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1988

A prospective study on the dose dependency of cardiotoxicity induced by mitomycin C

Verwey, J., Funke-Kupper, A. J., Teule, G. J. J. & Pinedo, H. M., 1988, In : Medical oncology and tumor pharmacotherapy. 5, 3, p. 159-163

Research output: Contribution to journalArticleAcademicpeer-review

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Are prepared fears less severe, but more resistant to treatment?

Merckelbach, H., van den Hout, M. A., Hoekstra, R. & Van Oppen, P., 1 Jan 1988, In : Behaviour Research and Therapy. 26, 6, p. 527-530 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Chylothorax and chylopericardium

Smeets, R. E. H., Van Jaarsveld, B. C., Gooszen, H. C. & Schipper, R. M., 1 Jan 1988, In : Nederlands Tijdschrift voor Geneeskunde. 132, 34, p. 1584-1587 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

CNS pathogenesis following a dual viral infection with Semliki Forest (alphavirus) and Langat (flavivirus)

Amor, S. & Webb, H. E., Apr 1988, In : International Journal of Experimental Pathology. 69, 2, p. 197-208 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Combined radiation therapy and daily low-dose cisplatin for inoperable, locally advanced non-small cell lung cancer: results of a phase II trial

Boven, E., Tierie, A. H., Stam, J. & Pinedo, H. M., 1988, In : Seminars in Oncology. 15, 6, suppl 7 (dec,), p. 18-29

Research output: Contribution to journalArticleAcademicpeer-review

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Comparison of Bombesin‐, ACTH‐, and β‐Endorphin‐induced Grooming: Antagonism by Haloperidol, Naloxone, and Neurotensin

GREIDANUS, T. B. VAN. WIMERSMA., VAN DE BRUG, F., DE BRUIJCKERE, L. M., PABST, P. H. M. A., RUESINK, R. W., HULSHOF, R. L. E., VAN BERCKEL, B. N. M., ARISSEN, S. M., KONING, E. J. P. DE. & DONKER, D. K., 1 Jan 1988, In : Annals of the New York Academy of Sciences. 525, 1, p. 219-227 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cordocentesis in the assessment of the small-for-gestational age fetus

Bilardo, C. M. & Nicolaides, K. H., 1988, In : Fetal Therapy. 3, 1-2, p. 24-30

Research output: Contribution to journalArticleAcademicpeer-review

Development of an antibody-capture IgM-enzyme-linked immunosorbent assay for diagnosis of acute Epstein-Barr virus infections

Wielaard, F., Scherders, J., Dagelinckx, C., Middeldorp, J. M., Sabbe, L. J. & Van Belzen, C., Sep 1988, In : Journal of Virological Methods. 21, 1-4, p. 105-15 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

DILATATION KYSTIQUE DU CHOLEDOQUE. NEUF OBSERVATIONS

Girbes, A. R. J., Slooff, M. J. H., Hesselink, E. J., Zwierstra, R. P. & Van Schilfgaarde, R., 1 Jan 1988, In : PRESSE MEDICALE. 17, 39, p. 2073-2076 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Doxorubicin treatment increases metastasis of prostate tumor (R3327-MatLyLu)

Geldof, A. A. & Rao, B. R., 1 Dec 1988, In : Anticancer Research. 8, 6, p. 1335-1339 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

12 Downloads (Pure)

DUP 785 (NSC 368390): schedule-dependency of growth inhibitory and antipyrimidine effects

Schwartsmann, G., Peters, G. J., Laurensse, E., de Waal, F. C., Loonen, A. H., Leyva, A. & Pinedo, H. M., 1988, In : Biochemical Pharmacology. 37, 17, p. 3257-3266

Research output: Contribution to journalArticleAcademicpeer-review

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2 Downloads (Pure)

Effect of onendogenous glutathione, superoxide dismutases, catalase, and glutathione peroxidase on adriamycin tolerance of Chinese hamster ovary cells

Keizer, H. G., van Rijn, J., Pinedo, H. M. & Joenje, H., 1988, In : Cancer Research. 48, p. 4493-4497

Research output: Contribution to journalArticleAcademicpeer-review

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Effects of local hyperthermia on the motor function of the rat sciatic nerve

