Find Research Outputs

Search concepts
Selected filters
1973

Salicylate induced consumption coagulopathy

Pinedo, H. M., van de Putte, L. B. M. & Loeliger, W. A., 1973, In : Annals of the Rheumatic Diseases. 32

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
28 Downloads (Pure)

Treatment of vitiligo by local application of betamethasone 17-valerate in a dimethyl sulfoxide cream base

Koopmans-van Dorp, B., Goedhart-van Dijk, B., Neering, H. & Vandijk, E., 1973, In : BMC dermatology. 146, 5, p. 310-314

Research output: Contribution to journalArticleAcademicpeer-review

1974

Muscle length and neuromuscular transmission in the frog

IJpeij, D. L., Kerkhof, P. L. M. & Bobbert, A. C., 1 Dec 1974, In : Pflügers Archiv European Journal of Physiology. 347, 4, p. 309-322 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Photoreduction of plastoquinone to plastosemiquinone in spinach chloroplasts at -400°C

Pulles, M. P. J., Kerkhof, P. L. M. & Amesz, J., 1 Oct 1974, In : FEBS Letters. 47, 1, p. 143-145 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

1976

Device for constant Sc infusion of methotrexate: Plasma results in mice

Pinedo, H. M., Dedrick, R. L. & Zaharko, D. A., 1976, In : Cancer treatment reports. 60, p. 889

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Downloads (Pure)

Evidence for early recruitment of granulocyte precursors during high dose methotrexate infusion in mice

Pinedo, H. M., Zaharko, D. A., Chabner, B. A. & Bull, J. M., 1976, In : Blood. 48, p. 301

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Downloads (Pure)

The reversal of methotrexate cytotoxicity to mouse bone marrow cells by leucovorin and nucleosides

Pinedo, H. M., Zaharko, D. A., Bull, J. M. & Chabner, B. A., 1976, In : Cancer Research. 36, p. 4418

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Downloads (Pure)
1977

EORTC protocol for therapy of metastatic soft tissue sarcomas, a randomized trial

Pinedo, H. M., Vendrik, C. P. J., Staquet, M., Kenis, Y. & Sylvester, R., 1977, In : European Journal of Cancer. 13, p. 765

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Downloads (Pure)

Phasic left ventricular volume in the isolated heart

Baan, J., Elzinga, N. J., Kerkhof, P. L. M. & Moene, R. J., 1 Jan 1977, In : Federation Proceedings. 36, 3

Research output: Contribution to journalArticleAcademicpeer-review

The relative contribution of drug concentration and duration of exposure to mouse bone marrow toxicity during continuous methotrexate infusion

Pinedo, H. M., Zaharko, D. A., Bull, J. M. & Chabner, B. A., 1977, In : Cancer Research. 37, p. 445

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Downloads (Pure)

The role of drug concentration, duration of exposure and endogeneous metabolites in determining methotrexate cytotoxicity

Pinedo, H. M., Zaharko, D. A., Bull, J. M. & Chabner, B. A., 1977, In : Cancer treatment reports. 61, p. 709

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
7 Downloads (Pure)
1978

Characterization of methotrexate (MTX) recovered from the urine of high dose patients for purpose of clinical re use

Leyva, A., Baygell, P. D., van Loenen, A. C., van Asten, P., Pintus, C., Spreafico, F. & Pinedo, H. M., 1978, In : European Journal of Cancer. 14, p. 1017

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Downloads (Pure)

Soft tissue sarcoma in adults. Randomized Trials in Cancer: A Critical Review by Sites

Pinedo, H. M., Rosenberg, S., Nieuwenhuis, M. G. & Chabner, B. A., 1978, Monograph series of the European Organization for Research on Treatment of Cancer. Raven Press, p. 359-375

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Open Access
File
7 Downloads (Pure)

Study of diamminedichlorocisplatinum in advanced soft tissue sarcoma (protocol 62781)

Pinedo, H. M., Vendrik, C. P. J., Staquet, M. & Sylvester, R., 1978, In : European Journal of Cancer. 14, p. 1149

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Downloads (Pure)
1979

Adjuvant treatment of soft tissue sarcoma in children and adults

Bramwell, V. H. C., Pinedo, H. M., Voûte, P. A. & Rosenberg, S. A., 1979, Adjuvant Therapy and Markers. Springer Verlag, p. 60

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Open Access
File
39 Downloads (Pure)

Cis diammine-dichloro platinum single drug and combination chemotherapy in the treatment of genitorinary cancer

Sloter, G. & Pinedo, H. M., 1979, Bladder Tumors and other Topics in Urological Oncology. Plenum Publishing Corporation, p. 31-34

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Open Access
File
4 Downloads (Pure)

Combination chemotherapy with cis-diammine-dichloro platinum, vinblastine and bleomycin in advanced testicular non seminoma

