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1988

The pharmacokinetic plasma profile of mitomycin C, measured after sequential intermittent intravenous administration

Lankelma, J., Stuurman, M., van Hoogenhuijze, J., van Bochove, A., Vermorken, J. B., Verwey, J. & Pinedo, H. M., 1988, In : European Journal of Cancer and Clinical Oncology. 24, p. 175-180

Research output: Contribution to journalArticleAcademicpeer-review

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The quantification of gammacarboxyglutamic acid residues in plasma-osteocalcin

Soute, B. A. M., Ulrich, M. M. W., Knapen, M. H. J., van Haarlem, L. J. M. & Vermeer, C., 1 Sep 1988, In : Calcified Tissue International. 43, 3, p. 184-188 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

The role of oxygen-derived five radicals in the cytotoxicity of doxorubicin in multidrug resistant and sensitive human ovarian cancer cells

Cervantes, A., Pinedo, H. M., Lankelma, J. & Schuurhuis, G. J., 1988, In : Cancer Letters. 41, p. 169-177

Research output: Contribution to journalArticleAcademicpeer-review

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Vitamin K-dependent carboxylation. A synthetic peptide based upon the γ-carboxylation recognition site sequence of the prothrombin propeptide is an active substrate for the carboxylase in vitro

Ulrich, M. M. W., Furie, B. C., Jacobs, M. R., Vermeer, C. & Furie, B. C., 1 Jan 1988, In : Journal of Biological Chemistry. 263, 20, p. 9697-9702 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin K is no antagonist for the action of warfarin in rat osteosarcoma UMR 106

Ulrich, M. M. W., Knapen, M. H. J., Herrmann Erlee, M. P. M. & Vermeer, C., 1 Apr 1988, In : Thrombosis Research. 50, 1, p. 27-32 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

1987

9-Amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease, inhibits acetylcholinesterase activity and slow outward K+ current

Drukarch, B., Kits, K. S., Van der Meer, E. G., Lodder, J. C. & Stoof, J. C., 2 Sep 1987, In : European Journal of Pharmacology. 141, 1, p. 153-7 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Absorption of epi doxorubicin after administration in patients with in situ transitional cell carcinoma of the bladder

Mross, K., Maessen, P., van der Vijgh, W. J. F., Bogdanowicz, J. F., Kurth, K. H. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology. 23, 3, p. 505-508

Research output: Contribution to journalArticleAcademicpeer-review

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Adriamycin versus Epirubicin in ancced soft tissue sarcomas. A randomized phase II/phase III study of the EORTC Soft Tissue and Bone Sarcoma Group

Mouridsen, H. T., Bastholt, L., Somers, R., Santoro, A., Bramwell, V., Mulder, J. H., van Oosterom, A. T., Buesa, J., Pinedo, H. M., Thomas, D. & Sylvester, R., 1987, In : European Journal of Cancer and Clinical Oncology.

Research output: Contribution to journalArticleAcademicpeer-review

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Analysis of human ascites effect on clonogenic growth of human tumor cell lines and NRK 49F cells in soft agar

Broxterman, H. J., Sprenkels-Schotte, C., Engelen, P., Leyva, A. & Pinedo, H. M., 1987, In : Int. J. Cell Cloning. 5, p. 158-169

Research output: Contribution to journalArticleAcademicpeer-review

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Androgen action blockade does not result in reduction in size but changes histology of the normal human prostate

De Voogt, H. J., Rao, B. R., Geldof, A. A., Gooren, L. J. G. & Bouman, F. G., 1 Jan 1987, In : The Prostate. 11, 4, p. 305-311 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

A phase II study of carboplatin in advance d or metastatic stomach cancer

Beer, M., Cavalli, F., Kaye, S. B., Lev, L. L., Clavel, M., Smyth, J., van Glabbeke, M., Renard, J. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology.

