Find Research Outputs

1990

A new method for automatic recognition of the radiographic trabecular pattern

Geraets, W. G. M., van der Stelt, P. F., Netelenbos, C. J. & Elders, P. J. M., 1990, In : Journal of Bone and Mineral Research. 5, 3, p. 227-233

Research output: Contribution to journalArticleAcademicpeer-review

Antitumor activity of brequinar sodium (Dup-785) against human head and neck squanmous cell carcinoma xenografts

Braakhuis, B. J. M., van Dongen, G. A. M. S., Peters, G. J., van Walsum, M. & Snow, G. B., 1 Jan 1990, In : Cancer Letters. 49, 2, p. 133-137 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Association between ovulation stimulation, in vitro fertilisation, and neural tube defects?

Cornel, M. C., ten Kate, L. P. & te Meerman, G. J., 1 Jan 1990, In : Teratology. 42, 3, p. 201-203 3 p.

Research output: Contribution to journalLetterAcademicpeer-review

Biosynthetic response of mouse intermediate pituitary gland to induced drinking and dehydration

Leenders, H. J., De Vries, T. J., Loop, V. D. F. T. L. & Jenks, B. G., 1 Jan 1990, In : Acta Endocrinologica. 122, 4, p. 527-534 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Characterization of receptor-mediated (anti)folate uptake in human CCRF-CEM cells

Westerhof, G. R., Jansen, G., Kathmann, G. A. M., Schornagel, J. H. & Rijksen, G., 1990, In: "Chemistry and Biology of Pteridines". Curtius, H. C., Ghisla, S. & Blau, N. (eds.). Walter de Gruyter, p. 1284-1287 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

16 Downloads (Pure)

Comparative metabolism and pharmacokinetics of doxorubicin and 4'-epidoxorubicin in plasma, heart and tumor of tumor-bearing mice

van der Vijgh, W. J. F., Maessen, P. A. & Pinedo, H. M., 1990, In : Cancer Chemotherapy and Pharmacology. 26, p. 9-12

Research output: Contribution to journalArticleAcademicpeer-review

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Comparative study of the sensitivity of head and neck cell lines to methotrexate (MTX) and the analog 10-ethyl, 10-deazaaminopterin (10-EdAM)

Brown, D. H., Braakhuis, B. J. M., Van Dongen, G. A. M. S. & Snow, G. B., 1 Jan 1990, In : Otolaryngology - Head and Neck Surgery. 102, 1, p. 20-25 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Conditietests

Geijsel, J., Hlobil, H. & van Mechelen, W., 1990, 1 ed. Utrecht/Antwerpen: uitgeverij Kosmos.

Research output: Book/ReportBookAcademicpeer-review

Cyclosporin A and Verapamil have different effects on energy metabolism in multidrug-resistant tumor cells

Broxterman, H. J., Pinedo, H. M., Schuurhuis, G. J. & Lankelma, J., 1990, In : British Journal of Cancer. 62, p. 85-88

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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D-2 dopamine autoreceptor selective drugs: do they really exist?

Drukarch, B. & Stoof, J. C., 1990, In : Life Sciences. 47, 5, p. 361-76 16 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Dangers of dietary germanium supplements

van der Spoel, J. I., Stricker, B. H. C., Esseveld, M. R. & Schipper, M. E. I., 14 Jul 1990, In : The Lancet. 336, 8707, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

Diagnostic significance of gadolinium-DTPA (diethylenetriamine penta-acetic acid) enhanced magnetic resonance imaging in thrombolytic treatment for acute myocardial infarction: Its potential in assessing reperfusion

Van Der Wall, E. E., Van Dijkman, P. R. M., De Roos, A., Doornbos, J., Van Der Laarse, A., Manger Cats, V., Van Voorthuisen, A. E., Matheijssen, N. A. A. & Bruschke, A. V. G., 1 Jan 1990, In : British Heart Journal. 63, 1, p. 12-17 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Differential presynaptic inhibition of neurotransmitter release as a functional implication of different opioid receptor types in the brain

Mulder, A. H., Heyna, M. H., de Vries, T. J., Frankhuyzen, A. L. & Schoffelmeer, A. N. M., 6 Jul 1990, In : European Journal of Pharmacology. 183, 6, p. 2072-2073 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Downloads (Pure)

