Find Research Outputs

Search concepts
Selected filters
1985

Studies on a possible relationship between alterations in the cytoskeleton and induction of heat shock protein synthesis in mammalian cells

Van Bergen En Henegouwen, P. M. P., Jordi, W. J. R. M., Dongen, G. V., Ramaekers, F. C. S., Amesz, H. & Linnemans, W. A. M., 1 Jan 1985, In : International journal of hyperthermia. 1, 1, p. 69-83 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

The absence of influence of acetylsolicylic acid (ASA) on the transient decreased in platelet counts observed after infusion of bleomycin and vinblastin

Verwey, J., Kester, D. M., Breet, W. P. M., Hillen, H. F. P. & Pinedo, H. M., 1985, In : European Journal of Cancer and Clinical Oncology. 21, p. 1471-1474

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Downloads (Pure)

The concentration of 5 phosphoribosyl l pyrophosphate in monolayer tumor cells and the effect of various pyrimidine

Peters, G. J., Laurensse, E., Leyva, A. & Pinedo, H. M., 1985, In : The international journal of biochemistry. 17, 1, p. 95-99

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Downloads (Pure)

The effect of cytomegalovirus infection on T lymphocytes after allogeneic bone marrow transplantation

Würsch, A. M., Gratama, J. W., Middeldorp, J. M., Nissen, C., Gratwohl, A., Speck, B., Jansen, J., D'Amaro, J., The, T. H. & De Gast, G. C., Nov 1985, In : Clinical and Experimental Immunology. 62, 2, p. 278-87 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

The pharmacology of 5' deoxy 5 fluorouridine in patients with resistant ovarian cancer

de Bruijn, E. A., van Oosterom, A. T., Tjaden, U. R., Reeuwijk, H. J. E. M. & Pinedo, H. M., 1985, In : Cancer Research. 45, p. 5931-5936

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Downloads (Pure)

Transsexuality in the Netherlands. Some medical and legal aspects

Kuiper, A. J., Cohen-Kettenis, P. T. & Van der Reyt, F., 1 Jan 1985, In : Medicine and Law. 4, 4, p. 373-378 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin K-dependent carboxylase: the carboxylation of exogenous substrates in different systems

de Boer-van den Berg, M. A. G., Ulrich, M. M. W., Hemker, H. C., Soute, B. A. M. & Vermeer, C., 20 Sep 1985, In : Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular. 831, 1, p. 94-98 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

1984

Changes in activities and isozyme patterns of glycolytic enzymes during erythroid differentiation in vitro

Nijhof, W., Wierenga, P. K., Staal, G. E. & Jansen, G., Sep 1984, In : Blood. 64, 3, p. 607-13 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Clinical and biochemical studies of high-dose thymidine treatment in patients with solid tumors

Leyva, A., Schornagel, J. H., Kraal, I. & Pinedo, H. M., 1984, In : Journal of Cancer Research and Clinical Oncology. 107, p. 211-216

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
30 Downloads (Pure)

Clinical experience with l,l-diamminomethyl-cyclohexane(sulphate)platinum (II) (TNO 6)

Vermorken, J. B., ten Bokkel Huinink, W. W., McVie, J. G., van der Vijgh, W. J. F. & Pinedo, H. M., 1984, Platinum Coordination Complexes in Cancer Chemotherapy. Martinus Nijhoff Publishers, p. 330-343

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Open Access
File
4 Downloads (Pure)

Combination chemotherapy with Cisplatin and VM 26 in advanced transitional cell carcinoma of the bladder

Stoter, G., van Oosterom, A. T., Mulder, J. H., de Pauw, M., Fossa, S. V. & Pinedo, H. M., 1984, In : European Journal of Cancer and Clinical Oncology. 20, 3, p. 315-317

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
27 Downloads (Pure)

Combination Chemotherapy with or without hexamethylmelamine in alkylating agent-resistant ovarian carcinoma

Neijt, J. P., ten Bokkel Huinink, W. W., van der Burg, M. E. L., van Oosterom, A. T., Kooyman, C. D., van Houwelingen, J. C. & Pinedo, H. M., 1984, In : Cancer. 53, 7, p. 1467-1472