Wondergem, J., Haveman, J., Rusman, V., Sminia, P. & Van Dijk, J. D., Mar 1988, In : International journal of radiation biology and related studies in physics, chemistry, and medicine. 53, 3, p. 429-38 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

EFFECTS OF OPIATE RECEPTOR BLOCKADE ON GONADOTROPHIN SECRETION BEFORE AND AFTER ADMINISTRATION OF THE OESTROGEN RECEPTOR BLOCKER TAMOXIFEN IN EUGONADAL MEN

SPIJKSTRA, J. J., SPINDER, T., GOOREN, L. J. G. & VAN KESSEL, H., 1 Jan 1988, In : Clinical Endocrinology. 29, 2, p. 179-188 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Effects of the ortho quinone and catechol of the anti tumor drug VP l6 2l3 on the biological activity of single stranded and double stranded 0Xl74 DNA

van Maanen, J. M. S., Lafleur, M. V. M., van den Akker, E., de Ruiter, C., Kootstra, P. R., Pappie, D., de Vries, J., Retel, J. & Pinedo, H. M., 1988, In : Biochemical Pharmacology. 37, 19, p. 3579-3589

Research output: Contribution to journalArticleAcademicpeer-review

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Efficacy and advantages in the use of low doses of anandron and estrogen combination in the treatment of prostate cancer

Rao, B. R., Geldof, A. A., van Der Wilt, C. L. & de Voogt, H. J., 1 Jan 1988, In : The Prostate. 13, 1, p. 69-78 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Endocrine tumors

van der Hoeven, J. J. M. & Pinedo, H. M., 1988, Cancer Chemotherapy & Biological Response Modifiers Annual. Elsevier Science Publishers, p. 265-270

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Open Access
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Epitope-mapping on the Epstein-Barr virus major capsid protein using systematic synthesis of overlapping oligopeptides

Middeldorp, J. M. & Meloen, R. H., Sep 1988, In : Journal of Virological Methods. 21, 1-4, p. 147-59 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Epstein-Barr virus specific marker molecules for early diagnosis of infectious mononucleosis

Middeldorp, J. M. & Herbrink, P., Sep 1988, In : Journal of Virological Methods. 21, 1-4, p. 133-46 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Erotosexuality in a man lacking physiological postnatal androgen exposure

Gooren, L. J. G. & Cohen-Kettenis, P., 1 Jan 1988, In : Journal of Psychology and Human Sexuality. 1, 1, p. 129-135 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Evidence for a role of heat-shock proteins in proliferation after heat treatment of synchronized mouse neuroblastoma cells

Van Dongen, G. & Van Wijk, R., 1 Jan 1988, In : Radiation Research. 113, 2, p. 252-267 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Failure to condition evaluative and electrodermal responses to neutral stimuli by means of prepared cues.

Merckelbach, H., van den Hout, M. A. & van Oppen, P., 1 Jan 1988, In : Activitas nervosa superior. 30, 3, p. 161-168 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Frequency of births with potentially avoidable serious chromosomal anomalies in EEC countries, 1979-1982

Ten Kate, L. P., Dolk, H., Cornel, M. C., De Wals, P., Te Meerman, G. J., Lechat, M. F. & Weatherall, J. A. C., 1 Jan 1988, In : Journal of Epidemiology and Community Health. 42, 3, p. 266-270 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Further analysis of the neuropharmacological profile of 9-amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease

Drukarch, B., Leysen, J. E. & Stoof, J. C., 1988, In : Life Sciences. 42, 9, p. 1011-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

9 Downloads (Pure)

In-beamlight absorption measurement of anthracyclines in cells with a flow through system

Lankelma, J., Koopman, G., van Grondelle, R. & Pinedo, H. M., 1988, In : Biochimica et Biophysica Acta (BBA) - General Subjects. 964, p. 200-206

Research output: Contribution to journalArticleAcademicpeer-review

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Increase of daunorubicin and vincristine accumulation in multidrug resistant human ovarian carcinoma cells by a monoclonal antibody reacting with P-plycoprotein

Broxterman, H. J., Kuiper, C. M., Schuurhuis, G. J., Tsuruo, T., Pinedo, H. M. & Lankelma, J., 1988, In : Biochemical Pharmacology. 37, 12, p. 2389-2393

