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1986

Direct effects of chemotherapeutic agents on rat prostate tumor clonogenic cells

Geldof, A. A., Rao, B. R. & De Voogt, H. J., 1 Jan 1986, In : Anticancer Research. 6, 4, p. 837-840 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effect of serum on heat response of synchronized mouse neuroblastoma cells: Protection of cell cycle progression, protein synthesis and survival

Van Dongen, G. & Van Wijk, R., 1 Jan 1986, In : International Journal of Radiation Biology. 50, 1, p. 77-91 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

10 Downloads (Pure)

Enhanced trans-plantability of human ovarian cancer lines in cyclophosphamide pretreated nude mice

Nauta, M. M., Boven, E., Schlüper, H. M. M., Erkelens, C. A. M. & Pinedo, H. M., 1986, In : British Journal of Cancer. 54, p. 331-335

Research output: Contribution to journalArticleAcademicpeer-review

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Free radical formation from the antineoplastic agent VP 16 213

van Maanen, J. M. S., de Ruiter, C., Kootstra, P. R., de Vries, J. & Pinedo, H. M., 1986, In : Free radical research. 1, 4, p. 263-272

Research output: Contribution to journalArticleAcademicpeer-review

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Glycolytic activity in human red cell populations separated by a combination of density and counterflow centrifugation. Evidence for an improved separation of red cells according to age

Jansen, G., Hepkema, B. G., van der Vegt, S. G. & Staal, G. E., Sep 1986, In : Scandinavian journal of haematology. 37, 3, p. 189-95 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Growth inhibitory effects of 5 aza 2'-doxycytidine in HL 60 promyelocytic leukemia cells resistant to differentation induction

Leyva, A., Schwartsmann, G., Boeije, L. C. M., Pinedo, H. M. & de Waal, F., 1986, In : Biophys. Biochem. Res. Commun.. 141, p. 629-635

Research output: Contribution to journalArticleAcademicpeer-review

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Heart-mechanical assist device interaction.

Kresh, J. Y., Kerkhof, P. L., Goldman, S. M. & Brockman, S. K., 1 Jul 1986, In : ASAIO transactions / American Society for Artificial Internal Organs. 32, 1, p. 437-443 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Immunofluorescence for detection of antibodies against human cytomegalovirus-induced membrane antigens

Middeldorp, J. M., Jongsma, J. & The, T. H., Sep 1986, In : Journal of Clinical Microbiology. 24, 3, p. 405-13 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Increase of thermoresistance after growth stimulation of resting Reuber H35 hepatoma cells. Alteration of nuclear characteristics, non-histone chromosomal protein phosphorylation and basal heat shock protein synthesis

Van Dongen, G., Geilenkirchen, W. L. M., Van Rijn, J. & Van Wijk, R., 1 Jan 1986, In : Experimental Cell Research. 166, 2, p. 427-441 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interaction of cisplatin and carboplatin with sodium thiosulphate: reaction rates and protein binding

Elferink, F., van der Vijgh, W. J. F., Klein, I. & Pinedo, H. M., 1986, In : the Journal of Applied Laboratory Medicine. 32, 4, p. 641-645

Research output: Contribution to journalArticleAcademicpeer-review

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Killing of human cytomegalovirus-infected fibroblasts by antiviral antibody and complement

Middeldorp, J. M., Jongsma, J. & The, T. H., Jan 1986, In : Journal of Infectious Diseases. 153, 1, p. 48-55 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

9 Downloads (Pure)

Modulation of cytotoxicity and metabolism of 5 fluorouracil in two intestine cell lines

Peters, G. J., Laurensse, E. J., Leyva, A. & Pinedo, H. M., 1986, In : Advances in Experimental Medicine and Biology. 195B, p. 113-120

Research output: Contribution to journalArticleAcademicpeer-review

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Monoclonal antibodies in cancer treatment: where do we stand after ten years?