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
27 Downloads (Pure)

Comparative studies on the heat-induced thermotolerance of protein synthesis and cell division in synchronized mouse neuroblastoma cells

Van Dongen, G., Van De Zande, L., Schamhart, D. & Van Wijk, R., 1 Jan 1984, In : International Journal of Radiation Biology. 46, 6, p. 759-769 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Current status of systemic chemotherapy in the treatment of advanced ovarian cancer with emphasis on CHAP-5

Neijt, J. P., ten Bokkel Huinink, W. W., [Unknown], U., van Oosterom, A. T., Vriesendorp, R. & Pinedo, H. M., 1984, In : Radiotherapy and Oncology. 2, p. 19-29

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
33 Downloads (Pure)

CYVADIC in advanced soft tissue sarcoma: A randomized study comparing two schedules

Pinedo, H. M., Bramwell, V. H. C., Mouridsen, H. T., Somers, R., Vendrik, C. P. J., Santoro, A., Buesa, J., Wagener, T., Oosterom, A. T., van Unnik, J. A. M., Sylvester, R., Pauw, M., Thomas, D. & Bonadonna, G., 1984, In : Cancer. 53, p. 1825-1832

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Downloads (Pure)

Detection of immunoglobulin M and G antibodies against cytomegalovirus early and late antigens by enzyme-linked immunosorbent assay

Middeldorp, J. M., Jongsma, J., ter Haar, A., Schirm, J. & The, T. H., Oct 1984, In : Journal of Clinical Microbiology. 20, 4, p. 763-71 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Determination of ethylenediamineplatinum (II) malonate in infusion fluids, human plasma and urine by high performance liquid chromatography

van der Vijgh, W. J. F., Elferink, F., Postma, G. J., Vermorken, J. B. & Pinedo, H. M., 1984, In : Journal of chromatography. 310, p. 335-342

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
26 Downloads (Pure)

Distribution of cardiac output, oxygen consumption and lactate production in canine endotoxin shock

van Lambalgen, A. A., Bronsveld, W., van den Bos, G. C. & Thijs, L. G., 1984, In : Cardiovascular Research. 18, 4, p. 195-205

Research output: Contribution to journalReview articleAcademicpeer-review

Feasibility study on daily administration of cis diammine-dichloroplatinum(II) in combination with radiotherapy (RTO 00027)

Keizer, H. J., Karim, A. B. M. F., Njo, K. H., Tierie, A. H., Snow, G. B., Vermorken, J. B. & Pinedo, H. M., 1984, In : Radiotherapy and Oncology. 1, 3, p. 227-234

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Downloads (Pure)

Fluctuations in phosphoribosyl pyrophosphate levels in monolayer tumor cell lines

Peters, G. J., Lauresse, E., Leyva, A. & Pinedo, H. M., 1984, In : FEBS Letters. 170, 2, p. 277-280

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
25 Downloads (Pure)

Glucose-6-phosphate isomerase deficiency-Nahariya: extreme in vitro and in vivo lability of the mutant enzyme

Rijksen, G., Jansen, G., Manaster, J., Ezekiel, E., Streichman, S. & Staal, G. E., Jun 1984, In : American Journal of the Medical Sciences. 20, 6, p. 529-34 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Importance of end-systolic volume for the evaluation of cardiac pump performance

Kerkhof, PL., 1984, p. 1339-1351. 13 p.

Research output: Contribution to conferencePaperAcademic

Influence of hydrolysis products of aqua(l,l-bis (aminomethyl) cyclohexane)-sulfatoplatinum(II) on toxicity in rats

Elferink, F., van der Vijgh, W. J. F., van der Poort, S. E. J. M., Henzen-Logmans, S. C. & Pinedo, H. M., 1984, In : Cancer Letters. 25, p. 61-69

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Downloads (Pure)

Lymph node involvement in a humoral immune response

Geldof, A. A., van der Ende, M. B. & Langevoort, H. L., 1 Jan 1984, In : The Anatomical Record. 209, 4, p. 541-546 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

MEDWISE: A MEDICAL DATA BASE FOR PERSONAL COMPUTERS.