Research output: Contribution to journalArticleAcademicpeer-review

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Induction of a rapid increase in ATP consumption by verapamil in multidrug resistant tumor cells

Broxterman, H. J., Pinedo, H. M., Kuiper, C. M., Kaptein, L. C. M., Schuurhuis, G. J. & Lankelma, J., 1988, In : FASEB Journal. 2, p. 2278-2282

Research output: Contribution to journalArticleAcademicpeer-review

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Interdigitating cells and dendritic cells of the mouse identified by monoclonal antibodies: interaction with lymphocyte subsets

Breel, M., Mebius, R. & Kraal, G., 1988, In : Advances in Experimental Medicine and Biology. 237, p. 757-63 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

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In vivo potentiation of 5 fluorouracil by leucovorin in murine colon carcinoma

Nadal, J. C., Pinedo, H. M., van Groeningen, C. J. & Peters, G. J., 1988, In : Biomedicine and Pharmacotherapy. 42, p. 387-393

Research output: Contribution to journalArticleAcademicpeer-review

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Iproplatin and carboplatin induced toxicities: overview of phase II clinical trials conducted by the EORTC Early Clinical Trials Group (ECTG)

van Glabbeke, M., Renard, J., Pinedo, H. M., Cavalli, F., Vermorken, J. B., Sessa, C., Abele, R., Clavel, M. & Monfardini, S., 1988, In : European Journal of Cancer and Clinical Oncology.

Research output: Contribution to journalArticleAcademicpeer-review

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Iproplatin and carboplatin induced toxicities. Overview of Phase II clinical trials conducted by the EORTC Early Clinical Trials Cooperative Group and the EORTC Data Center

van Glabbeke, M., Renard, J., Pinedo, H. M., Vermorken, J. B., Sessa, C., Abele, R., Clavel, M. & Montfardini, S., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 2, p. 255-262

Research output: Contribution to journalArticleAcademicpeer-review

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Mean blood velocities and flow impedance in the fetal descending thoracic aorta and common carotid artery in normal pregnancy

Bilardo, C. M., Campbell, S. & Nicolaides, K. H., 1988, In : Early Human Development. 18, 2-3, p. 213-221

Research output: Contribution to journalArticleAcademicpeer-review

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Mechanism of action of the antitumor drug VP l6 2l3: A review

van Maanen, J. M. S., Retel, J., de Vries, J. & Pinedo, H. M., 1988, In : Journal of the National Cancer Institute. 80, 19, p. 1526-1533

Research output: Contribution to journalArticleAcademicpeer-review

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Merits and considerations in the use of anti-androgen

Rao, B. R., de Voogt, H. J., Geldof, A. A., Gooren, L. J. G. & Bouman, F. G., 1 Jan 1988, In : Journal of Steroid Biochemistry. 31, 4, p. 731-737 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Mitomycin C injucted organ toxicity in wistar rats. A study with special focus in the kidney

Verwey, J., Kerpel Fronius, S., Stuurman, M., van Friet, A. J., van Hattum, A. H., de Vries, J. & Pinedo, H. M., 1988, In : Journal of Cancer Research and Clinical Oncology. 114, p. 137-141

Research output: Contribution to journalArticleAcademicpeer-review

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Morphometric study of myocardial changes during doxorubicin induced cardiomyopathy in mice

van der Vijgh, W. J. F., van Velzen, D., van der Poort, S. E. J. M., Schlüper, H. M. M., Mross, K., Feyen, J. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 10, p. 1603-1608

Research output: Contribution to journalArticleAcademicpeer-review

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Negative phase II trial of menogaril in advanced squamous, adeno and large cell carcinoma of the lung

Joss, R. A., Monfardini, S., Hansen, H., Dombernowsky, P., Renard, J. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 2, p. 263-265

Research output: Contribution to journalArticleAcademicpeer-review

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Peters, G.J. A sensitive nonradioactive assay for pyrimidine nucleoside phosphorylase using reverse phase high performance liquid chromatography

Laurensse, E., Pinedo, H. M. & Peters, G. J., 1988, In : Clinica Chimica Acta. 178, p. 71-78

