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1988
14 Downloads (Pure)

Negative phase II trial of menogaril in advanced squamous, adeno and large cell carcinoma of the lung

Joss, R. A., Monfardini, S., Hansen, H., Dombernowsky, P., Renard, J. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 2, p. 263-265

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Peters, G.J. A sensitive nonradioactive assay for pyrimidine nucleoside phosphorylase using reverse phase high performance liquid chromatography

Laurensse, E., Pinedo, H. M. & Peters, G. J., 1988, In : Clinica Chimica Acta. 178, p. 71-78

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Pharmacokinetics and metabolism of epirubicin and doxorubicin in humans

Mross, K., Maessen, P., van der Vijgh, W. J. F., Gall, H., Boven, E. & Pinedo, H. M., 1988, In : Journal of Clinical Oncology. 6, p. 517-526

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Pharmacokinetics of 5 fluorouracil assesses with a sensitive mass spectrometric method in patients on a dose escalation schedule

van Groeningen, C. J., Pinedo, H. M., Heddes, J., Kok, R. M., de Jong, A. P. J. M., Wattel, E., Peters, G. J. & Lankelma, J., 1988, In : Cancer Research. 48, p. 6956-6961

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Pharmacokinetics of brequinar sodium (NSC 368390; DUP 785) in cerebrospinal Fluid

Schwartsmann, G., van der Vijgh, W. J. F., Klein, I., van Groeningen, C. J., Vermorken, J. B. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 12, p. 1903-1904

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Pharmacokinetics of free and total platinum species after rapid and prolonged infusions of aqua(l,l-bis(aminomethylcyclohexane) sulfatoplatinum(11) (spiroplatin) during phase I trial

van der Vijgh, W. J. F., Elferink, F., Vermorken, J. B., ten Bokkel Huinink, W. W., Klein, I., Gall, H., Simonetti, G., McVie, J. G. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, p. 621-627

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Phase II study of Iroplatin (CHIP, JM 9) in advanced testicular cancers progressing after prior chemotherapy

Clavel, M., Montfardini, S., Gundersen, S., Kaye, S., Siegenthaler, P., Renard, J., van Glabbeke, M. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 8, p. 1345-1348

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Phase II study of TCNU in advanced breast cancer

Dombernowsky, P., Clavel, M., Smyth, J. F., Howell, A., van Glabekke, M., Renard, J. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 8, p. 1377-1378

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Pinedo, H.M. Pharmacokinetics and toxicity of mitomycin C in rodents, given alone, in combination, or after induction of microsomal drug metabolism

Kerper-Fronius, S., Verweij, J., Stuurman, M., Kanyar, B., Lelieveld, P. & Pinedo, H. M., 1988, In : Cancer Chemotherapy and Pharmacology. 22, p. 104-108

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Pinedo H.M. Monoclonal antibody JSB-l detects a highly conserved epitope on the P-glycoprotein associated with multidrug resistance.

Scheper, R. J., Bulte, W. J. M., Brakkee, J. G. P., Quak, J. J., Schoot, E. V. D., Palm, A. J. M., Meijer, C. J. L. M., Broxterman, H. J., Kuiper, C. M., Lankelma, J. & Pinedo, H. M., 1988, In : International Journal of Cancer. 42, p. 389-394

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Preclinical antitumor activity of 5-aza-2′-deoxycytidine agains human head and neck cancer xenografts

Braakhuis, B. J. M., van Dongen, G. A. M. S., van Walsum, M., Leyva, A. & Snow, G. B., 1 Dec 1988, In : Investigational New Drugs. 6, 4, p. 299-304 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Preclinical phase II studies in human tumor lines: a European multi-center study

Boven, E., Winograd, B., Fodstad, O., Lobbezoo, M. W. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 3, p. 567-573

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Rapid diagnosis of genital herpes simplex infection by an indirect ELISA method

Skar, A. G., Middeldorp, J., Gundersen, T., Rollag, H. & Degrè, M., Dec 1988, In : NIPH annals. 11, 2, p. 59-65 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Relation between infarct size and left ventricular performance assessed in patients with first acute myocardial infarction randomized to intracoronary thrombolytic therapy or to conventional treatment

Van Der Laarse, A., Kerkhof, P. L. M., Vermeer, F., Serruys, P. W., Hermens, W. T., Verheugt, F. W. A., Bär, F. W., Krauss, X. H., Van Der Wall, E. E. & Simoons, M. L., 1 Jan 1988, In : The American Journal of Cardiology. 61, 1, p. 1-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Semi Quinone formation from the catechol and ortho-quinone metabolites of the antitumor agent VP l6 213

van Maanen, J. M. S., Verkerk, U. H., Broersen, J., Lafleur, M. V. M., de Vries, J., Retel, J. & Pinedo, H. M., 1988, In : Free radical research. 4, 6, p. 371-384

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Sex reassignment surgery: A study of 141 dutch transsexuals

Kuiper, B. & Cohen-Kettenis, P., 1 Oct 1988, In : Archives of Sexual Behavior. 17, 5, p. 439-457 19 p.