Kerkhof, P. L. M., Helder, J., Van Dijke, C. P. H., Schreuder, J. J. A., Koops, H., Friederich, F. R. S., Camphuisen, G. & Gill, K., 1 Jan 1984, In : Automedica. 5, 4, p. 333-341 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Metabolism of 4' modified analogs of doxorubicin. Unique glucuronidation pathway for 4' epidoxorubicin

Weenen, H., van Maanen, J. M. S., de Planque, M. M., McVie, J. G. & Pinedo, H. M., 1984, In : European Journal of Cancer and Clinical Oncology. 20, 7, p. 919-926

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
28 Downloads (Pure)

Methotrexate with thymidine protection or rescue in advanced head and neck cancer. A phase II study

Schornagel, J. H., Leyva, A. & Pinedo, H. M., 1984, In : Cancer treatment reports. 68, p. 543-545

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Downloads (Pure)

Migration of specific antibody-forming cells during the secondary immune response against horseradish peroxidase

Geldof, A. A. & v.d. Ende, M. B., 1 Jan 1984, In : Virchows Archiv B Cell Pathology Including Molecular Pathology. 45, 1, p. 107-112 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Morphology, Kinetics and Secretory Activity of Antibody-forming Cells

Geldof, A. A., Rijnhart, P., Ende, M. V. D., Kors, N. & Langevoort, H. L., 1 Jan 1984, In : Immunobiology. 166, 3, p. 296-307 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pharmacokinetics of carminomycin in Man: Biweekly schedule vs single dose every three weeks

Weenen, H., Pinedo, H. M., de Planque, M. M., ten Bokkel Huinink, W. W., McVie, J. G. & Lankelma, J., 1984, In : European Journal of Cancer and Clinical Oncology. 20, 7, p. 915-918

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
24 Downloads (Pure)

Pharmacokinetics of free and total platinum species after short term infusion of cisplatin

Vermorken, J. B., van der Vijgh, W. J. F., Klein, I., Hart, A. A. M., Gall, H. E. & Pinedo, H. M., 1984, In : Cancer treatment reports. 68, 3, p. 505-513

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Downloads (Pure)

Presynaptic alpha 2- and postsynaptic beta-adrenoceptor sensitivity in slices of rat neocortex after chronic treatment with various antidepressant drugs

Schoffelmeer, A. N., Hoorneman, E. M., Sminia, P. & Mulder, A. H., Feb 1984, In : Neuropharmacology. 23, 2A, p. 115-9 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pyruvate kinase and the "high ATP syndrome"

Staal, G. E., Jansen, G. & Roos, D., Jul 1984, In : Journal of Clinical Investigation. 74, 1, p. 231-5 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Randomised trial comparing two combination chemotherapy regimens (Hexa CAF versus CHAP-5) in advanced ovarian carcinoma

Neijt, J. P., ten Bokkel Huinink, W. W., van der Burg, M. E. L., van Oosterom, A. T., Vriesendorp, R., Kooyman, C. D., van Lindert, A. C. M., Hamerlynck, J. V. T., van Houwelingen, J. C. & Pinedo, H. M., 1984, In : Lancet. 8403, p. 594-600

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Downloads (Pure)

Recovery from mitomycin C induced haemolytic uraemic syndrom, a case report

Verwey, J., Boven, E., van der Meulen, J. & Pinedo, H. M., 1984, In : Cancer. 54, p. 2878-2881

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Downloads (Pure)

Separation of 5 fluorouracil and uracil by ion pair reversed phase high performance liquid chromatography on a column with porous polymer packing

Peters, G. J., Kraal, I., Lauresse, E., Leyva, A. & Pinedo, H. M., 1984, In : Journal of chromatography. 307, p. 464-468

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Downloads (Pure)

Separation of several 5 fluorouracil metabolites in various melanoma cell lines. Evidence for the synthesis of 5 fluorouraci lnucleotide sugars

