A Case of Lagochilascariasis in Suriname with the Involvement of the ENT System and the Skull Base

Joeri A J Douma, Ralph A E Akrum, Rudie Tjong Tjin Joe, Mike Chan, John Codrington, Stephen Gerold S Vreden

Research output: Contribution to journalArticleAcademicpeer-review


We describe a case of human lagochilascariasis, with skull-base involvement and a chronic and relapsing course after treatment. This rare parasitic infection is usually manifested in the head and neck area, characterized by progressive granulomatous inflammation and the formation of abscesses. Transmission to humans most likely occurs by the consumption of undercooked meat of wild rodents. On the basis of literature studies, we propose the most likely life cycle of the parasite that involves wild feline and rodent species, with humans as accidental hosts. Even in endemic areas, it is very difficult to recognize the disease at an early stage. Progression will eventually lead to involvement of the (central) nervous system, as described in our case. Treatment is often difficult and involves resection and prolonged treatment with anthelmintic drugs. Recurrences are not uncommon and at present, long-term oral administration of ivermectin seems to be the most effective treatment.

Original languageEnglish
Pages (from-to)88-91
Number of pages4
JournalAmerican Journal of Tropical Medicine and Hygiene
Issue number1
Publication statusPublished - 6 Jul 2016

Cite this