M-J., Magnus, P., Majewska, R., Mäkelä, J., Manios, Y., McDonald, S. W., Mommers, M., Morgen, C. S., Moschonis, G., Murínová, Ľ., Newnham, J., Nohr, E. A., Andersen, A-M. N., Oken, E., Oostvogels, A. J. J. M., Pac, A., Papadopoulou, E., Pekkanen, J., Pizzi, C., Polanska, K., Porta, D., Richiardi, L., Rifas-Shiman, S. L., Roeleveld, N., Santa-Marina, L., Santos, A. C., Smit, H. A., Sørensen, T. I. A., Standl, M., Stanislawski, M., Stoltenberg, C., Thiering, E., Thijs, C., Torrent, M., Tough, S. C., Trnovec, T., van Gelder, M. M. H. J., van Rossem, L., von Berg, A., Vrijheid, M., Vrijkotte, T. G. M., Zvinchuk, O., van Buuren, S. & Jaddoe, V. W. V., 2018, In : BMC Medicine. 16, 1, 201.

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