Research output: Contribution to journalArticleAcademicpeer-review

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A sensitive, non radiometric assay for dihyroorotic acid de hydrogenase using anion exchange high performance liquid chromatogra phy

Peters, G. J., Laurensse, E., Leyva, A. & Pinedo, H. M., 1987, In : Analytical Biochemistry. 161, p. 32-38

Research output: Contribution to journalArticleAcademicpeer-review

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A sensitive enzyme-linked immunosorbent assay for the detection of herpes simplex virus antigens

Middeldorp, J. M., Hooymans, A. M., Kocken, A. J., van Loon, A. M., Emsbroek, J. A. & Coutinho, R. A., Aug 1987, In : Journal of Virological Methods. 17, 1-2, p. 159-74 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Authors' Reply

Hackett, G. A., Campbell, S., Nicolaides, K. H. & Bilardo, C., 1 Jan 1987, In : British medical journal (Clinical research ed.). 294, 6572, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

Chemical reactivity of cisplatin bound to human plasma proteins

Hegedus, L., van der Vijgh, W. J. F., Klein, I., Kerper Fronius, S. & Pinedo, H. M., 1987, In : Cancer Chemotherapy and Pharmacology. 20, p. 211-212

Research output: Contribution to journalArticleAcademicpeer-review

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Chemotherapy of advanced soft tissue sarcomas in adults

Pinedo, H. M. & Kenis, Y., 1987, In : Cancer Treatment Reviews. 4, 2, p. 67-86

Research output: Contribution to journalArticleAcademicpeer-review

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Clinical trials in advanced breast cancer

Schwartsmann, G. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology. 23, 6, p. 595-597

Research output: Contribution to journalArticleAcademicpeer-review

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Comparative pharmacokinetics of cisplatin and three analogs in mice and man

van Hennik, M. B., van der Vijgh, W. J. F., Klein, I., Elferink, F., Vermorken, J. B., Winograd, B. & Pinedo, H. M., 1987, In : Cancer Research. 47, p. 6297-6301

Research output: Contribution to journalArticleAcademicpeer-review

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Cytochrome P 450 mediated O-demethylation: a route in the metabolic activation of etoposide (VP 16 213)

van Maanen, J. M. S., de Vries, J., Pappie, D., van den Akker, E., Lafleur, M. V. M., Retel, J., van der Greef, J. & Pinedo, H. M., 1987, In : Cancer Research. 47, p. 4658-4662

Research output: Contribution to journalArticleAcademicpeer-review

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Daunomycin accumulation in resistant tumor cells as a screening model for resistance modifying drugs: role of protein supplement

Broxterman, H. J., Kuiper, C. M., Schuurhuis, G. J., van der Hoeven, J. J. M., Pinedo, H. M. & Lankelma, J., 1987, In : Cancer Letters. 35, p. 87-95

Research output: Contribution to journalArticleAcademicpeer-review

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Dendritic cells of the mouse recognized by two monoclonal antibodies

Breel, M., Mebius, R. E. & Kraal, G., Nov 1987, In : European Journal of Immunology. 17, 11, p. 1555-9 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Development of an in vivo clonogenic cell assay for rat prostate metastatic tumor-R3327-MatLyLu

Geldof, A. A., Rao, B. R. & de Voogt, H. J., 1 Jun 1987, In : Urological Research. 15, 3, p. 139-144 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Doppler studies in the growth retarded fetus

Hackett, G. A., Campbell, S., Nicolaides, K. H. & Bilardo, C., 1 Jan 1987, In : British medical journal (Clinical research ed.). 294, 6572, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

Double minute chromatin bodies in HL 60 leukemia cells sensitive and resistant to differentiation inducing agents

Schwartsmann, G., Madan, K., Hein, Y., Pinedo, H. M. & Leyva, A., 1987, In : Cell biology international reports. 11, p. 651-655

Research output: Contribution to journalArticleAcademicpeer-review

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Effect of pyrimidine nucleosides on body temperature of man and rabbit in relation to pharmacokinetic data

Peters, G. J., van Groeningen, C. J., Lauresse, E., Kraal, I., Leyva, A., Lankelma, J. & Pinedo, H. M., 1987, In : Pharmaceutical Research. 4, p. 113-119

Research output: Contribution to journalArticleAcademicpeer-review

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Effects of 434 MHz microwave hyperthermia applied to the rat in the region of the cervical spinal cord