Peters, G. J., Laurensse, E., Lankelma, J., Leyva, A. & Pinedo, H. M., 1984, In : European Journal of Cancer and Clinical Oncology. 20, p. 1425-1431

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
27 Downloads (Pure)

The 5 year survival of patients with disseminated non seminomatous testicular cancer treated with cis platin vinblastine and bleomycin

Stoter, G., Vendrik, C. P. J., Struyvenberg, A., Sleyfer, D. T., Vriesendorp, R., Schraffordt Koops, H., van Oosterom, A. T., ten Bokkel Huinink, W. W. & Pinedo, H. M., 1984, In : Cancer. 54, 8, p. 1521-1524

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Downloads (Pure)

The vitamin K-dependent carboxylation of proteins

Vermeer, C., Soute, B. A. M., Ulrich, M., Hamulyák, K. & De Boer-van den Berg, M. A., 1 Jan 1984, In : Biochemical Society Transactions. 12, 6, p. 922-924 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Transexuality and psychotherapy

Cohen-Kettenis, P. & Kuiper, B., 1 Jan 1984, In : Tijdschrift voor psychotherapie. 10, 3, p. 153-166 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Ultrastructural and biochemical properties of oxygen-resistant Chinese hamster ovary cells

van der Valk, P., Gille, J. J., Oostra, A. B. & Joenje, H., Apr 1984, In : Journal of Cell Biology. 8, 4, p. 272

Research output: Contribution to journalArticleAcademicpeer-review

1983

An assessment of the relative validity of retrospective interviewing for measuring dietary intake

Van Leeuwen, F. E., De Vet, H. C. W., Hayes, R. B., Van Staveren, W. A., West, C. E. & Hautvast, J. G. A. J., 1 Jan 1983, In : American Journal of Epidemiology. 118, 5, p. 752-758 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

An in vitro system to study interactions between bacteria and epithelial cells at the molecular level

Middeldorp, J. M. & Witholt, B., Jan 1983, In : Journal of Medical Microbiology. 129, 1, p. 179-90 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

A stimulatory role for cytomegalovirus (CMV) antibodies in CMV-specific lymphocyte proliferation in vitro

Schirm, J., Middeldorp, J. M., Roenhorst, H. W. & The, T. H., 1983, In : Intervirology. 20, 2-3, p. 114-22 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Complete response of metastasized adrenal cortical carcinoma with o,p' DDD

Boven, E., Vermorken, J. B., van Slooten, H. & Pinedo, H. M., 1983, In : Cancer. 53, p. 26-29

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Downloads (Pure)

Daily cis-dichloro-diammine-platinum (II) as a ratio enhancer: A preliminary toxicity report

Pinedo, H. M., Karim, A. B. M. F., van Vliet, W. H. & Vermorken, J. B., 1983, In : Journal of Cancer Research and Clinical Oncology. 105, p. 79-82

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Downloads (Pure)

Destruction of murine lymphoma cells by allogeneic peritoneal macrophages in vitro: Influence of antiserum

Dingemans, K. P., Pels, E., Van Dongen, G. & Den Otter, W., 1 Jan 1983, In : Journal of the National Cancer Institute. 70, 1, p. 181-192 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Failure of 3-PPP to activate dopamine autoreceptors in vitro

Sminia, P. & Mulder, A. H., 22 Apr 1983, In : European Journal of Pharmacology. 89, 1-2, p. 183-4 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Glycolytic enzymes of an erythroleukemic cell line, K562, before and after hemoglobin induction

Jansen, G., Rijksen, G., de Gast, G. C. & Staal, G. E., Aug 1983, In : Experimental Hematology. 11, 7, p. 626-38 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Growth kinetics of human tumor cell line colonies in CMRL lob medium and in cell free ascites

Uitendaal, M. P., Pinedo, H. M., Kirkels, W., Hubers, H. A. J. M. & Herman, C. J., 1983, In : Int. J. Cell Cloning. 1, p. 271

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Downloads (Pure)