Boven, E. & Pinedo, H. M., 1986, In : Radiotherapy and Oncology. 5, p. 109-117

Research output: Contribution to journalArticleAcademicpeer-review

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Naar een registratiesysteem van sportblessures in Nederland: NISGZ publicatie nr. 24

Schlatmann, Hlobil, H., van Mechelen, W. & Kemper, HCG., Oct 1986

Research output: Book/ReportBookAcademicpeer-review

Neonatal screening for cystic fibrosis

Dankert-Roelse, J. E., Meerman, G. J., Cornel, M. C., Knol, K. & ten Kate, L. P., 8 Oct 1986, In : Lancet. 1, 8484, p. 802-803 2 p.

Research output: Contribution to journalLetterAcademicpeer-review

NEONATAL SCREENING FOR CYSTIC FIBROSIS

Dankert-Roelse, J. E., Te Meerman, G. J., Cornel, M. C., Knol, K. & Ten Kate, L. P., 5 Apr 1986, In : The Lancet. 327, 8484, p. 802-803 2 p.

Research output: Contribution to journalLetterAcademicpeer-review

8 Downloads (Pure)

On line differential pulse polarographic detection of carboplatin in biological samples after chromatographic separation

Elferink, F., van der Vijgh, W. J. F. & Pinedo, H. M., 1986, In : Analytical Chemistry. 58, p. 2293-2296

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Pharmacokinetic comparison of cisplatin in solution with common lyophilized cisplatinum (PlatinolR)

Vermorken, J. B., van der Vijgh, W. J. F., Klein, I., Gall, H. E., Splinter, T. A. W., Hart, A. A. M. & Pinedo, H. M., 1986, In : Therapeutic Drug Monitoring. 8, p. 264-268

Research output: Contribution to journalArticleAcademicpeer-review

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Pharmacokinetics of free and total platinum species following rapid and prolonged infusions of cisplatin

Vermorken, J. B., van der Vijgh, W. J. F., Klein, I., Gall, H. E., van Groeningen, C. J., Hart, A. A. M. & Pinedo, H. M., 1986, In : Clinical Pharmacology & Therapeutics. 39, 2, p. 136-144

Research output: Contribution to journalArticleAcademicpeer-review

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Phase I and pharmacokinetic study of 5 aza2' deoxycytidine (NSC 127716) in cancer patients

van Groeningen, C. J., Leyva, A., O'Brien, A. M. P., Gall, H. E. & Pinedo, H. M., 1986, In : Cancer Research. 46, p. 4831-4836

Research output: Contribution to journalArticleAcademicpeer-review

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8 Downloads (Pure)

Phase II study of 5' deoxy 5 fluorouridine (doxifluridine) in advanced malignant melanoma

Alberto, P., Rozencweig, M., Clavel, M., Siegenthaler, P., Cavalli, F., Gundersen, S., Bruntsch, U., Renard, J. & Pinedo, H. M., 1986, In : Cancer Chemotherapy and Pharmacology. 16, p. 78-79

Research output: Contribution to journalArticleAcademicpeer-review

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Phase II study of ifosfamide + adriamycine in advanced soft tissue sarcoma in adults. A preliminary analysis

Dombernowsky, P., Mouridsen, H. T., Schutte, J., Santoro, A., Roussé, J., Somers, R., Stewart, W., Pinedo, H. M., van Oosterom, A. T., Blackl edge, G., Thomas, D. & Sylvester, R., 1986, In : Cancer Chemotherapy and Pharmacology. 18, p. 17

Research output: Contribution to journalArticleAcademicpeer-review

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Phase I study of ethylenediamine platinum (II) malonate, JM 40 (NSC 146 068), a second generation platinum analog

Winograd, B., Vermorken, J. B., ten Bokkel Huinink, W. W., Simonetti, G., Gall, H. E., Knobf, M. K., van der Vijgh, W. J. F., McVie, J. G. & Pinedo, H. M., 1986, In : Cancer Research. 46, p. 2148-2151

Research output: Contribution to journalArticleAcademicpeer-review

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Primary resistance of renal adenocarcinoma to 1,2,4 triglycidylurazol (TGU, NSC 332488), a new triexpoxide cytostatic agent phase II study of the EORTC Early Clinical Trials Group

Bruntsch, U., Dodion, P., ten Bokkel Huinink, W. W., Hansen, H. H., Pinedo, H. M., Hansen, M., Renard, J. & van Glabbeke, M., 1986, In : European Journal of Cancer and Clinical Oncology. 22, 6, p. 697-699