Stoter, G., Vendrik, C. P. J., Struyvenberg, A., Sleijfer, D. T., Schraffordt Koops, H., van Oosterom, A. T. & Pinedo, H. M., 1979, In : Lancet. 8123, p. 941

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
37 Downloads (Pure)

Effects of age on aortic pressure-diameter and elastic stiffness-stress relationships in unanesthetized sheep

Pagani, M., Mirsky, I., Baig, H., Manders, W. T., Kerkhof, P. & Vatner, S. F., Mar 1979, In : Circulation Research. 44, 3, p. 420-9 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

EORTC phase II study of cisplatin in CYVADIC resistant soft tissue sarcoma

Bramwell, V. H. C., Brugarolas, A., Mouridsen, H. T., Cheix, F., de Jager, R., van Oosterom, A., Vendrik, C. P., Pinedo, H. M., Sylvester, R. & de Pauw, M., 1979, In : European Journal of Cancer. 15, p. 1511

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
31 Downloads (Pure)

Evaluation of adjuvant therapy in soft tissue sarcoma, a collaborative multidisciplinary study

Pinedo, H. M., Vendrik, C. P. J., Bramwell, V. H. C., van Slooten, E. A., Deakin, D. P., van Unnik, J. A. M., Staquet, M. J., Sylvester, R. & Bonadonna, G., 1979, In : European Journal of Cancer. 15, p. 811

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Downloads (Pure)

Genito-urinary tumors

Stoter, G., Rozencweig, M. & Pinedo, H. M., 1979, Cancer Chemotherapy Annual. Excerpta Medica, p. 317

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Open Access
File
5 Downloads (Pure)

Hexa CAF combination in pretreated ovarian carcinoma

Neijt, J. P. & Pinedo, H. M., 1979, In : New England Journal of Medicine. 300, p. 676

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
7 Downloads (Pure)

Partial remission of advanced adenoid cystic carcinoma obtained with adriamycin: A case report with a review of literature

Vermeer, R. J. & Pinedo, H. M., 1979, In : Cancer. 43, p. 1604

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
35 Downloads (Pure)

Radiotoxicity of 111indium

Kraal, G. & Geldof, A. A., 14 Dec 1979, In : Journal of Immunological Methods. 31, 1-2, p. 193-195 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

The interval force relationship, a technique for the evaluation of the cardiac toxicity for anthracycline analogues

Breed, J. G. S., Zimmerman, A. N. E., Meyler, F. L. & Pinedo, H. M., 1979, In : Cancer treatment reports. 63, p. 869

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Downloads (Pure)
1980

An update of the Dutch multicenter PVB study in disseminated testicular non seminomas

Stoter, G., Vendrik, C. P. J., Struyvenberg, A., Brouwers, T. M., Sleyfer, D. T., Schraffordt Koops, H., van Oosterom, A. T. & Pinedo, H. M., 1980, Therapeutic Progress in Ovarian Cancer Testicular Cancer and the Sarcomas. Martinus Nijhoff Publishers, p. 247-251

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Open Access
File
32 Downloads (Pure)

Complete remission of mediastinal tumors with cis-dichloro-diammine platinum (II) combination chemotherapy

van Hoesel, Q. G. C. M. & Pinedo, H. M., 1980, In : Cancer treatment reports. 64, p. 319

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
7 Downloads (Pure)

COMPUTER ANALYSIS OF THE RELATION BETWEEN EJECTION FRACTION AND VENTRICULAR VOLUME, WITH SPECIAL EMPHASIS ON THE ROLE OF END-SYSTOLIC VOLUME.

Kerkhof, P. L. M., 1 Jan 1980, In : Automedica. 3, 4, p. 207-244 38 p.

Research output: Contribution to journalArticleAcademicpeer-review

Determination of N (phosphonacetyl) L aspartic acid (PALA) in plasma and urine by high pressure liquid chromatography

Lankelma, J., Penders, P. G. M., Leyva, A. & Pinedo, H. M., 1980, In : European Journal of Cancer. 16, p. 1483

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
30 Downloads (Pure)

Effect of methotrexate on 5-phosphoribosyl 1 pyrophosphate levels in L1210 leukemia cells in vitro

Buesa-Perez, J. M., Leyva, A. & Pinedo, H. M., 1980, In : Cancer Research. 40, p. 139

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Downloads (Pure)

Failure of antioxi-dant vitamin E to protect against adriamycin induced cardiotoxicity in the rabbit

Breed, J. G. S., Zimmerman, A. N. E., Dormans, J. A. M. A. & Pinedo, H. M., 1980, In : Cancer Research. 40, p. 2033

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
9 Downloads (Pure)

Parmacokinetic evidence for an enterohepatic circulation in a patient treated with cis dichloro diammine platinum II)

Vermorken, J. B., van der Vijgh, W. J. F. & Pinedo, H. M., 1980, In : Res. Comm. Chem. Pathol. and Pharm.. 28, p. 319

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
6 Downloads (Pure)

Peak left ventricular systolic pressure/ end-systolic volume ratio

Kerkhof, P. L. M. & Baan, J., 1 Jan 1980, In : American Journal of Cardiology. 46, 3, p. 528-529 2 p.