Research output: Contribution to journalArticleAcademicpeer-review

Short-term patterns of pulsatile luteinizing hormone secretion do not differ between male-to-female transsexuals and heterosexual men

Spijkstra, J. J., Spinder, T. & Gooren, L. J. G., 1 Jan 1988, In : Psychoneuroendocrinology. 13, 3, p. 279-283 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Structure Bioactivation relationship of a series of podophyllotoxin derivatives

van Maanen, J. M. S., van den Akker, E., de Vries, J., Pakkenist, T. R. J., Lankelma, J., Retel, J. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, 9, p. 1415-1419

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Swelling of metastatic tumours with high dose interleukin-2 therapy

Goey, S. H., Voerman, H. J., Strack van Schijndel, R. J. M., van der Hoeven, J. J. M., Wagstaff, J., Thijs, L. G. & Pinedo, H. M., 1988, In : New England Journal of Medicine. 318, p. 643-644

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Tetrahydro-aminoacridine: een veelbelovende 'therapie' voor de ziekte van Alzheimer?

Drukarch, B. & Stoof, J. C., 1 Oct 1988, In : Nederlands Tijdschrift voor Geneeskunde. 132, 40, p. 1833-5 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

The anti-ischaemic activity of the novel compound, CERM 11956, compared with that of bepridil and nifedipine in isolated guinea-pig hearts

Boddeke, E. W. G. M., Wilffert, B., Heynis, J. B., Hugtenburg, J. G., Jap, W. T. J., Veldsema-Currie, R. D. & Van Zwieten, P. A., 10 May 1988, In : European Journal of Pharmacology. 149, 3, p. 195-203 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The interaction of interdigitating cells and lymphocytes in vitro and in vivo

Breel, M., Mebius, R. & Kraal, G., Feb 1988, In : Immunology. 63, 2, p. 331-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

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The main steps in the development of anticancer agents

Schwartsmann, G., Winograd, B. & Pinedo, H. M., 1988, In : Radiotherapy and Oncology. 12, p. 301-313

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The pharmacokinetic plasma profile of mitomycin C, measured after sequential intermittent intravenous administration

Lankelma, J., Stuurman, M., van Hoogenhuijze, J., van Bochove, A., Vermorken, J. B., Verwey, J. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, p. 175-180

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The quantification of gammacarboxyglutamic acid residues in plasma-osteocalcin

Soute, B. A. M., Ulrich, M. M. W., Knapen, M. H. J., van Haarlem, L. J. M. & Vermeer, C., 1 Sep 1988, In : Calcified Tissue International. 43, 3, p. 184-188 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

The role of oxygen-derived five radicals in the cytotoxicity of doxorubicin in multidrug resistant and sensitive human ovarian cancer cells

Cervantes, A., Pinedo, H. M., Lankelma, J. & Schuurhuis, G. J., 1988, In : Cancer Letters. 41, p. 169-177

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Vitamin K-dependent carboxylation. A synthetic peptide based upon the γ-carboxylation recognition site sequence of the prothrombin propeptide is an active substrate for the carboxylase in vitro

Ulrich, M. M. W., Furie, B. C., Jacobs, M. R., Vermeer, C. & Furie, B. C., 1 Jan 1988, In : Journal of Biological Chemistry. 263, 20, p. 9697-9702 6 p.

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Vitamin K is no antagonist for the action of warfarin in rat osteosarcoma UMR 106

Ulrich, M. M. W., Knapen, M. H. J., Herrmann Erlee, M. P. M. & Vermeer, C., 1 Apr 1988, In : Thrombosis Research. 50, 1, p. 27-32 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

1987

9-Amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease, inhibits acetylcholinesterase activity and slow outward K+ current

Drukarch, B., Kits, K. S., Van der Meer, E. G., Lodder, J. C. & Stoof, J. C., 2 Sep 1987, In : European Journal of Pharmacology. 141, 1, p. 153-7 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Absorption of epi doxorubicin after administration in patients with in situ transitional cell carcinoma of the bladder

Mross, K., Maessen, P., van der Vijgh, W. J. F., Bogdanowicz, J. F., Kurth, K. H. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology. 23, 3, p. 505-508

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Adriamycin versus Epirubicin in ancced soft tissue sarcomas. A randomized phase II/phase III study of the EORTC Soft Tissue and Bone Sarcoma Group

Mouridsen, H. T., Bastholt, L., Somers, R., Santoro, A., Bramwell, V., Mulder, J. H., van Oosterom, A. T., Buesa, J., Pinedo, H. M., Thomas, D. & Sylvester, R., 1987, In : European Journal of Cancer and Clinical Oncology.