Differential sensitivity of multidrug resistant and sensitive cells to resistance modifying agents and the relation with reversal of anthracycline resistance

Schuurhuis, G. J., Broxterman, H. J., Kuiper, C. M., Pinedo, H. M. & Lankelma, J., 1990, In : International Journal of Cancer. 46, p. 330-336

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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10 Downloads (Pure)

Differential sensitivity of multidrug resistant and sensitive cells to resistance modifying agents and the relation with reversal of anthracycline resistance

Pinedo, H. M., Schuurhuis, G. J., Broxterman, H. J., van Kalken, C. K., Kuiper, C. M. & Lankelma, J., 1990, In : International Journal of Cancer. 46, p. 330-336

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Distribution of multidrug resistance-associated P-glycoprotein in normal and neoplastic human tissue

van der Valk, P., van Kalken, C. K., Ketelaars, H., Broxterman, H. J., Scheffer, G., Kuijper, C. M., Tsuruo, T., Lankelma, J., Meijer, C. J. L. M. & Pinedo, H. M., 1990, In : Annals of Oncology. 1, p. 56-64

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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7 Downloads (Pure)

Do antimetabolites interfere with the glycosylation of cellular glycoconjugates

Peters, G. J., Pinedo, H. M., Ferwerda, W., de Graaf, T. W. & van Dijk, W., 1990, In : European Journal of Cancer. 26, p. 516-523

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Doppler measurements of fetal and uteroplacental circulations: Relationship with umbilical venous blood gases measured at cordocentesis

Bilardo, C. M., Nicolaides, K. H. & Campbell, S., 1990, In : American Journal of Obstetrics and Gynecology. 162, 1, p. 115-120

Research output: Contribution to journalArticleAcademicpeer-review

DOWN-SYNDROOM IN NOORDOOST-NEDERLAND; VERWACHTING EN REALITEIT 1981-986

Cornel, M. C., Tuerlings, J. H. A. M., Breed, A. S. P. M. & Ten Kate, L. P., 1 Jan 1990, In : Nederlands Tijdschrift voor Geneeskunde. 134, 38, p. 1852-1855 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of intrastriatal apomorphine on changes in switching behaviour induced by the glutamate agonist AMPA injected into the cat caudate nucleus

Jaspers, R. M. A., de Vries, T. J. & Cools, A. R., 26 Mar 1990, In : Behavioural Brain Research. 37, 3, p. 247-254 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Efficacy and safety of ibopamine in congestive heart failure

van Veldhuisen, D. J., Girbes, A. R. J., Crijns, H. J., Smit, A. J., de Graeff, P. A. & Lie, K. I., 1 Jan 1990, In : Journal of Autonomic Pharmacology. 10, p. s115-s121

Research output: Contribution to journalArticleAcademicpeer-review

Electromechanical delay in the vastus lateralis muscle during dynamic isometric contractions

Vos, E. J., Mullender, M. G. & van Ingen Schenau, G. J., 1 Nov 1990, In : European Journal of Applied Physiology and Occupational Physiology. 60, 6, p. 467-471 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Enhancement in switching motor patterns following local application of the glutamate agonist AMPA into the cat caudate nucleus

Jaspers, R. M. A., de Vries, T. J. & Cools, A. R., 26 Mar 1990, In : Behavioural Brain Research. 37, 3, p. 237-246 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

EVALUATIE VAN KLINISCHE-PATHOLOGISCHE CONFERENTIES MET BEHULP VAN EEN PROGRAMMA VOOR 'COMPUTER-ONDERSTEUNDE' DIAGNOSE; ANALYSE VAN EEN HONDERDTAL ZIEKTEGESCHIEDENISSEN

Kerkhof, P. L. M., Helder, J., Van Dieijen-Visser Schreuder, M. P. J. J. A., Van Dijke, C. P. H. & Gill, K., 1 Jan 1990, In : Nederlands Tijdschrift voor Geneeskunde. 134, 32, p. 1552-1556 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Evaluation of postprocessing dual-energy methods in quantitative computed tomography: Part 2. Practical aspects

Van Kuijk, C., Grashuis, J. L., Steenbeek, J. C. M., SchÜtte, H. E. & Trouerbach, W. T., 1990, In : Investigative Radiology. 25, 8, p. 882-889 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Evaluation of postprocessing dual-energy methods in quantitative computed tomography: Part 1. Theoretical considerations