Research output: Contribution to journalArticleAcademicpeer-review

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Pharmacokinetics and metabolism of epirubicin and doxorubicin in humans

Mross, K., Maessen, P., van der Vijgh, W. J. F., Gall, H., Boven, E. & Pinedo, H. M., 1988, In : Journal of Clinical Oncology. 6, p. 517-526

Research output: Contribution to journalArticleAcademicpeer-review

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Pharmacokinetics of 5 fluorouracil assesses with a sensitive mass spectrometric method in patients on a dose escalation schedule

van Groeningen, C. J., Pinedo, H. M., Heddes, J., Kok, R. M., de Jong, A. P. J. M., Wattel, E., Peters, G. J. & Lankelma, J., 1988, In : Cancer Research. 48, p. 6956-6961

Research output: Contribution to journalArticleAcademicpeer-review

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Pharmacokinetics of brequinar sodium (NSC 368390; DUP 785) in cerebrospinal Fluid

Schwartsmann, G., van der Vijgh, W. J. F., Klein, I., van Groeningen, C. J., Vermorken, J. B. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 12, p. 1903-1904

Research output: Contribution to journalArticleAcademicpeer-review

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Pharmacokinetics of free and total platinum species after rapid and prolonged infusions of aqua(l,l-bis(aminomethylcyclohexane) sulfatoplatinum(11) (spiroplatin) during phase I trial

van der Vijgh, W. J. F., Elferink, F., Vermorken, J. B., ten Bokkel Huinink, W. W., Klein, I., Gall, H., Simonetti, G., McVie, J. G. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, p. 621-627

Research output: Contribution to journalArticleAcademicpeer-review

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Phase II study of Iroplatin (CHIP, JM 9) in advanced testicular cancers progressing after prior chemotherapy

Clavel, M., Montfardini, S., Gundersen, S., Kaye, S., Siegenthaler, P., Renard, J., van Glabbeke, M. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 8, p. 1345-1348

Research output: Contribution to journalArticleAcademicpeer-review

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10 Downloads (Pure)

Phase II study of TCNU in advanced breast cancer

Dombernowsky, P., Clavel, M., Smyth, J. F., Howell, A., van Glabekke, M., Renard, J. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 8, p. 1377-1378

Research output: Contribution to journalArticleAcademicpeer-review

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Pinedo, H.M. Pharmacokinetics and toxicity of mitomycin C in rodents, given alone, in combination, or after induction of microsomal drug metabolism

Kerper-Fronius, S., Verweij, J., Stuurman, M., Kanyar, B., Lelieveld, P. & Pinedo, H. M., 1988, In : Cancer Chemotherapy and Pharmacology. 22, p. 104-108

Research output: Contribution to journalArticleAcademicpeer-review

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Pinedo H.M. Monoclonal antibody JSB-l detects a highly conserved epitope on the P-glycoprotein associated with multidrug resistance.

Scheper, R. J., Bulte, W. J. M., Brakkee, J. G. P., Quak, J. J., Schoot, E. V. D., Palm, A. J. M., Meijer, C. J. L. M., Broxterman, H. J., Kuiper, C. M., Lankelma, J. & Pinedo, H. M., 1988, In : International Journal of Cancer. 42, p. 389-394

Research output: Contribution to journalArticleAcademicpeer-review

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Preclinical antitumor activity of 5-aza-2′-deoxycytidine agains human head and neck cancer xenografts

Braakhuis, B. J. M., van Dongen, G. A. M. S., van Walsum, M., Leyva, A. & Snow, G. B., 1 Dec 1988, In : Investigational New Drugs. 6, 4, p. 299-304 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Downloads (Pure)

Preclinical phase II studies in human tumor lines: a European multi-center study

Boven, E., Winograd, B., Fodstad, O., Lobbezoo, M. W. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 3, p. 567-573

Research output: Contribution to journalArticleAcademicpeer-review

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Rapid diagnosis of genital herpes simplex infection by an indirect ELISA method

Skar, A. G., Middeldorp, J., Gundersen, T., Rollag, H. & Degrè, M., Dec 1988, In : NIPH annals. 11, 2, p. 59-65 7 p.

Research output: Contribution to journalArticleAcademicpeer-review