Research output: Contribution to journalArticleAcademicpeer-review

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Randomized trials in soft tissue sarcomas in adults

Verwey, J. & Pinedo, H. M., 1986, Randomized trials in Cancer: A critical review by sites. Raven Press, p. 569-583

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Open Access
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RELATION OF FETAL HYPOXIA IN GROWTH RETARDATION TO MEAN BLOOD VELOCITY IN THE FETAL AORTA

Soothill, P., Bilardo, C. M., Nicolaides, K. & Campbell, S., 1986, In : The Lancet. 328, 8516, p. 1118-1120

Research output: Contribution to journalArticleAcademicpeer-review

2 Downloads (Pure)

Review: Development of new anti cancer drugs

Pinedo, H. M., 1986, In : Medical oncology and tumor pharmacotherapy. 3, 2, p. 63-69

Research output: Contribution to journalArticleAcademicpeer-review

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Sensitivity of human, murine and rat cells to 5 fluorouracil and 5'deoxy 5 fluorouridine in relation to drug metabolizing enzymes

Peters, G. J., Laurensse, E., Leyva, A., Lankelma, J. & Pinedo, H. M., 1986, In : Cancer Research. 46, p. 20-28

Research output: Contribution to journalArticleAcademicpeer-review

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Superior efficacy of trimelamol to hexamethylmelamine in human ovarian cancer xenografts

Boven, E., Nauta, M. M., Schlüper, H. M. M., Erkelens, C. A. M. & Pinedo, H. M., 1986, In : Cancer Chemotherapy and Pharmacology. 18, p. 124-128

Research output: Contribution to journalArticleAcademicpeer-review

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The cold pressor test during radionuclide ventriculography: a feasibility study in cancer patients

Verwey, J., van Lingen, A., Teule, J. J., Heidendal, G. A. K. & Pinedo, H. M., 1986, In : Medical oncology and tumor pharmacotherapy. 3, p. 11-14

Research output: Contribution to journalArticleAcademicpeer-review

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The difference in pharmacokinetics of Mitomycin C, given either as single agent or as a part of combination chemotherapy

Verwey, J., Stuurman, M., de Vries, J. & Pinedo, H. M., 1986, In : Journal of Cancer Research and Clinical Oncology. 112, p. 283-284

Research output: Contribution to journalArticleAcademicpeer-review

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The effect of microgravity on plasma-osteocalcin

Vermeer, C. & Ulrich, M. M. W., 1 Jan 1986, In : Advances in Space Research. 6, 12, p. 139-142 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

The EUROCAT-registration of congenital anomalies and multiple births. Aims, methods and results of the Dutch register in the period 1981-1983

Cornel, M. C., Swagemakers, M. L. S. & Te Meerman, G. J., 1 Jan 1986, In : Nederlands Tijdschrift voor Geneeskunde. 130, 27, p. 1233-1237 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

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The treatment of soft tissue sarcomas with focus on chemotherapy, a review

Pinedo, H. M. & Verwey, J., 1986, In : Radiotherapy and Oncology. 5, p. 193-205

Research output: Contribution to journalArticleAcademicpeer-review

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The vitamin k-antagonism of salicylate and warfarin

Roncaglioni, M. C., Ulrich, M. M. W., Muller, A. D., Soute, B. A. M., de Boer-van den Berg, M. A. G. & Vermeer, C., 15 Jun 1986, In : Thrombosis Research. 42, 6, p. 727-736 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Tissue homogenization using a micro-dismembrator for the measurement of enzyme activities

Peters, G. J., Laurensse, E. J., Leyva, A. & Pinedo, H. M., 1986, In : Clinica Chimica Acta. 158, p. 193-198

Research output: Contribution to journalArticleAcademicpeer-review

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Toxicity and antitumor effect of 5 fluorouracil and its rescue by uridine

Peters, G. J., van Dijk, J., van Groeningen, C. J., Laurensse, E. J., Leyva, A., Lankelma, J. & Pinedo, H. M., 1986, In : Advances in Experimental Medicine and Biology. 195B, p. 121-128