Van Kuijk, C., Grashuis, J. L., Steenbeek, J. C. M., SchÜtte, H. E. & Trouerbach, W. T., 1990, In : Investigative Radiology. 25, 8, p. 876-881 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

EVALUATION OF POSTPROCESSING DUAL-ENERGY METHODS IN QUANTITATIVE COMPUTED-TOMOGRAPHY .2. PRACTICAL ASPECTS

VANKUIJK, C., GRASHUIS, JL., STEENBEEK, JCM., SCHUTTE, HE. & TROUERBACH, WT., Aug 1990, In : Investigative Radiology. 25, 8, p. 882-889

Research output: Contribution to journalArticleAcademicpeer-review

EVALUATION OF POSTPROCESSING METHODS FOR QUANTITATIVE MEASUREMENTS WITH DUAL ENERGY CT

VANKUIJK, C., GRASHUIS, JL. & STEENBEEK, JCM., Feb 1990, In : Calcified Tissue International. 46, 2, p. 137-137

Research output: Contribution to journalMeeting AbstractAcademic

Expression of human adenosine deaminase in mice transplanted with hemopoietic stem cells infected with amphotropic retroviruses

van Beusechem, V. W., Kukler, A., Einerhand, M. P., Bakx, T. A., van der Eb, A. J., van Bekkum, D. W. & Valerio, D., 1 Sep 1990, In : Journal of Experimental Medicine. 172, 3, p. 729-36 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Factors in prostate cancer metastasis

Geldof, A. A. & Rao, B. R., 1 Jan 1990, In : Anticancer Research. 10, 5 A, p. 1303-1306 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Follow-up of regional myocardial T2 relaxation times in patients with myocardial infarction evaluated with magnetic resonance imaging

Hanno Krauss, X., van der Wall, E. E., van der Laarse, A., Doornbos, J., de Roos, A., Matheijssen, N. A. A., van Dijkman, P. R. M., van Voorthuisen, A. E. & Bruschke, A. V. G., 1 Jan 1990, In : European Journal of Radiology. 11, 2, p. 110-119 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

FULMINANTE SEPSIS DOOR STREPTOCOCCUS SUIS

Van Jaarsveld, B. C., Van Kregten, E., Van Kesteren, R. G., Rozenberg-Arska, M. & Bartelink, A. K. M., 1 Jan 1990, In : Nederlands Tijdschrift voor Geneeskunde. 134, 30, p. 1462-1464 3 p.

Research output: Contribution to journalShort surveyAcademicpeer-review

Fulminant falciparum malaria

Smit, W. M., Oudemans-van Straaten, H. M. & Zandstra, D. F., 1 Aug 1990, In : Intensive Care Medicine. 16, 8, p. 517-519 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Gadolinium-enhanced magnetic resonance imaging in acute myocardial infarction

van Dijkman, P. R. M., van der Wall, E. E., de Roos, A., Doornbos, J., van der Laarse, A., Matheijssen, N. A. A., van Rossum, A. C., van Voorthuisen, A. E. & Bruschke, A. V. G., 1 Jan 1990, In : European Journal of Radiology. 11, 1, p. 1-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hydrops fetalis associated with red cell pyruvate kinase deficiency

Hennekam, R. C., Beemer, F. A., Cats, B. P., Jansen, G. & Staal, G. E., 1990, In : Genetic Counseling. 1, 1, p. 75-9 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of a 43‐kda nuclear antigen associated with proliferation by monoclonal antibody k 112

Quak, J. J., Dongen, G. V., Koken, M. A. E., Brakkee, J. G. P., Scheper, R. J., Balm, A. J. M., Jong, L. D., Snow, G. B. & Meijer, C. J. L. M., 1 Jan 1990, In : International Journal of Cancer. 46, 1, p. 50-55 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of the cystic fibrosis gene (II)

Ten Kate, L. P., Cornel, M. C., Haayer, E. J., Tijmstra, T., Van Den Berg-Rust, C., De Ruiter, P. & Beekhuis, J. R., 1 Jan 1990, In : British Medical Journal. 300, 6730, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

Immunoglobulins in the prophylaxis of parvovirus B19 infection

Schwarz, T. F., Roggendorf, M., Hottenträger, B., Modrow, S., Deinhardt, F. & Middeldorp, J., Nov 1990, In : Journal of Infectious Diseases. 162, 5, p. 1214