Sminia, P., Haveman, J., Wondergem, J., van Dijk, J. D. & Lebesque, J. V., 1 Sep 1987, In : International journal of hyperthermia. 3, 5, p. 441-52 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Electrochemistry of platinum complexes. I. Polarographic reduction mechanism with reference to electrochemical detection

Elferink, F., Leeuwenkamp, O. R., Pinedo, H. M. & van der Vijgh, W. J. F., 1987, In : J. Electronal. Chem.. 238, p. 297-313

Research output: Contribution to journalArticleAcademicpeer-review

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EUROFIT - European test of physical fitness

Adam, C., Klissouras, V., Ravazzolo, M., Renson, R., Tuxworth, W., Kemper, HCG., van Mechelen, W., Hlobil, H., Beunen, G. & Levarlet-Joye, H., 1987, 1 ed. Rome: Council of Europe.

Research output: Book/ReportBookAcademicpeer-review

Extraction of osteocalcin from fossil bones and teeth

Ulrich, M. M. W., Perizonius, W. R. K., Spoor, C. F., Sandberg, P. & Vermeer, C., 16 Dec 1987, In : Biochemical and Biophysical Research Communications. 149, 2, p. 712-719 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hoe kunnen sportblessures voorkomen worden: NISGZ publicatie nummer 25

van Mechelen, W., Hlobil, H. & Kemper, HCG., Jan 1987, Oosterbeek.

Research output: Book/ReportBookAcademicpeer-review

Improved method for the determination of 4' epidoxorubicin and seven metabolites in plasma by high performance liquid chromatography

Maessen, P. A., Pinedo, H. M., Mross, K. B. & van der Vijgh, W. J. F., 1987, In : j. chromat. biomed.. 417, p. 339-346

Research output: Contribution to journalArticleAcademicpeer-review

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Isolation and partial characterization of a vitamin K-dependent carboxylase from bovine aortae.

Van Haarlem, L. J., Ulrich, M. M., Hemker, H. C., Soute, B. A. & Vermeer, C., 1 Jan 1987, In : The Biochemical journal. 245, 1, p. 251-255 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

MATERNAL OXYGEN THERAPY FOR INTRAUTERINE GROWTH RETARDATION

Nicolaides, K. H., Bradley, R. J., Soothill, P. W., Campbell, S., Bilardo, C. M. & Gibb, D., 1987, In : The Lancet. 329, 8539, p. 942-945

Research output: Contribution to journalArticleAcademicpeer-review

Metabolism of epidoxorubicin in animals: absence of glucuronidation

Maessen, P. A., Mross, K. B., Pinedo, H. M. & van der Vijgh, W. J. F., 1987, In : Cancer Chemotherapy and Pharmacology. 20, p. 85-87

Research output: Contribution to journalArticleAcademicpeer-review

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Mitomycin C induced haemolytic uremic syndrome. Six case reports and review of the literature on renal , pulmonal and cardiac side effects of the drug

Verwey, J., van der Burg, M. E. L. & Pinedo, H. M., 1987, In : Radiotherapy and Oncology. 8, p. 33-42

Research output: Contribution to journalArticleAcademicpeer-review

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Mitomycin C induced renal toxicity, a dose dependent side effect?

Verwey, J., de Vries, J. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology. 23, 2, p. 195-199

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Morphometric study of myocardial changes during puromycin aminonucleoside induced nephropathy in rats

van der Vijgh, W. J. F., van Velzen, D., van der Poort, S. E. J. M., Schlüper, H. M. M., Mross, K., Feyen, J. & Pinedo, H. M., 1987, In : Anticancer Research. 7, p. 1111-1116

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No evidence for involvement of plasma proteins or blood-borne cells in amyloid plaque formation in scrapie-affected mice - An immunohistoperoxidase study

Eikelenboom, P., Scott, J. R., McBride, P. A., Rozemuller, J. M., Bruce, M. E. & Fraser, H., 1 Dec 1987, In : Virchows Archiv B Cell Pathology Including Molecular Pathology. 53, 1, p. 251-256 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Persistence of encephalitogenic arboviruses in brain cell culture. Brief report