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Analysis of human ascites effect on clonogenic growth of human tumor cell lines and NRK 49F cells in soft agar

Broxterman, H. J., Sprenkels-Schotte, C., Engelen, P., Leyva, A. & Pinedo, H. M., 1987, In : Int. J. Cell Cloning. 5, p. 158-169

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Androgen action blockade does not result in reduction in size but changes histology of the normal human prostate

De Voogt, H. J., Rao, B. R., Geldof, A. A., Gooren, L. J. G. & Bouman, F. G., 1 Jan 1987, In : The Prostate. 11, 4, p. 305-311 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

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A phase II study of carboplatin in advance d or metastatic stomach cancer

Beer, M., Cavalli, F., Kaye, S. B., Lev, L. L., Clavel, M., Smyth, J., van Glabbeke, M., Renard, J. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology.

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A sensitive, non radiometric assay for dihyroorotic acid de hydrogenase using anion exchange high performance liquid chromatogra phy

Peters, G. J., Laurensse, E., Leyva, A. & Pinedo, H. M., 1987, In : Analytical Biochemistry. 161, p. 32-38

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A sensitive enzyme-linked immunosorbent assay for the detection of herpes simplex virus antigens

Middeldorp, J. M., Hooymans, A. M., Kocken, A. J., van Loon, A. M., Emsbroek, J. A. & Coutinho, R. A., Aug 1987, In : Journal of Virological Methods. 17, 1-2, p. 159-74 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Authors' Reply

Hackett, G. A., Campbell, S., Nicolaides, K. H. & Bilardo, C., 1 Jan 1987, In : British medical journal (Clinical research ed.). 294, 6572, 1 p.

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Chemical reactivity of cisplatin bound to human plasma proteins

Hegedus, L., van der Vijgh, W. J. F., Klein, I., Kerper Fronius, S. & Pinedo, H. M., 1987, In : Cancer Chemotherapy and Pharmacology. 20, p. 211-212

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Chemotherapy of advanced soft tissue sarcomas in adults

Pinedo, H. M. & Kenis, Y., 1987, In : Cancer Treatment Reviews. 4, 2, p. 67-86

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Clinical trials in advanced breast cancer

Schwartsmann, G. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology. 23, 6, p. 595-597

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Comparative pharmacokinetics of cisplatin and three analogs in mice and man

van Hennik, M. B., van der Vijgh, W. J. F., Klein, I., Elferink, F., Vermorken, J. B., Winograd, B. & Pinedo, H. M., 1987, In : Cancer Research. 47, p. 6297-6301

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Cytochrome P 450 mediated O-demethylation: a route in the metabolic activation of etoposide (VP 16 213)

van Maanen, J. M. S., de Vries, J., Pappie, D., van den Akker, E., Lafleur, M. V. M., Retel, J., van der Greef, J. & Pinedo, H. M., 1987, In : Cancer Research. 47, p. 4658-4662

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Daunomycin accumulation in resistant tumor cells as a screening model for resistance modifying drugs: role of protein supplement

Broxterman, H. J., Kuiper, C. M., Schuurhuis, G. J., van der Hoeven, J. J. M., Pinedo, H. M. & Lankelma, J., 1987, In : Cancer Letters. 35, p. 87-95

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Dendritic cells of the mouse recognized by two monoclonal antibodies

Breel, M., Mebius, R. E. & Kraal, G., Nov 1987, In : European Journal of Immunology. 17, 11, p. 1555-9 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Development of an in vivo clonogenic cell assay for rat prostate metastatic tumor-R3327-MatLyLu

Geldof, A. A., Rao, B. R. & de Voogt, H. J., 1 Jun 1987, In : Urological Research. 15, 3, p. 139-144 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Doppler studies in the growth retarded fetus

Hackett, G. A., Campbell, S., Nicolaides, K. H. & Bilardo, C., 1 Jan 1987, In : British medical journal (Clinical research ed.). 294, 6572, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

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Double minute chromatin bodies in HL 60 leukemia cells sensitive and resistant to differentiation inducing agents

Schwartsmann, G., Madan, K., Hein, Y., Pinedo, H. M. & Leyva, A., 1987, In : Cell biology international reports. 11, p. 651-655

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Effect of pyrimidine nucleosides on body temperature of man and rabbit in relation to pharmacokinetic data

Peters, G. J., van Groeningen, C. J., Lauresse, E., Kraal, I., Leyva, A., Lankelma, J. & Pinedo, H. M., 1987, In : Pharmaceutical Research. 4, p. 113-119

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Effects of 434 MHz microwave hyperthermia applied to the rat in the region of the cervical spinal cord

Sminia, P., Haveman, J., Wondergem, J., van Dijk, J. D. & Lebesque, J. V., 1 Sep 1987, In : International journal of hyperthermia. 3, 5, p. 441-52 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Downloads (Pure)

Electrochemistry of platinum complexes. I. Polarographic reduction mechanism with reference to electrochemical detection

Elferink, F., Leeuwenkamp, O. R., Pinedo, H. M. & van der Vijgh, W. J. F., 1987, In : J. Electronal. Chem.. 238, p. 297-313

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