Research output: Contribution to journalArticleAcademicpeer-review

Incidence of tumours in the cervical region of the rat after treatment with radiation and hyperthermia

Sminia, P., Jansen, W., Haveman, J. & Van Dijk, J. D., Feb 1990, In : International Journal of Radiation Biology. 57, 2, p. 425-36 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Inhibition of neurotransmitter release and adenylate cyclase activity by opioids: Ontogeny of functional mu, delta and kappa receptors in rat brain

de Vries, T. J., Hogenboom, F., Mulder, A. H. & Schoffelmeer, N. M., 1 Jan 1990, New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. Van Ree, J. M., Mulder, A. H., Wiegant, V. M., Van Wimersma Greidanus, T. B., Van Ree, J. M., Mulder, A. H., Wiegant, V. M. & Van Wimersma Greidanus, T. B. (eds.). Elsevier Science Publishers B.V., 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Interaction of N-hydroxy(sulfo)succinimide active esters with the reduced folate/methotrexate transport system from human CCRF-CEM leukemia cells

Jansen, G., Westerhof, G. R., Kathmann, G. A. M., Schornagel, J. H. & Rijksen, G., 1990, In: "Chemistry and Biology of Pteridines". Curtius, H. C., Ghisla, S. & Blau, N. (eds.). Walter de Gruyter, p. 1272-1275 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

In vitro models of cardiac ischaemia and the evaluation of the cardioprotective effects of calcium antagonists and other anti-ischaemic drugs

Hugtenburg, J. G., Beckeringh, J. J., Boddeke, H. W. G. M., Heijnis, J. B., Jap, T. J. W., Mathy, M. J. & Van Zwieten, P. A., 1 Jan 1990, In : Progress in Pharmacology and Clinical Pharmacology. 8, 2, p. 19-35 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

In vivo inhibition of the pyrimidine de novo enzyme dihydrorotic acid dehydrogenase by brequinar sodium (DUP-785; NSC 368390) in mice and patients

Peters, G. J., Schwartsmann, G., Nadal, J. C., Laurensse, E. J., van Groeningen, C. J. & Pinedo, H. M., 1990, In : Cancer Research. 50, p. 4644-4649

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Islet-amyloid polypeptide in human plasma

Van Jaarsveld, B. C., Hackeng, W. H. L., Nieuwenhuis, M. G., Erkelens, D. W., Geerdink, R. A. & Lips, C. J. M., 6 Jan 1990, In : The Lancet. 335, 8680, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

Isolated mouse atrium as a model to study anthracycline cardiotoxicity. The role of the beta-adrenoceptor system and reactive oxygen species

de Jong, J., Schoofs, P. R., Onderwater, R. C. A., van der Vijgh, W. J. F., Pinedo, H. M. & Bast, A., 1990, In : Research Communications in Chemical Pathology and Pharmacology. 68, p. 275-289

Research output: Contribution to journalArticleAcademicpeer-review

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Lack of a dopamine autoreceptor selective profile of B-HT 920 in functional in vitro model systems of D2 receptors in rat striatum

Drukarch, B., Schepens, E., Dolleman-Van der Weel, M. J., De Boer, P., Van Vliet, B. J. & Stoof, J. C., 9 Oct 1990, In : European Journal of Pharmacology. 187, 2, p. 257-69 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lack of effect of lithium on the renal response to DA1‐dopamine receptor stimulation by fenoldopam in normal man [see comments]

Girbes, AR., Smit, AJ., Meijer, S. & Reitsma, WD., 1 Jan 1990, In : British Journal of Clinical Pharmacology. 29, 4, p. 413-415 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lithium and the renal response to gludopa, fenoldopam and dopamine [letter; comment]

Girbes, AR., Smit, AJ., Meijer, S. & Reitsma, WD., 1 Jan 1990, In : British Journal of Clinical Pharmacology. 30, 4, p. 652-653 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Macrophages and the activity of high endothelial venules. The effect of interferon-gamma

Mebius, R. E., Hendriks, H. R., Brevé, J. & Kraal, G., Jul 1990, In : European Journal of Immunology. 20, 7, p. 1615-8 4 p.

Research output: Contribution to journalArticleAcademicpeer-review