Research output: Contribution to journalArticleAcademicpeer-review

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Use of CI-920 in the characterization of the methotrexate transport defects in a resistant human leukemic CCRF-CEM cell line

Jansen, G., Schornagel, J. H., Rijksen, G. & de Gier, J., 1986, In: "Chemistry and Biology of Pteridines". Cooper, B. A. & Whitehead, V. M. (eds.). Walter de Gruyter, p. 543-546 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

Use of N-acetylethyleneimine [AEI] for the inactivation of Semliki Forest virus in vitro

Amor, S. & Webb, H. E., Aug 1986, In : Journal of Medical Virology. 19, 4, p. 367-76 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Validation of two running tests as estimates of maximal aerobic power in children

van Mechelen, W., Hlobil, H. & Kemper, H. C., 1986, In : European journal of applied physiology and occupational physiology. 55, 5, p. 503-6 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin K and the urogenital tract

Vermeer, C., Soute, B. A. M., Ulrich, M. M. W. & Van De Loo, P. G. F., 1 Jan 1986, In : Haemostasis. 16, 3-4, p. 246-257 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

1987

9-Amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease, inhibits acetylcholinesterase activity and slow outward K+ current

Drukarch, B., Kits, K. S., Van der Meer, E. G., Lodder, J. C. & Stoof, J. C., 2 Sep 1987, In : European Journal of Pharmacology. 141, 1, p. 153-7 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Absorption of epi doxorubicin after administration in patients with in situ transitional cell carcinoma of the bladder

Mross, K., Maessen, P., van der Vijgh, W. J. F., Bogdanowicz, J. F., Kurth, K. H. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology. 23, 3, p. 505-508

Research output: Contribution to journalArticleAcademicpeer-review

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Adriamycin versus Epirubicin in ancced soft tissue sarcomas. A randomized phase II/phase III study of the EORTC Soft Tissue and Bone Sarcoma Group

Mouridsen, H. T., Bastholt, L., Somers, R., Santoro, A., Bramwell, V., Mulder, J. H., van Oosterom, A. T., Buesa, J., Pinedo, H. M., Thomas, D. & Sylvester, R., 1987, In : European Journal of Cancer and Clinical Oncology.

Research output: Contribution to journalArticleAcademicpeer-review

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Analysis of human ascites effect on clonogenic growth of human tumor cell lines and NRK 49F cells in soft agar

Broxterman, H. J., Sprenkels-Schotte, C., Engelen, P., Leyva, A. & Pinedo, H. M., 1987, In : Int. J. Cell Cloning. 5, p. 158-169

Research output: Contribution to journalArticleAcademicpeer-review

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Androgen action blockade does not result in reduction in size but changes histology of the normal human prostate

De Voogt, H. J., Rao, B. R., Geldof, A. A., Gooren, L. J. G. & Bouman, F. G., 1 Jan 1987, In : The Prostate. 11, 4, p. 305-311 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

8 Downloads (Pure)

A phase II study of carboplatin in advance d or metastatic stomach cancer

Beer, M., Cavalli, F., Kaye, S. B., Lev, L. L., Clavel, M., Smyth, J., van Glabbeke, M., Renard, J. & Pinedo, H. M., 1987, In : European Journal of Cancer and Clinical Oncology.

Research output: Contribution to journalArticleAcademicpeer-review

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A sensitive, non radiometric assay for dihyroorotic acid de hydrogenase using anion exchange high performance liquid chromatogra phy

Peters, G. J., Laurensse, E., Leyva, A. & Pinedo, H. M., 1987, In : Analytical Biochemistry. 161, p. 32-38

Research output: Contribution to journalArticleAcademicpeer-review

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A sensitive enzyme-linked immunosorbent assay for the detection of herpes simplex virus antigens

Middeldorp, J. M., Hooymans, A. M., Kocken, A. J., van Loon, A. M., Emsbroek, J. A. & Coutinho, R. A., Aug 1987, In : Journal of Virological Methods. 17, 1-2, p. 159-74 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Authors' Reply

Hackett, G. A., Campbell, S., Nicolaides, K. H. & Bilardo, C., 1 Jan 1987, In : British medical journal (Clinical research ed.). 294, 6572, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review