Research output: Contribution to journalLetterAcademicpeer-review

Pump function of the left ventricle evaluated from pressure-volume loops

Kerkhof, PL., 16 Jan 1980, In : Cardiac Dynamics. p. 279 291 p., 4.5.

Research output: Contribution to journalArticleAcademicpeer-review

T-cell differentiation in lethally irradiated and reconstituted mice

Kraal, G., Geldof, A. A. & Boden, D., 1 Jan 1980, In : Cellular Immunology. 49, 1, p. 110-119 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Treatment of advanced soft tissue sarcomas in adults: Past, present and future

Pinedo, H. M. & van Oosterom, A. T., 1980, Therapeutic Progress in Ovarian Cancer Testicular Cancer and the Sarcomas. Martinus Nijhoff Publishers, p. 25-438

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Open Access
File
35 Downloads (Pure)
1981

Concentrations of N (phosphonacetyl) L aspartate (PALA) in plasma and tears in man

Lankelma, J., Penders, P. G. M., Leyva, A., Kleerberg, U. R., Kenny, J. B., Bramwell, V. H. C., McVie, J. G. & Pinedo, H. M., 1981, In : European Journal of Cancer and Clinical Oncology. 17, p. 1199

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
33 Downloads (Pure)

Continuous stroke volume and cardiac output from intra-ventricular dimensions obtained with impedance catheter

Baan, J., Jong, T. T., Kerkhof, P. L., Moene, R. J., van Dijk, A. D., van der Velde, E. T. & Koops, J., 17 Aug 1981, In : Cardiovascular Research. 15, 6, p. 328-334 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Determination of thioproline in plasma using high performance liquid chromatography

Lankelma, J., Penders, P. G. M., Leyva, A. & Pinedo, H. M., 1981, In : Cancer Letters. 12, p. 131

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
37 Downloads (Pure)

Inhibition of cell growth by N (phosphonacetyl) Laspartic acid (PALA) in human and murine cells in vitro

Leyva, A., Appel, H., Smith, P., Lankelma, J. & Pinedo, H. M., 1981, In : Cancer Letters. 12, p. 169-173

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Downloads (Pure)

K88-mediated binding of Escherichia coli outer membrane fragments to porcine intestinal epithelial cell brush borders

Middeldorp, J. M. & Witholt, B., Jan 1981, In : Infection and Immunity. 31, 1, p. 42-51 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lymphokine-mediated stimulation of eosinophil migration in the guinea-pig

van den Berg, W. B., van Tuyl, J., Sminia, P., Jentjens, T. M. & Scheper, R. J., Nov 1981, In : Immunology. 44, 3, p. 481-8 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Quality of institutional participation in multicenter clinical trials

Sylvester, R. J., Pinedo, H. M., de Pauw, M., Staquet, M. J., Buyse, M. E., Renard, J. & Bonadonna, G., 1981, In : New England Journal of Medicine. 305, p. 852

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
35 Downloads (Pure)

Relations between ejection fraction and ventricular volume, and their alteration by chronic beta-blockade

Kerkhof, P. L. M., Baan, J., Buis, B. & Arntzenius, A. C., 1 Jan 1981, In : British Heart Journal. 46, 1, p. 17-22 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Reversal of methotrexate inhibition of Ll2l0 leukemia cells in semi solid medium

Nederbragt, H., Uitendaal, M. P., van der Grint, L., Leyva, A. & Pinedo, H. M., 1981, In : Cancer Research. 41, p. 1193

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Downloads (Pure)

Separation and characterization of hexokinase I subtypes from human erythrocytes

Rijksen, G., Jansen, G., Kraaijenhagen, R. J., Van der Vlist, M. J., Vlug, A. M. & Staal, G. E., 15 Jun 1981, In : Biochimica et Biophysica Acta. Reviews on Cancer. 659, 2, p. 292-301 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

1982

Cardiovascular and biochemical changes in dogs during etomidate-nitrous oxide anaesthesia

van Lambalgen, A. A., Bronsveld, W., van den Bos, G. C., Thijs, L. G. & Teule, G. J. J., 1982, In : Cardiovascular Research. 16, 10, p. 599-606

Research output: Contribution to journalReview articleAcademicpeer-review

Flow through tissue culture system with fast dynamic response

Lankelma, J., Laurensse, E. & Pinedo, H. M., 1982, In : Analytical Biochemistry. 127, p. 340

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
35 Downloads (Pure)