Amor, S. & Webb, H. E., 1987, In : Archives of virology. 97, 3-4, p. 373-7 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pharmacokinetics of diammine(l,l cyclobutanedi carboxylato) platinum(II) (carboplatin) after intravenous administration

Elferink, F., van der Vijgh, W. J. F., Klein, I., Vermorken, J. B., Gall, H. E. & Pinedo, H. M., 1987, In : Cancer treatment reports. 71, p. 1231-1237

Research output: Contribution to journalArticleAcademicpeer-review

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Pharmacoki netics of ethylenediaminemalonatoplatinum (II) (JM 4O) during phase I Trial

Elferink, F., van der Vijgh, W. J. F., ten Bokkel Huinink, W. W., Vermorken, J. B., Klein, I., Winograd, B., Knobf, M. K. T., Simonetti, G., Gall, H. E., McVie, J. G. & Pinedo, H. M., 1987, In : British Journal of Cancer. 56, p. 479-483

Research output: Contribution to journalArticleAcademicpeer-review

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Phase II study of iproplatin (CHIP, JM 9) in advanced squamous cell carcinoma of the head and neck

Abele, R., Clavel, M., Monfardini, M., Bruntsch, U., Renard, J., van Glabbeke, M. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology. 23, p. 387-389

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Phase II trial of combined radiotherapy and daily low-dose cisplatin for inoperable, locally advanced non small cell lung cancer

van Harskamp, G., Boven, E., Vermorken, J. B., van Deutekom, H., Stam, J., Njo, K. H., Karim, A. B. M. F., Tierie, A. H., Golding, R. P. & Pinedo, H. M., 1987, In : International Journal of Radiation Oncology Biology Physics. 13, p. 1735-1738

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Phase II trial of menogaril in advanced malignant melanoma

Gundersen, S., Monfardini, S., Renard, G., van Glabbeke, M. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology. 23, 11, p. 1707-1708

Research output: Contribution to journalArticleAcademicpeer-review

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Potentiation of doxorubicin cytotoxicity by the calcium antagonist bepridil in anthracycline resistant and sensitive cell lines. A comparison with verapamil

Schuurhuis, G. J., Broxterman, H. J., van der Hoeven, J. M., Pinedo, H. M. & Lankelma, J., 1987, In : Cancer Chemotherapy and Pharmacology. 20, p. 285-290

Research output: Contribution to journalArticleAcademicpeer-review

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Prospective study on the dose relationship of mitomycin C induced interstitial pneumonitis

Verwey, J., van Zanten, T., Souren, T., Golding, R. & Pinedo, H. M., 1987, In : Cancer. 60, p. 756

Research output: Contribution to journalArticleAcademicpeer-review

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Purine nucleosides as cell specific modulators of 5 fluoro uracil metabolism and cytotoxicity

Peters, G. J., Laurensse, E., [Unknown], E., Pinedo, H. M. & Lankelma, J., 1987, In : European Journal of Cancer and Clinical Oncology. 23, p. 1869-1881

Research output: Contribution to journalArticleAcademicpeer-review

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Relationship between clinical parameters and pharmacokinetics of mitomycin C

Verwey, J., den Hartigh, J., Stuurman, M., de Vries, J. & Pinedo, H. M., 1987, In : Journal of Cancer Research and Clinical Oncology. 113, p. 91-94

Research output: Contribution to journalArticleAcademicpeer-review

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Renewal timing of long‐acting depot luteinizing hormone‐releasing hormone agonist (Zoladex) is critical in the treatment of hormone‐dependent rat prostatic carcinoma (R3327‐H)

Geldof, A. A., De Voogt, H. J. & Rao, B. R., 1 Jan 1987, In : The Prostate. 11, 3, p. 281-290 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Resistance of HL 60 promyelocytic leukemia cells to induction of differentiation and its reversal by combination treatment

Schwartsmann, G., Pinedo, H. M. & Leyva, A., 1987, In : European Journal of Cancer and Clinical Oncology. 23, 6, p. 739-743

Research output: Contribution to journalArticleAcademicpeer-review

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